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| 1 | Clinical significance of loss of heterozygosity for M6P/IGF2R in patients with primary hepatocellular carcinoma显示文摘AIM:To investigate the relationship between loss of heterozygosity (LOH) for mannose 6-phosphate/insulin- like growth factor 2 receptor (M6P/IGF2R) and the outcomes for primary HCC patients treated with partial hepatectomy. METHODS: The LOH for M6P/IGF2R in primary HCC patients was assessed using six different gene-specific nucleotide polymorphisms. The patients studied were enrolled to undergo partial hepatectomy. RESULTS: M6P/IGF2R was found to be polymorphic in 73.3% (22/30) of the patients, and of these patients, 50.0% (11/22) had tumors showing LOH in M6P/IGF2R. Loss of heterozygosity in M6P/IGF2R was associated with significant reductions in the two year overall survival rate (24.9% vs 65.5%; P = 0.04) and the disease-free survival rate (17.8% vs 59.3%; P = 0.03). CONCLUSION: These results show M6P/IGF2R LOH predicts poor clinical outcomes in surgically resected primary HCC patients. | Hong Seok Jang Ki Mun Kang Byung Ock Choi Gyu Young Chai Soon Chan Hong Woo Song Ha Randy L Jirtle | 2008 | World Journal of Gastroenterology2008,14,9: | 12 |
| 2 | Efficacy of Pegylated Interferon Monotherapy versus Sequential Therapy of Entecavir and Pegylated Interferon in Hepatitis B e Antigen-Positive Hepatitis B Patients: A Randomized, Multicenter, Phase IIIb Open-Label Study (POTENT Study)显示文摘 | Dae Won Jun Sang Bong Ahn Tae Yeob Kim Joo Hyun Sohn Sang Gyune Kim Se Whan Lee Byung Ho Kim Dong Joon Kim Ja Kyung Kim Hyoung Su Kim Seong Gyu Hwang Won Choong Choi Won Young Tak Heon Ju Lee Ki Tae Yoon Byung Cheol Yun Sung Wook Lee Soon Koo Baik Seung Ha Park Ji Won Park Sol Ji Park Ji Sung Lee | 2018 | Chinese Medical Journal2018,,14: | 5 |
| 3 | Metastasis of hepatocellular carcinoma to the small bowel manifested by intussusception显示文摘肝细胞癌(HCC ) 是造血地并且 lymphogenously 转移到远地点的一个高度侵略的肿瘤。经常的地点是肺,地区性的淋巴节点,骨头,和肾上腺。但是转移到胃肠(官方补给) 道稀罕、很普通地点胃。到小肠的转移是极其稀罕的。而且,引起摄取的小肠的变形 HCC 没被报导直到现在。这里,我们向摄取表明的小肠汇报 HCC 的转移的一个案例。 | Hyun Soo Kim Jung WooShin In Du Jeong Sung-Jo Bang Do Ha Kim Neung Hwa Park Gyu Yeol Kim Young Min Kim Hee Jeong Cha Yoong Ki Jeong | 2006 | World Journal of Gastroenterology2006,12,12: | 2 |
| 4 | Proto-oncogenic H-Ras, K-Ras, and N-Ras are involved in muscle differentiation via phosphatidylinositol 3-kinase显示文摘Oncogenic H 地岬 G12V 和它的变体被显示了禁止肌肉区别。然而,在肌肉区别的 proto-oncogenic 地岬(c 地岬) 的角色仍然保持不清楚。地岬的活跃 GTP 固定的形式包括 Raf, phosphatidylinositol 3-kinase (PI3K ) , Ral-GDS,和播送下游的信号的另外的分子与多样的受动器为伙伴所知。我们假设那 c 地岬可以由有选择地激活 PI3K 刺激肌肉区别,为肌肉区别的一个重要调停人。在我们的实验,由 farnesyltransferase 禁止者和 H 地岬(地岬 S17N ) 的一种主导的否定形式的 c 地岬的抑制压制了肌肉区别。一致地,由 siRNAs 的 H 地岬, K 地岬,和 N 地岬击倒的个人都堵住了肌肉区别。有趣地,我们发现 c 地岬优先地与 PI3K 而非它的主要有约束力的搭挡 c-Raf 交往,在 myogenic 区别期间,与全部的 c 地岬活动仍然保持未改变。PI3K 和它的下游的 myogenic 小径, Nox2/NF-魏 B /inducible 氮的氧化物 synthase (iNOS ) 小径,被发现被 c 地岬活动的抑制在区别期间压制。而且, PI3K 的一种组成地活跃的形式的表示完全救了区别块并且在 c-Ras-inhibited 房间重新激活 Nox2/NF-魏 B /iNOS 小径。根据我们的结果,我们断定与 oncogenic 地岬相反, proto-oncogenic H 地岬, K 地岬,和 N 地岬直接经由 PI3K 和它的下游的发信号小径涉及肌肉区别的提升。另外, PI3K 小径激活与不同主要激活的 Raf/Mek/Erk 小径的并发的抑制被联系。 | Jisun Lee Kyu Jin Choi Min Jin Lim Feng Hong Tae Gyu Choi Eunyoung Tak Seonmin Lee Young-Joo Kim Sung Goo Chang Jin Man Cho Joohun Ha Sung Soo Kim | 2010 | Cell Research2010,20,8: | 2 |
| 5 | Sm 3+ -doped CaTiO 3 phosphor: Synthesis, structure, and photoluminescent properties显示文摘 | Myoung Gyu Ha Mi Rang Byeon Tae Eun Hong Jong Seong Bae Yangsoo Kim S. Park Ho-Soon Yang K.S. Hong | 2011 | Ceramics International2011,,2: | 1 |
| 6 | Expanded indication criteria of living donor liver transplantation for hepatocellular carcinoma at one large‐volume center显示文摘 | Sung‐Gyu Lee Shin Hwang Deok‐Bog Moon Chul‐Soo Ahn Ki‐Hun Kim Kyu‐Bo Sung Gi‐Young Ko Kwang‐Min Park Tae‐Yong Ha Gi‐Won Song | 2008 | Liver Transpl2008,,7: | 1 |
| 7 | Antithrombogenicity of lumbrokinase-immobilized polyurethane显示文摘 | GYU HA RYU SEONYANG PARK MIRAN KIM | 1994 | Journal of Biomedical Materials Research1994,28,: | 1 |
| 8 | The role of endoscopic retrograde cholangiography for biliary stricture after adult living donor liver transplantation: Technical aspect and outcome显示文摘 | Tae Hyup Kim Sung Koo Lee Jung Hye Han Do Hyun Park Sang Soo Lee Dong Wan Seo Myung-Hwan Kim Gi-Won Song Tae-Yong Ha Ki-Hun Kim Shin Hwang Sung Gyu Lee | 2011 | Scandinavian Journal of Gastroenterology2011,,2: | 1 |
| 9 | Long‐term incidence, risk factors, and management of biliary complications after adult living donor liver transplantation显示文摘 | Shin Hwang Sung‐Gyu Lee Kyu‐Bo Sung Kwang‐Min Park Ki‐Hun Kim Chul‐Soo Ahn Young‐Joo Lee Sung‐Koo Lee Gyu‐Sam Hwang Deok‐Bog Moon Tae‐Yong Ha Dong‐Sik Kim Jae‐Pil Jung Gi‐Won Song | 2006 | Liver Transpl2006,,5: | 1 |
| 10 | 显示文摘 | Ha Myoung Gyu Jeong Jaesun Han Kyoung Rim | 2012 | Ceramics International2012,38,: | 1 |
| 11 | Surgical treatment of hilar cholangiocarcinoma in the new era: the Asan experience显示文摘 | Sung Gyu Lee Gi Won Song Shin Hwang Tae Yong Ha Deok Bog Moon Dong Hwan Jung Ki Hun Kim Chul Soo Ahn Myung Hwan Kim Sung Koo Lee Kyu Bo Sung Gi Young Ko | 2010 | Journal of Hepato-Biliary-Pancreatic Sciences2010,,: | 1 |
| 12 | The role of endoscopic retrograde cholangiography for biliary stricture after adult living donor liver transplantation: Technical aspect and outcome显示文摘 | Tae Hyup Kim Sung Koo Lee Jung Hye Han Do Hyun Park Sang Soo Lee Dong Wan Seo Myung-Hwan Kim Gi-Won Song Tae-Yong Ha Ki-Hun Kim Shin Hwang Sung Gyu Lee | 2011 | Scandinavian Journal of Gastroenterology2011,,2: | 1 |
| 13 | Analysis of Torque Ripple in BLDC Motor with Commutation Time显示文摘 | Byoung - Hee Kang Choel - Ju Kim Hyung - Su Mok Gyu - Ha Choe | 2001 | Proceedings of TEEE International Symposium On Industrial Electronics2001,,: | 1 |
| 14 | Angiogra phic characteristics of central neurocytoma suggest the origin of tumor显示文摘 | Sun Ha Paek Jeong Eun Kim Dong Gyu Kim | 2003 | J Korean Med Science2003,18,4: | 1 |
| 15 | Thromboxane A2 synthetase inhibitor plus low dose aspirin: can it be a salvage treatment in acute stroke beyond thrombolytic time window 显示文摘 | Gyu HA Sook YS Cheol S J | 2011 | J Korean Neurosurg S2011,50,1: | 1 |
| 16 | Gamma Knife stereotactic radiosurgery for intracranial hemangiopericytomas显示文摘 | Jin Wook Kim Dong Gyu Kim Hyun-Tai Chung Sun Ha Paek Yong Hwy Kim Jung Ho Han Chul-Kee Park Chae-Yong Kim Hee-Won Jung | 2010 | Journal of Neuro-Oncology2010,,1: | 1 |
| 17 | Min Sub Lee and Jong-Chul Park Plasma surface modification of poly (D,L-lactic-co-glycolic acid)(65/35) film for tissue engineering显示文摘 | Gyu Ha Ryu Won-Sun Yang Hye-Won Roh In-Seop Lee,Jeong Koo Kim,Gun Hwan Lee,Dong Hee Lee,Bong Joo Park | | 0,,: | 1 |
| 18 | Effects of acupuncture stimulation on brain activation induced by cue-elicited alcohol craving显示文摘Acupuncture has been shown to be effective on alcohol use disorder.However,the underlying mechanism remains poorly understood.To investigate the effects of Shenmen(HT7)acupoint on brain activation induced by cue-elicited alcohol craving,30 right-handed healthy light to moderate alcohol drinkers were recruited from the community.They were randomly assigned to undergo acupuncture either at HT7(experimental acupoint,n=15)or Jingqu(LU8,control acupoint,n=15)acupoints.This randomized controlled study was performed in Daegu Haany University and Daegu-Gyeongbuk Medical Innovation Foundation,Republic of Korea.Recruitment and data collection were conducted from December 2018 to May 2019.The results showed that after acupuncture at HT7 acupoint,the activation of orbitofrontal cortex and dorsolateral prefrontal cortex was greatly increased,while the activation of dorsolateral prefrontal cortex was obviously reduced,and subject's craving for alcohol was reduced when he/she seeing alcohol-related video clips involving various alcohols(beer,wine,or soju)or drinking scenarios.Acupuncture at HT7 more greatly reduced subject's alcohol cravings than acupuncture at LU8 acupoint.These findings suggest that acupuncture can improve the self-control of mild to moderate social drinkers through the activation of the orbitofrontal cortex and dorsolateral prefrontal cortex,thereby reducing the craving for alcohol.The study protocol was approved by the Institutional Review Board of Daegu Haany University Korean Medicine Hospital,Republic of Korea(approval No.DHUMC-D-18026-PRO-02)on November 30,2018. | Hyeok Gyu Kwon Seong Hun Choi Joon Ho Seo Chae Ha Yang Mi Young Lee | 2022 | Neural Regeneration Research2022,17,5: | 1 |
| 19 | Reconstruction of inferior right hepatic veins in living donor liver transplantation using right liver grafts显示文摘 | Shin Hwang Tae‐Yong Ha Chul‐Soo Ahn Deok‐Bog Moon Ki‐Hun Kim Gi‐Won Song Dong‐Hwan Jung Gil‐Chun Park Jung‐Man Namgoong Sung‐Won Jung Sam‐Youl Yoon Kyu‐Bo Sung Gi‐Young Ko Byungchul Cho Kyoung Won Kim Sung‐Gyu Lee | 2012 | Liver Transpl2012,,2: | 1 |
| 20 | Processing map for the hot working of Ti-8Ta-3Nb显示文摘 | Kyung Won Lee Jae Sam Ban Min Geun Lee Gyu Ha Kim Kyu Zong Cho | 2008 | Journal of Mechanical Science and Technology2008,,5: | 1 |