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| 1 | High-resolution microendoscopy for esophageal cancer screening in China: A cost-effectiveness analysis显示文摘AIM:To study the cost-effectiveness of high-resolution microendoscopy(HRME)in an esophageal squamous cell carcinoma(ESCC)screening program in China.METHODS:A decision analytic Markov model of ESCC was developed.Separate model analyses were conducted for cohorts consisting of an averagerisk population or a high-risk population in China.Hypothetical 50-year-old individuals were followed until age 80 or death.We compared three different strategies for both cohorts:(1)no screening;(2)standard endoscopic screening with Lugol’s iodine staining;and(3)endoscopic screening with Lugol’s iodine staining and an HRME.Model parameters were estimated from the literature as well as from GLOBOCAN,the Cancer Incidence and Mortality Worldwide cancer database.Health states in the model included non-neoplasia,mild dysplasia,moderate dysplasia,high-grade dysplasia,intramucosal carcinoma,operable cancer,inoperable cancer,and death.Separate ESCC incidence transition rates were generated for the average-risk and high-risk populations.Costs in Chinese currency were converted to international dollars(I$)and were adjusted to 2012dollars using the Consumer Price Index.RESULTS:The main outcome measurements for this study were quality-adjusted life years(QALYs)and incremental cost-effectiveness ratio(ICER).For the average-risk population,the HRME screening strategy produced 0.043 more QALYs than the no screening strategy at an additional cost of I$646,resulting in an ICER of I$11808 per QALY gained.Standard endoscopic screening was weakly dominated.Among the high-risk population,when the HRME screening strategy was compared with the standard screening strategy,the ICER was I$8173 per QALY.For both the high-risk and average-risk screening populations,the HRME screening strategy appeared to be the most cost-effective strategy,producing ICERs below the willingness-topay threshold,I$23500 per QALY.One-way sensitivity analysis showed that,for the average-risk population,higher specificity of Lugol’s iodine(>40%)and lower specificity of HRME(<70%)could make Lugol’s iodine screening cost-effective.For the high-risk population,the results of the model were not substantially affected by varying the follow-up rate after Lugol’s iodine screening,Lugol’s iodine test characteristics(sensitivity and specificity),or HRME specificity.CONCLUSION:The incorporation of HRME into an ESCC screening program could be cost-effective in China.Larger studies of HRME performance are needed to confirm these findings. | Chin Hur Sung Eun Choi Chung Yin Kong Gui-Qi Wang Hong Xu Alexandros D Polydorides Li-Yan Xue Katherine E Perzan Angela C Tramontano Rebecca R Richards-Kortum Sharmila Anandasabapathy | 2015 | World Journal of Gastroenterology2015，21，18： | 8 |
| 2 | Outcomes after arthroscopic repair of rotator cuff tears in the setting of mild to moderate glenohumeral osteoarthritis显示文摘BACKGROUND Rotator cuff pathology is a very common source of shoulder pain.Similarly,osteoarthritis of the glenohumeral joint can cause shoulder pain and produce similar symptoms.Surgical management can be indicated for both pathologies,however,outcomes data is limited when examining rotator cuff repair(RCR) in the setting of glenohumeral arthritis(GHOA).Thus,this study sought to determine outcomes for patients who undergo RCR in the setting of GHOA.AIM To evaluate if a relationship exists between outcomes of RCR in the setting of GHOA.METHODS This was a retrospective analysis of patients who underwent arthroscopic rotator cuff repair with concurrent glenohumeral osteoarthritis between 2010-2017.Patients were stratified based on rotator cuff tear size and glenohumeral osteoarthritis severity.Cohorts were paired 1:1 with patients without glenohumeral osteoarthritis.Patients included had a minimum two year follow-up.Rate of conversion to total shoulder arthroplasty,complication rates following initial surgery,and patient-reported outcome measures were collected.RESULTS A total of 142 patients were included.The number of patients that required total shoulder arthroplasty within two years after index surgery was low.2/71(2.8%) patients with GHOA,and 1/71(1.4%) without GHOA.Following rotator cuff repair,both groups showed favorable patientreported outcomes.CONCLUSION Patients with glenohumeral osteoarthritis who underwent arthroscopic rotator cuff repair showed comparable outcomes to patients without glenohumeral osteoarthritis. | Ian S Hong Allison J Rao Tyler L CarlLee Joshua D Meade Daniel J Hurwit Gregory Scarola David P Trofa Shadley C Schiffern Nady Hamid Patrick M Connor James E Fleischli Bryan Michael Saltzman | 2022 | World Journal of Orthopedics2022，13，7： | 2 |
| 3 | Immunomodulating effects of synchronised plasmapheresis and intravenous bolus cyclophosphamide in systemic lupus erythematosus显示文摘 | Hong C Zayed E | 1995 | Lupus1995，4，6： | 1 |
| 4 | Clinical value of ezrin expres- sion in primary osteosareoma显示文摘 | Kim C Shin E Hong S | 2009 | Cancer Res Treat2009，41，3： | 1 |
| 5 | Acute respiratory symp- toms in adults in general practice显示文摘 | Hong C Y Lin R T 'Fan E S | 2004 | Faro Pract2004，21，3： | 1 |
| 6 | Over-expression of tobacco NtHSP70 1 contributes to drought-stress tolerance in plants 显示文摘 | CHO E HONG C | 2006 | Plant Cell Reports2006，25，4： | 1 |
| 7 | A novel mechanism to ensure terminal initiation by hepatitis C virus NS5B polymerase显示文摘 | Hong Z Cameron C E Walker M P | 2001 | Virology2001，285，： | 1 |
| 8 | Synthesis of polystyrene microspheres by dispersion polymerization using poly (vinyl alcohol) as a steric stabilizer in aqueous alcohol media显示文摘 | Hong J Hong C K Shim S E | | 0，，01： | 1 |
| 9 | Tunable refractive index of magnetic fluids and its applications 显示文摘 | C Y Hong H E Horng S Y Yang | 2004 | Physica Status Solidi C2004，1，7： | 1 |
| 10 | Modeling of Globular and Dendritic Structure Evolution in Solidification of an Al-7mass%Si Alloy 显示文摘 | M E Zhu C P Hong | 2001 | ISIJ2001，41，： | 1 |
| 11 | Indirect pathogenicity ofHaemophilus influenzae and Moraxella catarrhalis in polymicrobialotitis media occurs via interspecies quorum signaling显示文摘 | Armbruster C E Hong W Pang B | 2010 | MBio2010，1，3： | 1 |
| 12 | Basolateral ammonium transport by the mouse inner medullary collecting duct cell (mlMCD-3)显示文摘 | Handlogten M E Hong S P Westhof C M | 2004 | Am J Physiol Renal Physiol2004，287，4： | 1 |
| 13 | Perineural dexmedetomidine added to ropivacaine for sciatic nerve block in rats prolongs the duration of analgesia by blocking the hyperpolarization-activated cation current显示文摘 | BRUMMETT C M HONG E K JANDA A M | 2011 | Anesthesiology2011，115，4： | 1 |
| 14 | Electroencephalographic study of drowsiness insimulated driving with sleep deprivation显示文摘 | HONG J E MIN K C KIM S H | 2005 | International Journal of Industrial Ergonomics2005，35，4： | 1 |
| 15 | Translation elongation factor 1-α gene from Pichia pastoris:molecular cloning,sequence,and use of its promoter显示文摘 | Ahn J Hong J Lee H Park M Lee E Kim C Choi E Jung J Lee H | 2007 | Applied Microbiology and Biotechnology2007，74，： | 1 |
| 16 | Nitric oxide function and signaling in plant disease resistance 显示文摘 | Hong J K Yun B W Kang J G Raja M U Kwon E Sorhagen K Chu C C Wang Y Q Loake G J | 2008 | Journal of Experimental Botany2008，59，2： | 1 |
| 17 | Clinical value of ezrin expression inprimary osteosarcoma显示文摘 | Kim C Shin E Hong Sf | 2009 | Cancer Res Treat2009，41，3： | 1 |
| 18 | Utilization of housefly - maggots, a feed supplement in the production of broiler chickens 显示文摘 | HWANGBO J HONG E C JANG A | 2009 | Journal of Environmental Biology2009，30，4： | 1 |
| 19 | 查看详情显示文摘 | Chen Y F Yang S Y Tse W S Horng H E Hong C Y Yang H C | | 0，，： | 1 |
| 20 | Ordered Structures in Fe3O4 Kerosene-Based Ferrofluids 显示文摘 | HONG C Y JANG I J HORNG H E | 1997 | Journal of Applied Physics1997，81，8： | 1 |
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