|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Proso Millet Protein Elevates Plasma Level of High-Density Lipoprotein:A New Food Function of Proso Millet显示文摘We examined the effects of dietary proso-millet protein on plasma levels of high-density lipoprotein (HDL) cholesterol in different rats from animals reported in our previous studies. The results showed also, in this animal, that the ingestion of the millet protein elevates plasma levels of HDL-cholesterol like our earlier works. Taking into account the anti-atherogenic function of HDL, therefore, the millet protein would be useful as a new food ingredient which has the function that regulates cholesterol | N. NISHIZAWA S. SHIMANUKI H. FUJIHASHI H. WATANABE Y. FUDAMOTO AND T. NAGASAWA (Department of Bioscience and Technology, Faculty of Agriculture, Iwate University Morioka, Iwate 020, Japan Research Laboratory,Nitto Best Co., Ltd, Sagae, Yamagata 991 Ka | 1996 | Biomedical and Environmental Sciences1996，9，2： | 24 |
| 2 | Generalized crack initiation and crack damage stress thresholds of brittle rock masses near underground excavations显示文摘 | M Cai P.K Kaiser Y Tasaka T Maejima H Morioka M Minami | 2004 | International Journal of Rock Mechanics and Mining Sciences2004，，5： | 9 |
| 3 | Crosstalk between angiogenesis, cytokeratin-18, and insulin resistance in the progression of non-alcoholic steatohepatitis显示文摘AIM: To elucidate the possible crosstalk between angiogenesis, cytokeratin-18 (CK-18), and insulin resistance (IR) especially in patients with non-alcoholic steatohepatitis (NASH).METHODS: Twenty-eight patients with NASH and 11 with simple fatty liver disease (FL) were enrolled in this study and underwent clinicopathological examination. The measures of angiogenesis, CK-18, and IR employed were CD34-immunopositive vessels, CK-18immunopositive cells, and homeostasis model assessment of IR (HOMA-IR), respectively. The correlations of these factors with NASH were elucidated.RESULTS: Significant development of hepatic neovascularization was observed only in NASH, whereas almost no neovascularization could be observed in FL and healthy liver. The degree of angiogenesis was almost parallel to liver fibrosis development, and both parameters were positively correlated. Similarly, CK-18expression and HOMA-R were signifi cantly increased in NASH as compared with FL and healthy liver. Furthermore, CK-18 and HOMA-IR were also positively correlated with the degree of neovascularization. CONCLUSION: These results indicate that the crosstalk between angiogenesis, CK-18, and IR may play an important role in the onset and progression of NASH. | Mitsuteru Kitade Hitoshi Yoshiji Ryuichi Noguchi Yasuhide Ikenaka Kosuke Kaji Yusaku Shirai Masaharu Yamazaki Masahito Uemura Junichi Yamao Masao Fujimoto Akira Mitoro Masahisa Toyohara Masayoshi Sawai Motoyuki Yoshida Chie Morioka Tatsuhiro Tsujimoto Hideto Kawaratani Hiroshi Fukui | 2009 | World Journal of Gastroenterology2009，15，41： | 9 |
| 4 | Usefulness of urinary trypsinogen-2 and trypsinogen activation peptide in acute pancreatitis:A multicenter study in Japan显示文摘BACKGROUND Rapid urinary trypsinogen-2 dipstick test and levels of urinary trypsinogen-2 and trypsinogen activation peptide(TAP) concentration have been reported as prognostic markers for the diagnosis of acute pancreatitis.AIM To reconfirm the validity of all these markers in the diagnosis of acute pancreatitis by undertaking a multi-center study in Japan.METHODS Patients with acute abdominal pain were recruited from 17 medical institutions in Japan from April 2009 to December 2012. Urinary and serum samples were collected twice, at enrollment and on the following day for measuring target markers. The diagnosis and severity assessment of acute pancreatitis were assessed based on prognostic factors and computed tomography(CT) Grade of the Japanese Ministry of Health, Labour, and Welfare criteria.RESULTS A total of 94 patients were enrolled during the study period. The trypsinogen-2 dipstick test was positive in 57 of 78 patients with acute pancreatitis(sensitivity,73.1%) and in 6 of 16 patients with abdominal pain but without any evidence of acute pancreatitis(specificity, 62.5%). The area under the curve(AUC) score of urinary trypsinogen-2 according to prognostic factors was 0.704, which was highest in all parameter. The AUC scores of urinary trypsinogen-2 and TAP according to CT Grade were 0.701 and 0.692, respectively, which shows higher than other pancreatic enzymes. The levels of urinary trypsinogen-2 and TAP were significantly higher in patients with extended extra-pancreatic inflammation as evaluated by CT Grade.CONCLUSION We reconfirmed urinary trypsinogen-2 dipstick test is useful as a marker for the diagnosis of acute pancreatitis. Urinary trypsinogen-2 and TAP may be considered as useful markers to determine extra-pancreatic inflammation in acute pancreatitis. | Hiroaki Yasuda Keisho Kataoka Yoshifumi Takeyama Kazunori Takeda Tetsuhide Ito Toshihiko Mayumi Shuji Isaji Tetsuya Mine Motoji Kitagawa Seiki Kiriyama Junichi Sakagami Atsushi Masamune Kazuo Inui Kenji Hirano Ryukichi Akashi Masamichi Yokoe Yoshio Sogame Kazuichi Okazaki Chie Morioka Yasuyuki Kihara Shigeyuki Kawa Masao Tanaka Akira Andoh Wataru Kimura Isao Nishimori Junji Furuse Isao Yokota Tooru Shimosegawa | 2019 | World Journal of Gastroenterology2019，25，1： | 7 |
| 5 | FLAC/PFC coupled numerical simulation of AE in large-scale underground excavations显示文摘 | M. Cai P.K. Kaiser H. Morioka M. Minami T. Maejima Y. Tasaka H. Kurose | 2006 | International Journal of Rock Mechanics and Mining Sciences2006，，4： | 4 |
| 6 | Generalized crack initiation and crack damage stress thresholds of brittle rock masses near underground excavations显示文摘 | M Cai P.K Kaiser Y Tasaka T Maejima H Morioka M Minami | 2004 | International Journal of Rock Mechanics and Mining Sciences2004，，5： | 3 |
| 7 | Duodenal-type follicular lymphoma more than 10 years after treatment intervention:A retrospective single-center analysis显示文摘BACKGROUND Duodenal-type follicular lymphoma(D-FL)has been recognized as a rare entity that accounts for approximately 4%of primary gastrointestinal lymphomas.D-FL follows an indolent clinical course compared with common nodal FL and is generally considered to have a better prognosis.Therefore,the“watch and wait”approach is frequently adopted as the treatment method.Alternatively,there is an option to actively intervene in D-FL.However,the long-term outcomes of such cases are poorly understood.AIM To clarify the clinical outcomes after long-term follow-up in cases of D-FL with treatment intervention.METHODS We retrospectively analyzed patients who met the following criteria:the lesion was confirmed by endoscopy,the diagnosis of D-FL was confirmed histopathologically,and the patient was followed-up for more than 10 years after the intervention at our center.RESULTS We identified 5 cases of D-FL.Two patients showed a small amount of bone marrow involvement(Stage IV).Rituximab was used as a treatment for remission in all 5 patients.It was also used in combination with chemotherapy in 2 Stage IV patients as well as for maintenance treatment.Radiation therapy was performed in 2 cases,which was followed by complete remission(CR).Eventually,all 5 patients achieved CR and survived for more than 10 years.However,3 patients experienced recurrence.One patient achieved a second CR by retreatment,and in another case,the lesion showed spontaneous disappearance.The remaining patient had systemic widespread recurrence 13 years after the first CR.Biopsy results suggested that the FL lesions were transformed into diffuse large B-cell lymphoma.The patient died 4 years later despite receiving various chemotherapies.CONCLUSION In this study,the treatment for patients of D-FL in Stage IV was successful.In the future,criteria for how to treat“advanced”D-FL should be established based on additional cases.This study of patients with D-FL indicates that whole-body follow-up examinations should continue for a long time due to a fatal recurrence 13 years after reaching CR. | Makoto Saito Akio Mori Shihori Tsukamoto Takashi Ishio Emi Yokoyama Koh Izumiyama Masanobu Morioka Takeshi Kondo Hirokazu Sugino | 2022 | World Journal of Gastrointestinal Oncology2022，14，8： | 3 |
| 8 | Genetic Parameters for Milk,Fat Yield and Age at First Calving of Chinese Holsteins in Heilongjiang显示文摘Genetic parameters for milk,fat yield and age at first calving of Chinese Holsteins in Heilongjiang were evaluated using multiple trait restricted maximum likelihood procedures with an animal model.Data consisted of records of 2496 Chinese Holsteins first lactation cows collected from 1989 to 2000.The model included 21 herd effects,four calving season effects,nine age at first calving effects,6697 animal effects.(Co)variance components of milk yield,fat yield and age at first calving were estimated with the software package for variance component estimation(VCE) by an animal model. The heritabilities were 0.14,0.21,0.38 for milk yield,fat yield and age at first calving,respectively.The estimates of genetic correlation between milk yield and fat yield,age at first calving were 0.96,-0.29,respectively.The estimate of genetic correlation between fat yield and age at first calving was -0.28. | Ding Ke wei,Takeo Kayaba (The United Graduate School of Agricultural Science,Iwate Uniersity,Morioka Shi,020-8550,Japan) | 2001 | Journal of Northeast Agricultural University(English Edition)2001，8，2： | 2 |
| 9 | FLAC/PFC coupled numerical simulation of AE in large-scale underground excavations显示文摘 | M. Cai P.K. Kaiser H. Morioka M. Minami T. Maejima Y. Tasaka H. Kurose | 2006 | International Journal of Rock Mechanics and Mining Sciences2006，，4： | 2 |
| 10 | Small hepatocellular carcinoma with ring calcification:A case report and literature review显示文摘Ring calcification in untreated hepatocellular carcinoma(HCC) is extremely rare,with only 3 previously reported cases in the English-language literature.A case of HCC with ring calcification was reported in this paper.Additionally,3 previously reported cases of HCC with ring calcification were reviewed.In 3 of these 4 cases(including our case),surgery was performed.Although the size of the ring-calcified lesion ranged from 3.0-3.7 cm in previously reported cases,the size was only 1 cm in ours.The differentiation of the tumor was moderate in the 2 previously reported cases in the histological findings and poor in ours.In spite of their poor differentiation for their sizes,these tumors showed no early enhancement in dynamic computed tomography.All calcified tumors showed a thick fibrous capsule and extensive necrosis histologically.Ring calcification was considered to result from a circulatory disturbance caused by the imbalance between the less abundant arterial blood flow and high inner pressure induced by either the thick fibrous capsule or vigorous proliferation due to the poor differentiation.Ring calcification in untreated HCC may suggest a lower differentiation of the tumor.Even if its size is small,hepatic resection should be performed for any tumor with ring calcification because poor differentiation is considered to be one of the risk factors for recurrence after local ablation therapy,including radio frequency ablation. | Takashi Murakami Daisuke Morioka Hideki Takakura Yasuhiko Miura Shinji Togo | 2013 | World Journal of Gastroenterology2013，19，1： | 2 |
| 11 | Back-analysis of rock mass strength parameters using AE monitoring data显示文摘 | M. Cai H. Morioka P.K. Kaiser Y. Tasaka H. Kurose M. Minami T. Maejima | 2006 | International Journal of Rock Mechanics and Mining Sciences2006，，4： | 2 |
| 12 | Outcomes of Adult-to-Adult Living Donor Liver Transplantation: A Single Institution?s Experience With 335 Consecutive Cases显示文摘 | Daisuke Morioka Hiroto Egawa Mureo Kasahara Takashi Ito Hironori Haga Yasutsugu Takada Hiroshi Shimada Koichi Tanaka | 2007 | Annals of Surgery2007，，2： | 2 |
| 13 | Frontal skull base surgery combined with endonasal endoscopic sinus surgery显示文摘 | Morioka M Hamada J Yano S | 2005 | Surg Neurol2005，64，1： | 1 |
| 14 | Arteriovenous fistulas at the cervicomedullary junction presenting with subarachnoid hemorrhage: six cases reports with special reference to the angiographic pattern of venous drainage 显示文摘 | KAI Y HAMADA J MORIOKA M | 2005 | Am J Neuroradiol2005，26，8： | 1 |
| 15 | Double microcatheter technique for endovascular coiling of wide-neck aneurysms using a new guiding device for the transcarotid approach:technical note显示文摘 | Kai Y Hamada J Morioka M | 2005 | Neuroradiology2005，47，1： | 1 |
| 16 | Receptor for advanced glycation end products is involved in impaired angiogenic response in diabetes显示文摘 | SHOJI T KOYAMA H MORIOKA T | 2006 | Diabetes2006，55，8： | 1 |
| 17 | Various irrigation fluids affect postoperative brain edema and cellular damage during experimental neurosurgery in rats显示文摘 | Doi K Kawano T Morioka Y | 2006 | Surg Neurol2006，66，6： | 1 |
| 18 | Penile reconstruction: combined use of an innervated forearm osteoeutancous flap and big toe pulp 显示文摘 | Sasaki K Nozaki M Morioka K | 1999 | Plast Reconstr Surg1999，104，4： | 1 |
| 19 | DDB accumulates at DNA damage sites immediately after UV irradiation and directly stimulates nucleotide excision repair显示文摘 | WAKASUGI M KAWASHIMA A MORIOKA H | | 0，，277： | 1 |
| 20 | Coronary vasospasm at the site of myocardial bridge - report of two cases 显示文摘 | Kodama K Morioka N Hara Y | 1998 | Angiology1998，49，8： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员