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| 1 | A new strategy to prepare branching polyethylene by using an a-diimine nickel (II) complex covalently supported on MgCl2/AlRn(OEt)3-n显示文摘 | Hongliu Jiang Fuan He Haihua Wang | 2009 | Journal of Polymer Research2009，16，2： | 1 |
| 2 | The attachment of Fe3O4 nanopartieles to grapheme oxide by covalent bonding 显示文摘 | He Fuan Fan Jintu Ma Dong Zhang Liming Leung Chiwah Chan Helen Laiwa | 2010 | Carbon2010，48，11： | 1 |
| 3 | Auxin signaling module OsSK41-OsIAA10-OsARF regulates grain yield traits in rice显示文摘Auxin is an important phytohormone in plants, and auxin signaling pathways in rice play key roles in regulating its growth, development, and productivity. To investigate how rice grain yield traits are regulated by auxin signaling pathways and to facilitate their application in rice improvement, we validated the functional relationships among regulatory genes such as OsIAA10, OsSK41, and OsARF21 that are involved in one of the auxin(OsIAA10) signaling pathways. We assessed the phenotypic effects of these genes on several grain yield traits across two environments using knockout and/or overexpression transgenic lines.Based on the results, we constructed a model that showed how grain yield traits were regulated by OsIAA10 and OsTIR1, OsAFB2, and OsSK41 and OsmiR393 in the OsSK41-OsIAA10-OsARF module and by OsARF21 in the transcriptional regulation of downstream auxin response genes in the OsSK41-OsIAA10-OsARF module. The population genomic analyses revealed rich genetic diversity and the presence of major functional alleles at most of these loci in rice populations. The strong differentiation of many major alleles between Xian/indica and Geng/japonica subspecies and/or among modern varieties and landraces suggested that they contributed to improved productivity during evolution and breeding. We identified several important aspects associated with the genetic and molecular bases of rice grain and yield traits that were regulated by auxin signaling pathways.We also suggested rice auxin response factor(OsARF) activators as candidate target genes for improving specific target traits by overexpression and/or editing subspecies-specific alleles and by searching and pyramiding the ‘best' gene allelic combinations at multiple regulatory genes in auxin signaling pathways in rice breeding programs. | Fuying Ma Fan Zhang Yu Zhu Dengyong Lan Peiwen Yan Ying Wang Zejun Hu Xinwei Zhang Jian Hu Fuan Niu Mingyu Liu Shicong He Jinhao Cui Xinyu Yuan Ying Yan Shujun Wu Liming Cao Hongwu Bian Jinshui Yang Zhikang Li Xiaojin Luo | 2023 | Journal of Integrative Plant Biology2023，65，7： | 1 |
| 4 | The attachment of Fe 3 O 4 nanoparticles to graphene oxide by covalent bonding显示文摘 | Fuan He Jintu Fan Dong Ma Liming Zhang Chiwah Leung Helen Laiwa Chan | 2010 | Carbon2010，，11： | 1 |
| 5 | Fabrication of graphene nanosheet (GNS)–Fe 3 O 4 hybrids and GNS–Fe 3 O 4 /syndiotactic polystyrene composites with high dielectric permittivity显示文摘 | Fuan He Kwokho Lam Dong Ma Jintu Fan Laiwa Helen Chan Liming Zhang | 2013 | Carbon2013，，： | 1 |
| 6 | The attachment of Fe3O4 nanoparticles to graphene oxide by covalent bonding 显示文摘 | Fuan He Jintu Fan Dong Ma | 2010 | Carbon2010，48，： | 1 |
| 7 | Construction of a Stimuli-Responsive DNAzyme-Braked DNA Nanomachine for the Amplified Imaging of miRNAs in Living Cells and Mice显示文摘Synthetic DNA motors have spurred considerable research interest as a way to interrogate biochemical processes that can further facilitate disease diagnosis.However,current direct sense-on-demand DNA motors are hampered by undesired signal leakage originating from their nonspecific stimulation prior to their arrival at target sites.Herein,we propose a DNAzyme-guided DNA amplification motor through the facile built-in of a stimuli-responsive DNAzyme brake to facilitate the in vivo sensitive imaging of biomarkers by minimizing the off-site signal leakage in living systems.To realize the on-site activation,the inactive DNAzyme DNA motor was encapsulated into the folate(FA)-modified zeolitic imidazolate framework-8(ZIF-8)/poly(D,L-lactic-co-glycolic acid(PLGA)nanovesicles.The FA interaction-promoted tumor-cell-selective delivery and the pH-responsive disassembly of ZIF-8/PLGA permitted sufficient release of DNAzyme cofactors to achieve on-site stimulation of DNAzyme for restoring the temporally caged DNA amplification motor in tumor cells where the endogenous miRNA target was thus specifically and sensitively analyzed.By integration of the cellselective delivery and the site-specific stimulation,our DNAzyme-guided DNA motor can realize the reliable imaging of tumor cells and provide a new toolbox for disease diagnosis. | Yingying Chen Mingzhu Yan Yushi Wang Jinhua Shang Shizhen He Yuhui Gao Chen Hong Xiaoqing Liu Fuan Wang | 2023 | CCS Chemistry2023，5，7： | 0 |
| 8 | Construction of a Homogeneous Enzyme-Free Autocatalytic Nucleic Acid Machinery for High-Performance Intracellular Imaging of MicroRNA显示文摘Enzyme-free autocatalytic nucleic acidmachinery has been widely used to engineer various self-assembled nanostructures as well as high-performance bioanalysis,yet has rarely been realized in live cells for complicated design,low robustness,and limited reliability.Herein,we constructed simple yet versatile enthalpy-driven autocatalytic hybridization chain reaction(AHCR)machinery with high reliability and robustness for in situ microRNA analysis in live cells.The homogeneous AHCR machine was composed of two differently designed HCR modules,the lead-in HCR-1 amplification module,and the reverse HCR-2 feedback module.After the AHCR amplification system was delivered into live cells,target microRNA stimulated the autonomous cross-invasion of the HCR-1 module and the HCR-2 module for assembling hyperbranched dsDNA nanostructures with synergistically amplified Förster resonance energy transfer readout,thus enabling accurate intracellular micro-RNA imaging.The synergistic AHCR execution was systematically investigated by a series of experimental studies and computer-aided theoretical simulations.The multiple recognition capacity of HCR constituents and the successive signal amplification of the AHCR machine enabled the accurate intracellular microRNA imaging with precise signal localization inside living cells.Based on its intriguing and modular design,the AHCR machinery can be extended for analyzing diverse biomarkers,thus supplementing a powerful toolbox for clinical diagnosis and therapeutic assessment. | Jie Wei Jinhua Shang Shizhen He Yu Ouyang Itamar Willner Fuan Wang | 2022 | CCS Chemistry2022，4，11： | 0 |
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