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| 1 | Management of gastroesophageal reflux disease: Patient and physician communication challenges and shared decision making显示文摘Gastroesophageal reflux disease(GERD) is a common upper esophageal condition and typical symptoms can include heartburn and sensation of regurgitation while atypical symptoms include chronic cough, asthma, hoarseness, dyspepsia and nausea. Typically, diag-nosis is presumptive given the presence of typical and atypical symptoms and is an indication for empiric therapy. Treatment management can include lifestyle modifications and/or medication therapy with proton pump inhibitor(PPI) class being the preferred and most effective. Complete symptom resolution is not always achieved and long-term PPI therapy can put patients at risk for serious side effects and needless expense. The brain-gut connection and hypervigilance plays an important role in symptom resolution and treatment success, especially in the case of non-PPI responders. Hypervigilance is a combination of increased esophageal sensory sensitivity in combination with exaggerated threat perception surrounding esophageal symptoms. Hypervigilance requires a different approach to GERD managements, where continued PPI therapy and surgery are usually not recommended. Rather, helping physicians and patients understand the brain-gut connection can guide and improve care.Education and reassurance should be the main pillars or treatment. However, it is important not to suggest the symptoms are due to anxiety alone, this often leads to patient dissatisfaction. Patient dissatisfaction with treatment reveals the need for a more patient-centered approach to GERD management and better communication between patients and providers. Shared decision making(SDM) with the incorporation of patient-reported outcomes(PRO) promotes patient adherence and satisfaction. SDM is a joint discussion between clinician and patient in which a mutually shared solution is explored for GERD symptoms. For SDM to work the physician needs to capture patients' perceptions which may not be obtained in the standard interview. This can be done through the use of PROs which promote a dialogue with patients about their symptoms and treatment priorities in the context of the SDM patient encounter. SDM could potentially help in the management of patient expectations for GERD treatment, ultimately positively impacting their health-related quality of life. | Scott Klenzak Igor Danelisen Grace D Brannan Melissa A Holland Miranda AL van Tilburg | 2018 | World Journal of Clinical Cases2018,6,15: | 10 |
| 2 | Immobilization ofFe, Mn and Co tetraphenylporphyrin complexes in MCM-41 and their catalytic activity in cyclohexene oxidationreaction by hydrogen peroxide 显示文摘 | Costa A A Grace F G Julio L ei al | 2008 | J Mol Catal A:Chemical2008,282,: | 1 |
| 3 | Presentation and immunogenicity of viral epitopes on the surface of hybrid hepatitis B virus core paticles produced in bacteria显示文摘 | Clark BE Brown AL Grace Kg | 1990 | J Gen Virol1990,71,: | 1 |
| 4 | On the oscillation of certain third order nonlinear func- tional differential equations显示文摘 | Grace S R Agarwal R P Pavani R at al | 2008 | Appl Math Comput2008,202,: | 1 |
| 5 | Potential net primary production in South-America- Application of a global-model显示文摘 | Raich JW Rastetter EB Melillo JM Kicklighter DW Steudler PA Peterson B J Grace AL Moore B Vorosmarty CJ | 1991 | Ecological Applications1991,1,4: | 1 |
| 6 | DesignConstruction of Bridge Street Bridge--First CFRP Bridge in the United States 显示文摘 | Nabil F Grace Frederick C Navarre el al | 2002 | PCI Journal2002,47,5: | 1 |
| 7 | Presentation and imunogeincoty of viral epitopes on the surface of hybrid heapatitis B virus core particles produced in bacteria显示文摘 | CLARKE BE BROWN AL GRACE KG | 1990 | Journal of Virology1990,71,: | 1 |
| 8 | Presentation and imunogeincoty of viral epitopes on the surface of hybrid heapatitis B virus core particles produced in bacteria显示文摘 | Clarke BE Brown AL Grace KG | 1990 | Journal of Virology1990,71,: | 1 |
| 9 | Preven- tion and management of gastroesophageal varices and variceal hemorrhage in cirrhosis显示文摘 | GARCIA -TSAO G SAN AL A J GRACE ND | 2007 | Hepatology2007,46,3: | 1 |
| 10 | Prevention and management of gastroesophageal varices and variceas hemorrhage in cirrhosis显示文摘 | Garcia-TG Sanyal AJ Grace ND el al | | 0,,03: | 1 |
| 11 | Microsphere-based duplexed immunoassay for influenza virus typing by flow cytometry显示文摘 | Yan X E G Schielke K M Grace et al | 2004 | J Immunological Methods2004,284,: | 1 |
| 12 | A phase ii study of anti- epidermal growth factor receptor radioimmurmtherapy in the treatment of glioblastoma muhifonne 显示文摘 | Li L Quang TS Gracely EJ e! al | 2010 | J Neurosurg2010,113,2: | 1 |
| 13 | 理想上颌侧切牙垂直向位置的评价研究显示文摘目的:评价和比较正畸医师、全科牙医以及非牙科专业人员对理想上颌侧切牙垂直向位置的选择。方法:参与研究的评判者分3组共120人.每组40人。评判者在观看理想微笑动画的时候指出他们喜欢的上颌侧切牙垂直向位置。由软件(Perceptometrics)播放动画并比较评判者的反应。每个评判者参与两个类似的实验.一个是来判断他们最喜欢的上颌侧切牙垂直向位置,另一个是他们所能接受的这个位置的变异范围。对资料进行方差分析和post—hoc Scheffe两两比较方差分析,检验3组之间的差别。结果:3组评判者对理想上颌侧切牙垂直向位置判断的均值间差别没有统计学意义(P〉0.05),3组均值为上颌侧切牙切缘高于切端平面0.6mm。没有评判者喜欢上颌侧切牙切缘与切端平面平齐。正畸医师和全科牙医对上颌侧切牙垂直向位置变化的可接受范围比非牙科专业人员要小。所有评判者的平均可接受范围如下:上界是高于切端平面1.0mm,下界是高于切端平面0.3mm。结论:本研究中的评判者认为理想上颌侧切牙切缘应高于切端平面约0.5mm左右。当侧切牙轻微龈向高于切端平面时看上去最自然,高出的距离有一个可接受的范围。 | Kevin L. King DMD, MS Carla A. Evans DDS, DMSc Grace Viana, MSc Ellen BeGole, PhD Ales Obrez, DMD, PhD. Grace Viana, MSc Ellen BeGole, PhD Ales Obrez DMD, PhD. 陈贵(译) 姜若萍(审) | 2010 | 中国口腔医学继续教育杂志2010,13,2: | 0 |