维普中文期刊产品整合服务
112篇 您的检索式:作者名="Grogan P"
    题名 作者 年代 出处 被引量
1被激光损伤软骨释放的凋亡因子诱导软骨细胞凋亡的研究显示文摘目的探讨组织损伤后凋亡信号怎样促进细胞的死亡进程。方法在激光照射后猪软骨块置培液中,在不同时间(3、6、9、12、24 h)收集的培液,即实验条件培养液(TCM),从未经激光照射的软骨块培液取得的为对照条件培养液(CCM)。软骨块继续培养28 d,用聚焦显微镜评价其受损区的进展。分离的软骨细胞单层放于 TCM、CCM 或正常培养液(NM)培养,阳性对照组单层细胞经紫外线照射10 min 后继续用正常培养液培养,培养24 h 后,收集细胞并用荧光标记物染色,经流式细胞仪分析。结果所有经 TCM 培养的细胞显现半胱氨酸蛋白水解酶(caspase)-3阳性、CMXRos 和一氧化氮信号减少或失去;经 CCM 或 NM 培养的细胞显现 caspase-3阴性、CMXRos 和一氧化氮信号完好;阳性对照组细胞显现 Caspase-3和 CMXRos 均阳性、一氧化氮信号减少或失去,代表处于凋亡早期的细胞。不同 TCM 浓度(100%、50%、25%、12.5%)和时间(0.5、1、3、9、12 h)对细胞作用后,所有细胞均呈现 caspase-3阳性、CMXRos 和一氧化氮信号减少或失去。结论激光照射受损软骨释放凋亡因子,可诱导单层细胞死亡。郑敏 Grogan SP Schaffner T Mainil-Varlet P 2007中华医学杂志2007,87,21:3
2Fire effects on ecosystem nitrogen cycling in a Californian bishop pine forest显示文摘Grogan P Bruns T D Chapin III F S 2000Oecologia2000,122,:1
3Deepened snow al- ters soil microbial nutrient limitations in arctic birch hummock tundra 显示文摘BUCKERIDGE K M GROGAN P 2008Applied Soil Ecology2008,39,2:1
4Recognition of Schistosoma mansoni cathepsins B and by human lgG1 and lgG4 antibodies显示文摘Grogan J Rotmans P Ghoneim H 1997Parasite Immunol1997,19,5:1
5Freeze thaw regime effects on carbon and nitrogen dynamics in sub-arctic heath tundra mesocosms显示文摘I Grogan P Michelsen A Ambus P 2004Soil Biol Bioch2004,,36:1
6Deepened snow increases late thaw biogeochemical pulses in mesic low arctic tundra显示文摘Buckeridge K M Grogan P 2010Biogeochemistry2010,101,13:1
7Soil carbon accumulation during temperate forest succession on abandoned low productivity agricultural lands显示文摘Foote RL Grogan P 2010Ecosystems2010,13,6:1
8CO2 flux measurement using soda lime: Correction for water formed during CO2 adsorption显示文摘Grogan P 1998Ecology1998,79,4:1
9Soil microbial biomass, nutrient availability and nitrogen mineralization potential among vegetation-types in a low arctic tundra landscape显示文摘Chu H Grogan P 2010Plant and soil2010,329,12:1
10Prognostic signficance of the Ki-67-assiciated proliferative antigen in aggressive non-Hodgkin's lymphomas:a prospective southwest oncology group trial显示文摘Miller T P Grogan T M Dahiberg S 1994Blood1994,83,6:1
11Articular cartilage repair using a tissue - engineered cartilage - like implant: an animal study 显示文摘Mainil-Varlet P Grogan S Rieser F 2001Osteoarthritis Cartilage2001,,:1
12Recognition of Schistosoma mansoni cathepsins B and L by human IgG1 and IgG4 antibodies 显示文摘Grogan J Rotmans P Ghoneim H 1997Parasite Immunol1997,9,5:1
13Deeper snow enhances winter respiration from both plant-associated and bulk soil carbon pools in Birch Hummock tundra显示文摘Nobrega S Grogan P 0,,03:1
14Suppression of natural killer cell activity in biliary obstruction显示文摘Lane DR Joshi P Grogan JB 1996Am Surg1996,62,:1
15DNA topoisomerase II expression and the response to primary chemothereph in breast cancer显示文摘Mac Grogan G Rudolph P Mascarel IdI 2003Br J Cancer2003,89,4:1
16MicroRNA-140 is expressed in dif- ferentiated human articular chondrocytes and modulates interleukin-1 responses显示文摘Miyaki S Nakasa T Otsuki S Grogan S P Higashiya- ma R Inoue A 2009Arthritis Rheum2009,60,:1
17Freeze-thaw regime effects on carbon and nitrogen dynamics in sub-arctic heath tun- dra mesocosms 显示文摘Grogan P Michelsen A Ambus P 2004Soil Biology and Biochemistry2004,36,4:1
18Use of allograft bone for posterior spinal fusion in idiopathic scoliosis 显示文摘GROGAN D P KALEN V ROSS T I 1999Clin Orthop Relat Res1999,369,:1
19Validation of a questionnaire measuring patient satisfaction with general practitioner services显示文摘Grogan S Conner M Norman P 2000Qual Health Care2000,9,4:1
20Freeze-thaw regime effects on carbon and nitrogen dynamics in sub-arctic heath tundra mesocosms显示文摘Grogan P Michelsen A Ambus P 2004Soil Biology&Biochemistry2004,36,3:1
返回顶部 每页显示:
共6页 首页 上一页 第1页 下一页 末页 /6 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费