|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Role of gastroesophageal reflux disease in lung transplantation显示文摘Lung transplantation is one of the highest risk solid organ transplant modalities. Recent studies have demonstrated a relationship between gastroesophageal reflux disease(GERD) and lung transplant outcomes, including acute and chronic rejection. The aim of this review is to discuss the pathophysiology, evaluation, and management of GERD in lung transplantation, as informed by the most recent publications in the field. The pathophysiology of reflux-induced lung injury includes the effects of aspiration and local immunomodulation in the development of pulmonary decline and histologic rejection, as reflective of allograft injury. Modalities of reflux and esophageal assessment, including ambulatory p H testing, impedance, and esophageal manometry, are discussed, as well as timing of these evaluations relative to transplantation. Finally, antireflux treatments are reviewed, including medical acid suppression and surgical fundoplication, as well as the safety, efficacy, and timing of such treatments relative to transplantation. Our review of the data supports an association between GERD and allograft injury, encouraging a strategy of early diagnosis and aggressive reflux management in lung transplant recipients to improve transplant outcomes. Further studies are needed to explore additional objective measures of reflux and aspiration, better compare medical and surgical antireflux treatment options, extend followup times to capture longer-term clinical outcomes, and investigate newer interventions including minimally invasive surgery and advanced endoscopic techniques. | Kelly E Hathorn Walter W Chan Wai-Kit Lo | 2017 | World Journal of Transplantation2017，7，2： | 8 |
| 2 | Role of endoscopic vacuum therapy in the management of gastrointestinal transmural defects显示文摘A gastrointestinal(GI) transmural defect is defined as total rupture of the GI wall,and these defects can be divided into three categories: perforations,leaks,and fistulas. Surgical management of these defects is usually challenging and may be associated with high morbidity and mortality rates. Recently,several novel endoscopic techniques have been developed,and endoscopy has become a firstline approach for therapy of these conditions. The use of endoscopic vacuum therapy(EVT) is increasing with favorable results. This technique involves endoscopic placement of a sponge connected to a nasogastric tube into the defect cavity or lumen. This promotes healing via five mechanisms,including macrodeformation,microdeformation,changes in perfusion,exudate control,and bacterial clearance,which is similar to the mechanisms in which skin wounds are treated with commonly employed wound vacuums. EVT can be used in the upper GI tract,small bowel,biliopancreatic regions,and lower GI tract,with variable success rates and a satisfactory safety profile. In this article,we review and discuss the mechanism of action,materials,techniques,efficacy,and safety of EVT in the management of patients with GI transmural defects. | Diogo Turiani Hourneaux de Moura Bruna Furia Buzetti Hourneaux de Moura Michael A Manfredi Kelly E Hathorn Ahmad N Bazarbashi Igor Braga Ribeiro Eduardo Guimaraes Hourneaux de Moura Christopher C Thompson | 2019 | World Journal of Gastrointestinal Endoscopy2019，11，5： | 6 |
| 3 | Flavor and antioxidant capacity of peanut paste and peanut butter supplemented with peanut skins显示文摘 | HATHORN C S SANDERS T H | 2012 | Journal of Food Science2012，77，11： | 1 |
| 4 | Detection of circulating candida enolase by immunoassay in patients with cancer and invasive candidiasis显示文摘 | Walsh TJ Hathorn JW Sobel JD | 1991 | N Engl J Med1991，324，5： | 1 |
| 5 | Thermal detection of cellular infiltrates in living atherosclerotic plaques: possible' implications for plaque rupture and thrombosis显示文摘 | Casscells W Hathorn B David M | 1996 | Lancet1996，347，9013： | 1 |
| 6 | Online collaboration:making it work显示文摘 | INGRAM A L | 2002 | Educational Technology2002，42，1： | 1 |
| 7 | Histochemical and chemical studies of calciferol-induced vascular injuries显示文摘 | Gillman T Grant RA Hathorn M | | 0，，： | 1 |
| 8 | Effects of different surgical regiments on nasal asymmetry and facial attractiveness in patients with clefts of the lip and palate显示文摘 | Roberts - Harry DP Evans R Hathorn IS | 1991 | Cleft Palate Craniofac J1991，28，： | 1 |
| 9 | Thermal detection of cellular infiltrates in living atherosclerotic plaques: possible implication for plaque rupture and thrombosis显示文摘 | Casell W Hathorn B David M | 1996 | Lancet1996，347，： | 1 |
| 10 | Stable Sr-isotope, Sr/Ca, Mg/Ca, Li/Ca and Mg/Li ratios in the scleractinian cold-water coral Lophelia pertusa显示文摘 | RADDATZ J LIEBETRAU V ROGGEBERG A HATHORNE E KRABBENHOFT A EISENHAUER A BOttM F VOLLSTAEDT H FIETZKE J LOPEZ CORREA M FREIWALD A DULLO W | 2013 | Chemical Geology2013，352，： | 1 |
| 11 | A multicenter, randomized trial of fluconazole versus amphotericin B for empiric antifungal therapy of febrile neutropenic patients with cancer 显示文摘 | Winston DJ Hathorn JW Schuster MG | 2000 | Am J Med2000，108，4： | 1 |
| 12 | Thermal detection of cellular infiltrates in living atherosclerotic plaques:possible implication for plaqure and thrombosis显示文摘 | Takano M Hathorn B David M | | The Lancet0，，： | 1 |
| 13 | Thermal detection of cellular infiltrates in living atherosclerotic plaques:possible implications for plaque rupture and thrombosis显示文摘 | Hathorn B David M | 1996 | Lancet1996，347，： | 1 |
| 14 | The GOSLON yardstick applied to a consecutive series of patients with unilateral clefts of the lip and palate显示文摘 | Hathorn I Harry-Roberts D Mars M | 1996 | Cleft Palate Craniofac1996，33，6： | 1 |
| 15 | Using EMG to Measure Knee Joint Forces 显示文摘 | Boolaky UV Bainbridge J Hathorn I | 2001 | Journal of Bone and Joint Surgery-British Volume2001，83，： | 1 |
| 16 | Using EMG to measure knee joint forces 显示文摘 | Boolaky UV Bainbridge J Hathorn I | 2001 | Journal of Bone & Joint Surgery- British Volume2001，83，： | 1 |
| 17 | Detecting of circulating can- dida enlose by immuoassay in patients and in cancer in invasive candi- diasis显示文摘 | Walsh TJ Hathorn JW Sobel JD | 1991 | N Engl J Med1991，324，15： | 1 |
| 18 | Differentiation of radiation fibrosis from recurrent neoplasia:a role for 31P MR spectroscopy?显示文摘 | Cecil Charles H Baker ME Hathorn JW | 1990 | AJR1990，154，1： | 1 |
| 19 | A randomised trial comparing ceftazidime alone with combination antibiotic therapy in cancer patients with fever and neutropenia显示文摘 | Hathorn T W Hiomenz T | 1986 | N Engl T Med1986，315，： | 1 |
| 20 | A multicenter,randomized trial of fluconazole versus amphotericin B for empiric antifungal therapy of febrile neutropenic patients with cancer显示文摘 | Winston DJ Hathorn JW Schuster MG | 2000 | Am J Med2000，108，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员