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1266篇 您的检索式:作者名="Haga"
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1Radiation pneumonitis after stereotactic radiation therapy for lung cancer显示文摘Stereotactic body radiation therapy(SBRT)has a locacontrol rate of 95%at 2 years for non-small cell lungcancer(NSCLC)and should improve the prognosis oinoperable patients,elderly patients,and patients withsignificant comorbidities who have early-stage NSCLCThe safety of SBRT is being confirmed in internationalmulti-institutional PhaseⅡtrials for peripheral lungcancer in both inoperable and operable patients,bureports so far have found that SBRT is a safe and effective treatment for early-stage NSCLC and early metastatic lung cancer.Radiation pneumonitis(RP)is oneof the most common toxicities of SBRT.Although mospost-treatment RP is Grade 1 or 2 and either asymptomatic or manageable,a few cases are severe,symptomatic,and there is a risk for mortality.The reportedrates of symptomatic RP after SBRT range from 9%to28%.Being able to predict the risk of RP after SBRT isextremely useful in treatment planning.A dose-effecrelationship has been demonstrated,but suggesteddose-volume factors like mean lung dose,lung V20and/or lung V2.5 differed among the reports.We foundthat patients who present with an interstitial pneumo-nitis shadow on computed tomography scan and high levels of serum Krebs von den Lungen-6 and surfactant protein D have a high rate of severe radiation pneumo-nitis after SBRT.At our institution,lung cancer patients with these risk factors have not received SBRT since 2006,and our rate of severe RP after SBRT has de-creased significantly since then.Hideomi Yamashita Wataru Takahashi Akihiro Haga Keiichi Nakagawa 2014World Journal of Radiology2014,6,9:22
2Nonalcoholic fatty liver disease and hepatic cirrhosis: comparison with viral hepatitis-associated steatosis显示文摘Nonalcoholic fatty liver disease(NAFLD) including nonalcoholic steatohepatitis(NASH) is globally increasing and has become a world-wide health problem. Chronic infection with hepatitis B virus or hepatitis C virus(HCV) is associated with hepatic steatosis. Viral hepatitis-associated hepatic steatosis is often caused by metabolic syndrome including obesity,type 2 diabetes mellitus and/or dyslipidemia. It has been reported that HCV genotype 3 exerts direct metabolic effects that lead to hepatic steatosis. In this review,the differences between NAFLD/NASH and viral hepatitis-associated steatosis are discussed.Yuki Haga Tatsuo Kanda Reina Sasaki Masato Nakamura Shingo Nakamoto Osamu Yokosuka 2015World Journal of Gastroenterology2015,21,46:20
3Current management of patients with hepatocellular carcinoma显示文摘The current management therapies for hepatocellular carcinoma(HCC) patients are discussed in this review. Despite the development of new therapies, HCC remains a 'difficult to treat' cancer because HCC typically occurs in advanced liver disease or hepatic cirrhosis. The progression of multistep and multicentric HCC hampers the prevention of the recurrence of HCC. Many HCC patients are treated with surgical resection and radiofrequency ablation(RFA), although these modalities should be considered in only selected cases with a certain HCC number and size. Although there is a shortage of grafts, liver transplantation has the highest survival rates for HCC. Several modalities are salvage treatments; however, intensive care in combination with other modalities or in combination with surgical resection or RFA might offer a better prognosis. Sorafenib is useful for patients with advanced HCC. In the near future, HCC treatment will include stronger molecular targeted drugs, which will have greater potency and fewer adverse events. Further studies will be ongoing.Tatsuo Kanda Sadahisa Ogasawara Tetsuhiro Chiba Yuki Haga Masao Omata Osamu Yokosuka 2015World Journal of Hepatology2015,7,15:15
4Bone status assessment in Japanese subjects using speed of sound along the tibiaNobuyuki Miyatake Hiroko Muta Chigusa Murota Mari Haga Masafumi Fujii 2002Chinese Medical Journal2002,,2:9
5Bone marrow cell-based regenerative therapy for liver cirrhosis显示文摘Bone marrow cells are capable of differentiation into liver cells.Therefore,transplantation of bone marrow cells has considerable potential as a future therapy for regeneration of damaged liver tissue.Autologous bone marrow infusion therapy has been applied to patients with liver cirrhosis,and improvement of liver function parameters has been demonstrated.In this review,we summarize clinical trials of regenerative therapy using bone marrow cells for advanced liver diseases including cirrhosis,as well as topics pertaining to basic in vitro or in vivo approaches in order to outline the essentials of this novel treatment modality.Takafumi Saito Kyoko Tomita Hiroaki Haga Kazuo Okumoto Yoshiyuki Ueno 2013World Journal of Methodology2013,3,4:6
6Sofosbuvir treatment and hepatitis C virus infection显示文摘Hepatitis C virus(HCV) infection is a serious problem worldwide.The use of interferon-based therapy has made HCV eradication challenging.The recent appearance of direct-acting antiviral agents(DAAs) has changed HCV therapy.Combining the use of DAAs with peginterferon and ribavirin has improved treatment efficacy.Furthermore,the combination of different orally administered DAAs has enabled interferon-free therapy with much higher efficacy and safety.In particular,sofosbuvir,a nucleotide-based NS5 B inhibitor,prevents HCV RNA synthesis by acting as a 'chain terminator'.Treatment with sofosbuvir has attained an extremely high rate of sustained virologic response.The current review summarizes the efficacy and safety of sofosbuvir therapy.Masato Nakamura Tatsuo Kanda Yuki Haga Reina Sasaki Shuang Wu Shingo Nakamoto Shin Yasui Makoto Arai Fumio Imazeki Osamu Yokosuka 2016World Journal of Hepatology2016,8,3:4
7Impact of Rituximab Desensitization on Blood‐Type‐Incompatible Adult Living Donor Liver Transplantation: A Japanese Multicenter Study显示文摘H. Egawa S. Teramukai H. Haga M. Tanabe A. Mori T. Ikegami N. Kawagishi H. Ohdan M. Kasahara K. Umeshita 2014American Journal of Transplantation2014,,1:3
8Patterns and quantities of NH 3 , N 2 O and CH 4 emissions during swine manure composting without forced aeration––effect of compost pile scale显示文摘Yasuyuki Fukumoto Takashi Osada Dai Hanajima Kiyonori Haga 2003Bioresource Technology2003,,2:2
9The role of Toll-like receptors in the host response to viruses显示文摘Andrew G. Bowie Ismar R. Haga 2004Molecular Immunology2004,,8:2
10Current status of liver transplantation across ABO blood-type barrier显示文摘Egawa H Ohdan H Haga H 2008Journal of Hepato-Biliary-Pancreatic Surgery2008,,02:2
11The Presence of Foxp3 Expressing T Cells Within Grafts of Tolerant Human Liver Transplant Recipients显示文摘Ying Li Xiangdong Zhao Donghua Cheng Hironori Haga Tatsuaki Tsuruyama Kathryn Wood Shimon Sakaguchi Koichi Tanaka Shinji Uemoto Takaaki Koshiba 2008Transplantation2008,,12:2
12Patterns and quantities of NH 3 , N 2 O and CH 4 emissions during swine manure composting without forced aeration––effect of compost pile scale显示文摘Yasuyuki Fukumoto Takashi Osada Dai Hanajima Kiyonori Haga 2003Bioresource Technology2003,,2:2
13Outcomes of Adult-to-Adult Living Donor Liver Transplantation: A Single Institution?s Experience With 335 Consecutive Cases显示文摘Daisuke Morioka Hiroto Egawa Mureo Kasahara Takashi Ito Hironori Haga Yasutsugu Takada Hiroshi Shimada Koichi Tanaka 2007Annals of Surgery2007,,2:2
14Molecular basis of the effects of shear stress on vascular endothelial cells显示文摘Yi-Shuan J. Li Jason H. Haga Shu Chien 2004Journal of Biomechanics2004,,10:2
15Requirement of Protocol Biopsy Before and After Complete Cessation of Immunosuppression After Liver Transplantation显示文摘Mami Yoshitomi Takaaki Koshiba Hironori Haga Ying Li Xiangdong Zhao Donghua Cheng Aya Miyagawa Hiromi Sakashita Tatsuaki Tsuruyama Hidenori Ohe Mikiko Ueda Shinya Okamoto Hiroto Egawa Kathryn Wood Shimon Sakaguchi Toshiaki Manabe Koichi Tanaka Shinji Uemo 2009Transplantation2009,,4:2
16Intracellular accumulation of unconjugated bilirubin inhibits phytohemagglutin -induced proliferation and interleukin - 2 production of human lymphocytes显示文摘Haga Y Tempero MA Kay D 1996Dig Dis Sci1996,41,7:1
17Detection of glomerular and nonglomerular red blood cells by antomatet urinary sediment analyzer显示文摘Hyodo T Kumanok Haga M 1998Clin Lab Sci1998,11,1:1
18Catalytic properties of supported cobalt catalysts for steam reforming of ethanol显示文摘Haga F Nakajima T Yamashita K 1997Catal Lett1997,48,:1
19High-quality ZnO films prepared on Si wafers by low-pressure MOCVD 显示文摘HAGA K SUZUKI T KASHIWABA Y 2003Thin Solid Films2003,433,:1
20Preparation of ZnO films by atmospheric pressure chemical-vapor deposition using zinc aceylacetonate and ozone显示文摘Haga K Katahira K 1999Thin Solid Films1999,,:1
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