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| 1 | Comparison of multichannel intraluminal impedance-pH monitoring and reflux scintigraphy in pediatric patients with suspected gastroesophageal reflux显示文摘AIM To evaluate the agreement of multichannel intraluminal impedance-p H monitoring(MII-p HM) and gastroesophageal reflux scintigraphy(GES) for the diagnosis of gastroesophageal reflux disease. METHODS Seventy-five consecutive patients with suspectedgastroesophageal reflux disease(GERD) underwent 24-h combined MII-p HM recording and one hour radionuclide scintigraphy during the course of the MIIpH M study. Catheters with 6 impedance channels and 1 p H sensor were placed transnasally. Impedance and p H data analysis were performed automatically and manually. For impedance monitoring, reflux was defined as a retrograde 50% drop in impedance, starting distally and propagating retrogradely to at least the next two more proximal measuring channels. Reflux index(RI, percentage of the entire record that esophageal p H is < 4.0) greater than 4.2% for p HM and number of refluxes more than 50 for 24 h for MII were accepted as positive test results. At scintigraphy, 240 frames of 15 seconds duration were acquired in the supine position. Gastroesophageal reflux was defined as at least one reflux episode in the esophagus. After scintigraphic evaluation, impedance-pH recordings and scintigraphic images were evaluated together and agreement between tests were evaluated with Cohen's kappa.RESULTS Sufficient data was obtained from 60(80%) patients(34 male, 56.7%) with a mean age of 8.7 ± 3.7 years(range: 2.5-17.3 years; median: 8.5 years). Chronic cough, nausea, regurgitation and vomiting were the most frequent symptoms. The mean time for recording of MII-pH M was 22.8 ± 2.4 h(range: 16-30 h; median: 22.7 h). At least one test was positive in 57(95%) patients. According to diagnostic criteria, GERD was diagnosed in 34(57.7%), 44(73.3%), 47(78.3%) and 51(85%) patients by means of p HM, MII, GES and MII-p HM, respectively. The observed percentage agreements/κ values for GES and p HM, GES and MII, GES and MII-p HM, and MII and p HM are 48.3%/-0.118; 61.7%/-0.042; 73.3%/0.116 and 60%/0.147, respectively. There was no or slight agreement between GES and p HM alone, MII alone or MII-p HM. p H monitoring alone missed 17 patients compared to combined MII-p HM. The addition of MII to pH monitoring increased the diagnosis rate by 50%.CONCLUSION No or slight agreement was found among p H monitoring, MII monitoring, MII-pH monitoring and GES for the diagnosis of gastroesophageal reflux disease. | Nuray Uslu Kizilkan Murat Fani Bozkurt Inci Nur Saltik Temizel Hülya Demir Aysel Yüce Biray Caner Hasan Ozen | 2016 | World Journal of Gastroenterology2016，22，43： | 2 |
| 2 | Reticulated platelet levels in patients with ulcerative colitis显示文摘 | Hasan Kayahan Mesut Akarsu Mehmet Ali Ozcan Serdal Demir Halil Ates Belkis Unsal Hale Akpinar | 2007 | International Journal of Colorectal Disease2007，，12： | 2 |
| 3 | Joint source/channel coding for variable length codes 显示文摘 | SAYOOD K HASAN H DEMIR N | 2000 | IEEE Trans Commun2000，48，5： | 1 |
| 4 | Joint Source/Channel Coding for Variable Length Codes显示文摘 | Khalid Sayood Hasan H Out Nejat Demir | 2000 | IEEE Trans On Comm2000，48，5： | 1 |
| 5 | Quadruple Thinking: Hopeful Thinking显示文摘 | Sinem Tarhan Hasan Bacanl? Mehmet Ali Dombayc? Metin Demir | 2011 | Procedia - Social and Behavioral Sciences2011，，： | 1 |
| 6 | Use of CA - 125 fluctuation during the menstrual cycle as tool in the clinical diagnosis of endometriosis: a preliminary report显示文摘 | HASAN KAFALI HULYA ARTUC NURETTIN DEMIR | 2004 | European Journal of Obstetrics Gynecology and Re - productive Biology2004，116，： | 1 |
| 7 | A review on adsorption heat pump:Problems and solutions 显示文摘 | Hasan Demir Mogbtada Mobedi Semra Ulku | 2008 | Renewable and Sustainable Energy Reviews2008，，12： | 1 |
| 8 | Evaluation of carotid intima-media thickness and carotid arterial stiffness in children with adenotonsillar hypertrophy显示文摘Background:Adenotonsillar hypertrophy can produce cardiopulmonary disease in children.However,it is unclear whether adenotonsillar hypertrophy causes atherosclerosis.This study evaluated carotid intimamedia thickness and carotid arterial stiffness in children with adenotonsillar hypertrophy.Methods:The study included 40 children with adenotonsillar hypertrophy(age:5-10 years)and 36 healthy children with similar age and body mass index.Systolic blood pressure,diastolic blood pressure,and pulse pressure were measured in all subjects.Carotid intima-media thickness,carotid arterial systolic diameter,and carotid arterial diastolic diameter were measured using a high-resolution ultrasound device.Based on these measurements,carotid arterial strain,carotid artery distensibility,beta stiffness index,and elasticity modulus were calculated.Results:Carotid intima-media thickness was greater in children with adenotonsillar hypertrophy(0.36±0.05 mm vs.0.34±0.04 mm,P=0.02)compared to healthy controls.Beta stiffness index(3.01±1.22 vs.2.98±0.98,P=0.85),elasticity modulus(231.39±99.23 vs.226.46±83.20,P=0.88),carotid arterial strain(0.17±0.06 vs.0.17±0.04,P=0.95),and carotid artery distensibility(13.14±3.88 vs.12.92±3.84,P=0.75)were similar between children with adenotonsillar hypertrophy and the healthy controls.Conclusions:The present study revealed increased carotid intima-media thickness in children with adenotonsillar hypertrophy.The risk of subclinical atherosclerosis may be higher in children with adenotonsillar hypertrophy. | MuratÇiftel Berrin Demir Günay Kozan Osman Yılmaz Hasan Kahveci Ömer Kılıç | 2016 | World Journal of Pediatrics2016，12，1： | 0 |
| 9 | Unfused Crossed Renal Ectopia with Nephrolithiasis Diagnosed Incidentally in Emergency Room显示文摘 | Mehmet Akeimen Tuba Cimilli Ozturk Hasan Demir Yalman Eyinc Halil Aliskan Ozge Ecmel Onur | 2014 | Journal of Health Science2014，2，6： | 0 |
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