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| 1 | Watch and wait approach in rectal cancer:Current controversies and future directions显示文摘According to the main international clinical guidelines,the recommended treatment for locally-advanced rectal cancer is neoadjuvant chemoradiotherapy followed by surgery.However,doubts have been raised about the appropriate definition of clinical complete response(cCR)after neoadjuvant therapy and the role of surgery in patients who achieve a cCR.Surgical resection is associated with significant morbidity and decreased quality of life(QoL),which is especially relevant given the favourable prognosis in this patient subset. Accordingly, therehas been a growing interest in alternative approaches with less morbidity,including the organ-preserving watch and wait strategy, in which surgery isomitted in patients who have achieved a cCR. These patients are managed with aspecific follow-up protocol to ensure adequate cancer control, including the earlyidentification of recurrent disease. However, there are several open questionsabout this strategy, including patient selection, the clinical and radiologicalcriteria to accurately determine cCR, the duration of neoadjuvant treatment, therole of dose intensification (chemotherapy and/or radiotherapy), optimal followupprotocols, and the future perspectives of this approach. In the present review,we summarize the available evidence on the watch and wait strategy in thisclinical scenario, including ongoing clinical trials, QoL in these patients, and thecontroversies surrounding this treatment approach. | Fernando López-Campos Margarita Martín-Martín Roberto Fornell-Pérez Juan Carlos García-Pérez Javier Die-Trill Raquel Fuentes-Mateos Sergio López-Durán JoséDomínguez-Rullán Reyes Ferreiro AlejandroRiquelme-Oliveira Asunción Hervás-Morón Felipe Couñago | 2020 | World Journal of Gastroenterology2020，26，29： | 10 |
| 2 | Performance of PIVKA-II for early hepatocellular carcinoma diagnosis and prediction of microvascular invasion显示文摘 | Nicolas Poté Fran?ois Cauchy Miguel Albuquerque Hélène Voitot Jacques Belghiti Laurent Castera Hervé Puy Pierre Bedossa Valérie Paradis | 2014 | Journal of Hepatology2014，，： | 2 |
| 3 | Immunisation with a combination of two complementary feline calicivirus strains induces a broad cross-protection against heterologous challenges 显示文摘 | Herve P Sylvie B Vincent L | 2005 | Vet Microbiol2005，106，： | 1 |
| 4 | Long quadrilinear CCD sensors equipped with long linear filters-Characteristics and performances for the multispectral channel of earth observing systems显示文摘 | HERVE G JACQUES L ISABELLE L | | 0，，： | 1 |
| 5 | Electrovaporization of the prostate with the Gyrus device 显示文摘 | Botto H Lebret T Barr P Orsoni J L Herv J M Lugagne P M | 2001 | J Endourol2001，15，： | 1 |
| 6 | Monitoring landslides from optical remotely sensed imagery : the case history of Tessina land- slide, Italy 显示文摘 | Hervs J Barredo J I Rosin P L | 2003 | Geomorphology2003，54，1： | 1 |
| 7 | 16S rRNA and 16S to 23S internal transcribed spacer sequence analysisreveal inter and intraspecific Bifidobacteriumphylogeny显示文摘 | Nathalie L B Herve P Irene M | 1996 | lntem J Syst Bacteriology1996，46，： | 1 |
| 8 | L-Arginine and Pentoxfylline Attenuate Endothelial Dysfunction after Lung Reperfusion Injury in the Rabbit显示文摘 | NORMANDIN L HERVE P BRINK C | 1995 | Ann Thorac Surg(S0003-4975)1995，60，： | 1 |
| 9 | Mortality prognostic fac- tors in chest injury显示文摘 | Gaillard M Herve C Mandin L | 1990 | J Trauma1990，30，1： | 1 |
| 10 | 肺动脉高压启动治疗后血流动力学指标的预后价值显示文摘血流动力学指标,如心脏指数和右心房压力(right atrial pressure,RAP)与患者确诊肺动脉高压时的生存率持续相关。近期研究表明,肺动脉顺应性(pulmon aryarterial compliance,Pea)也可能预测肺动脉高压的预后。而在治疗开始之后测定的血流动力学指标对预后的价值还未确定。 | 黄洁 叶鹏 Weatherald J Boucly A Chemla D Savale L Peng M Jevnikar M Ja?s X Taniguchi Y O'Connell C Parent F Sattler C Hervé P Simonneau G Montani D Humbert M Adir Y Sitbon O | 2017 | 中华高血压杂志2017，25，11： | 1 |
| 11 | Infrared technique for simultaneous determination of temperature and emissivity 显示文摘 | Herve P Cedelle J Negreanu L | 2012 | lnfrared Physics &Technology2012，55，1： | 1 |
| 12 | Renal macrophage activation and TH2 polarization precedes the development of nephrotic syndrome in Buffalo/Mna rats显示文摘 | Le Berre L Herve C Buzelin F Usal C Soulillou JP Dantal J | 2005 | Kidney Int2005，68，5： | 1 |
| 13 | Evidence for loss of mitochondria in Microsporidia from amitochondrial-type HSP70 in Nosema locustae显示文摘 | Germot A Herve P Guyader H L | 1997 | Molecular and Biochemical Parasitology1997，87，： | 1 |
| 14 | The placenta: a main role in congenital toxoplasmosis?显示文摘 | Florence Robert-Gangneux Jean-Benjamin Murat Hélène Fricker-Hidalgo Marie-Pierre Brenier-Pinchart Jean-Pierre Gangneux Hervé Pelloux | 2011 | Trends in Parasitology2011，，12： | 1 |
| 15 | The use of a pretherapeutic,predictive score to determine inclusion xriteria for the non-surgical treatment of ectopix pregnancy显示文摘 | Herve F Christophe L Viviane T | 1991 | Hum Reprod1991，6，7： | 1 |
| 16 | Efficacy of a primary chemotherapy regimen combining vinorelbine,epirubicin,and methotrexate(VEM) as neoadjuvant treatmont in 89 patients with operable breast cancer显示文摘 | Isabelle VP Herv C Bernard L | 2002 | The Oncologist2002，7，5： | 1 |
| 17 | Monitoring landslides from optical remotely sensed imagery: the case history of Tessina landslide, Italy显示文摘 | Javier Hervás José I Barredo Paul L Rosin Alessandro Pasuto Franco Mantovani Sandro Silvano | 2003 | Geomorphology2003，，1： | 1 |
| 18 | Contamination performance of silicone rubber cable terminations part-2显示文摘 | Gorur R S Herving H C Johnson L A | 1991 | Transmission and Distribution Conference1991，22，： | 1 |
| 19 | 16S rRNA to 23S internal transcribed spacer sequence analyses reveal inter - and intraspecific Bifidobacterium phylogeny 显示文摘 | Nathalie L B Herve P Irene M | 1996 | International Journal of Systematic and Evolutionary Microbiology1996，46，1： | 1 |
| 20 | Sequence of the Kluyveromyces Lactis β-Galactosidase: comparision with prokaryotic enzymes and secondary structure analysis显示文摘 | OIJVIER P HERVE L HOTE L | 1992 | Gene1992，118，： | 1 |
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