|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Dietary supplementation with Clostridium butyricum improves growth performance of broilers by regulating intestinal microbiota and mucosal epithelial cells显示文摘Clostridium butyricum has been widely considered an antibiotic substitute in recent years.It can promote growth performance,improve the immune response and enhance the intestinal barrier function of the host.In the present study,1-d-old Arbor Acres(AA)broilers were fed C.butyricum(1×109 cfu/kg)for 28 d.The transcriptomic characteristics of epithelial cells of the cecal mucosa were determined by RNA-sequence,and the cecal microbiota composition was explored by 16 S ribosomal RNA gene sequencing.The changes in the intestinal mucosa of broilers were then analyzed by tissue staining.Gene Ontology(GO)annotations identified substance transport and processes and pathways that might participate in intestinal development and cell viability.Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway analysis revealed that the differentially expressed genes are involved in numerous pathways related to amino acid and vitamin metabolism and antioxidant and defensive functions,among others.The relative expression of some genes associated with intestinal barrier function(claudins 2,15,19,and 23,tight junction proteins 1,2,and 3 and mucin 1)was significantly increased in the treatment group(P<0.05 or P<0.01).Moreover,the proportion of Firmicutes was higher in the C.butyricum-treated group,whereas the proportion of Proteobacteria was higher in the control group.At the genus level,the relative abundances of Butyricicoccus and Lactobacillus,among other bacteria,were increased after C.butyricum supplementation.The tissue staining analysis showed that the cecal mucosa of broilers was significantly ameliorated after the addition of C.butyricum(P<0.05 or P<0.01).These results showed that dietary supplementation with C.butyricum can enhance the antioxidant capacity,mucosal barrier function,and stabilize the cecal microbiota,resulting in improving the growth performance. | Laipeng Xu Xiangli Sun Xianhua Wan Keke Li Fuchun Jian Wenting Li Ruirui Jiang Ruili Han Hong Li Xiangtao Kang Yanbin Wang | 2021 | Animal Nutrition2021，，4： | 12 |
| 2 | Advances in fabrication of ceramic corundum abrasives based on sol–gel process显示文摘Corundum abrasives with good chemical stability can be fabricated into various free abrasives and bonded abrasive tools that are widely used in the precision machining of various parts.However,these abrasives cannot satisfy the machining requirements of difficult-to-machine materials with high hardness,high strength,and strong wearing resistance.Although superhard abrasives can machine the above-mentioned materials,their dressing and manufacturing costs are high.By contrast,ceramic corundum abrasives fabricated by sol–gel method is a costeffective product between conventional and superhard abrasives.Ceramic corundum abrasives exhibit self-sharpening and high toughness.In this review,the optimization methods of ceramic corundum abrasive properties are introduced from three aspects:precursor synthesis,particle shaping,and sintering.Firstly,the functional mechanism of seeds and additives on the microstructural and mechanical properties of abrasives is analyzed.Specifically,seeds can reduce the phase transition temperature and improve fracture toughness.The grain size and uniformly dense structure can be controlled by applying an appropriate amount of multicomponent additives.Then,the urgent need of engineering application and machinability of special shape ceramic corundum abrasives is reviewed,and three methods of abrasive shaping are summarized.The micromold replication technique is highly advanced and can be used to prepare functional abrasives.Additionally,the influence of a new sintering method,namely,two-step sintering technique,on the microstructural and mechanical performance of ceramic corundum abrasives is summarized.Finally,the challenge and developmental trend of the optimization of ceramic corundum abrasives are prospected. | Baoteng HUANG Changhe LI Yanbin ZHANG Wenfeng DING Min YANG Yuying YANG Han ZHAI Xuefeng XU Dazhong WANG Sujan DEBNATH Muhammad JAMIL Hao Nan Li Hafiz Muhammad ALI Munish Kumar GUPTA Zafar SAID | 2021 | Chinese Journal of Aeronautics2021，34，6： | 11 |
| 3 | Characterization and pilot scale test of a fluidized bed two-stage gasification process for the production of clean industrial fuel gas from low-rank coal显示文摘To utilize low rank coal efficiently,a fluidized bed two-stage(FBTS)gasification process,mainly consisting of a FB pyrolyzer and a transport FB(TFB)gasifier,has been proposed for the production of clean fuel gas.To verify the feasibility and technical features of this novel gasification technology,a pilot autothermal platform,with a treating capacity of 100 kg/h for coal,was designed and built up.By adopting a kind of lignite from Inner Mongolia,the running state and fuel gas quality were compared systematically under typical operational conditions.The results show that by keeping the reaction temperatures of pyrolyzer and gasifier at around 840C and 1000C,respectively,the corresponding tar content in fuel gas at the outlets of pyrolyzer and gasifier were 1127 mg/Nm3 and 365 mg/Nm3,reaching a high tar removal efficiency.Under the stable operation state,the volume fractions of CO,H2,CH4 and CO2 in fuel gas were 14.4%,8.3%,3.4%and 11.3%,respectively,and the corresponding higher heating value of fuel gas was about 1100 kcal/Nm3.Compared with the tar from pyrolyzer,the heavy oil fraction in tar from gasifier reduced significantly,while the light oil components increased sharply simultaneously,showing significant effect of catalytic reforming by hot char bed on tar removal. | Xi Zeng Fang Wang Zhennan Han Yanlin Sun Yanbin Cui Guangwen Xu | 2018 | Carbon Resources Conversion2018，1，1： | 8 |
| 4 | Highly Efficient Photoelectrocatalytic Reduction of CO2 to Methanol by a p–n Heterojunction CeO2/CuO/Cu Catalyst显示文摘Photoelectrocatalytic reduction of CO2 to fuels has great potential for reducing anthropogenic CO2 emissions and also lessening our dependence on fossil fuel energy.Herein,we report the successful development of a novel photoelectrocatalytic catalyst for the selective reduction of CO2 to methanol,comprising a copper catalyst modified with flower-like cerium oxide nanoparticles(CeO2 NPs)(a n-type semiconductor)and copper oxide nanoparticles(CuO NPs)(a p-type semiconductor).At an applied potential of−1.0 V(vs SCE)under visible light irradiation,the CeO2 NPs/CuO NPs/Cu catalyst yielded methanol at a rate of 3.44μmol cm^−2 h^−1,which was approximately five times higher than that of a CuO NPs/Cu catalyst(0.67μmol cm^−2 h^−1).The carrier concentration increased by^108 times when the flower-like CeO2 NPs were deposited on the CuO NPs/Cu catalyst,due to synergistic transfer of photoexcited electrons from the conduction band of CuO to that of CeO2,which enhanced both photocatalytic and photoelectrocatalytic CO2 reduction on the CeO2 NPs.The facile migration of photoexcited electrons and holes across the p–n heterojunction that formed between the CeO2 and CuO components was thus critical to excellent light-induced CO2 reduction properties of the CeO2 NPs/CuO NPs/Cu catalyst.Results encourage the wider application of composite semiconductor electrodes in carbon dioxide reduction. | Zhengbin Pan Ershuan Han Jingui Zheng Jing Lu Xiaolin Wang Yanbin Yin Geoffrey INWaterhouse Xiuguo Wang Peiqiang Li | 2020 | Nano-Micro Letters2020，12，2： | 3 |
| 5 | Genetically modified CD7-targeting allogeneic CAR-T cell therapy with enhanced efficacy for relapsed/refractory CD7-positive hematological malignancies:a phase I clinical study显示文摘Chimeric antigen receptor(CAR)-T cell therapy against T cell malignancies faces major challenges including fratricide between CAR-T cells and product contamination from the blasts.Allogeneic CAR-T cells,generated from healthy donor T cells,can provide ready-to-use,blast-free therapeutic products,but their application could be complicated by graft-versus-host disease(GvHD)and host rejection.Here we developed healthy donor-derived,CD7-targeting CAR-T cells(RD13-01)with genetic modifications to resist fratricide,GvHD and allogeneic rejection,as well as to potentiate antitumor function.A phase I clinical trial(NCT04538599)was conducted with twelve patients recruited(eleven with T cell leukemia/lymphoma,and one with CD7-expressing acute myeloid leukemia).All patients achieved pre-set end points and eleven proceeded to efficacy evaluation.No dose-limiting toxicity,GvHD,immune effector cell-associated neurotoxicity or severe cytokine release syndrome(grade≥3)were observed.28 days post infusion,81.8%of patients(9/11)showed objective responses and the complete response rate was 63.6%(7/11,including the patient with AML).3 of the responding patients were bridged to allogeneic hematopoietic stem cell transplantation.With a median follow-up of 10.5 months,4 patients remained in complete remission.Cytomegalovirus(CMV)and/or Epstein-Barr virus(EBV)reactivation was observed in several patients,and one died from EBV-associated diffuse large B-cell lymphoma(DLBCL).Expansion of CD7-negative normal T cells was detected post infusion.In summary,we present the first report of a Phase I clinical trial using healthy donor-derived CD7-targeting allogeneic CAR-T cells to treat CD7^(+)hematological malignancies.Our results demonstrated the encouraging safety and efficacy profiles of the RD13-01 allogeneic CAR-T cells for CD7^(+)tumors. | Yongxian Hu Yali Zhou Mingming Zhang Houli Zhao Guoqing Wei Wengang Ge Qu Cui Qitian Mu Gong Chen Lu Han Tingting Guo Jiazhen Cui Xiaoyan Jiang Xiujun Zheng Shuhui Yu Xiaolong Li Xingwang Zhang Mingxi Chen Xiuju Li Ming Gao Kang Wang Cheng Zu Hao Zhang Xiaohong He Yanbin Wang Dongrui Wang Jiangtao Ren He Huang | 2022 | Cell Research2022，32，11： | 2 |
| 6 | Detection of the mo- bile object with camouflage color under dynamic background based on optical flow 显示文摘 | YIN Jianqin HAN Yanbin HOU Wendi | 2011 | Procedia Engineering2011，，15： | 1 |
| 7 | A Convolution-Based System for Malicious URLs Detection显示文摘Since the web service is essential in daily lives,cyber security becomes more and more important in this digital world.Malicious Uniform Resource Locator(URL)is a common and serious threat to cybersecurity.It hosts unsolicited content and lure unsuspecting users to become victim of scams,such as theft of private information,monetary loss,and malware installation.Thus,it is imperative to detect such threats.However,traditional approaches for malicious URLs detection that based on the blacklists are easy to be bypassed and lack the ability to detect newly generated malicious URLs.In this paper,we propose a novel malicious URL detection method based on deep learning model to protect against web attacks.Specifically,we firstly use auto-encoder to represent URLs.Then,the represented URLs will be input into a proposed composite neural network for detection.In order to evaluate the proposed system,we made extensive experiments on HTTP CSIC2010 dataset and a dataset we collected,and the experimental results show the effectiveness of the proposed approach. | Chaochao Luo Shen Su Yanbin Sun Qingji Tan Meng Han Zhihong Tian | 2020 | Computers, Materials & Continua2020，，1： | 1 |
| 8 | Detection of the mobile object with camouflage color based on optical flow显示文摘 | Yin Jianqin Han Yanbin Hou Wendi | 2011 | Procedia Engineering2011，15，： | 1 |
| 9 | Detection of the mobile object with camouflage color under dynamic background based on optical flow显示文摘 | Yin Jianqin Han Yanbin Hou Wendi | 2011 | Procedia Engineering2011，15，： | 1 |
| 10 | erection ot tile mobile object with camouflage color under dynamic background based on optical flow 显示文摘 | Yin Jianqin Han Yanbin Hou Wendi | 2011 | Procedia Engineering2011，15，： | 1 |
| 11 | Concentration Prediction from Chromatographic Spectra via Hidden Information Detector显示文摘 | Li Jinping Han Yanbin Yin Jianqin | 2005 | International Journal of Information Acquisition2005，2，2： | 1 |
| 12 | Research on improved mean shift algorithm based on local distribu- tion in EEG signal classification 显示文摘 | ZHANG Shaobai HAN Yanbin LI Jinping | 2012 | Journal of Artificial Intelligence Research2012，3，3： | 1 |
| 13 | Recent development in electronic structure tuning of graphitic carbon nitride for highly efficient photocatalysis显示文摘The utilization of solar energy to drive energy conversion and simultaneously realize pollutant degradation via pho-tocatalysis is one of most promising strategies to resolve the global energy and environment issues.During the past decade,graphite carbon nitride(g-C3N4)has attracted dramatically growing attention for solar energy conversion due to its excellent physicochemical properties as a photocatalyst.However,its practical application is still impeded by several limitations and short-comings,such as high recombination rate of charge carriers,low visible-light absorption,etc.As an effective solution,the elec-tronic structure tuning of g-C_(3)N_(4)has been widely adopted.In this context,firstly,the paper critically focuses on the different strategies of electronic structure tuning of g-C_(3)N_(4)like vacancy modification,doping,crystallinity modulation and synthesis of a new molecular structure.And the recent progress is reviewed.Finally,the challenges and future trends are summarized. | Chao Li Jie Li Yanbin Huang Jun Liu Mengmeng Ma Kong Liu Chao Zhao Zhijie Wang Shengchun Qu Lei Zhang Haiyan Han Wenshuang Deng Zhanguo Wang | 2022 | Journal of Semiconductors2022，43，2： | 1 |
| 14 | Desulfurizer desulphurization kinetics by the injection method显示文摘To obtain a better desulphurization effect in hot metal, suitable desulfurizers should be selected first according to thermodynamics. However, the effect of desulphurization is also strongly affected by kinetics. The conditions of different desulfurizers (Mg, CaC2, and lime) penetrating into hot metal, the rising up velocity in iron melt, residence time, and dissolving time are theoretically calculated and analyzed. The results are helpful to select the desulphurization process and equipment and to improve the desulphuri-zation effect. | Wei Wu Zhijun Han Yanbin Hu Wei Wu2 | 2008 | Journal of University of Science and Technology Beijing2008，15，4： | 1 |
| 15 | Molecular characterization and expression profiles of cdc2 and cyclin B during oogenesis and spermatogenesis in green mud crab ( Scylla paramamosain )显示文摘 | Kunhuang Han Yanbin Dai Zhihua Zou Mingjun Fu Yilei Wang Ziping Zhang | 2012 | Comparative Biochemistry and Physiology Part B (-)2012，，3： | 1 |
| 16 | Prediction of water consumption in hospitals based on a modified grey GM (0,1 I sin) model of oscillation sequence, The example of wuhan city显示文摘 | Zhou Han Huang Jiejun Yuan Yanbin | 2014 | Journal Of Applied Mathematics2014，，： | 1 |
| 17 | TEMPO and its derivatives mediated reactions under transitionmetal-free conditions显示文摘2,2,6,6-Tetramethyl-l-piperidinyl-N-oxyl(TEMPO)and its derivatives as stable radicals can participate in many reactions.During the process,TEMPO and its derivatives could act not only as the substrates to capture or initiate new radical intermediates to provide new compounds but also as organic catalysts or oxidants for transformations of alkenes,alcohols,aldehydes and so on to synthesize various high valueadded compounds.In this review,we would introduce recent advances of the transformations of different substrates mediated by TEMPO and its derivatives under transition-metal-free conditions. | Hongfeng Zhuang Heng Li Shuai Zhang Yanbin Yin Feng Han Chao Sun Chengxia Miao | 2020 | Chinese Chemical Letters2020，31，1： | 1 |
| 18 | Identifying Honeypots from ICS Devices Using Lightweight Fuzzy Testing显示文摘The security issues of industrial control systems(ICSs)have become increasingly prevalent.As an important part of ICS security,honeypots and anti-honeypots have become the focus of offensive and defensive confrontation.However,research on ICS honeypots still lacks breakthroughs,and it is difficult to simulate real ICS devices perfectly.In this paper,we studied ICS honeypots to identify and address their weaknesses.First,an intelligent honeypot identification framework is proposed,based on which feature data type requirements and feature data acquisition for honeypot identification is studied.Inspired by vulnerability mining,we propose a feature acquisition approach based on lightweight fuzz testing,which utilizes the differences in error handling between the ICS device and the ICS honeypot.By combining the proposed method with common feature acquisition approaches,the integrated feature data can be obtained.The experimental results show that the feature data acquired is effective for honeypot identification. | Yanbin Sun Xiaojun Pan Chao Xu Penggang Sun Quanlong Guan Mohan Li Men Han | 2020 | Computers, Materials & Continua2020，，11： | 0 |
| 19 | Seismic wave equations in tight oil/gas sandstone media显示文摘Tight oil/gas medium is a special porous medium,which plays a significant role in oil and gas exploration.This paper is devoted to the derivation of wave equations in such a media,which take a much simpler form compared to the general equations in the poroelasticity theory and can be employed for parameter inversion from seismic data.We start with the fluid and solid motion equations at a pore scale,and deduce the complete Biot’s equations by applying the volume averaging technique.The underlying assumptions are carefully clarified.Moreover,time dependence of the permeability in tight oil/gas media is discussed based on available results from rock physical experiments.Leveraging the Kozeny-Carman equation,time dependence of the porosity is theoretically investigated.We derive the wave equations in tight oil/gas media based on the complete Biot’s equations under some reasonable assumptions on the media.The derived wave equations have the similar form as the diffusiveviscous wave equations.A comparison of the two sets of wave equations reveals explicit relations between the coefficients in diffusive-viscous wave equations and the measurable parameters for the tight oil/gas media.The derived equations are validated by numerical results.Based on the derived equations,reflection and transmission properties for a single tight interlayer are investigated.The numerical results demonstrate that the reflection and transmission of the seismic waves are affected by the thickness and attenuation of the interlayer,which is of great significance for the exploration of oil and gas. | Jinghuai GAO Weimin HAN Yanbin HE Haixia ZHAO Hui LI Yijie ZHANG Zongben XU | 2021 | Science China Earth Sciences2021，64，3： | 0 |
| 20 | Comparative Study of Overseas Forest Carbon Financing Patterns and Its Inspiration on China显示文摘The role and position of forestry in response to the issue of climate change have been increasingly concerned by more and more countries and the international community.The cost incurred in forest carbon sequestration is lower than other options to mitigate climate change.However,the fund’s gap becomes the main barrier to reducing carbon emissions caused by deforestation and forest degradation(REDD) and enhancing carbon storage in forests(REDD +) and also becomes the concerns of governments,academic community and enterprises.Based on the comparative analysis of overseas forest carbon financing models,the paper pinpointed their development trend and proposed solutions to financing for forest carbon sink in China. | Guo Yanbin Zhang Caihong Guo Enyu Zhu Han | 2012 | Chinese Forestry Science and Technology2012，11，3： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员