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| 1 | Monosomy 22 and trisomy 14 may be early events in the tumorigenesis of adult granulosa cell tumor 显示文摘 | Van den Berghe I Dal CP De Groef K | 1999 | Cancer Genet Cytogenet1999，112，1： | 1 |
| 2 | MMPs in the neuroreti- na and optic nerve: modulators of glaucoma pathogenesis and re- pair 显示文摘 | De Groef L Van Hove I Dekeyster E | 2014 | Invest Ophthalmol Vis Sci2014，55，3： | 1 |
| 3 | MMPs in the trabecu- lar meshwork : promising targets for future glaucoma therapies显示文摘 | De Groef L Van Hove I Dekeyster E | 2013 | Invest Ophthalmol Vis Sci2013，54，12： | 1 |
| 4 | Perchlorate versus other environmental sodium/iodide symporter inhibitors:potential thyroid-related health effects显示文摘 | De Groef B Decallonne BR Van der Geyten S | | 0，，： | 1 |
| 5 | Deficiency of the transcription factor PLAG1 results in aberrant coiling and morphology of the epididymis显示文摘Mice deficient in the transcription factor pleomorphic adenoma gene 1(PLAG1)exhibit reproductive issues that are characterized,in part,by decreased progressive sperm motility in the male.However,the underlying cause of this impairment is unknown.As epididymal transit is critical for sperm maturation and motility,the morphology of the epididymis of Plag1-deficient mice was investigated and the spatial expression patterns of PLAG1 protein and mRNA were identified.Using X-gal staining and in situ hybridization,PLAG1 was shown to be widely expressed in both the epithelium and stroma in all regions of the mouse epididymis.Interestingly,the X-gal staining pattern was markedly different in the cauda,where it could be suggestive of PLAG1 secretion into the epididymal lumen.At all ages investigated,the morphology of epididymides from Plag1 knockout(KO)mice was aberrant;the tubule failed to elongate and coil,particularly in the corpus and cauda,and the cauda was malformed,lacking its usual bulbous shape.Moreover,the epididymides from Plag1 KO mice were significantly reduced in size relative to body weight.In 20%of Plag1-deficient mice,the left testicle and epididymis were lacking.The impaired morphogenesis of the epididymal tubule is likely to be a major contributing factor to the fertility problems observed in male Plag1-deficient mice.These results also establish PLAG1 as an important regulator of male reproduction,not only through its involvement in testicular sperm production,but also via its role in the development and function of the epididymis. | Joanne Wong Almas R Juma Stephanie C Tran Jemma G Gasperoni Sylvia V H Grommen Bert De Groef | 2020 | Asian Journal of Andrology2020，22，4： | 1 |
| 6 | Role of corticotropin-releasing hormone as a thyrotropin-releasing factor in non-mammalian vertebrates 显示文摘 | De Groef B Van der Geyten S Darras V M | 2006 | General and Comparative Endocrinology2006，146，1： | 1 |
| 7 | Perchlo- rate Versus Other Environmental Sodium/ Iodide Symporter Inhibitors: Potential Thyroid - related Health Effects 显示文摘 | Groef B D Decallonne B R Van der Geyten S | 2006 | European Journal of Endo- crinology2006，155，： | 1 |
| 8 | Perchlorate versus other environmental sodium/iodide sym- porter inhibitors: potential thyroid-related health effects显示文摘 | Bert De Groef Brigitte R Decallonne Serge Van der Geyten | 2006 | European Journal of Endocrinology2006，155，： | 1 |
| 9 | Reaching for the brain:stimulating neural activity as the big leap in optic nerve regeneration显示文摘In the August issue of Nature Neuroscience,Lim and coworkers reported on their study of axonal regeneration in the adult optic nerve,revealing that combined activation of mammalian target of rapamycin(mTOR)signaling and enhancing neural activity leads to successful | Emiel Geeraerts Lieve Moons Lies De Groef | 2016 | Eye Science2016，31，4： | 0 |
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