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| 1 | Generalized Manifold-Ranking-Based Image Retrieval显示文摘 | He Jingrui Li Mingjing Zhang Hongjiang | 2006 | IEEE Trans Image Process2006，15，10： | 1 |
| 2 | Manifold-Ranking-Based Keyword Propagation for Image Retrieval显示文摘 | Tong Hanghang He Jingrui Li Mingjing | 2009 | EURASIP Journal on Applied Signal Processing2009，2006，： | 1 |
| 3 | Gen- eralized manifold ranking based image retrieval 显示文摘 | HE Jingrui LI Mingjing ZHANG Hongjiang | 2006 | IEEE Transactions on Image Process2006，15，10： | 1 |
| 4 | Mani- fold-ranking-based keyword propagation for image retrieval显示文摘 | TANG HANGHANG HE JINGRUI LI MINGJING | 2006 | Jour- nal on Applied Signal Processing2006，2006，1： | 1 |
| 5 | iNet:visual analysis of irregular transition in multivariate dynamic networks显示文摘Multivariate dynamic networks indicate networks whose topology structure and vertex attributes are evolving along time.They are common in multimedia applications.Anomaly detection is one of the essential tasks in analyzing these networks though it is not well addressed.In this paper,we combine a rare category detection method and visualization techniques to help users to identify and analyze anomalies in multivariate dynamic networks.We conclude features of rare categories and two types of anomalies of rare categories.Then we present a novel rare category detection method,called DIRAD,to detect rare category candidates with anomalies.We develop a prototype system called iNet,which integrates two major visualization components,including a glyph-based rare category identifier,which helps users to identify rare categories among detected substructures,a major view,which assists users to analyze and interpret the anomalies of rare categories in network topology and vertex attributes.Evaluations,including an algorithm performance evaluation,a case study,and a user study,are conducted to test the effectiveness of proposed methods. | Dongming HAN Jiacheng PAN Rusheng PAN Dawei ZHOU Nan CAO Jingrui HE Mingliang XU Wei CHEN | 2022 | Frontiers of Computer Science2022，16，2： | 0 |
| 6 | ACSL5,a prognostic factor in acute myeloid leukemia,modulates the activity of Wnt/β-catenin signaling by palmitoylation modification显示文摘Acyl-CoA synthetase long chain family member 5(ACSL5),is a member of the acyl-CoA synthetases(ACSs)family that activates long chain fatty acids by catalyzing the synthesis of fatty acyl-CoAs.The dysregulation of ACSL5 has been reported in some cancers,such as glioma and colon cancers.However,little is known about the role of ACSL5 in acute myeloid leukemia(AML).We found that the expression of ACSL5 was higher in bone marrow cells from AML patients compared with that from healthy donors.ACSL5 level could serve as an independent prognostic predictor of the overall survival of AML patients.In AML cells,the ACSL5 knockdown inhibited cell growth both in vitro and in vivo.Mechanistically,the knockdown of ACSL5 suppressed the activation of the Wnt/β-catenin pathway by suppressing the palmitoylation modification of Wnt3a.Additionally,triacsin c,a pan-ACS family inhibitor,inhibited cell growth and robustly induced cell apoptosis when combined with ABT-199,the FDA approved BCL-2 inhibitor for AML therapy.Our results indicate that ACSL5 is a potential prognosis marker for AML and a promising pharmacological target for the treatment of molecularly stratified AML. | Wenle Ye Jinghan Wang Jiansong Huang Xiao He Zhixin Ma Xia Li Xin Huang Fenglin Li Shujuan Huang Jiajia Pan Jingrui Jin Qing Ling Yungui Wang Yongping Yu Jie Sun Jie Jin | 2023 | Frontiers of Medicine2023，17，4： | 0 |
| 7 | Fluorine-containing drugs approved by the FDA in 2021显示文摘Nine new fluorine-containing drugs have been approved by the US Food and Drug Administration(FDA)in 2021,which are presented in this review article.These small molecular drugs feature aromatic fluorine,trifluoromethyl and chlorodifluoro groups.The therapeutic areas of these fluorine-containing drugs include multiple myeloma,lymphoma,HIV,chronic heart failure,chronic myeloid leukemia,(ANCA)-associated vasculitis,migraines,von Hippel-Lindau disease,and non-small cell lung cancer.The brief biological activities and the synthetic methods have been discussed in this review for each of these nine drugs. | Jingrui He Ziyi Li Gagan Dhawan Wei Zhang Alexander E.Sorochinsky Greg Butler Vadim A.Soloshonok Jianlin Han | 2023 | Chinese Chemical Letters2023，34，1： | 0 |
| 8 | Visible-light-irradiated tandem sulfonylation/cyclization of indole tethered alkenes for the synthesis of tetrahydrocarbazoles显示文摘A visible-light-mediated reaction of indole derivatives employing arylsulfonyl chlorides as sulfonyl surrogates has been developed,which proceeds via the sequence of reduction of sulfonyl chloride,sulfonylation,and intramolecular cyclization.This mild protocol transforms a diverse array of indole tethered alkenes and simple sulfonyl chlorides into highly valuable functionalized tetrahydrocarbazoles in good yields.This reaction is also suitable for gram-scale synthesis,which provides an efficient and green access to multi-substituted tetrahydrocarbazoles. | Yingjie Yu Aiyao Liu Jingrui He Chengting Wang Haibo Mei Jianlin Han | 2022 | Chinese Chemical Letters2022，33，11： | 0 |
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