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| 1 | Assessment of metastatic liver disease in patients with primary extrahepatic tumors by contrast-enhanced sonography versus CT and MRI显示文摘瞄准:与已知的额外的肝的原发性瘤对包括 CT, MRI 和临床 / 组织学的数据的联合标准答案在病人在肝转移的察觉用 SonoVue 评估提高对比的 ultrasonography (CEUS ) 。方法:它是一国际多集中学习,并且有 12 个中心和 125 个病人(64 男性, 61 女性,变老 59+/-11 年) 包含,与 102 个病人一起每协议。原发性瘤是在 35% 表面的颜色,在 27% 的胸,在 17% 胰腺并且其它在 21% 。用 SonoVue 的 CEUS 用西门子 Elegra, Philips HDI 5000 和 Acuson 红杉与一种 low-mechanical-index 技术和对比特定的软件被采用;为至少五分钟的连续扫描。结果:有 SonoVue 的 CEUS 显著地增加了检测的焦点的肝损害对 unenhanced sonography 的数字。在 31.4% 病人,更多的损害在对比改进以后被发现。检测的损害的全部的数字与 CEUS (55 ) 是可比较的,三倍阶段的螺线 CT (61 ) 和有一个肝特定的对比代理人(53 ) 的 MRI。变形疾病的察觉的精确性(即至少一变形损害) 比为 unenhanced sonography (81.4%) 为 CEUS (91.2%) 是显著地更高的并且类似于三倍阶段的螺线 CT (89.2%) 的。在其 CEUS 检查否定的 53 个病人,后续考试 3-6 瞬间以后在 50 个病人(94.4%) 证实了变形损害的缺席。结论:CEUS 被证明在在有已知的额外的肝的原发性瘤的病人的肝转移的察觉可靠并且怀疑肝损害。 | Christoph F Dietrich Wolfgang Kratzer Deike Strobel Etienne Danse Robert Fessl Alfred Bunk Udo Vossas Karlheinz Hauenstein Wilhelm Koch Wolfgang Blank Matthijs Oudkerk Dietbert Hahn Christian Greis | 2006 | World Journal of Gastroenterology2006，12，11： | 39 |
| 2 | Predictive value of multi-detector computed tomography for accurate diagnosis of serous cystadenoma:Radiologic-pathologic correlation显示文摘AIM:To identify multi-detector computed tomography(MDCT) features most predictive of serous cystadenomas(SCAs),correlating with histopathology,and to study the impact of cyst size and MDCT technique on reader performance.METHODS:The MDCT scans of 164 patients with surgically verified pancreatic cystic lesions were reviewed by two readers to study the predictive value of various morphological features for establishing a diagnosis of SCAs.Accuracy in lesion characterization and reader conf idence were correlated with lesion size(≤3cm or≥3cm) and scanning protocols(dedicated vs routine).RESULTS:28/164 cysts(mean size,39 mm;range,8-92mm) were diagnosed as SCA on pathology.The MDCT features predictive of diagnosis of SCA were microcystic appearance(22/28,78.6%),surface lobulations(25/28,89.3%) and central scar(9/28,32.4%).Stepwise logistic regression analysis showed that only microcystic appearance was signifi cant for CT diagnosis of SCA(P=0.0001).The sensitivity,specificity and PPV of central scar and of combined microcystic appearance and lobulations were 32.4%/100%/100% and 68%/100%/100%,respectively.The reader confidence was higher for lesions>3cm(P=0.02) and for MDCT scans performed using thin collimation(1.25-2.5mm) compared to routine 5 mm collimation exams(P>0.05).CONCLUSION:Central scar on MDCT is diagnostic of SCA but is seen in only one third of SCAs.Microcystic morphology is the most significant CT feature in diagnosis of SCA.A combination of microcystic appearance and surface lobulations offers accuracy comparable to central scar with higher sensitivity. | Anjuli A Shah Nisha I Sainani Avinash Kambadakone Ramesh Zarine K Shah Vikram Deshpande Peter F Hahn Dushyant V Sahani | 2009 | World Journal of Gastroenterology2009，15，22： | 11 |
| 3 | Double-balloon-enteroscopy-based endoscopic retrograde cholangiopancreatography in post-surgical patients显示文摘AIM: To evaluate double balloon enteroscopy (DBE) in post-surgical patients to perform endoscopic retrograde cholangiopancreatography (ERCP) and interventions. METHODS: In 37 post-surgical patients, a stepwise approach was performed to reach normal papilla or enteral anastomoses of the biliary tract/pancreas. When conventional endoscopy failed, DBE-based ERCP was performed and standard parameters for DBE, ERCP and interventions were recorded. RESULTS: Push-enteroscopy (overall, 16 procedures) reached enteral anastomoses only in six out of 37 post-surgical patients (16.2%). DBE achieved a high rate of luminal access to the biliary tract in 23 of the remaining 31 patients (74.1%) and to the pancreatic duct (three patients). Among all DBE-based ERCPs (86 procedures), 21/23 patients (91.3%) were successfully treated. Interventions included ostium incision or papillotomy in 6/23 (26%) and 7/23 patients (30.4%), respectively. Biliary endoprosthesis insertion and regular exchange was achieved in 17/23 (73.9%) and 7/23 patients (30.4%), respectively. Furthermore, bile duct stone extraction as well as ostium and papillary dilation were performed in 5/23 (21.7%) and 3/23 patients (13.0%), respectively. Complications during DBE-based procedures were bleeding (1.1%), perforation (2.3%) and pancreatitis (2.3%), and minor complications occurred in up to 19.1%. CONCLUSION: The appropriate use of DBE yields a high rate of luminal access to papilla or enteral anastomoses in more than two-thirds of post-surgical patients, allowing important successful endoscopic therapeutic interventions. | Martin Raithel Harald Dormann Andreas Naegel Frank Boxberger Eckhart G Hahn Markus F Neurath Juergen Maiss | 2011 | World Journal of Gastroenterology2011，17，18： | 9 |
| 4 | Laparoscopic complete mesocolic excision: West meets East显示文摘Complete mesocolic excision is a relatively new concept in western literature. It follows the same concept of total mesorectal excision and units' routinely performing complete mesocolic excisions have good pathological results as well as good improvements in overall survival, disease free survival and local recurrence. And yet unlike total mesorectal excision, uptake in the West has been relatively slow with many units sceptical of the true benefits gained by taking up a more technically challenging and potentially more morbid procedure when there is a paucity of literature to support these claims. This article reviews complete mesocolic excision for colon cancer, attempting to identify the risks and benefits of the technique and particularly looking at the reasons why its uptake has not been universal. It also discusses the similarities of a complete mesocolic excision to a colon resection with a D3 lymphadenectomy as well as the role of a laparoscopic approach to this technique. Considering a D3 lymphadenectomy has been the standard of care for stage Ⅱ and Ⅲ colon cancers in many of our Asian neighbours for over 20 years, combining this data with data on complete mesocolic excision may provide enough evidence to support or refute the need for complete mesocolic excisions. Maybe there might be lessons to be learnt from our colleagues in the east. | Carina F K Chow Seon Hahn Kim | 2014 | World Journal of Gastroenterology2014，20，39： | 6 |
| 5 | Quantitative study of prostate cancer using three dimensional fiber tractography显示文摘AIM:To investigate feasibility of a quantitative study of prostate cancer using three dimensional(3D)fiber tractography.METHODS:In this institutional review board approved retrospective study,24 men with biopsy proven prostate cancer underwent prostate magnetic resonance imaging(MRI)with an endorectal coil on a 1.5 T MRI scanner.Single shot echo-planar diffusion weighted images were acquired with b = 0.600 s/mm^2,six gradient directions.Open-source available software Track Vis and its Diffusion Toolkit were used to generate diffusion tensor imaging(DTI)map and 3D fiber tracts.Multiple 3D spherical regions of interest were drawn over the areas of tumor and healthy prostatic parenchyma to measure tract density,apparent diffusion coefficient(ADC)and fractional anisotropy(FA),which were statistically analyzed.RESULTS:DTI tractography showed rich fiber tract anatomy with tract heterogeneity.Mean tumor region and normal parenchymal tract densities were 2.53 and 3.37 respectively(P < 0.001).In the tumor,mean ADC was 0.0011 × 10^(-3 )mm^2/s vs 0.0014 × 10^(-3) mm^2/s in the normal parenchyma(P < 0.001).The FA values for tumor and normal parenchyma were 0.2047 and 0.2259 respectively(P = 0.3819).CONCLUSION:DTI tractography of the prostate is feasible and depicts congregate fibers within the gland.Tract density may offer new biomarker to distinguish tumor from normal tissue. | Sandeep Hedgire Alexey Tonyushkin Aoife Kilcoyne Jason A Efstathiou Peter F Hahn Mukesh Harisinghani | 2016 | World Journal of Radiology2016，8，4： | 4 |
| 6 | Recurrent Guillain-Barre syndrome: clinical and laboratory features显示文摘 | Grand' Maison F Feasby TE Hahn AF | 1992 | Brain1992，115，： | 1 |
| 7 | Pressure drop caused by abrupt flow area changes in small channels显示文摘 | F F Abdelall G Hahn S M Ghiaasiaan | 2005 | Experimental Thermal and Fluid Science2005，29，： | 1 |
| 8 | Damage and failure behaviour of a woven C/SiC material显示文摘 | Hahn L Ansorge F Brückner-foit A | 1997 | Journal of Materials Science1997，32，： | 1 |
| 9 | A comparison of anti-DNA antibodies from serum and the kidney eluates of NZB x NZW Fl mice显示文摘 | Hahn BH | 1980 | J Clin Lab Immunol1980，9，： | 1 |
| 10 | Host-pathogen in -teraetions: XXXIII A plant protein converts a fungal pathogenesis factor into an elicitor of plant defense responses显示文摘 | Cervone F Hahn M G De Lorenzo G | 1989 | Plant Physiol1989，90，2： | 1 |
| 11 | On the structure effects of bimetallic PtRu electrocatalysts towards methanol oxidation 显示文摘 | DUBAU L HAHN F COUTANCEAU C | 2003 | Journal of Electroanalytical Chemistry2003，，： | 1 |
| 12 | Lumbar spinal osteotomy for kyphosis in ankylosing spondylitis:the significance of the whole body kyphosis angle显示文摘 | Hahn F Leonardi M | 2007 | J Spinal Disord Tech2007，20，2： | 1 |
| 13 | A convenient rapid culture assay for the detection of enteroviruses in clinical samples: comparison with conventional cell culture and RT-PCR 显示文摘 | Terletskaia-Ladwig E Meier S Hahn R Leinmiiller M Schneider F Enders M | 2008 | J Med Microbiol2008，57，8： | 1 |
| 14 | Minimizing the risk of reporting false positives in large-scale RNAi screens显示文摘 | Echeverri C.J Beachy P.A Baum B Boutros M Buchholz F Chanda K K Downward J Ellenberg J Fraser A.G Hacohen N Hahn W.C Jackson A.L Kiger A Linsley P.S Lum L Ma Y Mathey-Prevot B Root D.E Sabatini D.M Taipale J Perrimon N and Bernards R | | 0，，： | 1 |
| 15 | Linear andnonlinear regression techniques for simultaneousand proportional myoelectric control 显示文摘 | Hahne JM Biessmann F Jiang N | 2014 | IEEETransactions on Neural Systems and RehabilitationEngineering2014，22，2： | 1 |
| 16 | Effects of boron concentration upon oxygen precipitation in Cz silicon 显示文摘 | BULLA D A PONCE F A HAHN S | 1987 | J Crystal Growth1987，85，： | 1 |
| 17 | MR lymphangiogaphy for detection of minimal nodal disease in patients with prostate cancer 显示文摘 | HARISIANGI-IANI M G BARENTSZ J O HAHN P F | 2002 | Acad Rradiol2002，9，2： | 1 |
| 18 | Constitutively active calcineurin mediates delayed neuronal death through Fas-ligand expression via activation of NFAT and FKHR transcriptional activities in mouse brain ischemia显示文摘 | Shioda N Hahn F Moriguchi S | 2007 | J Neurochem2007，102，5： | 1 |
| 19 | Development of an equilibrium dialysis technique for quantifying starch-lipid comliex 显示文摘 | Hahn D Hood L F | 1997 | Cereal Chemistry1997，64，： | 1 |
| 20 | An improved method for nonlinear model reduction using balancing of empirical gramians显示文摘 | Hahn J Edgar T F | 2002 | Computers and Chemical Engineering2002，26，10： | 1 |
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