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| 1 | Monte Carlo simulation of GEM-based for 14 MeV neutron detector显示文摘A new concept of neutron detector based on Gas Electron Multiplier(GEM) technology is presented in this paper,in which a novel multi-layer high density polyethylene(HDPE) as neutron-to-proton converter is proposed and studied with Geant4 toolkit for fast 14 MeV neutron.Our preliminary results show that the detection efficiency of the detector with 400 converter units is higher than 2.3% and reconstruction accuracy of the incident neutron position is higher than 2.6%. | WANG XiaoDong ZHANG YuLian ZHANG ChunHui HU BiTao | 2013 | Science China(Physics,Mechanics & Astronomy)2013，56，9： | 3 |
| 2 | Broadband isolated attosecond pulse generation in a two-color laser field combined with an orthogonally polarized laser pulse显示文摘We present a method to generate broadband isolated attosecond pulses. Using a two-color laser field, which is synthesized by a mid-infrared (12.5 fs, 2000 nm) and a weaker (12 fs, 800 nm) pulse in the x direction, a modulated supercontinuum from 290 to 430 eV is obtainable. By properly adding a second-harmonic control field of the driving pulse in the y direction, the short quantum path is well selected and a smooth supercontinuum from 290 to 440 eV is generated. The bandwidth of the supercontinuum can be controlled by adjusting the electric field of the control pulse in the x direction. When the electric field increases to 0.051 a.u., a smooth supercontinuum from 295 to 520 eV is obtained. Using this method we expect that isolated 63-as attosecond pulses with tunable central wavelengths are straightforwardly obtained. | DU HongChuan WANG XiaoShan HU BiTao | 2012 | Science China(Physics,Mechanics & Astronomy)2012，55，1： | 2 |
| 3 | Study on the Clinical Effectiveness of Thymectomy for Myasthenia Gravis显示文摘Objectiv:To investigate the theoretical basis and clinical significance of thymectomy in the treatment of myasthenia gravis (MG). Methods:Analyze the changes in the contents of serum AchRab and sIL-2R, lymphocyte subtypes in Peripheral blood lymphocytes before and after thymectomy in 69 patients. Results:In the study group significant changes were found in serum contents of AchRab and sIL-2R before and after operation and there was also remarkable change in the number and constitution of peripheral blood lymphocyte subtypes. Conclusion:Thymectomy is an effective therapy for MG. | PAN Tiecheng, YAN Hua, ZHANG Ni, PAN Youming, TANG Yingxiong, WEN Xiang, SONG Dingwei, HU Ming, LIU Ligang, LIU Zixiong, YANG Mingshan, XU Jinzhi, PU Bitao, GAO Boting Department of Thoracis Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China | 2002 | The Chinese-German Journal of Clinical Oncology2002，1，1： | 1 |
| 4 | Isolated attosecond pulse generation combining propagation effects and a modulated chirped polarization gating technique显示文摘We propose a theoretical scheme to generate a broadband supercontinuum using a modulated chirped polarization gating technique. By this technique, a broadband continuum of 155 eV can be obtained at microscopic level. The modulations on the supercontinuum can be eliminated after propagation. Then a smooth broadband supercontinuum with the bandwidth of 155 eV can be generated. As a result, isolated sub-100-attosecond pulses with tunable central wavelengths could be obtained straightforwardly. Our simulations also reveal that an isolated attosecond pulse can still be generated by using multicycle driving laser pulses, and the central wavelength of isolated attosecond pulse can be controlled by adjusting the delay τd (τd is the delay of the two counter-rotating circularly polarized pulses.). | DU HongChuan LUO LaoYong WANG XiaoShan HU BiTao | 2013 | Science China(Physics,Mechanics & Astronomy)2013，56，5： | 1 |
| 5 | Erythrocyte membrane-camouflaged nanoworms with on-demand antibiotic release for eradicating biofilms using near-infrared irradiation显示文摘The increase in the number of resistant bacteria caused by the abuse of antibiotics and the emergence of biofilms significantly reduce the effectiveness of antibiotics.Bacterial infections are detrimental to our life and health.To reduce the abuse of antibiotics and treat biofilm-related bacterial infections,a biomimetic nano-antibacterial system,RBCM-NW-G namely,that controls the release of antibiotics through near infrared was prepared.The hollow porous structure and the high surface activity of nanoworms are used to realize antibiotic loading,and then,biomimetics are applied with red blood cell membranes(RBCM).RBCM-NW-G,which retains the performance of RBCM,shows enhanced permeability and retention effects.Fluorescence imaging in mice showed the effective accumulation of RBCM-NW-G at the site of infection.In addition,the biomimetic nanoparticles showed a longer blood circulation time and good biocompatibility.Anti-biofilm test results showed damage to biofilms due to a photothermal effect and a highly efficient antibacterial performance under the synergy of the photothermal effect,silver iron,and antibiotics.Finally,by constructing a mouse infection model,the great potential of RBCM-NW-G in the treatment of in vivo infections was confirmed. | Luoxiao Ran Bitao Lu Haoyu Qiu Guofang Zhou Jing Jiang Enling Hu Fangyin Dai Guangqian Lan | 2021 | Bioactive Materials2021，6，9： | 1 |
| 6 | Digital coincidence acquisition applied to portable β liquid scintillation counting device显示文摘A digital coincidence acquisition system applied to a portable liquid scintillation counting device is developed. The system which simplifies the device design consists of a digitizer card of Agilent U1066A DC438, a discriminator and a host computer. The anode analog pulses from two photomultiplier tubes are captured by the system, which adopts the sequence acquisition storage mode. By choosing proper threshold for each channel, coincidence time window of ±30 ns, and comparing the pulse amplitudes from two channels, the portable scintillation counting device can be used to detect β particles. For the unquenched standard 3 H sample, the results show that the detection efficiency is (58.5±0.1)% and the background is (86.7±0.7) cpm. Meanwhile, 3 H β spectrum is obtained. | REN Zhongguo HU Bitao ZHAO Zhiping LI Dongcang | 2013 | Nuclear Science and Techniques2013，24，3： | 0 |
| 7 | Microcluster colloidosomes for hemostat delivery into complex wounds:A platform inspired by the attack action of torpedoes显示文摘Complex yet lethal wounds with uncontrollable bleeding hinder conventional hemostats from clotting blood at the source or deep sites of injury vasculature,thereby causing massive blood loss and significantly increased mortality.Inspired by the attack action of torpedoes,we synthesized microcluster(MC)colloidosomes equipped with magnetic-mediated navigation and“blast”systems to deliver hemostats into the cavity of vase-type wounds.CaCO_(3)/Fe_(2)O_(3)(CF)microparticles functionalized with Arg-Gly-Asp(RGD)modified polyelectrolyte multilayers were co-assembled with oppositely charged zwitterionic carbon dots(CDs)to form MC colloidosomes,which were loaded with thrombin and protonated tranexamic acid(TXA-NH_(3)^(+)).The composite microparticles moved against blood flow under magnetic mediation and simultaneously disassembled for the burst release of thrombin stimulated by TXA-NH_(3)^(+).The CO_(2) bubbles generated during disassembly produced a“blast”that propelled thrombin into the wound cavity.Severe bleeding in a vase-type hemorrhage model in the rabbit liver was rapidly controlled within~60 s.Furthermore,in vivo subcutaneous muscle and liver implantation models demonstrated excellent biodegradability of MC colloidosomes.This study is the first to propose a novel strategy based on the principle of torpedoes for transporting hemostats into vase-type wounds to achieve rapid hemostasis,creating a new paradigm for combating trauma treatment. | Bitao Lu Enling Hu Ruiqi Xie Kun Yu Fei Lu Rong Bao Chenhui Wang Guangqian Lan Fangyin Dai | 2022 | Bioactive Materials2022，7，10： | 0 |
| 8 | Experimental Study of the Elastic Scattering of^(10)Be on^(208)Pb at the Energy around Three Times of the Coulomb Barrier显示文摘Elastic scattering is the simplest nuclear process and has been widely used to investigate the structure of the interacting nuclei[1,2]. | Duan Fangfang Yang Yanyun Pang Danyang Hu Bitao Wang Jiansong Wang Kang Yang Guo Valdir Guimaraes Ma Peng Xu Shiwei Liu Xingquan Ma Junbing Bai Zhen Hu Qiang Shu Jinya Sun Xinxin Yao Jiasheng Qi Hangkai Sun Zhiyu | 2019 | IMP & HIRFL Annual Report2019，，1： | 0 |
| 9 | Band Structure in Doubly Odd ~17Ta Nucleus显示文摘BandStructureinDoublyOdd~170TaNucleus￥ZhangYuhu;ZhaoQingzhong;ZhouXiaohong;XuHushan;GuoYinxiang;LeiXiangguo;LuJun;ZhuShaofei;?.. | Zhang Yuhu Zhao Qingzhong Zhou Xiaohong Xu Hushan Guo Yinxiang Lei Xiangguo Lu Jun Zhu Shaofei Huang Wenxue Liu Zhong Gou Quanbu Jin Hanjuan Hu Bitao Luo Yixiao Sun Xiangfu Zhu Yongtai Wen Shukian and Wu Shaoguang (The China Institute of Ato | 1996 | IMP & HIRFL Annual Report1996，，1： | 0 |
| 10 | Magnetic field-mediated Janus particles with sustained driving capability for severe bleeding control in perforating and inflected wounds显示文摘Severe bleeding in perforating and inflected wounds with forky cavities or fine voids encountered during prehospital treatments and surgical procedures is a complex challenge.Therefore,we present a novel hemostatic strategy based on magnetic field-mediated guidance.The biphasic Janus magnetic particle(MSS@Fe2O3-T)comprised aggregates ofα-Fe2O3 nanoparticles(Fe_(2)O_(3) NPs)as the motion actuator,negatively modified microporous starch(MSS)as the base hemostatic substrate,and thrombin as the loaded hemostatic drug.Before application,the particles were first wrapped using NaHCO_(3) and then doped with protonated tranexamic acid(TXA-NH_(3)^(+)),which ensured their high self-dispersibility in liquids.During application,the particles promptly self-diffused in blood by bubble propulsion and travelled to deep bleeding sites against reverse rushing blood flow under magnetic guidance.In vivo tests confirmed the superior hemostatic performance of the particles in perforating and inflected wounds(“V”-shaped femoral artery and“J”-shaped liver bleeding models).The present strategy,for the first time,extends the range of magnetically guided drug carriers to address the challenges in the hemorrhage control of perforating and inflected wounds. | Qing Li Enling Hu Kun Yu Mengxing Lu Ruiqi Xie Fei Lu Bitao Lu Rong Bao Guangqian Lan | 2021 | Bioactive Materials2021，6，12： | 0 |
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