|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Stroke mechanisms and outcomes of isolated symptomatic basilar artery stenosis显示文摘background While diffuse atherosclerotic disease affecting the posterior circulation has been described extensively,the prevalence,natural history and angiographic characteristics of isolated symptomatic basilar artery stenosis(ISBAS)remain unknown.Methods We reviewed our prospective institutional database to identify patients with≥50% symptomatic basilar artery(BA)stenosis without significant atherosclerotic burden in the vertebral or posterior cerebral arteries.Stroke mechanism,collateral circulation,and degree and length of stenosis were analysed.The primary outcome was time from index event to new transient ischaemic attack(TIA),acute ischaemic stroke(AIS)or death.Other outcome variables included modified Rankin Scale(mRS)score on discharge and last follow-up.results Of 6369 patients with AIS/TIA,91(1.43%)had ISBAS.Seventy-three(80.2%)patients presented with AIS and 18(19.8%)with TIA.Twenty-nine(31.9%)were women and the median age was 66.8±13.6 years.The mean follow-up time was 2.7 years.The most common stroke mechanism was artery-to artery thromboembolism(45.2%),followed by perforator occlusion(28.7%)and flow-dependent/hypoperfusion(15.1%).The percentage of stenosis was lower in patients who had favourable outcome compared with those with mRS 3-6 on discharge(78.3±14.3 vs 86.9±14.5,p=0.007).Kaplan-Meier curves showed higher recurrence/death rates in patients with≥80% stenosis,mid-basilar location and poor collateral circulation.Approximately 13% of patients with ISBAS presented with complete BA occlusion.Conclusion ISBAS is an uncommon(1.43%)cause of TIA and AIS.Men in their 60s are mostly affected,and artery-to artery embolism is the most common stroke mechanism.Mid-basilar location,≥80% stenosis and poor collateral circulation are important factors associated with worse prognosis. | Edgar A Samaniego Amir Shaban Santiago Ortega-Gutierrez Jorge A Roa David M Hasan Colin Derdeyn Biyue Dai Harold Adams Enrique Leira | 2019 | Stroke & Vascular Neurology2019，4，4： | 10 |
| 2 | 直接评估吗啡刺激糖尿病人隐静脉内皮一氧化氮释放减少显示文摘to directly measure in real time basal and stimulated levels of NO released from human saphenous vein endothelium and to quantify the expression of the μopiate receptor, which has been linked with NO release. METHODS: Saphenous vein segments from patients with type 2 diabetes ( n = 12) and patients without diabetes (n =8) were obtained. The release of NO was measured directly from the endothelium using a NO-specific amperometric probe. NΩ-nitro-L-arginine methyl ester (L-NAME, 0.1 mmol/L), a NO synthase (NOS) inhibitor, or morphine (1 μmol/L), a stimulant, was administered and the measurements were repeated. Values were reported relative to the mean initial measurement of NO release from diabetic endothelium, which was defined as the relative zero level of NO release. A RT-PCR was then performed on the endothelium to measureμ opiate receptor expression. RESULTS: Diabetic patients (n = 12) showed a relative and significantly diminished basal level of released NO, (0.049± 0.012) nmol/L, compared | Thomas V BILHNGER, James A VOSSWINKEL, Patrick CADET, Christos M RIALAS, Harold I MAGAZINE, George B STEFANO(Division of Cardiothoracic Surgery, Department of Surgery, University Hospital and Medical Center, HSC, T19-080, Stony Brook, New York 11794-8191 Neuroscience Research Institute, State University of New York College at Old Westbury, Old Westbury, New York , USA) | 2002 | Acta Pharmacologica Sinica2002，23，2： | 3 |
| 3 | Salpingotomy versus salpingectomy in women with tubal pregnancy (ESEP study): an open-label, multicentre, randomised controlled trial显示文摘 | Femke Mol Norah M van Mello Annika Strandell Karin Strandell Davor Jurkovic Jackie Ross Kurt T Barnhart Tamer M Yalcinkaya Harold R Verhoeve Giuseppe C M Graziosi Carolien A M Koks Ingmar Klinte Lars Hogstr?m Ineke C A H Janssen Harry Kragt Annemieke Hoek | 2014 | The Lancet2014，，： | 2 |
| 4 | Comparison of the efficacy and safety of rosuvastatin versus atorvastatin , simvastatin , and pravastatin across doses (STELLAR * * STELLAR = Statin Therapies for Elevated Lipid Levels compared Across doses to Rosuvastatin. Trial)显示文摘 | Peter H Jones Michael H Davidson Evan A Stein Harold E Bays James M McKenney Elinor Miller Valerie A Cain James W Blasetto | 2003 | The American Journal of Cardiology2003，，2： | 2 |
| 5 | Acinetobacter calcoaceticus genes involved in biosynthesis of the coenzyme pyrrolo-quinoline-quinone:nuleotide sequence and expression in Escherichia coli K-12显示文摘 | Goosen N Harold P A H Rene G M H | 1989 | J Bacteriol1989，171，1： | 1 |
| 6 | Isolation of anticoag ulant fractions from crude fucoidin显示文摘 | Georg F S Harold A W George M | 1957 | Experimental Biology and Medicine1957，94，2： | 1 |
| 7 | Acoustic,aerodynamic,and perceptual analyses of the voice of cochlear-implanted children显示文摘 | HAROLD A GUERRERO L MICHEL M | 2013 | J Voice2013，27，： | 1 |
| 8 | Pletepol TGF-β stimulation and inhibition of cell proliferation: New Mechanistic Insights显示文摘 | Harold L M Edmund Y Y Jennifer A | 1990 | Cell1990，63，： | 1 |
| 9 | Four-port coupled channel-guide device based on 2D photonic crys- tal structure 显示文摘 | Edilson A C Harold M H C Richard M | 2004 | Photonics and Nanostructures2004，2，1： | 1 |
| 10 | Biochar: A Synthesis of Its Agronomic Impact beyond Carbon Sequestration显示文摘 | Spokas Kurt A Cantrell Keri B M Novak Jeffrey Archer David W Ippolito James A Collins Harold P Boateng Akwasi A Lima Isabel M Lamb Marshall C McAloon Andrew J Lentz Rodrick D Nichols Kristine A | 2012 | Journal of Environmental Quality2012，，4： | 1 |
| 11 | Pyrolytic carbon nanotubes from vapor- grown carbon fibers 显示文摘 | Endo M Takeuchi K Kobori K Katsushi T Harold W K Sarkar A | 1995 | Carbon1995，33，： | 1 |
| 12 | Comparing Acquisitions and Divestitures 显示文摘 | BOONE A L HAROLD M | 2000 | Journal of Corporate Finance2000，，6： | 1 |
| 13 | Performance of flax eultivars in response to exogenous application of salicylic acid under salinity stress 显示文摘 | Ebtihal M El - Harold A Sadak M S | 2012 | Journal of Applied Sciences Research2012，8，10： | 1 |
| 14 | Pulmonary hypertension in patients with chronic renal failure:role of parathyroid hormone mad pulmonary artery calcifications显示文摘 | Amin M Fawzy A Harold MA | 2003 | Chest2003，124，： | 1 |
| 15 | Comparison of the efficacy and safety of rosuvastatin versus atorvastatin , simvastatin , and pravastatin across doses (STELLAR * * STELLAR = Statin Therapies for Elevated Lipid Levels compared Across doses to Rosuvastatin. Trial)显示文摘 | Peter H Jones Michael H Davidson Evan A Stein Harold E Bays James M McKenney Elinor Miller Valerie A Cain James W Blasetto | 2003 | The American Journal of Cardiology2003，，2： | 1 |
| 16 | The biochemistry of tea fermentation:oxidative degallation and epimerization of the tea flavanol gallates 显示文摘 | Philip C Gerald A M Harold N G | 1973 | Agr Food Chem1973，21，： | 1 |
| 17 | Human domination of earth's ecosystems显示文摘 | Peter M Vitousek Harold A Mooney Jane Lubchenco | 1997 | Science1997，277，： | 1 |
| 18 | Copper matrix SiC and Al2O3 particulate composites by powder metallurgy technique 显示文摘 | Moustafa S F Abdel Harold A Abd Elhay A M | 2002 | Materials Let ters2002，53，： | 1 |
| 19 | Prospective evaluation of relatives for familial arrhythmogenic right ventricular cardiomyopathy/dysplasia reveals a need to broaden diagnostic criteria显示文摘 | Harold MS Norman M Quraishi A | 2002 | J Am Coll Cardiol2002，40，8： | 1 |
| 20 | Methods of sputum processing for cell counts, im-munocytochemistry and in situ hybridization 显示文摘 | Efthimiadis A Spanevello A Harold Q Kelly MM Linden M Louis R | 2002 | Eur Respir J Suppl2002，20，37： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员