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| 1 | Multiple amino acid sensing inputs to mTORC1显示文摘rapamycin 建筑群 1 的 evolutionarily 保存的目标(TORC1 ) 是细胞生长和新陈代谢的一个主人管理者。在哺乳动物,生长因素和细胞的精力通过 TSC 建筑群(TSC1-TSC2-TBC1D7 ) 的抑制刺激 mTORC1 活动, mTORC1 的一个否定管理者。氨基酸独立于 TSC 建筑群发信号到 mTORC1。这里,我们考察连接氨基酸充足到 mTORC1 活动的最近识别的管理者并且影响这些管理者的变化怎么引起人的疾病。 | itsugu Shimobayashi Michael N Hall | 2016 | Cell Research2016，26，1： | 10 |
| 2 | 胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。 | Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 3 | mTOR signaling in disease显示文摘 | Eva Dazert Michael N Hall | 2011 | Current Opinion in Cell Biology2011，，6： | 2 |
| 4 | Magnetic resonance imaging in the assessment of complex mullerian anomalies显示文摘 | Minto CL Hollings N Hall Craggs M | 2000 | BJOG2000，108，8： | 1 |
| 5 | Smote: Synthetic Minority Over-sampling Technique显示文摘 | Chawla N V Bower K W Hall L O | 2002 | Journal of Artificial Intelligence Research2002，16，3： | 1 |
| 6 | Urinary intestinal fatty acid - binding protein concentration predicts extent of disease in neerotizing enterocolitis 显示文摘 | Evennett N J Hall N J Pierro A | 2010 | J Pediatr Surg2010，45，4： | 1 |
| 7 | Recent developments in inductively coupled plasma magnetic sector multiple collector mass spectrometry 显示文摘 | Halliday A N Lee D C Christensen J N Walder A J Freedman P A Jones C E Hall C M Yi W Teagle D | 1995 | Int J Mass Spec Ion Proc1995，，： | 1 |
| 8 | Techniques for the sputtering of optimum indium-tin oxide films on to room-temperature substrates显示文摘 | Danson N Safi I Hall G W | 1998 | Surface & Coatings Technology1998，99，12： | 1 |
| 9 | Multiphoton imaging reveals differences in mitochondrial function between nephron segments显示文摘 | Hall AM Unwin RJ Parker N | 2009 | J Am Soc Nephrol2009，20，6： | 1 |
| 10 | Maximizing the value of a space mission显示文摘 | Hall N G Magazine M J | 1994 | European Journal of Operational Research1994，78，2： | 1 |
| 11 | Biosensing with plasmonic nanosensors显示文摘 | ANKER J N HALL W P LYANDRES O | 2008 | Nat Mater2008，7，6： | 1 |
| 12 | Upconverting phosphor reporters in immunoehromatographic assays 显示文摘 | Hampl J Hall M Mufti N A | 2001 | Anal Bio- ehem2001，288，2： | 1 |
| 13 | Effects of Cardiac Resynchronization on Disease Progression in Patients With Left Ventricular Systolic Dysfunction, an Indication for an Implantable Cardioverter-Defibrillator, and Mildly Symptomatic Chronic Heart Failure显示文摘 | William T. Abraham James B. Young Angel R. León Stuart Adler Alan J. Bank Shelley A. Hall Randy Lieberman L Bing Liem John B. O’Connell John S. Schroeder Kevin R. Wheelan | 2004 | Circulation2004，，18： | 1 |
| 14 | Rescheduling for new orders显示文摘 | Hall N G Potts C N | 2004 | Operations Research2004，52，3： | 1 |
| 15 | Supply chain scheduling:batching and delivery显示文摘 | Hall N G Potts C N | 2003 | Operations Research2003，51，4： | 1 |
| 16 | Nitrogen oxide emissions after nitrogen addition in tropical forests显示文摘 | Hall S J Dise N B Mountford J O | 1999 | Nature1999，，400： | 1 |
| 17 | Supply chain scheduling: Batehing and delivery 显示文摘 | HALL N G POTTS C N | 2003 | Operations Research2003，51，： | 1 |
| 18 | TOR, a central controller of cell growth 显示文摘 | Schmelzle T Hall M N | 2000 | Cell2000，103，2： | 1 |
| 19 | Wet Strength Chemistry显示文摘 | Dunlop-Jones N Roberts Chapman J C Hall | 1991 | Paper Chemistry1991，，6： | 1 |
| 20 | Near infrared reflectance prediction of quality, theaflavin content and moisture content of black tea显示文摘 | M N Hall A Robertson C N G Scotter | 1988 | Food Chem1988，，27： | 1 |
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