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| 1 | Catheter ablation of atrial fibrillation facilitated by preprocedural three-dimensional transesophageal echocardiography: Long-term outcome显示文摘AIM To evaluate the long-term outcome of catheter ablation of atrial fibrillation(AF) facilitated by preprocedural threedimensional(3-D) transesophageal echocardiography.METHODS In 50 patients, 3D transesophageal echocardiography(3D TEE) was performed immediately prior to an ablation procedure(paroxysmal AF: 30 patients, persistent AF: 20 patients). The images were available throughout the ablation procedure. Two different ablation strategies were used. In most of the patients with paroxysmal AF, the cryoablation technique was used(Arctic Front Balloon, Cryo Cath Technologies/Medtronic; group A2). In the other patients, a circumferential pulmonary vein ablation was performed using the CARTO system [Biosense Webster; group A1(paroxysmal AF), group B(persistent AF)]. Success rates and complication rates were analysed at 4-year follow-up.RESULTS A 3D TEE could be performed successfully in all patients prior to the ablation procedure and all four pulmonaryvein ostia could be evaluated in 84% of patients. The image quality was excellent in the majority of patients and several variations of the pulmonary vein anatomy could be visualized precisely(e.g., common pulmonary vein ostia, accessory pulmonary veins, varying diameter of the left atrial appendage and its distance to the left superior pulmonary vein). All ablation procedures could be performed as planned and almost all pulmonary veins could be isolated successfully. At 48-mo followup, 68.0% of all patients were free from an arrhythmia recurrence(group A1: 72.7%, group A2: 73.7%, group B: 60.0%). There were no major complications.CONCLUSION3 D TEE provides an excellent overview over the left atrial anatomy prior to AF ablation procedures and these procedures are associated with a favourable long-term outcome. | Klaus Kettering Felix Gramley Stephan von Bardeleben | 2017 | World Journal of Cardiology2017,9,6: | 3 |
| 2 | Catheter ablation of atrial fibrillation: Radiofrequency catheter ablation for redo procedures after cryoablation显示文摘AIM: To evaluate the effectiveness of two different strategies using radiofrequency catheter ablation for redo procedures after cryoablation of atrial fibrillation.METHODS: Thirty patients(paroxysmal atrial fibrillation: 22 patients,persistent atrial fibrillation: 8 patients) had to undergo a redo procedure after initially successful circumferential pulmonary vein(PV) isolation with the cryoballoon technique(Arctic Front Balloon,CryoCath Technologies/Medtronic).The redo ablation procedures were performed using a segmental approach or a circumferential ablation strategy(CARTO;Biosense Webster) depending on the intra-procedural findings.After discharge,patients were scheduled for repeated visits at the arrhythmia clinic.A 7-day Holter monitoring was performed at 3,12 and 24 mo after the ablation procedure.RESULTS: During the redo procedure,a mean number of 2.9 re-conducting pulmonary veins(SD ± 1.0 PVs) were detected(using a circular mapping catheter).In 20 patients,a segmental approach was sufficient to eliminate the residual pulmonary vein conduction because there were only a few recovered pulmonary vein fibres.In the remaining 10 patients,a circumferential ablation strategy was used because of a complete recovery of the PV-LA conduction.All recovered pulmonary veins could be isolated successfully again.At 2-year follow-up,73.3% of all patients were free from an arrhythmia recurrence(22/30).There were no major complications.CONCLUSION: In patients with an initial circumferential pulmonary vein isolation using the cryoballoon technique,a repeat ablation procedure can be performed safely and effectively using radiofrequency catheter ablation. | Klaus Kettering Felix Gramley | 2013 | World Journal of Cardiology2013,5,8: | 2 |
| 3 | Atrial fibrillation is asso- ciated with cardiac hypoxia 显示文摘 | Gramley F Lorenzen J Jedamzik B | 2010 | Cardiol Pathol2010,19,2: | 1 |
| 4 | Association of echocardiographic atrial size and atrial fibrosis in a sequential model of congestive heart failure and atrial fibrillation显示文摘 | Christian Knackstedt Felix Gramley Thomas Schimpf Karl Mischke Markus Zarse Jurgita Plisiene Michael Schmid Johann Lorenzen Dirk Frechen Philipp Neef Peter Hanrath Malte Kelm Patrick Schauerte | 2008 | Cardiovascular Pathology2008,,5: | 1 |
| 5 | Atrial fibrosis and atrial fibrillation: The role of the TGF-β 1 signaling pathway显示文摘 | Felix Gramley Johann Lorenzen Eva Koellensperger Klaus Kettering Christian Weiss Thomas Munzel | 2009 | International Journal of Cardiology2009,,3: | 1 |
| 6 | Atrial fibrosis and atrial fibril- lation: the role of the TGF-β1 signaling pathway显示文摘 | Gramley F Lorenzen J Koellensperger E | 2010 | Int J Cardiol2010,143,3: | 1 |
| 7 | McLajghlin University hospital and Medical park显示文摘 | GramLey WC Curits P | | Continuous quality improvement in health case0,4,: | 1 |
| 8 | Atrial fibrillation is associated with cardiac hypoxia显示文摘 | Gramley F Lorenzen J Jedamzik B | | 0,,02: | 1 |
| 9 | Atrial fibrosisand atrial fibrillation:the role of the TGF-β signaling pathway显示文摘 | Gramley F Lomnzen J Koellensperger E el al | 2010 | J Cardiol2010,143,3: | 1 |
| 10 | Atrial fibrosis and atrial fibrillation: the role of the TGF-β1 signaling pathway显示文摘 | Gramley F Lorenzen J Koellensperger E | 2010 | Int J Cardiol2010,143,3: | 1 |
| 11 | Atrial fibrosis and atrial fibrillation:the role of the TGF-β1 signaling pathway显示文摘 | GRAMLEY F LORENZEN J KOELLENSPERGER E | 2010 | Int J Cardiol2010,43,3: | 1 |
| 12 | 显示文摘 | Gramley WA Asghar A Frierson HF | 1999 | J Clin Microbiol1999,37,7: | 1 |
| 13 | Association of echocardiographic atrial size and at- rial fibrosis in a sequential model of congestive heart failure and atrial fibrillation显示文摘 | KNACKSTEDT C GRAMLEY F SCHIMPF T | 2008 | Cardiovasc Pathol2008,17,: | 1 |
| 14 | Decreased plasminogen activator inhibitor and tissue metalloproteinase inhibitor expression may promote increased metalloproteinase activity with increasing duration of human atrial fibrillation 显示文摘 | Gramley F Lorenzen J Plisiene J | 2007 | J Cardiovasc Electrophysiol2007,18,10: | 1 |
| 15 | Can HMG-CoA Reductase inhibitors(statins) reduce the stability of atherosclerosis plaques by activating matrix metalloproteinase显示文摘 | Schmidt A Budecke E | 1999 | Basic Res Cardiol1999,94,: | 1 |
| 16 | Atrial fibrosis and atrial fibrillation the role of the TGF -β, signaling pathway显示文摘 | Gramley F Lorenzen J Koellensperger E | 2010 | Int J Cardiol2010,143,3: | 1 |
| 17 | Atrial fibrosis and atrial fibrillation: The role of the TGF-beta(1) signaling pathway显示文摘 | GRAMLEY F LORENZEN J KOELLENSPERG- ER E | 2010 | Int J Cardiol2010,143,: | 1 |
| 18 | Hypoxia and myocardial remodeling in human cardiac allografts: a time-course study 显示文摘 | GRAMLEY F LORENZEN J PEZZELLA F | 2009 | J Heart Lung Transplant2009,28,: | 1 |
| 19 | Atrial fibrosis and atrial fibrillation:the role of the TGF-betal signaling pathway显示文摘 | Gramley F Lorenzen J Koellensperger E | | 0,,: | 1 |
| 20 | Update on pharmacologic approaches to prevent thromboembolism in atrial fibrillation:are thrombin and factor Xa inhibitors the ultimate answer?显示文摘 | Wolfram O Hammwoehner M Gramley F | 2011 | Curr Vasc Pharmacol2011,9,3: | 1 |