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1篇 您的检索式:作者名="Haineng Huang"
    题名 作者 年代 出处 被引量
1Correlation between synaptic protein expression and synaptic reorganization in the hippocampal CA3 region in a rat model of post-traumatic epilepsy显示文摘Postsynaptic density protein-95 and synaptophysin participate in synaptic reorganization in the forebrain of epilepsy models.However,the time-effect relationship between dynamic synapsin expression in hippocampus and synaptic reorganization in the post-traumatic epilepsy model remains unclear.FeCl2 was injected into the hippocampal CA3 region of the right forebrain in rats to induce post-traumatic epilepsy.Postsynaptic density protein-95 and synaptophysin expression was detected using immunohistochemistry.Epileptiform discharge induced by FeCl2 injection was determined in rat forebrain neurons,revealing decreased postsynaptic density protein-95 expression at 24 hours and lowest levels at 7 days.Synaptophysin expression was markedly reduced at 24 hours,but increased at 7 days.Postsynaptic density protein-95 and synaptophysin expression was consistent with abnormal mossy fiber sprouting and synaptic reorganization following neuronal injury in the hippocampal CA3 region of FeCl2-induced epilepsy models.Gaolian Zhang Jianmin Huang Bang Zhao Haineng Huang Yuanyang Deng HuadongHuang Qirong He Jianping Liang 2010Neural Regeneration Research2010,5,15:0
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