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| 1 | Hesrl and Hesr2 may act as early effectors of Notch signaling in the developing cochlea显示文摘 | Hayashi T Kokubo H Hartman B H | 2008 | Dev Biol2008，316，1： | 1 |
| 2 | Designing efficient systems with the equal marginal performance principle 显示文摘 | HARTMAN T B | 2005 | ASHRAE Journal2005，47，7： | 1 |
| 3 | All variable speed centrifugal chiller plants显示文摘 | HARTMAN T B | 2001 | ASHRAEJ2001，43，9： | 1 |
| 4 | Global optimization strategies for highperformance controls显示文摘 | Hartman T B | 1995 | ASHARE Transactions1995，101，2： | 1 |
| 5 | Designing efficient systems with the equal marginal performance principle显示文摘 | Hartman T B | 2005 | ASHRAE J2005，47，7： | 1 |
| 6 | Real-world cure rates for hepatitis C virus treatments that include simeprevir and/or sofosbuvir are comparable to clinical trial results显示文摘AIM To assess the real-world effectiveness and cost of simeprevir(SMV), and/or sofosbuvir(SOF)-based therapy for chronic hepatitis C virus(HCV) infection.METHODS The real-world performance of patients treated with SMV/SOF ± ribavirin(RBV), SOF/RBV, and SOF/RBV with pegylated-interferon(PEG) were analyzed in a consecutive series of 508 patients with chronic HCV infection treated at a single academic medical center. Patients with genotypes 1 through 4 were included. Rates of sustained virological response-the absence of a detectable serum HCV RNA 12 wk after the end of treatment [sustained virological response(SVR) 12]-were calculated on an intention-to-treat basis. Costs were calculated from the payer's perspective using Medicare/Medicaid fees and Redbook Wholesale Acquisition Costs. Patient-related factors associated with SVR12 were identified using multivariable logistic regression.RESULTS SVR 12 rates were as follows: 86%(95%CI: 80%-91%)among 178 patients on SMV/SOF ± RBV; 62%(95%CI: 55%-68%) among 234 patients on SOF/RBV; and 78%(95%CI: 68%-86%) among 96 patients on SOF/PEG/RBV. Mean costs-per-SVR 12 were $174442(standard deviation: ± $18588) for SMV/SOF ± RBV; $223003(± $77946) for SOF/RBV; and $126496(± $31052) for SOF/PEG/RBV. Among patients on SMV/SOF ± RBV, SVR12 was less likely in patients previously treated with a protease inhibitor [odds ratio(OR): 0.20, 95%CI: 0.06-0.56]. Higher bilirubin(OR: 0.47, 95%CI: 0.30-0.69) reduced the likelihood of SVR12 among patients on SOF/RBV, while FIB-4 score ≥ 3.25 reduced the likelihood of SVR 12(OR: 0.18, 95%CI: 0.05-0.59) among those on SOF/PEG/RBV. CONCLUSION SVR 12 rates for SMV and/or SOF-based regimens in a diverse real-world population are comparable to those in clinical trials. Treatment failure accounts for 27% of costs. | Kian Bichoupan Neeta Tandon James F Crismale Joshua Hartman David Del Bello Neal Patel Sweta Chekuri Alyson Harty Michel Ng Keith M Sigel Meena B Bansal Priya Grewal Charissa Y Chang Jennifer Leong Gene Y Im Lawrence U Liu Joseph A Odin Nancy Bach Scott L Friedman Thomas D Schiano Ponni V Perumalswami Douglas T Dieterich Andrea D Branch | 2017 | World Journal of Virology2017，6，4： | 1 |
| 7 | Impact of oxidative stress on female fertility显示文摘 | Ruder E H Hartman T J Goldman M B | 2009 | Current Opinion in Obstetrics&Gynecology2009，21，3： | 1 |
| 8 | Synthesis,Anti -HIV Activity, and Metabolic Stability of New Alkenyldiarylmethane HIV -1 Non -Nucleoside Reverse Transcriptase Inhibitors 显示文摘 | Deng B L Hartman T L Buckheit R W | 2005 | J Med Chem2005，48，： | 1 |
| 9 | Impact of oxida-tive stress on female fertility显示文摘 | RUDER E H HARTMAN T J GOLDMAN M B | 2009 | Curr Opin Obstet Gynecol2009，21，3： | 1 |
| 10 | Early intragastric feeding of seriously burned and long-term ventilated patients a review of 55 patients显示文摘 | Raff T Hartman B Germann G | 1997 | Burns1997，23，： | 1 |
| 11 | Impact of oxida-tive stress on femal fertility显示文摘 | RUDER E H HARTMAN T J GOLDMAN M B | 2009 | Curr Opin Obstet Gynecol2009，21，3： | 1 |
| 12 | Clear cell renalcell carcinoma with osseous metaplasia: a case report显示文摘 | Hartman R J Helfand B T Dalton D P | 2011 | Can J Urol2011，18，1： | 1 |
| 13 | High-functional-avidity cytotoxic T lymphocyte re- sponses to HLA-B-restricted Gag-derived epitopes as- sociated with relative HIV control 显示文摘 | Berger C T Frahm N Price D A Mothe B Ghebre- michael M Hartman K L Henry L M Brenchley J M Ruff L E Venturi V Pereyra F Sidney J Sette A Douek D C Walker B D Kaufmann D E Brander C | 2011 | J Viral2011，85，18： | 1 |
| 14 | Presence of the mu3 opiate receptor in endothelial cells:Coupling to nitric oxide production and vasodilation显示文摘 | STEFANO G B HARTMAN A BILFINGER T V | 1995 | J Biol Chem1995，270，30： | 1 |
| 15 | Mycobacterium tu- berculosis is extraordinarily sensitive to killing by a vitamin C-in- duced Fenton reaction显示文摘 | Vilcheze C Hartman T Weinirck B | 2013 | Nature Commun2013，，4： | 1 |
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