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| 1 | Fine-Tuning of MiR528 Accumulation Modulates Flowering Time in Rice显示文摘In plants,microRNA (miRNA) functions in the post-transcriptional repression of target mRNAs have been well explored.However,the mechanisms regulating the accumulation of miRNAs remain poorly under.stood.Here,we report that distinct mechanisms regulate accumulation of a monocot-specific miRNA,rice (Oryza sativa) miR528.At the transcriptional level,miR528 accumulated to higher levels in older plants than in young seedlings and exhibited aging-modulated gradual accumulation and diurnal rhythms in leaves;at the post-transcriptional level,aging also modulated miR528 levels by enhancing pri-miR528 alter.native splicing.We found that miR528 promotes rice flowering under long-day conditions by targeting RED AND FAR-RED INSENSITIVE2 (OsRFI2).Moreover,natural variations in the MIR528 promoter region caused differences in miR528 expression among rice varieties,which are correlated with their different binding affinities with the transcription factor OsSPL9 that activates the expression of miR528.Taken together,our findings reveal rice plants have evolved sophisticated modes fine-tuning miR528 levels and provide insight into the mechanisms that regulate MIRNA expression in plants. | Rongxin Yang Pingchuan Li Hailiang Mei Dong Wang Jing Sun Chao Yang Lili Hao Shouyun Cao Chengcai Chu Songnian Hu Xianwei Song Xiaofeng Cao | 2019 | Molecular Plant2019，12，8： | 12 |
| 2 | Genome-Wide Analysis of the Sus Gene Family in Cotton显示文摘蔗糖 synthase (怀疑) 是在植物蔗糖新陈代谢的关键酶。在棉花,怀疑(EC 2.4.1.13 ) 是降级的主要的酶从种子上衣的韧皮部进口进棉花纤维的蔗糖。这研究示威了 Gossypium arboreum L. 的染色体, G。raimondii Ulbr,和 G。hirsutum L. ,包含了 8, 8,和 15 分别地怀疑基因。他们的结构的组织,种系发生的关系,和表示侧面被描绘。genomic 和编码序列的比较识别了哪个高度被保存在之间的多重 introns,数字和位置双并且 allotetraploid 棉花种类。大多数种系发生的 clades 从所有三种包含了序列,建议 tetraploid G 的 Sus 基因。hirsutum 它的双祖先源于那些。一个人怀疑组(怀疑我) 在棉花期间经历了扩大进化。表示分析显示大多数怀疑基因差别在各种各样的纸巾被表示并且在棉花纤维房间有发展依赖者表示侧面。一样的 orthologous 组的成员在所有三种有很类似的表示模式。这些结果提供新卓见进棉花的进化在纤维生长和开发期间怀疑基因家庭,和卓见进它的成员的生理的功能。 | Changsong Zou Cairui Lu Haihong Shang Xinrui Jing Hailiang Cheng Youping Zhang Guoli Song | 2013 | Journal of Integrative Plant Biology2013，55，7： | 10 |
| 3 | Transcriptome analysis reveals long noncoding RNAs involved in fiber development in cotton (Gossypium arboreum)显示文摘Long noncoding RNAs(lnc RNAs)play important roles in various biological regulatory processes in yeast,mammals,and plants.However,no systematic identification of lnc RNAs has been reported in Gossypium arboreum.In this study,the strand-specific RNA sequencing(ss RNA-seq)of samples from cotton fibers and leaves was performed,and lnc RNAs involved in fiber initiation and elongation processes were systematically identified and analyzed.We identified 5,996 lnc RNAs,of which 3,510 and 2,486 can be classified as long intergenic noncoding RNAs(linc RNAs)and natural antisense transcripts(lnc NAT),respectively.Linc RNAs and lnc NATs are similar in many aspects,but have some differences in exon number,exon length,and transcript length.Expression analysis revealed that 51.9%of linc RNAs and 54.5%of lnc NATs transcripts were preferentially expressed at one stage of fiber development,and were significantly highly expressed than protein-coding transcripts(21.7%).During the fiber and rapid elongation stages,rapid and dynamic changes in lnc RNAs may contribute to fiber development in cotton.This work describes a set of lnc RNAs that are involved in fiber development.The characterization and expression analysis of lnc RNAs will facilitate future studies on their roles in fiber development in cotton. | Changsong Zou Qiaolian Wang Cairui Lu Wencui Yang Youping Zhang Hailiang Cheng Xiaoxu Feng Mtawa Andrew Prosper Guoli Song | 2016 | Science China(Life Sciences)2016，59，2： | 9 |
| 4 | The utilization of water resources and its variation tendency in Tarim River Basin显示文摘水资源有效利用在 Tarim 是生态的改进和经济开发的关键河盆。在整个河盆分析水资源利用和它的变化趋势是必要的。在八个气象学的车站和十五个水文学车站基于监视数据和形成,时间系列的方法,回归分析被用于在特别在源流和主流的区域分析水资源利用和变化趋势最近 10 年。量的结果显示源流区域的流入在过去的 40 年里有一个增加的趋势到不同程度。增加趋势的流量从 1994 ~ 2002 是更重要的,它证明在源流的水资源条件在一个优点。然而,与 25 的体积在水的条件下面增加# | YE Mao XU Hailiang SONG Yudong | 2006 | Chinese Science Bulletin2006，51，A01： | 6 |
| 5 | The superiority of multi-trait models with genotype-by-environment interactions in a limited number of environments for genomic prediction in pigs显示文摘Background: Different production systems and climates could lead to genotype-by-environment(G × E) interactions between populations, and the inclusion of G × E interactions is becoming essential in breeding decisions. The objective of this study was to investigate the performance of multi-trait models in genomic prediction in a limited number of environments with G × E interactions.Results: In total, 2,688 and 1,384 individuals with growth and reproduction phenotypes, respectively, from two Yorkshire pig populations with similar genetic backgrounds were genotyped with the PorcineSNP80 panel.Single-and multi-trait models with genomic best linear unbiased prediction(GBLUP) and BayesC π were implemented to investigate their genomic prediction abilities with 20 replicates of five-fold cross-validation.Our results regarding between-environment genetic correlations of growth and reproductive traits(ranging from 0.618 to 0.723) indicated the existence of G × E interactions between these two Yorkshire pig populations. For single-trait models, genomic prediction with GBLUP was only 1.1% more accurate on average in the combined population than in single populations, and no significant improvements were obtained by BayesC π for most traits. In addition, single-trait models with either GBLUP or BayesC π produced greater bias for the combined population than for single populations. However, multi-trait models with GBLUP and BayesC π better accommodated G × E interactions,yielding 2.2% – 3.8% and 1.0% – 2.5% higher prediction accuracies for growth and reproductive traits, respectively,compared to those for single-trait models of single populations and the combined population. The multi-trait models also yielded lower bias and larger gains in the case of a small reference population. The smaller improvement in prediction accuracy and larger bias obtained by the single-trait models in the combined population was mainly due to the low consistency of linkage disequilibrium between the two populations, which also caused the BayesC π method to always produce the largest standard error in marker effect estimation for the combined population.Conclusions: In conclusion, our findings confirmed that directly combining populations to enlarge the reference population is not efficient in improving the accuracy of genomic prediction in the presence of G × E interactions, while multi-trait models perform better in a limited number of environments with G × E interactions. | Hailiang Song Qin Zhang Xiangdong Ding | 2021 | Journal of Animal Science and Biotechnology2021，12，1： | 6 |
| 6 | The dynamic variation of water resources and its tendency in theTarim River Basin显示文摘The method of time series is applied to analyze the variation of precipitation and temperature from 1961 to 2002 in the mountainous areas ofthe Tarim RiverBasin,as wellas water consumption in the headstream and mainstream areas. Those hydrologic parameters are verified. Quantitative results indicate thatthe precipitation and temperature in the headstream areas have an increasing trend to differentextent.The increasing trend ofprecipitation islesssignificantthan thatof the temperature (!= 0.05).Runoffofthree headstreams also increases especially from 1994 to 2002. Compared with the perennialrunoff,the annualrunoffhas increased by 25.163×108 m3/a.However, inflowsofthe mainstream areashasonly increased by 0.9985×108 m3/a.So the runoffatthe different hydrologic stationsin the headstream areashasa lineardecreasing trend.Itisshown thatthe degraded trend ofeco-environmentofthe Tarim RiverBasin hardly changesin the specialwaterperiod forten consecutiveyears.Given runoffofthreeheadstreamsisaccounted in normalperiod from 1957 to 2003, the annualrunoffofthe headstream areas would be only 22.57×108 m3.Therefore,more attention should begiven to ecologicalsafety oftheTarim RiverBasin. | XU Hailiang YE Mao SONG Yudong | 2005 | Journal of Geographical Sciences2005，15，4： | 5 |
| 7 | Precise editing of methylated cytosine in Arabidopsis thaliana using a human APOBEC3Bctd-Cas9 fusion显示文摘Dear Editor,Precise editing of specific genomic sites holds great promise in basic research and modern crop breeding,and some cytosine base editors(CBEs)have been developed for this purpose(Komor et al.,2016;Zong et al.,2018). | Zhi-Hong Liu Shanjie Tang Wentao Hu Ruo Lv Hailiang Mei Rongxin Yang Xianwei Song Xiaofeng Cao Dong Wang | 2022 | Science China(Life Sciences)2022，65，1： | 3 |
| 8 | Reliability evaluation on sense-switch p-channel flash显示文摘In this paper,the reliability of sense-switch p-channel flash is evaluated extensively.The endurance result indicates that the p-channel flash could be programmed and erased for more than 10000 cycles;the room temperature read stress shows negligible influence on the p-channel flash cell;high temperature data retention at 150℃ is extrapolated to be about 5 years and 53 years corresponding to 30% and 40% degradation in the drive current,respectively.Moreover,the electrical parameters of the p-channel flash at different operation temperature are found to be less affected.All the results above indicate that the sense-switch p-channel flash is suitable to be used as the configuration cell in flash-based FPGA. | Side Song Guozhu Liu Hailiang Zhang Lichao Chao Jinghe Wei Wei Zhao Genshen Hong Qi He | 2021 | Journal of Semiconductors2021，42，8： | 2 |
| 9 | The effect of continuous Ni(Ⅱ) exposure on the organic degradation and soluble microbial product(SMP) formation in two-phase anaerobic reactor显示文摘A two-phase anaerobic reactor fed with glucose substrate(3 g chemical oxygen demand(COD)/L) was used to investigate the effects of toxic metals on the degradation of organics and the soluble microbial product(SMP) formation. Low concentrations of Ni(II)(5 and10 mg/L) promoted the acid phase, whereas high concentrations(15, 20, and 25 mg/L)exhibited an inhibitory effect on, but did not alter the fermentative method, which mainly involved the fermentation of propionic acid. The methanogenic microorganism exhibited a strong capability adapting constantly increased Ni(II) levels. The acid phase was an accumulation stage of SMP. In the absence of Ni(II), the high-molecular-weight material in the effluent SMP mainly contained polysaccharide, tryptophan, and casein. Methanogens metabolized most of the polysaccharide, the whole tryptophan content, and part of the casein, leading to the presence of humic acid and protein in effluent. After Ni(II) dosage, the protein and polysaccharide of the acid phase increased, and tryptophan changed, while casein remained stable. More protein than polysaccharide was produced, suggesting the prominent function of protein when addressing the negative effect of toxic metals. The analysis of DNA confirmed the change of bacterial activity. | Wei Wu Tengteng Duan Hailiang Song Yan Li Ang Yu Long Zhang Aimin Li | 2015 | Journal of Environmental Sciences2015，27，7： | 2 |
| 10 | Quasi-neutral limit of the full bipolar Euler-Poisson system显示文摘The quasi-neutral limit of the multi-dimensional non-isentropic bipolar Euler-Poisson system is considered in the present paper. It is shown that for well-prepared initial data the smooth solution of the non-isentropic bipolar Euler-Poisson system converges strongly to the compressible non-isentropic Euler equations as the Debye length goes to zero. | JIANG Song JU QiangChang LI HaiLiang LI Yong | 2010 | Science China Mathematics2010，53，12： | 2 |
| 11 | Role of biologic components in a novel floating-bed combining Ipomoea aquatic, Corbicula fluminea and biofilm carrier media显示文摘 | Hailiang SONG Xianning LI Wei LI Xiwu LU | 2014 | Frontiers of Environmental Science & Engineering2014，8，2： | 1 |
| 12 | An integrated ecological floating-bed employing plant, freshwater clam and biofilm cartier for purification of eutrophic water显示文摘 | LI Xiarming SONG Hailiang LI Wei | 2010 | Ecological Engineering2010，36，4： | 1 |
| 13 | Eco-water conveyances applied to control desertification at the lower reaches of the Tarim River显示文摘The lower reaches of the Tarim River are one of the areas suffering from most severe sandy desertification in Xinjiang, Northwest China. Irrational utilization of water and land resources results in eco-environmental deterioration in the Tarim River. In May 2000, the local government carried out the water conveyances project in the Tarim River. The influence of water conveyance on desertification reversion is analyzed and discussed according to the monitoring data in the past three years. Based on monitored data of the nine observed sections, along the channel of conveyance, the intensity and scope of desertification reversion in the upper reaches are larger than those in the lower reaches. Dynamic changes of desertification reversion are more obvious from the channel of conveyance to its two sides. However, the range of influence and intensity of desertification reversion is limited at present. It is suggested that the way and range of water conveyances should be adjusted in the future. | YE Mao XU Hailiang SONG Yudong | 2005 | Journal of Geographical Sciences2005，15，3： | 1 |
| 14 | The natural vegetation responses to the groundwater change resulting from ecological water conveyances to the lower Tarim River 显示文摘 | XU Hailiang YE Mao SONG Yudong | 2007 | Environ Monit Assess2007，131，： | 1 |
| 15 | An integratedecological floating-bed employing plant, freshwater clam andbiofilm carrier for purification of eutrophic water 显示文摘 | LI Xianning SONG Hailiang LI Wei | 2010 | EcologicalEngineering2010，36，4： | 1 |
| 16 | Ag Nanowire-Ag Nanoparticle Hybrids for the Highly Enhanced Fluorescene Detection of Protoporphyrin IX Based on Surface Plasmon-Enhanced Fluorescence显示文摘在这研究,我们开发了一条途径基于表面为 protoporphyrin IX (PpIX ) 的提高的 fluorescene 察觉制作新奇 1D Ag NWs-Ag NP 混合底层提高电浆子的荧光。Ag NWs-Ag NP 混血儿被联合热水的方法综合并且自己组装有 polyvinylpyrrolidone (PVP ) 的 asisstance 的方法。当 Ag NWs-Ag NP 混血儿在玻璃底层上被扔并且作为活跃底层采用了检测 PpIX 时, PpIX 的荧光紧张由于局部性的表面的联合效果极大地被提高电浆子局部性的表面电浆子( LSP-LSP )和导致了电磁的地的大改进的局部性的表面电浆子表面电浆子繁殖( LSP-SPP )。而且,当 PpIX 的集中从 1 ×10 −7 mol/L 被变化到 2 ×10 −5 mol/L,和 PpIX 的 photobleaching 现象时,改进效果是近似线性的极大地被减少,显示制作 Ag NWs-Ag NP 混合底层为 PpIX 成像有性能很好。这个工作提供一条有效途径准备高度敏感、稳定的荧光改进底层,并且在荧光成像有大潜在的申请。 | Yunjia Wang Xihong Zu Guobin Yi Hongsheng Luo Hailiang Huang Xuliang Song | 2016 | Chinese Journal of Chemistry2016，34，12： | 1 |
| 17 | The natural vegetation responses to the groundwater change resulting from ecological water conveyances to the lower Tarim River显示文摘 | Xu Hailiang Ye Mao Song Yudong | 2007 | Environmental Monitoring and Assessment2007，131，1： | 1 |
| 18 | A biomimetic antitumor nanovaccine based on biocompatible calcium pyrophosphate and tumor cell membrane antigens显示文摘Currently,the cancer immunotherapy has made great progress while antitumor vaccine attracts substantial attention.Still,the selection of adjuvants as well as antigens are always the most crucial issues for better vaccination.In this study,we proposed a biomimetic antitumor nanovaccine based on biocompatible nanocarriers and tumor cell membrane antigens.Briefly,endogenous calcium pyrophosphate nanogranules with possible immune potentiating effect are designed and engineered,both as delivery vehicles and adjuvants.Then,these nanocarriers are coated with lipids and B16-OVA tumor cell membranes,so the biomembrane proteins can serve as tumor-specific antigens.It was found that calcium pyrophosphate nanogranules themselves were compatible and possessed adjuvant effect,while membrane proteins including tumor associated antigen were transferred onto the nanocarriers.It was demonstrated that such a biomimetic nanovaccine could be well endocytosed by dendritic cells,promote their maturation and antigen-presentation,facilitate lymph retention,and trigger obvious immune response.It was confirmed that the biomimetic vaccine could induce strong T-cell response,exhibit excellent tumor therapy and prophylactic effects,and simultaneously possess nice biocompatibility.In general,the present investigation might provide insights for the further design and application of antitumor vaccines. | Minghui Li Mengmeng Qin Ge Song Hailiang Deng Dakuan Wang Xueqing Wang Wenbing Dai Bing He Hua Zhang Qiang Zhang | 2021 | Asian Journal of Pharmaceutical Sciences2021，16，1： | 1 |
| 19 | Estrogen removal from treated municipal effluent in small-scale constructed wetland with different depth 显示文摘 | SONG Hailiang NAKANO K TANIGUCHI T | 2009 | Bioresource Technology2009，100，12： | 1 |
| 20 | Improved Gossypium raimondii genome using a Hi-C-based proximity-guided assembly显示文摘Introduction:Genome sequence plays an important role in both basic and applied studies.Gossypium raimondii,the putative contributor of the D subgenome of upland cotton(G.hirsutum,highlights the need to improve the genome quality rapidly and efficiently.Methods:We performed Hi-C sequencing of G.raimondii and reassembled its genome based on a set of new Hi-C data and previously published scaffolds.We also compared the reassembled genome sequenee with the previously published G raimondii genomes for gene and genome sequence collinearity.Result:A total of 9842%of scaffold sequences were clustered successfully,among which 99.72%of the clustered sequences were ordered and 99.92%of the ordered sequences were oriented with high-quality.Further evaluation of results by heat-map and collinearity analysis revealed that the current reassembled genome is significantly improved than the previous one(Nat Genet 44:98-1103,2012).Conclusion:This improvement in G raimondii genome not only provides a better reference to increase study efficiency but also offers a new way to assemble cotton genomes.Furthermore,Hi-C data of G.raimondii may be used for 3D structure research or regulating analysis. | YANG Qiuhong ZUO Dongyun CHENG Hailiang ZHANG Youping WANG Qiaolian JAVARIA Ashraf FENG Xiaoxu LI Simin CHEN Xiaoqin LIU Shang SONG Guoli | 2021 | Journal of Cotton Research2021，4，3： | 0 |
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