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| 1 | Effect of dynamic light at the coronary care unit on the length of hospital stay and development of delirium: a retrospective cohort study显示文摘BackgroundDisturbed 生理节奏的节奏是谵妄的一个潜在的原因并且被连接到生理节奏的 rhythmicity 的 disorganisation。动态光(DL ) 能由 suprachiasmatic 原子核的激活重设生理节奏的节奏阻止谵妄。关于轻治疗的效果的证据主要集中于精神病学的混乱和生理节奏的节奏睡觉混乱。在这研究,我们在停留(LOS ) 的全部的医院长度上调查了 DL 的效果,在病人的谵妄的出现承认 .MethodsThis 是回顾的队研究到联合起来的冠的照顾(CCU ) 。比 18 年老的病人,在 CCU 比 12 h 长被就医并且为至少 24 h 有全部的医院 LOS,被包括。病人们与 DL 被分到一个房间(n = 369 ) 或常规点亮条件(n = 379 ) 。DL 被与在 2700 和 6500 度凯尔文之间的颜色温度交付光的二块装天花板的轻面板在 CCU 管理。报导结果数据是:全部的医院 LOS,谵妄发生,一个老人病学者的会诊和 prescripted antipsychotics.ResultsBetween 2015 年 5 月和 2016 年 5 月的数量,从 748 个病人的数据被收集。包括挑起谵妄的风险因素,基线特征在两个组是相等的。在 DL 组的中部的全部的医院 LOS 是 100.5 (70.8-186.0 ) 并且 101.0 (73.0-176.4 ) 在控制组的 h (P = 0.935 ) 。在 DL 和控制组的谵妄的发生是 5.4%(20/369 ) 并且 5.0%(19/379 ) ,分别地(P = 0.802 ) 。DL 和控制组之间的重要差别都没在第二等的端点被观察。亚群分析也基于年龄和 CCU LOS 证明当一条早单个的途径不导致全部的医院 LOS 的减小或减少谵妄的发生,没有 differences.ConclusionOur 学习建议暴露到 DL。当谵妄被诊断时,它与差的医院结果被联系。 | Tobias Pustjens Antonius MC Schoutens Loes Janssen Wilfred F Heesen | 2018 | Journal of Geriatric Cardiology2018，15，9： | 2 |
| 2 | The CD14-260 C→T promoter polymorphism co-segregates with the tumor necrosis factor-alpha (TNF-alpha)-308 G→A polymorphism and is associated with the interleukin-1 beta ( IL-1 beta) synthesis capacity of human leukocytes 显示文摘 | Heesen M Bloemeke B Bachmann-Mennenga B | 2002 | Eur Cytokine Netw2002，13，2： | 1 |
| 3 | Does the type of volume therapy influence endothelial-related coagulation in the critically ill? 显示文摘 | Boldt J Heesen M Welters I | 1995 | Br J Anaesth1995，75，6： | 1 |
| 4 | Vasopressors for the treat- ment of maternal hypotension following spinal anaesthesia for e- lective caesarean section: past, present and future显示文摘 | Heesen M Stewart A Fernando R | 2015 | Anaesthe- sia2015，70，3： | 1 |
| 5 | Coagulation alterations in patients undergoing elective craniotomy显示文摘 | Heesen M Kemkes-Matthes B Deinsberger W | 1997 | Surg Neurol1997，47，1： | 1 |
| 6 | New process control system of Hoogovens hot strip millkey to improved product quality显示文摘 | Heesen G J Burggraaf D H | 1991 | Ironmaking and Steelmaking1991，18，3： | 1 |
| 7 | Linkage disequlibrium between tumor necrosis factor( TNF)-alpha-308G/A promoter and TNF-beta Ncol polymorphisms: Association with TNF-alpha response of granulocytes to endotoxin stimulation 显示文摘 | Heesen M Kunz D Bachmann Mennenqa B | 2003 | Crit Care Med2003，31，： | 1 |
| 8 | Coagulation alterations in patients undergoing elective craniotomy显示文摘 | Heesen M Nemkes Matches B Deinsberger W | 1997 | Surg Neurol1997，47，1： | 1 |
| 9 | Cetennial review acuterespiratory distress syndrome a historical perspective显示文摘 | GORDON R BOLDT J HEESEN M | 2005 | Re-spir Crit Care Med2005，172，： | 1 |
| 10 | Maternal and foetal effects of remifentanil for general anaesthesia in parturients undergoing caesarean section : a systematic review and meta-analysis 显示文摘 | Heesen M Klfihr S Hofmann T | 2013 | Aeta Anaesthesiol Scand2013，57，1： | 1 |
| 11 | The effects of albumin versus hydroxyethyl starch solution on cardiorespiratory and circulatory variables in critically ill patients显示文摘 | Boldt J Heesen M Mller M | | 0，，02： | 1 |
| 12 | The effects of albumin versus hydroxyethl starch solution on cardiorespiratory and circulatory variables in critically ill patients显示文摘 | Boldt J Heesen M Muller M | 1996 | Anesth Analg1996，83，2： | 1 |
| 13 | Influence of different volume therapies on platelet function in the critically ill显示文摘 | Boldt J Mller M Heesen M | | 0，，10： | 1 |
| 14 | Coag- ulation alterations in patients undergoing elective eraniotomy 显示文摘 | Heesen M Kemkes-Matthes B Deinsberger W | 1997 | Surg Neurol1997，47，1： | 1 |
| 15 | Stress and hypothalamic-pituitary-adrenal axis function in experimental autoimmune encephalomyelitis and multiple sclerosis 显示文摘 | Heesen C Cold SM Huitinga t | 2007 | Psychoneuroendocrinology2007，32，6： | 1 |
| 16 | Pregabalin in patients with central neuropathic pain: A randomized, double-blind, placebo-controlled trial of a flexible-dose regimen显示文摘 | J.H. Vranken M.G.W. Dijkgraaf M.R. Kruis M.H. van der Vegt M.W. Hollmann M. Heesen | 2007 | Pain2007，，： | 1 |
| 17 | Effects of amlodip- ine and lisinopril on left ventricular mass and diastolic func- tion in previously untreated patients with mild to moderate diastolic hypertension显示文摘 | Beltman FW Heesen WF Smit A J | 1998 | Blood press1998，7，2： | 1 |
| 18 | Functional expression of the CXCchemokine receptor - 4/fusin on mouse micmglial cells and astrocytes 显示文摘 | Tanabe S Heesen M Yoshizawa I | 1997 | J Immunol1997，159，： | 1 |
| 19 | The effects of albumin versus hydroxyethyl starch solution on cardiorespiratory and circulatory variables in critically ill patients显示文摘 | Boldt J Heesen M Muller M | 1996 | Anesth Analg1996，83，： | 1 |
| 20 | Coagulation alterations in patients undergoingelective craniotomy 显示文摘 | Heesen M Ke mdes-Matthes B Deinsberger W | 1997 | Surg Neurol1997，47，1： | 1 |
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