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97篇 您的检索式:作者名="Hajduch"
    题名 作者 年代 出处 被引量
1Defect of insulin signal in peripheral tissues: important role of ceramide显示文摘In healthy people,balance between glucose production and its utilization is precisely controlled.When circulating glucose reaches a critical threshold level,pancreaticβcells secrete insulin that has two major actions:to lower circulating glucose levels by facilitating its uptake mainly into skeletal muscle while inhibiting its production by the liver.Interestingly,dietary triglycerides are the main source of fatty acids to fulfill energy needs of oxidative tissues.Normally,the unconsumed fraction of excess of fatty acids is stored in lipid droplets that are localized in adipocytes to provide energy during fasting periods.Thus,adipose tissue acts as a trap for fatty acid excess liberated from plasma triglycerides.When the buffering action of adipose tissue to store fatty acids is impaired,fatty acids that build up in othertissues are metabolized as sphingolipid derivatives such as ceramides.Several studies suggest that ceramides are among the most active lipid second messengers to inhibit the insulin signaling pathway and this review describes the major role played by ceramide accumulation in the development of insulin resistance of peripherals tissues through the targeting of specific proteins of the insulin signaling pathway.Rima Hage Hassan Olivier Bourron Eric Hajduch 2014World Journal of Diabetes2014,5,3:5
2Protein kinase C isoforms: Mediators of reactive lipid metabolites in the development of insulin resistance显示文摘Sophie Turban Eric Hajduch 2010FEBS Letters2010,,2:2
3Pharmacological activities of natural triterpenoids and their therapeutic implications显示文摘Dzubak P Hajduch M Vydra D 2006Nat Prod Rep2006,23,:1
4Cholesterol-induced caveolin targeting to lipid droplets in adipocytes:a role for caveolar endocytosis显示文摘Le Lay S Hajduch E Lindsay M R 2006Traffic2006,7,5:1
5New insights into ER stress-induced insulin resistance显示文摘Flamment M Hajduch E Ferre P 2012Trends Endocrinol Metab2012,23,8:1
6Hepatocellular carinoma:as- sessment of response to transarterial chemoembolization with image subtraction 显示文摘Kim S Mannelli L HajduCH 2010MagnReson Imaging2010,31,:1
7Proteomic comparison of virulent phase Ⅰ and avirulent phase Ⅱ of Coxiella burnetii, the causative agent of Q fever显示文摘Skultety L Hajduch M Flores-Ramirez G 2011Journal of Proteomics2011,74,10:1
8prostate cancer and the food supplement,PC-SPES显示文摘Thomson JO Dzubak P Hajduch M 2002Neoplasma2002,49,:1
9Transient aplastic crisis in a leukemic child caused by parvovirus B19 infection 显示文摘Mihal V Dusek J Hajduch M 1996Pediatr Hematol Oncol1996,13,2:1
10Insulin regulates the expression of the GLUT5 transporter in L6 skeletal muscle cells显示文摘Hajduch E Litherland G J Turban S 2003FEBS Lett2003,549,13:1
11Airborne high-resolution ISAR imaging of ship targets at sea 显示文摘Hajduch G Caillec J Garello R 2004IEEE Transaction on Aero space and Electronic Systems2004,40,1:1
12Fructose uptake in rat adipocytes:GLUT5 expression and the effects of streptozotocin-induced diabetes显示文摘Hajduch E Darakhshan F Hundal H S 1998Diabetologia1998,41,7:1
13Long term follow up of neoadjuvant adjuvant combination treatment of ⅢA stage non small cell lung cancer: results of neoadjuvant carboplatin/vinorelbine and carboplatin/paclitaxel regimens combined with selective adjuvant chemotherapy according to in vitro chemoresistance test显示文摘Kolek V Grygarkova I Hajduch M 2008Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub2008,152,25:1
14Cholesterol-induced caveolin targeting to lipid droplets in adipocytes:a role for caveolar endocytosis显示文摘Le Lay S Hajduch E Lindsay MR 2006Traffic2006,7,5:1
15MicroRNAs and glioblastoma: roles in core signalling pathways and potential clinical implications 显示文摘Sana J Hajduch M Michalek J 2011J Cell Mol Med2011,15,8:1
16Activation of glucose transport by AMP-activated protein kinase via stimulation of nitric oxide synthetase显示文摘Fryer LGD Hajduch E Rencurel F 2000Diabetes2000,49,:1
17Recent de- velopments in detection, imaging and classificcation for air- borne maritime surveillance显示文摘BON N HAJDUCH G KHENCHAF A 2008lET Signal Process2008,2,3:1
18Airborne high-resolution ISAR imaging of ship targets at sea显示文摘Hajduch G Lecaillec J M Garello R 2004IEEE Transactions on Aerospace and Electronic Systems2004,40,1:1
19Airborne High-Resolution ISAR Imaging of Ship Targets at Sea显示文摘Hajduch G Caillec J M LE Garello R 2004IEEE Trans on AES2004,40,1:1
20Cholesterol-induced caveolin targeting to lipid droplets in adipocytes:a role for caveolar endocytosis显示文摘Le Lay S Hajduch E Lindsay MR 0,,:1
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