|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Association between tea consumption and cognitive function in cognitively healthy older adults and older adults with mild cognitive impairment显示文摘Background Prospective studies suggest that tea consumption may decrease the risk for cognitive impairment in late life.However,little research has examined the association between tea consumption and cognitive performance across multiple domains.In addition,no research has examined the benefit of tea consumption on cognitive performance among older adults with existing impairment.Aims The current study examined the association between tea consumption and performance on tasks of global cognitive function,episodic memory and executive function in cognitively healthy(CH)older adults and older adults with mild cognitive impairment(MCI).Methods The analytical sample included 1849 community-dwelling older adults from the Shanghai Brain Aging Study(65.6%female,mean age of 69.50(8.02)years).Following ascertainment of cognitive function,816 were categorised as MCI.In addition to completion of a demographics questionnaire,participants reported their tea consumption and completed a battery of tests to measure global cognitive function,episodic memory and working memory.Results Independent analyses of covariance revealed a significant association between tea consumption and measures of episodic memory;however,these associations were restricted to CH older adults but not older adults with MCI.Tea consumption was not associated with working memory performance.Conclusions The current study suggests that the benefit of tea consumption is restricted to cognitively healthy older adults and does not extend to older adults with MCI. | Hua Xu Alexandra J Fiocco Xiaohua Liu Tao Wang Guanjun Li Shifu Xiao the research group of Shanghai Brain Aging Study | 2021 | General Psychiatry2021，34，4： | 2 |
| 2 | Lipoprotein lipase and phospholipid transfer protein overexpression in human glioma cells and their effect on cell growth, apoptosis, and migration显示文摘Glioma 是在大脑的普通肿瘤之一。脂蛋白脂肪分解酵素(LPL ) 或 phospholipid 转移蛋白质(PLTP ) 的表示水平可以影响有临床、病理学的参数的 glioma 前进和它的关系。在 glioma 的 LPL 或 PLTP 表示的临床的意义没被建立。在现在的学习,在 glioma 肿瘤的 LPL 和 PLTP 层次被调查,在 LPL 和 PLTP 水平和恶意的 glioma 的等级之间的关系被分析,与提供为在临床、基本的研究背景的 gliomas 的诊断和治疗的新想法的目的。LPL 和 PLTP mRNA 和蛋白质层次比在更低的等级肿瘤的那些在等级 IV glioma 是显著地更高的(P P = 0.005 ) 。LPL 和 PLTP 的层次与 glioma 病人的弄短的幸存被增加(P LPL 和 PLTP 导致了减少的房间生长和移植,但是在 vitro 增加了 apoptosis。另外,当 cyclin 依赖的 kinase 禁止者 p16, p21,和 Rb 是起来调整的时,周期相关的 cyclins 和他们的搭挡被发现下面调整的房间。而且, LPL 或 PLTP 击倒导致了 pro-apoptotic 分子的起来规定和 anti-apoptotic 分子的下面规定。在 U251 房间的 LPL 或 PLTP 的脱离导致了上皮的间充质的转变标记和侵略分子矩阵 metalloproteinases 的下面规定。LPL 和 PLTP 看起来是新奇联系 glioma 的蛋白质并且在人的 glioma 的前进起一个作用。 | Weijiang Dong Huilin Gong Guanjun Zhang Simona Vuletic John Albers Jiaojiao Zhang Hua Liang Yanxia Sui Jin Zheng | 2017 | Acta Biochimica et Biophysica Sinica2017，49，1： | 2 |
| 3 | Engineering Deinococcus radiodurans into biosensor to monitor radioactivity and genotoxicity in environment显示文摘Based on a genetically modified radioresistant bacteria Deinococcus radiodurans, we constructed a real time whole cell biosensor to monitor radioactivity and genotoxicity in highly radioactive environ-ment. The enhanced green fluorescence protein (eGFP) was fused to the promoter of the crucial DNA damage-inducible recA gene from D. radiodurans, and the consequent DNA fragment (PrecA-egfp) car-ried by plasmid was introduced into D. radiodurans R1 strain to obtain the biosensor strain DRG300. This engineered strain can express eGFP protein and generate fluorescence in induction of the recA gene promoter. Based on the correlation between fluorescence intensity and protein expression level in live D. radiodurans cells, we discovered that the fluorescence induction of strain DRG300 responds in a remarkable dose-dependent manner when treated with DNA damage sources such as gamma radiation and mitomycin C. It is encouraging to find the widely detective range and high sensitivity of this re-constructed strain comparing with other whole cell biosensors in former reports. These results suggest that the strain DRG300 is a potential whole cell biosensor to construct a detective system to monitor the biological hazards of radioactive and toxic pollutants in environment in real time. | GAO GuanJun FAN Lu LU HuiMing HUA YueJin | 2008 | Chinese Science Bulletin2008，53，11： | 2 |
| 4 | Ppd: a general switch responsible for extreme radioresistanee of Deinococcus radiodurans 显示文摘 | Hua Yuejin Narumi Issay Gao Guanjun | 2003 | Biochemical and Biophysical Research Communications2003，306，： | 1 |
| 5 | Expression of Deinococcus radiodurans PprI enhances the radioresistance of Escherichia coli显示文摘 | Guanjun Gao Bing Tian Lili Liu Duohong Sheng Binghui Shen Yuejin Hua | 2003 | DNA Repair2003，，12： | 1 |
| 6 | Combination of radiofrequency ablation and sequential cellular immunotherapy improves progression‐free survival for patients with hepatocellular carcinoma显示文摘 | Jiuwei Cui Nanya Wang Hengjun Zhao Haofan Jin Guanjun Wang Chao Niu Hiroshi Terunuma Hua He Wei Li | 2014 | Int. J. Cancer2014，，： | 1 |
| 7 | Efficient photocatalytic hydrogen evolution coupled with benzaldehyde production over 0D Cd_(0.5)Zn_(0.5)S/2D Ti_(3)C2 Schottky heterojunction显示文摘Converting water into hydrogen fuel and oxidizing benzyl alcohol to benzaldehyde simultaneously under visible light illumination is of great significance,but the fast recombination of photogenerated carriers in photocatalysts seriously decreases the conversion efficiency.Herein,a novel dual-functional 0D Cd_(0.5)Zn_(0.5)S/2D Ti_(3)C2 hybrid was fabricated by a solvothermally in-situ generated assembling method.The Cd_(0.5)Zn_(0.5)S nano-spheres with a fluffy surface completely and uniformly covered the ultrathin Ti_(3)C2 nanosheets,leading to the increased Schottky barrier(SB)sites due to a large contact area,which could accelerate the electron–hole separation and improve the light utilization.The optimized Cd_(0.5)Zn_(0.5)S/Ti_(3)C2 hybrid simultaneously presents a hydrogen evolution rate of 5.3 mmol/(g·h)and a benzaldehyde production rate of 29.3 mmol/(g·h),which are~3.2 and 2 times higher than those of pristine Cd_(0.5)Zn_(0.5)S,respectively.Both the multiple experimental measurements and the density functional theory(DFT)calculations further demonstrate the tight connection between Cd_(0.5)Zn_(0.5)S and Ti_(3)C2,formation of Schottky junction,and efficient photogenerated electron–hole separation.This paper suggests a dual-functional composite catalyst for photocatalytic hydrogen evolution and benzaldehyde production,and provides a new strategy for preventing the photogenerated electrons and holes from recombining by constructing a 0D/2D heterojunction with increased SB sites. | Junnan TAO Mingyuan WANG Guiwu LIU Qinqin LIU Lei LU Neng WAN Hua TANG Guanjun QIAO | 2022 | Journal of Advanced Ceramics2022，11，7： | 1 |
| 8 | Expression of Deinococcus radiodurans PprI enhances the radioresistance of Escherichia coli显示文摘 | Guanjun Gao Bing Tian Lili Liu Duohong Sheng Binghui Shen Yuejin Hua | 2003 | DNA Repair2003，，12： | 1 |
| 9 | PprI: a general switch responsible for extreme radioresistance of Deinococcus radiodurans显示文摘 | Yuejin Hua Issay Narumi Guanjun Gao Bing Tian Katsuya Satoh Shigeru Kitayama Binghui Shen | 2003 | Biochemical and Biophysical Research Communications2003，，2： | 1 |
| 10 | Constitutive equation and dynamic recrystallization behavior of as-cast 254SMO super-austenitic stainless steel显示文摘 | Ying Han Hua Wu Wei Zhang Dening Zou Guiwu Liu Guanjun Qiao | 2015 | Materials and Design2015，，： | 1 |
| 11 | Synthesis and characterization of multi-walled carbon nanotubes rein- forced polyamide 6 via in situ polymerization 显示文摘 | ZHAO Chungui HUA Guanjun YAN J | 2005 | Polymer2005，46，： | 1 |
| 12 | Study and performance test of 10 kW molten carbonate fuel cell power generation system显示文摘The use of high-temperature fuel cells as a power technology can improve the efficiency of electricity generation and achieve near-zero emissions of carbon dioxide.This work explores the performance of a 10 kW high-temperature molten carbonate fuel cell.The key materials of a single cell were characterized and analyzed using X-ray diffraction and scanning electron microscopy.The results show that the pore size of the key electrode material is 6.5 lm and the matrix material is a-LiAlO_(2).Experimentally,the open circuit voltage of the single cell was found to be 1.23 V.The current density was greater than 100 mA/cm^(2)at an operating voltage of 0.7 V.The 10 kW fuel cell stack comprised 80 single fuel cells with a total area of 2000 cm^(2)and achieved an open circuit voltage of greater than 85 V.The fuel cell stack power and current density could reach 11.7 kW and 104.5 mA/cm2 at an operating voltage of 56 V.The influence and long-term stable operation of the stack were also analyzed and discussed.The successful operation of a 10 kW high-temperature fuel cell promotes the large-scale use of fuel cells and provides a research basis for future investigations of fuel cell capacity enhancement and distributed generation in China. | Chengzhuang Lu Ruiyun Zhang Guanjun Yang Hua Huang Jian Cheng Shisen Xu | 2021 | International Journal of Coal Science & Technology2021，8，3： | 0 |
| 13 | Advances in the Application of Perovskite Materials显示文摘Nowadays, the soar of photovoltaic performance of perovskite solar cells has set off a fever in the study of metal halide perovskite materials. The excellent optoelectronic properties and defect tolerance feature allow metal halide perovskite to be employed in a wide variety of applications. This article provides a holistic review over the current progress and future prospects of metal halide perovskite materials in representative promising applications, including traditional optoelectronic devices(solar cells, light-emitting diodes, photodetectors, lasers), and cutting-edge technologies in terms of neuromorphic devices(artificial synapses and memristors) and pressure-induced emission. This review highlights the fundamentals, the current progress and the remaining challenges for each application, aiming to provide a comprehensive overview of the development status and a navigation of future research for metal halide perovskite materials and devices. | Lixiu Zhang Luyao Mei Kaiyang Wang Yinhua Lv Shuai Zhang Yaxiao Lian Xiaoke Liu Zhiwei Ma Guanjun Xiao Qiang Liu Shuaibo Zhai Shengli Zhang Gengling Liu Ligang Yuan Bingbing Guo Ziming Chen Keyu Wei Aqiang Liu Shizhong Yue Guangda Niu Xiyan Pan Jie Sun Yong Hua Wu‑Qiang Wu Dawei Di Baodan Zhao Jianjun Tian Zhijie Wang Yang Yang Liang Chu Mingjian Yuan Haibo Zeng Hin‑Lap Yip Keyou Yan Wentao Xu Lu Zhu Wenhua Zhang Guichuan Xing Feng Gao Liming Ding | 2023 | Nano-Micro Letters2023，15，10： | 0 |
| 14 | Diagnostic accuracy of cystoscopic biopsy for tumour grade in outpatients with urothelial carcinoma of the bladder and the risk factors of upgrading显示文摘Objective:To assess the concordance of tumour grade in specimens obtained from diagnostic cystoscopic biopsy and transurethral resection of bladder tumour(TURBT)and explore the risk factors of upgrading.Methods:The medical records of 205 outpatients who underwent diagnostic cystoscopic biopsy before initial TURBT were retrospectively reviewed.Comparative analysis of the tumour grade of biopsy and operation specimens was performed.Tumour grade changing from low-grade to high-grade with or without variant histology was defined as upgrading.Logistic regression an-alyses were performed to identify the risk factors of upgrading.Results:For the 205 patients,the concordance of tumour grade between specimens obtained from biopsy and operation was 0.639.The concordance for patients who were preoperatively diagnosed with low-grade and high-grade was 0.504 and 0.912,respectively.Univariate and multivariate logistic regression analyses showed that older age,tumour multifocality,high neutrophil-to-lymphocyte ratio(NLR),platelet-to-lymphocyte ratio(PLR),and low lymphocyte-to-monocyte ratio(LMR)were significantly associated with upgrading(odds ratio ranging from 0.412 to 4.364).The area under the curve of the different multivariate models was improved from 0.752 to 0.821,and decision curve analysis demonstrated a high net benefit when NLR,LMR,and PLR were added.Conclusion:Diagnostic cystoscopic biopsy may not accurately represent the true grade of primary bladder cancer,especially for outpatients with low-grade bladder cancer.Moreover,older age,tumour multifocality,high NLR,PLR,and low LMR are risk factors of upgrading,and systemic inflammatory markers improve the predictive ability. | Junjie Fan Hua Liang Jinhai Fan Lei Li Guanjun Zhang Xinqi Pei Tao Yang Dalin He Kaijie Wu | 2023 | Asian Journal of Urology2023，10，1： | 0 |
| 15 | Superdeformed Bands in ~(167)Lu显示文摘SuperdeformedBandsin^(167)LuWuXiaoguang;YangChunxiang;chengHua;LiuXiangan;ShenCaiwan;ChenYongshou;MaYingjun;LuJingbin;WenShux... | Wu Xiaoguang Yang Chunxiang cheng Hua Liu Xiangan Shen Caiwan Chen Yongshou Ma Yingjun Lu Jingbin Wen Shuxian Li Guangsheng Li Shenggang Yuan Guanjun Weng Peikun Liu Yunzuo( Department of Physics, Jinn University, Changchun, 130023) | 1996 | 中国原子能科学研究院年报1996，，1： | 0 |
| 16 | Ring-like nucleoid does not play a key role in radioresistance of Deinococcus radiodurans显示文摘The conclusion based on transmission electron microscopy, 'the tightly packed ring-like nucleoid of the Deinococcus radiodurans R1 is a key to radioresistance', has instigated lots of debates. In this study, according to the previous research of PprI’s crucial role in radioresistance of D. radiodurans, we have attempted to examine and compare the nucleoid morphology differences among wild-type D. ra-diodurans R1 strain, pprI function-deficient mutant (YR1), and pprI function-complementary strains (YR1001, YR1002, and YR1004) before and after exposure to ionizing irradiation. Fluorescence mi-croscopy images indicate: (1) the majority of nucleoid structures in radioresistant strain R1 cells ex-hibit the tightly packed ring-like morphology, while the pprI function-deficient mutant YR1 cells carrying predominate ring-like structure represent high sensitivity to irradiation; (2) as an extreme radioresistant strain similar to wild-type R1, pprI completely function-complementary strain YR1001 almost displays the loose and irregular nucleoid morphologies. On the other hand, another radioresistant pprI partly function-complementary strain YR1002’s nucleiods exhibit about 60% ring-like structure; (3) a PprI C-terminal deletion strain YR1004 consisting of approximately 60% of ring-like nucleoid is very sensi-tive to radiation. Therefore, our present experiments do not support the conclusion that the ring-like nucleoid of D. radiodurans does play a key role in radioresistance. | GAO GuanJun, LU HuiMing, YIN LongFei & HUA YueJin Institute of Nuclear-Agricultural Sciences, Zhejiang University, Hangzhou 310029, China | 2007 | Science China(Life Sciences)2007，50，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员