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| 1 | Recombinant CC16 protein inhibits the production of pro-inflammatory cytokines via NF-KB and p38 MAPK pathways in LPS-activated RAW264,7 macrophages显示文摘积累的证据显示克莱拉房间 protein-16 (CC16 ) 有反煽动性的功能,尽管深奥分子的小径完全没被阐明。这里,我们评估了效果肿瘤坏死因素 alpha (TNF-) 的表示上的 recombinant 老鼠 CC16 (rCC16 ) , interleukin-6 (IL-6 ) ,和在 lipopolysaccharide (LPS ) 的 IL-8 刺激了老鼠巨噬细胞(RAW264.7 房间) 并且探索了内在的分子的机制。rCC16 在两个禁止了导致 LPS 的 TNF- , IL-6,和 IL-8 表示,这被发现送信人 ribonucleicacid (mRNA ) 水平和蛋白质以一种集中依赖者方式铺平,由即时反向的 transcriptase 聚合酶链反应和连接酶的 immunosorbent 试金示威了。如此的镇压效果被 transcriptional 活动和原子因素(NF ) 的脱氧核糖核酸酸绑定活动的抑制伴随 -B 然而并非使活跃之物蛋白质(AP )-1。西方的污点分析进一步表明 rCC16 禁止了原子 NF-B 和 NF-B 禁止的蛋白质 IB,和 p38 的 cytosolic NF-B, phosphorylation 和减小的减小的增加激活 mitogen 的蛋白质 kinase (MAPK ) 依赖者由在它的 p65 子单元的 Ser276 的 phosphorylation 的 NF-B 激活。而且, rCC16 被发现没另外在c6月N终端 kinase ,c6月,或c-Jun.的原子 translocation 的 phosphorylation 上有效果,TNF-的减小, IL-6 ,并且 IL-8 被颠倒内长的uteroglobin有约束力的蛋白质的水平什么时候被 RNA 干扰在 对待rCC16 、 对待LPS 的 RAW264.7 房间减少。我们的数据建议 rCC16 由在 RAW264.7 房间使 NF-B 和 p38 MAPK 然而并非 AP-1 失去活性压制调停 LPS 的煽动性的调停人 TNF- , IL-6,和 IL-8 生产。 | Min Pang Yangyang Yuan Dong Wang Ting Li Dan Wang Xiaohong Shi Min Guo Chunfang Wang Xinri Zhang Guoping Zheng Baofeng Yu Hailong Wang | 2017 | Acta Biochimica et Biophysica Sinica2017，49，5： | 14 |
| 2 | Data-Based Predictive Control for Networked Nonlinear Systems with Packet Dropout and Measurement Noise显示文摘In this paper, the data-based control problem is investigated for a class of networked nonlinear systems with measurement noise as well as packet dropouts in the feedback and forward channels. The measurement noise and the number of consecutive packet dropouts in both channels are assumed to be random but bounded. A data-based networked predictive control method is proposed, in which a sequence of control increment predictions are calculated in the controller based on the measured output error, and based on the control increment predictions received by the actuator, a proper control action is obtained and applied to the plant according to the real-time number of consecutive packet dropouts at each sampling instant. Then the stability analysis is performed for the networked closedloop system. Finally, the effectiveness of the proposed method is illustrated by a numerical example. | PANG Zhonghua LIU Guoping ZHOU Donghua SUN Dehui | 2017 | Journal of Systems Science & Complexity2017，30，5： | 12 |
| 3 | A delayed stage-structured predator- prey model with impulsive stocking on prey and continuous harvesting on predator显示文摘 | JIAO Jianjun PANG Guoping CHEN Lansun LUO Guilie | 2008 | Applied Mathematics and Computation2008，195，1： | 1 |
| 4 | A Novel Networked Predictive Control Method for Systems with Random Communication Constraints显示文摘This paper presents a novel observer-based predictive control method for networked systems where random network-induced delays,packet disorders and packet dropouts in both feedback and forward channels are considered.The proposed method has three significant features:i)A concept of destination-based lumped(DBL)delay is introduced to represent the combined effects of random communication constraints in each channel;ii)in view of different natures of the random DBL delays in the feedback and forward channels,different compensation schemes are designed;and iii)it is actual control inputs rather than predicted ones that are employed to generate future control signals based on the latest system state estimate available in the controller.For the resulting closed-loop system,a necessary and sufficient stability condition is derived,which is less conservative and also independent of random communication constraints in both channels.Simulation results are provided to demonstrate the effectiveness of the proposed method. | PANG Zhonghua BAI Chuandong LIU Guoping HAN Qinglong ZHANG Xianming | 2021 | Journal of Systems Science & Complexity2021，34，4： | 1 |
| 5 | A delayed SIRS epidemic model with pulse vaccination 显示文摘 | Pang Guoping Chen Lansun | 2007 | Science Direct Chaos Solitons and Fractal2007，34，： | 1 |
| 6 | A delayed stage-structured predator-prey model with impulsive stocking on prey and continuous harvesting on predator显示文摘 | JIAO Jianjun PANG Guoping CHEN Lansun | 2008 | Appl Math and Comput2008，195，1： | 1 |
| 7 | A delayed SIRS epidemic model with pulse vaccination 显示文摘 | Pang Guoping Chen Lansun | 2007 | Chaos Solitons & Fractals2007，34，5： | 1 |
| 8 | A delayed stage-structured predator-prey model with im- pulsive stocking on prey and continuous harvesting on predator显示文摘 | Jiao Jianjun Pang Guoping Chen Lansun | 2008 | Applied Mathematics and Computation2008，195，1： | 1 |
| 9 | A delayed stage-structured predator-prey model with impulsive stocking on prey and continuous harvesting on predator显示文摘 | Jiao Jianjun Pang Guoping Chen Lansun | 2008 | Applied Mathematics and Computation2008，195，1： | 1 |
| 10 | The global stabili- ty of a delayed predator-prey system with two stage- structure显示文摘 | WANG Fengyan PANG Guoping | 2009 | Chaos Solitons and Fractals2009，40，2： | 1 |
| 11 | The global stability of a delayed predator–prey system with two stage-structure显示文摘 | Fengyan Wang Guoping Pang | 2007 | Chaos Solitons and Fractals2007，，2： | 1 |
| 12 | A delayed SIRS epidemic model with pulse vaccination 显示文摘 | PANG Guoping CHEN Lansun | 2007 | Chaos Solitons and Fractals2007，34，5： | 1 |
| 13 | A delayed stage-structured predatorprey model with impulsive stocking on prey and continuous harvesting on predator显示文摘 | JIAO Jianjun PANG Guoping CHEN Lansun LUO Guilie | | 0，，01： | 1 |
| 14 | A delayed stage-structured predator-prey model with impulsive stocking on prey and continuous harvesting on predator显示文摘 | Jiao Jianjun Pang Guoping Chen Lansun Luo Guilie | 2008 | Applied Mathematics and Computation2008，195，1： | 1 |
| 15 | A delayed stage-structured predator-prey model with impulsive stocking on prey and continuous harvesting on predator 显示文摘 | Jiao Jianjun Pang Guoping Chen Lansun | 2008 | Applied Mathematics and Computation2008，195，1： | 1 |
| 16 | ER stress induced by ionising radiation in IEC-6 cells显示文摘 | Bo Zhang Yan Wang Xueli Pang Yongping Su Guoping Ai Tao Wang | 2010 | International Journal of Radiation Biology2010，，6： | 1 |
| 17 | A delayed stage-structured predator–prey model with impulsive stocking on prey and continuous harvesting on predator显示文摘 | Jianjun Jiao Guoping Pang Lansun Chen Guilie Luo | 2007 | Applied Mathematics and Computation2007，，1： | 1 |
| 18 | A delayed SIRS epidemic model with pulse vaccination显示文摘 | Pang Guoping ChenLansun | 2007 | Science Direct Chaos Solitons andFractals2007，34，： | 1 |
| 19 | Chaos and Hopf bifurcation of a hybrid ratio-dependent three species food chain显示文摘 | Wang Fengyan Pang Guoping | 2008 | Chaos Solitons and Fractals2008，36，： | 1 |
| 20 | Impulsive state feedback control during the sulphitation reaction in process of manufacture of sugar显示文摘In this paper,the system with impulsive state feedback control corresponding to the sulphitation reaction in process of manufacturo of sugar is considered.By means of square approximation and a series of switched systems,the periodic solution is approximated by a series of continuous hybrid limit cycles.Similar to the analysis of limit cycles of continuous systems,the existence and stability criteria of the order-1 periodic solution are obtained.Further,numerical analysis and discussion are given. | Guoping Pang Xianbo Sun Zhiqing Liang Silian He Xiaping Zeng | 2020 | International Journal of Biomathematics2020，13，8： | 0 |
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