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| 1 | Efficacy of peroral endoscopic myotomy vs other achalasia treatments in improving esophageal function显示文摘AIM: To assess and compare the esophageal function after peroral endoscopic myotomy(POEM) vs other conventional treatments in achalasia.METHODS: Chart review of all achalasia patients who underwent POEM, laparoscopic Heller myotomy(LHM) or pneumatic dilation(PD) at our institution between January 2012 and March 2015 was performed. Patient demographics, type of achalasia, prior treatments, pre- and post-treatment timed barium swallow(TBE) and high-resolution esophageal manometry(HREM) findings were compared between the three treatment groups. Patients who had both pre- and 2 mo posttreatment TBE or HREM were included in the final analysis. TBE parameters compared were barium column height, width and volume of barium remaining at 1 and 5 min. HREM parameters compared were basal lower esophageal sphincter(LES) pressures and LES-integrated relaxation pressures(IRP). Data are presented as mean ± SD, median [25th, 75 th percentiles] or frequency(percent). Analysis of variance, KruskalWallis test, Pearsons χ~2 test and Fishers Exact tests were used for analysis.RESULTS: A total of 200 achalasia patients were included of which 36 underwent POEM, 22 underwent PD and 142 underwent LHM. POEM patients were older(55.4 ± 16.8 years vs 46.5 ± 15.7 years, P = 0.013) and had higher BMI than LHM(29.1 ± 5.9 kg/m^2 vs 26 ± 5.1 kg/m^2, P = 0.012). More number of patients in POEM and PD groups had undergone prior treatments compared to LHM group(72.2% vs 68.2% vs 44.3% respectively, P = 0.003). At 2 mo post-treatment, all TBE parameters including barium column height, width and volume remaining at 1 and 5 min improved significantly in all three treatment groups(P = 0.01 to P < 0.001) except the column height at 1 min in PD group(P = 0.11). At 2 mo post-treatment, there was significant improvement in basal LES pressure and LES-IRP in both LHM(40.5 mm Hg vs 14.5 mm Hg and 24 mm Hg vs 7.1 mm Hg respectively, P < 0.001) and POEM groups(38.7 mm Hg vs 11.4 mm Hg and 23.6 mm Hg vs 6.6 mm Hg respectively, P < 0.001). However, when the efficacy of three treatments were compared to each other in terms of improvement in TBE or HREM parameters at 2 mo, there was no significant difference(P > 0.05).CONCLUSION: POEM, PD and LHM were all effective in improving esophageal function in achalasia at shortterm. There was no difference in efficacy between the three treatments. | Madhusudhan R Sanaka Umar Hayat Prashanthi N Thota Ramprasad Jegadeesan Monica Ray Scott L Gabbard Neha Wadhwa Rocio Lopez Mark E Baker Sudish Murthy Siva Raja | 2016 | World Journal of Gastroenterology2016，22，20： | 7 |
| 2 | A framework infrageneric classification of Carex (Cyperaceae) and its organizing principles显示文摘Phylogenetic studies of Carex L.(Cyperaceae)have consistently demonstrated that most subgenera and sections are para-or polyphyletic.Yet,taxonomists continue to use subgenera and sections in Carex classification.Why?The Global Carex Group(GCG)here takes the position that the historical and continued use of subgenera and sections serves to(i)organize our understanding of lineages in Carex,(ii)create an identification mechanism to break the~2000 species of Carex into manageable groups and stimulate its study,and(iii)provide a framework to recognize morphologically diagnosable lineages within Carex.Unfortunately,the current understanding of phylogenetic relationships in Carex is not yet sufficient for a global reclassification of the genus within a Linnean infrageneric(sectional)framework.Rather than leaving Carex classification in its current state,which is misleading and confusing,we here take the intermediate steps of implementing the recently revised subgeneric classification and using a combination of informally named clades and formally named sections to reflect the current state of our knowledge.This hybrid classification framework is presented in an order corresponding to a linear arrangement of the clades on a ladderized phylogeny,largely based on the recent phylogenies published by the GCG.It organizes Carex into six subgenera,which are,in turn,subdivided into 62 formally named Linnean sections plus 49 informal groups.This framework will serve as a roadmap for research on Carex phylogeny,enabling further development of a complete reclassification by presenting relevant morphological and geographical information on clades where possible and standardizing the use of formal sectional names. | Eric H.Roalson Pedro Jiménez-Mejías Andrew L.Hipp Carmen Benítez-Benítez Leo P.Bruederle Kyong-Sook Chung Marcial Escudero Bruce A.Ford Kerry Ford Sebastian Gebauer Berit Gehrke Marlene Hahn Muhammad Qasim Hayat Mathias H.Hoffmann Xiao-Feng Jin Sangtae Kim Isabel Larridon Étienne Léveillé-Bourret Yi-Fei Lu Modesto Luceño Enrique Maguilla Jose IgnacioMárquez-Corro Santiago Martín-Bravo Tomomi Masaki Mónica Míguez Robert F.C.Naczi Anton A.Reznicek Daniel Spalink Julian R.Starr Uzma Tamara Villaverde Marcia J.Waterway Karen L.Wilson and Shu-Ren Zhang | 2021 | Journal of Systematics and Evolution2021，59，4： | 3 |
| 3 | Enzyme- linked aptamer assays (ELAAs), based on a competition format for a rapid and sensitive detection of ochratoxin A in wine 显示文摘 | BARTHELMEBS L JONCA J HAYAT A | 2011 | Food Control2011，22，5： | 1 |
| 4 | Purification of flavonoid from Gingko biloba extract by zinc complexation method and its effect on antioxidant activity 显示文摘 | Zhang J Yue L Hayat K | 2010 | Sep Purif Technol2010，71，3： | 1 |
| 5 | Tool and lubrication for negative incremental forming of a Commercially pure titanium sheet 显示文摘 | Hussain G Gao L Hayat N | 2008 | Journal of Materials Processing Technology2008，203，123： | 1 |
| 6 | The formability of annealed and pre-aged AA-2024 sheets in single-point incremental forming 显示文摘 | HUSSAIN G GAO L HAYAT N DARN | 2010 | The International Journal of Advanced Manufacturing Technology2010，46，5678： | 1 |
| 7 | Aptasensor and genosensor methods for detection of microbes in real world samples 显示文摘 | Paniel N Baudart J Hayat A Barthelmebs L | | Methods0，64，3： | 1 |
| 8 | Evidence for the presence of a reversible Ca2+-dependent pore activated by oxidative stress in heart mitochondria显示文摘 | CROMPTON M COSTI A HAYAT L | 1987 | Biochem J1987，245，3： | 1 |
| 9 | Characteristics and antioxidant activity of uhrafihrated Maillard reaction products from a casein- glucose model system显示文摘 | Gu F L Kim J M Hayat K | 2009 | Food Chemistry2009，117，1： | 1 |
| 10 | Heat - induced alterations in cell membrane permeability and inactivation of transformed morse fibroblasts显示文摘 | Hayat H Friedberg L | 1986 | Int J Hyperthermia1986，2，4： | 1 |
| 11 | Characteristics and antioxidant activity of ultrafiltrated Maillard reaction products from a casein-glucose model system显示文摘 | GU F L KIM J M HAYAT K | 2009 | Food Chemistry2009，117，1： | 1 |
| 12 | Harpin, a hypersensitive response elicitor from Erwinia amylovora regulates ion channel activities in Arabidopsis thallana suspension cells FEBS letters显示文摘 | HAYAT E L MARIE A B JEAN P R | 2001 | The Federation of European Biochemcal Societies2001，497，23： | 1 |
| 13 | Purification of flavonoid from Gingko biloba extract by zinc complexation method and its effect on antioxidant activity 显示文摘 | Zhang J Yue L Hayat K | 2010 | Separation and Purification Technology2010，71，： | 1 |
| 14 | Enzyme - Linked Aptamer Assays (ELAAs), based on a competition format for a rapid and sensitive detection of Ochratoxin A in wine 显示文摘 | Barthelmebs L Jonca J Hayat A | 2011 | Food Control2011，22，5： | 1 |
| 15 | Effect of ultrafiltration and fining adsorbents on the clarification of green tea 显示文摘 | Rao L Hayat K Lv Y | 2011 | J Food Eng2011，102，4： | 1 |
| 16 | Image compression algorithms for fast parallel thinning of binary images显示文摘 | HAYAT L SANDLER M B | 1990 | Electronics Letters1990，26，14： | 1 |
| 17 | Characteristics and antioxidantactivity of ultrafiltrated Maillard products from a casein-glucose modelsystem reaction显示文摘 | GU F L KIM J M HAYAT K | 2009 | Food Chemistry2009，117，1： | 1 |
| 18 | Enzyme-linked aptamer assays ( ELAAs), based on a competition format for a rap- id and sensitive detection of ochratoxin A in wine显示文摘 | BARTHELMEBS L JONCAJ HAYAT A | 2011 | Food Con- trol2011，22，： | 1 |
| 19 | Effect of uhrafiltration and fining adsorbents on the clarification of green tea显示文摘 | Rao L Hayat K Lv Y | 2011 | Journal of Food Engineering2011，102，4： | 1 |
| 20 | Enzyme - Linked Aptamer Assays ( ELAAs), based on a competition format for a rapid and sensitive detection of Ochratoxin A in wine显示文摘 | Barthelmebs L Jonca J Hayat A | 2011 | Food Control2011，22，5： | 1 |
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