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| 1 | 急性脊髓损伤患者治疗的临床操作指南:关于MRI基线在临床治疗决策与结果预测中作用的几点建议(英文)显示文摘The objective of this guideline is to outline the role of magnetic resonance imaging(MRI) in clinical decision making and outcome prediction in patients with traumatic spinal cord injury(SCI).Methods A systematic review of the literature was conducted to address key questions related to the use of MRI in patients with traumatic SCI.This review focused on longitudinal studies that controlled for baseline neurologic status.A multidisciplinary Guideline Development Group(GDG) used this information,their clinical expertise,and patient input to develop recommendations on the use of MRI for SCI patients.Based on GRADE(Grading of Recommendation,Assessment,Development and Evaluation),a strong recommendation is worded as ' we recommend,' whereas a weaker recommendation is indicated by 'we suggest.' Results Based on the limited available evidence and the clinical expertise of the GDG,our recommendations were:(1) 'We suggest that MRI be performed in adult patients with acute SCI prior to surgical intervention,when feasible,to facilitate improved clinical decision-making'(quality of evidence,very low) and(2) 'We suggest that MRI should be performed in adult patients in the acute period following SCI,before or after surgical intervention,to improve prediction of neurologic outcome '(quality of evidence,low).Conclusions These guidelines should be implemented into clinical practice to improve outcomes and prognostication for patients with SCI. | Fehlings MG Martin AR Tetreault LA Aarabi B Anderson P Arnold PM Brodke D Burns AS Chiba K Dettori JR Furlan JC Hawryluk G Holly LT Howley S Jeji T Kalsi-Ryan S Kotter M Kurpad S Kwon BK Marino RJ Massicotte E Merli G Middleton JW Nakashima H Nagoshi N Palmieri K Singh A Skelly AC Tsai EC Vaccaro A Wilson JR Yee A Harrop JS | 2017 | 中华神经外科疾病研究杂志2017，16，6： | 8 |
| 2 | 血流介导的血管舒张,硝酸甘油诱导的血管舒张,基线肱动脉直径,充血剪切应力与心血管病危险因素之间的相关性显示文摘血流介导的血管舒张功能(flow-mediated vasodilation,FMD)已被用于评估内皮功能。充血性剪切应力(hyperemic shear stress,HSS,一种FMD的刺激因素)、硝酸甘油诱导的血管舒张(nitroglycerine-induced vasodilation,NID,非内皮依赖性血管舒张指数)以及基线肱动脉直径(brachial artery diameter,BAD)也参与血管舒张反应。 | 刘青 叶鹏 Maruhashi T Iwamoto Y Kajikawa M Oda N Kishimoto S Matsui S Hashimoto H Aibara Y Yusoff FM Hidaka T Kihara Y Chayama K Noma K Nakashima A Goto C Hida E Higashi Y | 2018 | 中华高血压杂志2018，26，1： | 5 |
| 3 | 胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。 | Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 4 | Tympanometric findinss in patients with enlarged vestibular aqueducts 显示文摘 | Sato E Nakashima T Lilly DJ | 2002 | Laxyngoscope2002，112，： | 1 |
| 5 | Effects of age at menopause on serum cholesterol,body mass index,and blood pressure显示文摘 | Akahoshi M Soda M Nakashima E | 2001 | Atherosclerosis2001，156，： | 1 |
| 6 | 2 - 显示文摘 | Shibata S Kamata E Nakashima R | 1976 | Analytical Chimica Acta1976，82，： | 1 |
| 7 | Cell fusion-independent differentiation of neural stem cells to the endothelial lineage显示文摘 | Nakashima K Summers RG | 2004 | Nature2004，430，6997： | 1 |
| 8 | Overexpression of metadherin/MTDH is associated with an aggressive phenotype and a poor prognosis in invasive breast cancer 显示文摘 | TOKUNAGA E NAKASHIMA Y YAMASHITA N | 2014 | Breast Cancer2014，21，3： | 1 |
| 9 | Evidence for osteocyte regulation of bone homeostasis through RANKL expression显示文摘 | Nakashima T Hayashi M Fukunaga T Kurata K Oh-Hora M Feng J Q B onewald L F K odama T W utz A W agner E F Penninger JM Takayanagi H | | 0，，： | 1 |
| 10 | Heat transfer in a twin-screw multiphase pump:thermal modeling and one application in the petroleum industry 显示文摘 | Nakashima Celso Y Jr Silvio de Oliveira Caetano E F | 2006 | Energy2006，31，15： | 1 |
| 11 | Visceral and peripheral arterial pseudoaneurysms显示文摘 | Sueyoshi E Sakamoto I Nakashima K | 2005 | Am J Roentgenol2005，185，3： | 1 |
| 12 | Heat transfer in a twin-screw multiphase pump:Thermal modeling and one application in the petroleum industry显示文摘 | NAKASHIMA C Y OLIVEIRA S D CAETANO E F | 2006 | Energy2006，31，15： | 1 |
| 13 | Cell fusionindependent differentiation of neural stem cells to the endothelial lineage显示文摘 | Wurmser A E Nakashima K Summers R G | | 0，，6997： | 1 |
| 14 | Molecular cloning of a gene encoding a new type of met alloproteinase-disintegrin family protein with thrombospondin motifs as an inflammation associated gene显示文摘 | Kanada N Nakashima E | 1997 | J Biol Chem1997，272，1： | 1 |
| 15 | Development of real- time pseudodynamic testing 显示文摘 | Nakashima M Kato H Takaoka E | 1992 | Earthquake Engineering and Structural Dynamics1992，21，1： | 1 |
| 16 | Synthesis and biological activity of 1-methyl-tryptophan- tirapazamine hybrids as hypoxia-targeting indoleaine 2,3-dioxygenase inhibitors 显示文摘 | NAKASHIMA H UTO Y NAKATA E | 2008 | Bioorg Med Chem2008，16，18： | 1 |
| 17 | ApoE-de- ficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree 显示文摘 | Nakashima Y Plump A S Raines E W | 1994 | Arterioscler Thromb1994，14，1： | 1 |
| 18 | Relationships in the structure-tissue distribution of basic drugs in the rabbit显示文摘 | YOKOGAWA K NAKASHIMA E ISHIZAKI J | 1990 | Pharm Res1990，7，7： | 1 |
| 19 | Sensitivity enhancement of solid-state NMR spectra of half-integer spin quadrupolar nuclei using hyperbolic secant pulses:Applications to spin-5/2 nuclei显示文摘 | Siegel R Nakashima T T Wasylishen R E | 2006 | Chem Phys Lett2006，421，： | 1 |
| 20 | Crystal structure of bacterial multidrug efflux transporter AcrB显示文摘 | Murakami S Nakashima R Yamashita E | 2002 | Nature2002，419，6907： | 1 |
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