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19篇 您的检索式:作者名="Kawashiri MA"
    题名 作者 年代 出处 被引量
1胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 2017中华高血压杂志2017,25,9:2
2In vivo mod- ulation of HDL phospholipid has opposing effects on SR- BI-and ABCAl-mediated cholesterol efflux 显示文摘Yancey PG Kawashiri MA Moore R 2004J Lipid Res2004,45,:1
3In vivo modulation of HDL phospholipid had opposing effects on SR-BI and ABCAl-mediated cholesterol efflux显示文摘Yancey PG Kawashiri MA Moore R 2004J Lipid Res2004,45,2:1
4Combined efects of cholesterol reduction and apolipoprotein A-1 expression on atherosclerosis in LDL receptor deficient mice显示文摘Kawashiri MA Zhang Y Pure E 2002Atheroscleosis2002,165,1:1
5Comparison of effects of pitavastatin and atorvastatin on plasma coenzyme Q10 in heterozygous familial hypercholesterolemia:results from a crossover study显示文摘Kawashiri MA Nohara A Tada H 0,,05:1
6In vivo modulation of HDL phospholipid has opposing effects on SR-BI-and ABCA1-mediated cholesterol efflux显示文摘Yancey PG Kawashiri MA Moore R Glick JM Williams DL Connelly MA 2004J Lipid Res2004,45,2:1
7显示文摘 Inazu A Kawashiri MA 2003Am J Physiol Endocrinol Metab2003,25,:1
8Impact of severe earthquake on the occurrence of acute coronary syndrome and stroke in a rural area of Japan显示文摘Tsuchida M Kawashiri MA Teramoto R 2009Cite J2009,73,7:1
9Comparison of effects of pitavastatin and atorvastatin on plasma coenzyme Q10 in heterozygous familial hypercholesterolemia: Results from a crossover study 显示文摘Kawashiri Ma Nohara A Tada H 2008Clinical Pharmacology 8< Therapeutics2008,83,:1
10In vivo modulation of HDL phospholipid has opposing effects on SR-BI-and ABCA1-mediated cholesterol efflux显示文摘Yancey PG Kawashiri MA Moore R 0,,02:1
11In vivo modulation of HDL phospholipid has opposing effects on SR-BI-and ABCA1-mediated cholesterol efflux显示文摘Yancey PG Kawashiri MA Moore R 2004J Lipid Res2004,45,:1
12Circulating matrix metallopmteinases and their inhibitors in premature coronary atheroselerosis 显示文摘Noji Y Kajinami K Kawashiri MA 2001Clin Chem lab Med2001,39,5:1
13Comparison of effects of pitavastatin and atorvastatin on plasma coenzyme Q10in heterozygous familial hypercholesterolemia:results from a crossover study显示文摘Kawashiri MA Nohara A Tada H 2008Clin Pharmacol Ther2008,83,5:1
14Matrix metalloproteinases and their inhibitors in premature coronary atherosclerosis显示文摘Noji Y Kajinami K Kawashiri MA 2001Clin Chem Lab Med2001,39,5:1
15High-density lipoprotein metabolism:molecular targets for new therapies for atherosclerosis显示文摘 Maugeais C Rader DJ 2000Curr Atheroscler Rep2000,2,:1
16Circulating matrix metalloproteinases and their inhibitors in premature coronary atherosclerosis显示文摘Noji Y Kajinami K Kawashiri MA 2001Clin Chem Lab Med2001,39,5:1
17The E32K variant of PCSK9 excerbates the phenotype of familial hypercholesterolaemia by increasing PCSK9 function and concentration in the circulation 显示文摘Noguchi T Katsuda S Kawashiri MA 2010Atherosclerosis2010,210,1:1
18Combined effects of cholesterol reduction and apolipoprotein A-1 expression on atherosclerosis in LDL receptor deficient mice显示文摘Kawashiri MA Zhang Y Pure E Rader DJ 2002Atherosclerosis2002,165,1:1
19Comparison of effects of pitavastatin and atorvastatin on plasma coenzyme QIO in heterozygous familial hypercholesterolemia: results from a crossover study显示文摘Kawashiri MA Nohaxa A Tada H 2008Clin Pharmacol Ther2008,83,5:1
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