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| 1 | Scoring of sperm chromosomal abnormalities by manual and automated approaches:qualitative and quantitative comparisons显示文摘精子 disomy 的层次相关到不孕的层次,现在是众所周知的(象另外的因素一样) 。永久维持 aneuploidy 到经历 intracytoplasmic 精子注射(ICSI ) 的不肥沃的男性的后代的风险在帮助复制成为了一个暑热地辩论的问题;然而,在那里仍然是障碍到为精子提供在一个临床的背景屏蔽的 disomy 的实际实现。主要障碍是花到分析的操作员时间一统计上有意义(足够) 房间的数字。“自动化点数”的介绍软件鈥揾a rdware 联合介绍一个潜在的解决方案给这个问题。在这初步的确认研究,我们分析了 10 个病人,手工地并且用一个商业地可得到的点阻止。结果显示出在两条途径之间的统计上重要的关联因为当为双精子得分时,精子 disomy,而是没有关联得分被发现。对后者的最可能的解释作为一个单个双房间是二个仔细联系的精子头的明显的 overscoring。这些结果,和将续起的类似的进一步的研究,通知费用鈥揵e nefit 的帮助分析那单个诊所需要执行以便决定是否采用从要求 ICSI 治疗的人为对精子的评价作为一个平淡的工具屏蔽的精子 aneuploidy。 | Helen G. Tempest Siu Yan Cheng David J. Gillott Alan H. Handyside Alan R. Thomhill Darren K. Griffin | 2010 | Asian Journal of Andrology2010，12，2： | 2 |
| 2 | The Circadian Gene Period2 Plays an Important Role in Tumor Suppression and DNA Damage Response In Vivo显示文摘 | Loning Fu Helene Pelicano Jinsong Liu Peng Huang Cheng Chi Lee | 2002 | Cell2002，，1： | 1 |
| 3 | Hedgehog signaling displays a biphasic expression pattern during intestinal injury and repair显示文摘 | Rui Liang Peter Morris Steven S.C. Cho Helen E. Abud Xianqing Jin Wei Cheng | 2012 | Journal of Pediatric Surgery2012，，12： | 1 |
| 4 | OCT4: A Novel Biomarker for Dysgerminoma of the Ovary显示文摘 | Liang Cheng Antoinette Thomas Lawrence M Roth Wenxin Zheng Helen Michael Fadi W. Abdul Karim | 2004 | The American Journal of Surgical Pathology2004，，10： | 1 |
| 5 | personality, peer relations, and self-confidence as predictors of happiness and loneliness显示文摘 | Helen Cheng Adrian Furnham | 2002 | Journal of Adolescence2002，25，： | 1 |
| 6 | Childhood cognitive ability, education, and personality traits predict attainment in adult occupational prestige over 17years显示文摘 | Helen Cheng Adrian Furnham | 2012 | Journal of Vocational Behavior2012，，2： | 1 |
| 7 | Personality, self-esteem, and demographic predictions of happiness and depression显示文摘 | Helen Cheng Adrian Furnham | 2002 | Personality and Individual Differences2002，，6： | 1 |
| 8 | Extraction and analysis of soil organic acids 显示文摘 | Wang T S C Cheng S Y Helen Tung | 1967 | Soil Science1967，103，5： | 1 |
| 9 | Living status and psychological well-being: Social comparison as a moderator in later life显示文摘 | Sheung-Tak Cheng Helene H. Fung Alfred C. M. Chan | 2008 | Aging & Mental Health2008，，5： | 1 |
| 10 | Respiratory syncytial virus that lacks open reading frame 2 of the M2 gene (M2- 2)has altered growth characteristics and is attenuated in rodents显示文摘 | Hong Jin Xing Cheng Helen ZY Zhou | 2000 | Journal of Virology2000，74，： | 1 |
| 11 | Elderly Subset Analysis of Randomized Phase III Study Comparing Pemetrexed Plus Carboplatin with Docetaxel Plus Carboplatin as First-Line Treatment for Patients with Locally Advanced or Metastatic Non-Small Cell Lung Cancer显示文摘 | José Rodrigues Pereira Rebecca Cheng Mauro Orlando Joo-Hang Kim Helen Barraclough | 2013 | Drugs in R&D2013，，： | 1 |
| 12 | Extraction and analysis of soil organic acids显示文摘 | Wang T S C Cheng S Y Helen T | 1967 | Soil Science1967，103，5： | 1 |
| 13 | Reversible ophthalmoplegia associated with ipsilateral persistent primitive trigeminal altery: A case report显示文摘 | Lin Ya-Ju Helen L Sho-Jen Cheng Po | 2002 | Acta Neurologica Taiwanica2002，11，6： | 1 |
| 14 | The Circadian Gene Period2 Plays an Important Role in Tumor Suppression and DNA Damage Response In Vivo显示文摘 | Loning Fu Helene Pelicano Jinsong Liu Peng Huang Cheng Chi Lee | 2002 | Cell2002，，1： | 1 |
| 15 | Androgen-regulated processing of the oncomir MiR-27a, which targets Prohibitin in prostate cancer显示文摘 | Claire E. Fletcher D. Alwyn Dart Ailsa Sita-Lumsden Helen Cheng Paul S. Rennie Charlotte L. Bevan | 2012 | Human Molecular Genetics2012，，14： | 1 |
| 16 | Reversible ophthalmoplegia associated with ipsilateral persistent primitive trigeminal artery : A case report 显示文摘 | Lin Ya-Ju Helen L Sho-Jen Cheng Po | 2002 | Acta Neurologica Taiwanica2002，11，6： | 1 |
| 17 | The potato P locus codes for flavonoid 3′,5′-hydroxylase显示文摘 | Chun Suk Jung Helen M. Griffiths Darlene M. De Jong Shuping Cheng Mary Bodis Walter S. De Jong | 2005 | Theoretical and Applied Genetics2005，，2： | 1 |
| 18 | Extraction and analysis of soil organic acids 显示文摘 | Wang T S C Cheng S Y Helen Tung | 1967 | Soil Science1967，103，5： | 1 |
| 19 | Attributional style and personality as predictors of happiness and mental health 显示文摘 | Helen cheng and Adrian furnham | 2001 | Journal of Happiness Studies2001，，2： | 1 |
| 20 | Estimation of genetic parameters and their sampling variances for quantitative traits in the type 2 modified augmented design显示文摘The type 2 modified augmented design(MAD2) is an efficient unreplicated experimental design used for evaluating large numbers of lines in plant breeding and for assessing genetic variation in a population. Statistical methods and data adjustment for soil heterogeneity have been previously described for this design. In the absence of replicated test genotypes in MAD2, their total variance cannot be partitioned into genetic and error components as required to estimate heritability and genetic correlation of quantitative traits, the two conventional genetic parameters used for breeding selection. We propose a method of estimating the error variance of unreplicated genotypes that uses replicated controls, and then of estimating the genetic parameters. Using the Delta method, we also derived formulas for estimating the sampling variances of the genetic parameters.Computer simulations indicated that the proposed method for estimating genetic parameters and their sampling variances was feasible and the reliability of the estimates was positively associated with the level of heritability of the trait. A case study of estimating the genetic parameters of three quantitative traits, iodine value, oil content, and linolenic acid content, in a biparental recombinant inbred line population of flax with 243 individuals, was conducted using our statistical models. A joint analysis of data over multiple years and sites was suggested for genetic parameter estimation. A pipeline module using SAS and Perl was developed to facilitate data analysis and appended to the previously developed MAD data analysis pipeline(http://gffzzebd7c0d4fd3c45a1hupxbwxwukc066fxf.ffgz.tsg.suse.edu.cn/bioinformatics_ tools/MADPipeline/index.html). | Frank M.You Qijian Song Gaofeng Jia Yanzhao Cheng Scott Duguid Helen Booker Sylvie Cloutier | 2016 | The Crop Journal2016，4，2： | 1 |
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