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| 1 | High-Resolution Genome-wide Association Study Identifies Genomic Regions and Candidate Genes for Important Agronomic Traits in Wheat显示文摘Wheat(Triticum aestivum)is a major staple food crop worldwide.Genetic dissection of important agronomic traits is essential for continuous improvement of wheat yield to meet the demand of the world's growing population.We conducted a large-scale genome-wide association study(GWAS)using a panel of 768 wheat cultivars that were genotyped with 327609 single-nucleotide polymorphisms generated by genotyping-by-sequencing and detected 395 quantitative trait loci(QTLs)for 12 traits under 7 environments.Among them,273 QTLs were delimited to≤1.0-Mb intervals and 7 of them are either known genes(Rht-D,Vrn-B1,and Vrn-D1)that have been cloned or known QTLs(TaGA2ox8,APO1,TaSus1-7B,and Rht12)that were previously mapped.Eight putative candidate genes were identified for three QTLs that enhance spike seed setting and grain size using gene expression data and were validated in three bi-parental populations.Protein sequence analysis identified 33 putative wheat orthologs that have high identity with rice genes in QTLs affecting similar traits.Large r^2 values for additive effects observed among the QTLs for most traits indicated that the phenotypes of these identified QTLs were highly predictable.Results from this study demonstrated that significantly increasing GWAS population size and marker density greatly improves detection and identification of candidate genes underlying a QTL,solidifying the foundation for large-scale QTL fine mapping,candidate gene validation,and developing functional markers for genomics-based breeding in wheat. | Yunlong Pang Chunxia Liu Danfeng Wang Paul St.Amand Amy Bernardo Wenhui Li Fang He Linzhi Li Liming Wang Xiufang Yuan Lei Dong Yu Su Huirui Zhang Meng Zhao Yunlong Liangi Hongze Jia Xitong Shen Yue Lu Hongming Jiang Yuye Wu Anfei Li Honggang Wang Lingrang Kong Guihua Bai Shubing Liu | 2020 | Molecular Plant2020,13,9: | 8 |
| 2 | Prevalence of Cardiovascular Disease Risk Factor Clustering Among the Adult Population of China: Results From the International Collaborative Study of Cardiovascular Disease in Asia (InterAsia)显示文摘 | Dongfeng Gu Anjali Gupta Paul Muntner Shengshou Hu Xiufang Duan Jichun Chen Robert F. Reynolds Paul K. Whelton Jiang He | 2005 | Circulation2005,,5: | 4 |
| 3 | Prevalence of the metabolic syndrome and overweight among adults in China显示文摘 | Dongfeng Gu Kristi Reynolds Xigui Wu Jing Chen Xiufang Duan Robert F Reynolds Paul K Whelton Jiang He | 2005 | 2005 (9468)2005,,9468: | 3 |
| 4 | Geographic variations in the prevalence, awareness, treatment and control of hypertension in China显示文摘 | Kristi Reynolds Dongfeng Gu Paul Muntner Xigui Wu Jing Chen Guanyong Huang Xiufang Duan Paul K Whelton Jiang He | 2003 | Journal of Hypertension2003,,7: | 2 |
| 5 | Prevalence of the metabolic syndrome and overweight among adults in China显示文摘 | Dongfeng Gu Kristi Reynolds Xigui Wu Jing Chen Xiufang Duan Robert F Reynolds Paul K Whelton Jiang He | 2005 | The Lancet . 2005 (9468)2005,,9468: | 2 |
| 6 | Decreased expression of updated NESG1 in nasopharyngeal carcinoma: its potential role and preliminarily functional mechanism 显示文摘 | LIU Zhen LI Xin HE Xiufang | 2011 | Int J Cancer2011,128,11: | 1 |
| 7 | Characterization of Pectobacterium carotovorum subsp, carotovorurn causing soft-rot disease on Pinellia ternata in China显示文摘 | Hu Xiufang Ying Feixiang He Yubo | 2008 | Eur J Plant Pathol2008,120,3: | 1 |
| 8 | Prevalence, Awareness, Treatment, and Control of Hypertension in China显示文摘 | Dongfeng Gu Kristi Reynolds Xigui Wu Jing Chen Xiufang Duan Paul Muntner Guanyong Huang Robert F. Reynolds Shaoyong Su Paul K. Whelton Jiang He | 2002 | Hypertension: Journal of the American Heart Association2002,,6: | 1 |
| 9 | Decreased expression of updated NESG1 in nasopharyngeal carcinoma: its potential role and preliminarily functional mechanism 显示文摘 | LIU Zhen Li Xin HE Xiufang | 2011 | Int J Cancer2011,128,11: | 1 |
| 10 | Prevalence, Awareness, Treatment, and Control of Hypertension in China显示文摘 | Dongfeng Gu Kristi Reynolds Xigui Wu Jing Chen Xiufang Duan Paul Muntner Guanyong Huang Robert F. Reynolds Shaoyong Su Paul K. Whelton Jiang He | 2002 | Hypertension: Journal of the American Heart Association2002,,6: | 1 |
| 11 | Effect of potassium supplementation on blood pressure in Chinese: a randomized, placebo-controlled trial显示文摘 | Dongfeng Gu Jiang He Xigui Wu Xiufang Duan Paul K. Whelton | 2001 | Journal of Hypertension2001,,7: | 1 |
| 12 | Specific antibody immobilization with biotin-poly(1-1ysine)-g-poly(ethylene glycol)and protein A on microfluidic chips显示文摘 | Wen Xiufang He Hongyan Lee L J | | 0,,1: | 1 |
| 13 | Variation in plant diversity and dominance across dune fixation stages in the Chinese steppe zone显示文摘Aims Our aim was to study how diversity and dominance of plant species and plant functional types(PFTs)change and covary across three dune fixation stages in the Chinese steppe zone.Methods In the Chinese steppe zone,we measured coverage,mean height and density of each plant species in three types of dunes(mobile,semi-fixed and fixed dunes)in four sites(Mu Us,Otindag,Hulunbeir and Horqin).Plant species were grouped into 24 PFTs according to their lifespan,photosynthetic pathway,reproductive mode and life form.Dominance of each plant species and PFT were determined,and species diversity and PFT diversity were quantified using Shannon–Wiener index.Important Findings PFT diversity was positively related to plant species diversity in each dune stage,but PFT diversity increased more with increasing plant species diversity in the mobile and semi-fixed dunes than in the fixed dunes.Dune fixation stage explained 87.2%of the variation in plant species diversity and 84.8%of the variation in PFT diversity.Dominant species and PFTs differed among the three dune fixation stages;the more fixed the dunes were,the more perennial,shrubby,clonal and C3 species co-dominated.Specifically,in mobile dunes annual C4 non-clonal herbs were the most dominant,and in semi-fixed and fixed dunes perennial C3 clonal shrubs were most dominant. | Jianjiang Qiao Weiwei Zhao Xiufang Xie Guofang Liu Xuehua Ye Yu Chu Hui He Ming Dong | 2012 | Journal of Plant Ecology2012,5,3: | 1 |