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29篇 您的检索式:作者名="Highton"
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1Impact of postoperative intravenous fluid administration on complications following elective hepato-pancreato-biliary surgery显示文摘Background: The impact of perioperative intravenous fluid administration on surgical outcomes has been documented in literature, but not specifically studied in the context of hepato-pancreato-biliary(HPB) surgery. This study aimed to investigate the impact of postoperative intravenous fluid administration on intensive care unit(ICU), in this subgroup of patients. Methods: A single-center retrospective cohort of 241 HPB patients was assessed, focusing on intravenous fluid administration in ICU, during the first 24 h. Intravenous fluid variables were compared to hospital stay and postoperative complications. Data were assessed using Spearman's correlation test for bivariate correlations and logistic regression for multivariate analysis. Results: The median volume of intravenous fluid administered in the first 24 h postoperatively was 4380 mL, of which 2200 mL was crystalloid, 1500 mL colloid and 680 mL 'other' fluid. Patients with one or more complications had a higher median total intravenous fluid input(4790 vs. 4300 mL), higher colloid volume(20 0 0 vs. 150 0 mL), lower urine output(1595 vs. 1900 mL) and greater overall fluid balance( + 3040 vs. + 2553 mL) than those without complications. There were correlations between total intravenous fluid volume administered( r = 0.278, P < 0.001), intravenous colloid input( r = 0.278, P < 0.001), urine output( r =-0.295, P < 0.001), positive fluid balance( r = 0.344, P < 0.001) and length of hospital stay. Logistic regression model was constructed to predict the occurrence of one or more complications; total intravenous fluid volume and overall fluid balance were both independent significant predictors(OR = 2.463, P = 0.007; OR = 1.001, P = 0.011; respectively). Conclusions: Administration of high volumes of intravenous fluids in the first 24 hours post-HPB surgery, along with higher positive fluid balance is associated with a higher rate of complications and longer hospital stay. Moreover, lower urine output is associated with longer hospital stay. Whether these are the cause of complications or the result of them remains unclear.Daniel Martin Panagis M.Lykoudis Gabriel Jones David Highton Alan Shaw Sarah James Qiang Wei Giuseppe Fusai 2018Hepatobiliary & Pancreatic Diseases International2018,17,5:2
2Rationale for a trial of immunosuppressive therapy in acute schizophrenia 显示文摘KNIGHT JG MENKES DB HIGHTON J 2007Molecular Psychiatry2007,34,12:1
3Neuromuscular, biochemical and perceptual post - match fatigue in professional rugby league forwards and backs 显示文摘Twist C Waldron M Highton J Burt D and Daniels M 2012J Sports Sci2012,30,:1
4Retentive and stress characteristics for a magnetically-retained partial overdenture 显示文摘Highton R Caputo AA Matyas J 1986J Oral Rehabil1986,13,5:1
5A photoelastic study 6 of stresses ton porcelain laminate preparations显示文摘Highton R Caputo AA Mitys J 1987J Pros- thet Dent1987,58,2:1
6Rationale for a trial of immunosu -ppressive therapy in acute schizophrenia显示文摘KNIGHT J G MENKES D B HIGHTON J 2007Molecular Psychiatry2007,34,12:1
7Mathematical modelling of near-infrared spectroscopy signals and intracranial pressure in brain-injured pa- tients显示文摘Highton D Panovska-Griffiths J Smith M Elwell C E 2013Adv Exp Med Biol2013,789,:1
8A photoelastic study of stresses on porcelain laminate preparations显示文摘Highton R Caputo AA Matyas J 1987Prosther Dent1987,58,:1
9cytokine profile of the rheumatoid nodule suggests that id a Th1 granuloma显示文摘Hessian PA Highton J Kean A 2003Arthritis Rheum2003,48,2:1
10Mathematical modelling of near-infrared spectroscopy signals and intracranial pressure in brain-injured patients 显示文摘Highton D Panovska-Griffiths J Smith M 2013Adv Exp Med Biol2013,789,:1
11Cytokine profile of the rheumatoid nodule suggests that it is a Th1 granuloma显示文摘Hessian P A Highton J Kean A 2003Arthritis Rheum2003,48,2:1
12Cytokine profile of the rheumatoid nodule suggests that is a Th1 granuloma显示文摘HESSIAN PA HIGHTON J KEAN A 2003Arthritis Rheum2003,48,2:1
13Retentive and siress characteristics for a magnetically retained partialoverdenture显示文摘Highton R Caputo A A Matyas J 1986J Oral Rehabil1986,13,5:1
14Rationale for a trial of immunosuppressive therapy in acute schizophrenia显示文摘Knight JG Menkes DB Highton J 2007Molecular Psychiatry2007,12,5:1
15Rationale for a trial of immunosuppressive therapy in acute schizophrenia显示文摘Knight JG Menkes DB Highton J 2007Molecular Paychiatry2007,12,5:1
16Cell death by apoptosisis a feature of the rheumatoid nodule显示文摘Highton J Hessian PA Kean A 2003Ann Rheum Dis2003,62,1:1
17Retentive characteristics of different magnetic systems for dental applications显示文摘Highton R Caputo AA Pezzoli M 1986J Prosthet Dent1986,6,1:1
18Renal impairment and gout显示文摘Gibson T Highton J Potter C 1980Ann Rheum Dis1980,39,5:1
19Pneumonitis associated with leflunomide : A profile of New Zealand and Australian reports 显示文摘Savage RL Highton J Boyd IW 2006In- tern Med J2006,36,:1
20cytokine profile of the rheumatoid nodule suggests that id a Thl 显示文摘Hessian PA Highton J Kean A 2003granuloma Arthritis Rheum2003,48,2:1
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