4篇
您的检索式：作者名="Guangkui Xu"
|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Association between Virulence Factors and TRAF1/4-1BB/Bcl-xL Expression in Gastric Mucosa Infected with Helicobacter pylori显示文摘 | Fen Wang Xiang Wu Zhiying Liu Guangkui Bu Xiayu Li Nanfang Qu Jin Peng Canxia Xu Shourong Shen Yi Yuan Michel Kahaleh | 2015 | Gastroenterology Research and Practice2015，，： | 1 |
| 2 | Self-assembly of lipids and nanoparticles in aqueous solution:Self-consistent field simulations显示文摘Self-assembled nanostructures of lipids and nanoparticles hold great promise for applications in such fields as nanomedicine.This paper uses the self-consistent field theory to investigate the self-assembly behavior of lipid molecules and nanoparticles with different shapes in an aqueous solution.It is found that the lipid molecules can form monolayered and bilayered nanostructures around the nanoparticles with different shapes(e.g.,triangular,square,hexagonal and octangular). With decreasing the size of nanoparticles or increasing the number of polygon edges,the shape of lipid layers will approach an approximately spherical shape.These findings may help to predict and design novel drug delivery nanocarriers. | Weihua Xie Guangkui Xu Xiqiao Feng | 2012 | Theoretical & Applied Mechanics Letters2012，2，1： | 1 |
| 3 | Erratum to“3D collagen matrices modulate the transcriptional trajectory of bone marrow hematopoietic progenitors into macrophage lineage commitment”[Bioact.Mater.10C(April 2022)255-268]显示文摘The publisher regrets the omission of the below footnote for the author Dr.Nu Zhang.The publisher would like to apologise for any inconvenience caused. | Pan Zhang Linmu Xu Jingsong Gao Guangkui Xu Yanping Song Guang Li Jingjing Ren Yunjie Zhang Cheng Yang Yu Zhang Ruiheng Xie Nu Zhang Hui Yang | 2023 | Bioactive Materials2023，，4： | 1 |
| 4 | 3D collagen matrices modulate the transcriptional trajectory of bone marrow hematopoietic progenitors into macrophage lineage commitment显示文摘Physical signals provided by the extracellular matrix(ECM)are key microenvironmental parameters for the fate decision of hematopoietic stem and progenitor cells(HSPC)in bone marrow.Insights into cell-ECM interactions are critical for advancing HSC-based tissue engineering.Herein,we employed collagen hydrogels and collagen-alginate hydrogels of defined stiffness to study the behaviors of hematopoietic progenitor cells(HPCs).Three-dimensional(3D)collagen hydrogels with a stiffness of 45 Pa were found to promote HPC maintenance and colony formation of monocyte/macrophage progenitors.Using single-cell RNA sequencing(scRNA-seq),we also characterized the comprehensive transcriptional profiles of cells randomly selected from two-dimensional(2D)and 3D hydrogels.A distinct maturation trajectory from HPCs into macrophages within the 3D microenvironment was revealed by these results.3D-derived macrophages expressed high levels of various cytokines and chemokines,such as Saa3,Cxcl2,Socs3 and Tnf.Furthermore,enhanced communication between 3D-macrophages and other hematopoietic clusters based on ligand-repair interactions was demonstrated through bioinformatic analyses.Our research underlines the regulatory role of matrix-dimensionality in HPC differentiation and therefore probably be applied to the generation of specialized macrophages. | Pan Zhang Linmu Xu Jingsong Gao Guangkui Xu Yanping Song Guang Li Jingjing Ren Yunjie Zhang Cheng Yang Yu Zhang Ruiheng Xie Nu Zhang Hui Yang | 2022 | Bioactive Materials2022，7，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员