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| 1 | 血管紧张素转换酶抑制剂和血管紧张素受体拮抗剂的使用与2019冠状病毒疾病检测阳性之间的关系显示文摘血管紧张素转换酶抑制剂(angiotensin-converting enzyme inhibitor,ACEI)和血管紧张素受体拮抗剂(angiotensin receptor blocker,ARB)在2019新型冠状病毒疾病(coronavirus disease 2019,COVID-19)全球大流行背景下的作用备受争议。此类药物是治疗一些慢性病的必须药物,有建议停止使用这些药物. | Mehta N KalraA Nowacki AS Anjewierden S Han Z Bhat p Rubio AEC Jacob M Procop GW Harrington S Milinovich A Svensson LG Jehi L Young JB Chung MK 周卫(译) 叶鹏(校) | 2020 | 中华高血压杂志2020，28，5： | 9 |
| 2 | Dietary and metabolomic determinants of relapse in ulcerative colitis patients: A pilot prospective cohort study显示文摘AIM To identify demographic, clinical, metabolomic, and lifestyle related predictors of relapse in adult ulcerative colitis(UC) patients.METHODS In this prospective pilot study, UC patients in clinical remission were recruited and followed-up at 12 mo to assess a clinical relapse, or not. At baseline information on demographic and clinical parameters was collected. Serum and urine samples were collected for analysis of metabolomic assays using a combined direct infusion/liquid chromatography tandem mass spectrometry and nuclear magnetic resolution spectroscopy. Stool samples were also collected to measure fecal calprotectin(FCP). Dietary assessment was performed using a validated self-administered food frequency questionnaire. RESULTS Twenty patients were included(mean age: 42.7 ± 14.8 years, females: 55%). Seven patients(35%) experienced a clinical relapse during the follow-up period. While 6 patients(66.7%) with normal body weight developed a clinical relapse, 1 UC patient(9.1%) who was overweight/obese relapsed during the follow-up(P = 0.02). At baseline, poultry intake was significantly higher in patients who were still in remission during follow-up(0.9 oz vs 0.2 oz, P = 0.002). Five patients(71.4%) with FCP > 150 μg/g and 2 patients(15.4%) with normal FCP(≤ 150 μg/g) at baseline relapsed during the follow-up(P = 0.02). Interestingly, baseline urinary and serum metabolomic profiling of UC patients with or without clinical relapse within 12 mo showed a significant difference. The most important metabolites that were responsible for this discrimination were trans-aconitate, cystine and acetamide in urine, and 3-hydroxybutyrate, acetoacetate and acetone in serum. CONCLUSION A combination of baseline dietary intake, fecal calprotectin, and metabolomic factors are associated with risk of UC clinical relapse within 12 mo. | Ammar Hassanzadeh Keshtel iFloris F van den Brand Karen L Madsen Rupasri Mandal Rosica ValchevaKaren I Kroeker Beomsoo Han Rhonda C Bell Janis Cole Thomas Hoevers David S Wishart Richard N Fedorak Levinus A Dieleman | 2017 | World Journal of Gastroenterology2017，23，21： | 9 |
| 3 | 短期常压低氧步行训练对肥胖成年人运动能力和步态的影响显示文摘为了比较以个人喜好的步行速度(preferred walking speed,PWS)短期低氧与常氧训练对肥胖患者的能量、力学、效率和代谢风险标志物的影响,Fernández Menéndez等纳入肥胖患者23例,在缺氧[海拔3km,n=12;体质量指数(body mass index,BMI)(34.0±0.8)kg/m2]或常氧[海拔360m,n=11;BMI(32.9±0.8)kg/m2]情况下. | 刘青 叶鹏 Fernández Menéndez A Saudan G Sperisen L Hans D Saubade M Millet GP Malatesta D | 2018 | 中华高血压杂志2018，26，6： | 2 |
| 4 | Modeling piezoelectric actuators显示文摘 | Willem L | 2000 | IEEE/ASME Transactions on Mechatronics2000，5，4： | 1 |
| 5 | The 9-fluorenylmethoxycarbonyl amino-protecting group显示文摘 | Carpino L A Han G Y | 1972 | J OrgChem1972，37，： | 1 |
| 6 | Estimation of suspended sediment concentration in water using integrated surface reflectance显示文摘 | Mahtaba A L Runquist D C Han L H | 1998 | Geocarto International1998，13，2： | 1 |
| 7 | Distinct mechanisms of TGF-betal-mediated epithelial-to-mesenchymal transition and metastasis during skin carcinogenesis 显示文摘 | Han G Lu S L Li A G | 2005 | J Clin Invest2005，115，7： | 1 |
| 8 | Finite element analysis of Lamb wave propagation in a thin aluminum plate 显示文摘 | Han S J Palazotto A N Leakeas C L | 2009 | Journal of Aerospace Engineering2009，22，2： | 1 |
| 9 | Network model- ing links breast cancer susceptibility and centrosome dysfunc- tion显示文摘 | Pujana M A Han J D J Starita L M | 2007 | Nat Genet2007，39，11： | 1 |
| 10 | B io a v a ila b ility andpopulation pharm acokinetics o f voriconazole in lungtransplant recipien ts 显示文摘 | Han K C apitano B B ies R et a l | 2010 | Antimicrob Agents Chemother2010，54，10： | 1 |
| 11 | Breast cancerfollowing diethylstilbestrol exposure in utero: insights from a tragedy显示文摘 | Hans O A Pagona L Dimitrios T | 2012 | European Journal of Epidemiology2012，27，1： | 1 |
| 12 | AP-I and NF-kappaB regulation in rheumatoid arthritis and murine collagen-induced arthritis 显示文摘 | Han Z Boyle D L Manning A M | 1998 | Autoimmunity1998，28，4： | 1 |
| 13 | miR- 221/222 promote malignant progression of glioma through activat on of the Akt pathway显示文摘 | Zhang J Han L Ge Y Zhou X Zhang A Zhang C | 2010 | Int J Oncol2010，36，： | 1 |
| 14 | Color stability of compomer after immersion in various media 显示文摘 | ABU- BAKR N HAN L OKAMATO A | 2000 | J Esthet Dent2000，，12： | 1 |
| 15 | 8-Hydroxyquinoline benzoates as highly sensitive fluorescent chemosensors for transition metal ions 显示文摘 | Zhang H Han L F Zachariasse K A | 2005 | Org Lett2005，7，19： | 1 |
| 16 | Efficient transformation of Actinidia arguta by reducing the strength of basal salts in the medium to alleviate callus browning显示文摘 | Han M L Gleave A P Wang T C | 2010 | Plant B iotechnology Reporter2010，4，： | 1 |
| 17 | Equivalent threshold sound pressure levels for Sennheiser HDA 200 earphone and etymotic research ER-2 insert earphone in the frequency range 125 Hz to 16 kHz 显示文摘 | HAN L A POULSEN T | 1997 | Scand Audiol1997，22，10： | 1 |
| 18 | Vehicle routing under time-dependent travel times: the impact of congestion avoidance显示文摘 | A L Kok E W Hans J M J Schutten | 2012 | Computers & Operations Research2012，39，5： | 1 |
| 19 | Mierostructural char- acteristics of Au/Al bonded interfaces 显示文摘 | LI J H DUAN J A HAN L | 2007 | Materials Characterization2007，58，： | 1 |
| 20 | Innovative food packaging solutions 显示文摘 | Brody A L Bugusu B Han J H | 2008 | Scientific Status Summary2008，73，8： | 1 |
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