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| 1 | Study on characteristics of internal solitary waves in the Malacca Strait based on Sentinel-1 and GF-3 satellite SAR data显示文摘The study of the characteristics of internal solitary waves happened in the Malacca Strait is an urgent problem for submarine, ship navigation and marine engineering. Based on SAR remote sensing data obtained from the high spatial resolution Sentinel-1 and GF-3, the internal solitary wave characteristics of the Malacca Strait are investigated. By use of 20 Sentinel-1 SAR images from June 2015 to December 2016 and 24 GF-3 images from April2018 to March 2019, the spatial distribution characteristics of internal solitary wave s are statistically analyzed. It is found that the internal solitary waves are usually in the form of wave packets and single solitary waves, and the maximum crest length of the leading wave can reach 39 km. The amplitude and group velocity of internal solitary wave s can be calculated by the inversion model of high-order nonlinear Schrodinger(NLS) equation, and the calculated amplitude of the internal solitary wave s and the propagation group velocity of the wave packets range from 4.7 m to 23.9 m and 0.12 m/s to 0.40 m/s, respectively. The range of phase velocity of single internal solitary waves obtained by Kd V equation is 0.26 m/s to 0.60 m/s. In general, the amplitude and the velocity of internal solitary wave s in Malacca strait are related to the topography. | Jing Ning Lina Sun Haiji Cui Kexiao Lu Jing Wang | 2020 | Acta Oceanologica Sinica2020，39，5： | 4 |
| 2 | Sulforaphane attenuates dextran sodium sulphate induced intestinal inflammation via IL-10/STAT3 signaling mediated macrophage phenotype switching显示文摘Innate immunity,particularly macrophages,is critical for intestinal homeostasis.Sulforaphane,a dietary isothiocyanate from cruciferous vegetables,has been reported to protect against intestinal inflammation.However,the role of macrophages in sulforaphane mediated intestinal inflammation and the underlying molecular mechanisms have not been studied yet.In this study,sulforaphane effectively attenuated dextran sodium sulphate(DSS)induced intestinal inflammation in murine model.Of note,sulforaphane skewed the switching from classically(M1)to alternatively(M2)activated phenotype both in intestinal and bone marrow-derived macrophages(BMDMs).The expression levels of M1 associated maker genes induced by DSS or lipopolysaccharide(LPS)plus interferon gamma-γ(IFN-γ)were suppressed by sulforaphane while M2 marker gene expression levels were improved.This resulted in alteration of inflammatory mediators,particularly interleukin-10(IL-10),both in colon tissues and culture medium of BMDMs.Subsequently,IL-10 was found to mediate the sulforaphane induced M2 phenotype switching of BMDMs through the activation of STAT3 signaling.This was confirmed by immunofluorescence analysis with increased number of p-STAT3-positive cells in the colon sections.Moreover,anti-IL-10 neutralizing antibody significantly interfered M2 phenotyping of BMDMs induced by sulforaphane with reduced STAT3 phosphorylation.Findings here introduced a potential utilization of sulforaphane for intestinal inflammation treatment with macrophages as the therapeutic targets. | Yuyang Sun Jiqing Tang Cui Li Jun Liu Haijie Liu | 2022 | Food Science and Human Wellness2022，11，1： | 2 |
| 3 | Transplantation of mesenchymal stem cells preconditioned with diazoxide, a mitochon- drial ATP- sensitive potassium channel opener,promotes repair of myocardial infarction in rats显示文摘 | Xiaojun Cui Haijie Wang Haidong Guo | 2010 | Tohoku J Exp Med2010，，220： | 1 |
| 4 | Transcriptomics integrated with metabolomics reveals the mechanism of CaCl_(2)-HCl electrolyzed water-induced glucosinolate biosynthesis in broccoli sprouts显示文摘Glucosinolates are important phytochemicals in Brassicaceae.We investigated the effect of CaCl_(2)-HCl electrolyzed water(CHEW)on glucosinolates biosynthesis in broccoli sprouts.The results showed that CHEW treatment significantly decreased reactive oxygen species(ROS)and malondialdeh yde(MDA)contents in broccoli sprouts.On the the 8^(th)day,compared to tap water treatment,the the total glucosinolate content of broccoli sprouts with CHEW treatment increased by 10.6%and calcium content was dramatically enhanced from 14.4 mg/g DW to 22.7 mg/g DW.Comparative transcriptome and metabolome analyses revealed that CHEW treatment activated ROS and calcium signaling transduction pathways in broccoli sprouts and they interacted through MAPK cascades.Besides,CHEW treatment not only promoted the biosynthesis of amino acids,but also enhanced the expression of structural genes in glucosinolate synthesis through transcription factors(MYBs,bHLHs,WRKYs,etc.).The results of this study provided new insights into the regulatory network of glucosinolates biosynthesis in broccoli sprouts under CHEW treatment. | Cui Li Shuhui Song Yanan He Haijie Liu | 2024 | Food Science and Human Wellness2024，13，2： | 0 |
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