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| 1 | Passive expansion of sub-maximally dilated transjugular intrahepatic portosystemic shunts and assessment of clinical outcomes显示文摘AIM To assess for passive expansion of sub-maximally dilated transjugular intrahepatic portosystemic shunts(TIPS) and compare outcomes with maximally dilated TIPS.METHODS Polytetrafluoroethylene covered TIPS(Viatorr) from July 2002 to December 2013 were retrospectively reviewed at two hospitals in a single institution. Two hundred and thirty patients had TIPS maximally dilated to 10 mm(m TIPS), while 43 patients who were at increased risk for hepatic encephalopathy(HE), based on clinical evaluation or low pre-TIPS portosystemic gradient(PSG), had 10 mm TIPS sub-maximally dilated to 8 mm(sm TIPS). Group characteristics(age, gender, Model for End-Stage Liver Disease score, post-TIPS PSG and clinical outcomes were compared between groups, including clinical success(ascites or varices), primary patency,primary assisted patency, and severe post-TIPS HE. A subset of fourteen patients with sm TIPS underwent follow-up computed tomography imaging after TIPS creation, and were grouped based on time of imaging(< 6 mo and > 6 mo). Change in diameter and crosssectional area were measured with 3D imaging software to evaluate for passive expansion.RESULTS Patient characteristics were similar between the sm TIPS and m TIPS groups, except for pre-TIPS portosystemic gradient, which was lower in the sm TIPS group(19.4 mm Hg ± 6.8 vs 22.4 mm Hg ± 7.1, P = 0.01). Primary patency and primary assisted patency between sm TIPS and m TIPS was not significantly different(P = 0.64 and 0.55, respectively). Four of the 55 patients(7%) with sm TIPS required TIPS reduction for severe refractory HE, while this occurred in 6 of the 218 patients(3%) with m TIPS(P = 0.12). For the 14 patients with follow-up computed tomography(CT) imaging, the median imaging follow-up was 373 d. There was an increase in median TIPS diameter, median percent diameter change, median area, and median percent area change in patients with CT follow-up greater than 6 mo after TIPS placement compared to follow-up within 6 mo(8.45 mm, 5.58%, 56.04 mm^2, and 11.48%, respectively, P = 0.01).CONCLUSION Passive expansion of sm TIPS does occur but clinical outcomes of sm TIPS and m TIPS were similar. Sub-maximal dilation can prevent complications related to overshunting in select patients. | Michael C Hsu Charles N Weber S William Stavropoulos Timothy W Clark Scott O Trerotola Richard D Shlansky Goldberg Michael C Soulen Gregory J Nadolski | 2017 | World Journal of Hepatology2017，9，12： | 11 |
| 2 | Clinical parameters linked with malignancy in endometrial polyps显示文摘 | GREGORIOU O KONIDARIS S VRACHNIS N | 2009 | Climacteric2009，12，5： | 1 |
| 3 | Use of amino-terminal pro-B-type natriuretic peptide to guide outpatient therapy of patients with chronic left ventricular systolic dysfunction 显示文摘 | JAMES L JANUZZI JR MD SHAFIQ U REHMAN M D ASIM A MOHAMMED M D ANJU BHARDWAJ M D LINDA BARAJAS R N JUSTINE BARAJAS HAN-NA KIM M D MPH AARON L BAGGISH M D RORY B WEINER M D ANNABEL CHEN-TOURNOUX MD JANE E MARSHALL RDCS STEPHANIE A MOORE M D WILLIAM D CARLSON M D GREGORY D LEWIS M D JORDAN SHIN M D DOROTHY SULLIVAN ANP KIMBERLY PARKS D O THOMAS J WANG M D SHAWN A GREGORY M D SHANMUGAM UTHAMALINGAM M D MARC J SEMIGRAN M D | 2011 | J Am Coll Cardiol2011，58，18： | 1 |
| 4 | Gonadotropin-releasing hormone analogue plus hormone replacement therapy for the treatment of endometriosis:a randomized controlled trial显示文摘 | Konidaris S Vitoratos N | 1997 | Int J Fertil Womens Med1997，42，6： | 1 |
| 5 | Effect of pentoxifylline on vascular endothelial growth facror C and ilk-1 expression on endometrial implants in the rat endometriosis model显示文摘 | VLAHOS N F GREGORIOU O DELIVELIOTOU A | 2010 | Fertil Steril2010，93，4： | 1 |
| 6 | Clinical parameters linked with malignancy in endometrial polyps 显示文摘 | Gregoriou O Konidaris S Vrachnis N | 2009 | Climacteric2009，12，5： | 1 |
| 7 | Clinical parameters linked with malignancy in endometrial polyps显示文摘 | Gregoriou O Konidaris S Vrachnis N | 2009 | Climacteric2009，12，5： | 1 |
| 8 | Treatment of idiopathic oligozoospermia with an alpha-blocker:A placebo-controlled double-blind trial显示文摘 | Gregoriou O Vitorators N Papadias C | 1997 | Int J Fertil Womens Med1997，42，5： | 1 |
| 9 | Prevention and Management of Ovarian Hyperstimulation Syndrome显示文摘 | Vlahos N F Gregoriou O | 2006 | Ann N Y Acad Sci2006，15，2： | 1 |
| 10 | Treatment of idi- opathic oligozoospermia with an alpha-blocker: a placebo-controlled double-blind trial 显示文摘 | Gregoriou O Vitoratos N Papadias C | 1997 | Int J Fertil Womens Med1997，42，5： | 1 |
| 11 | Effect of tibolone on postmenopausal women with myomas显示文摘 | Gregoriou O Vitoratos N Papadias C Konidaris S CostomenosD Chryssikopoulos A | 1997 | Maturitas1997，27，2： | 1 |
| 12 | Semicarbazide fo_mation in flour and bread 显示文摘 | GREGORY O N TIMOTHY H B GREGORY W D | 2008 | J Agric Food Chem2008，56，6： | 1 |
| 13 | Clinical value of cre- atinine kinase in the diagnosis of ectopic pregnancy显示文摘 | Vitoratos N Gregoriou O Papadias C | 1998 | Gynecol Obstet Invest1998，46，2： | 1 |
| 14 | Clinical parameters linked with malignancy in endometrial polyps显示文摘 | Gregoriou O Konidaris S Vrachnis N | 2009 | Climacteric2009，12，： | 1 |
| 15 | Clinical parameters linked with malignancy in endometrial polyps显示文摘 | Gregoriou O Konidaris S Vrachnis N | 2009 | Climacteric2009，12，： | 1 |
| 16 | Semicarbazide formation in flour and bread显示文摘 | Gregory O N Timothy H B Gregory W D | 2008 | Journal of Agricultural and Food Chemistry2008，56，6： | 1 |
| 17 | Clinical parameters linked with malignancy in endometrial polyps显示文摘 | Gregoriou O Konidaris S Vrachnis N | 2009 | Climacteric2009，12，5： | 1 |
| 18 | Gonadotropin - releasing hormone analogue plus hormone replacament therapy for the treatment of endometriosis: a randomized controlled trial 显示文摘 | Gregoriou O Konidaris S Vitoratos N | 1997 | Int J Fertile Womens Med1997，42，6： | 1 |
| 19 | Randomized controlled trial comparing superovulation with letrozole versus recombinant follicle-stimulating hormone combined with intrauterine insemination for couples with unexplained infertility who had failed clomiphene citrate stimulation and intrauterine insemination显示文摘 | Gregoriou O Vlahos N F Konidaris S | 2008 | Fertil Steril2008，90，3： | 1 |
| 20 | Inferring black carbon content and specific absorption from Aerosol Robotic Network (AERONET) aerosol retrievals 显示文摘 | L S Gregory O Dubovik B N Holben | 2005 | Journal of Geophysical Research2005，，： | 1 |
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