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| 1 | Impact of postoperative intravenous fluid administration on complications following elective hepato-pancreato-biliary surgery显示文摘Background: The impact of perioperative intravenous fluid administration on surgical outcomes has been documented in literature, but not specifically studied in the context of hepato-pancreato-biliary(HPB) surgery. This study aimed to investigate the impact of postoperative intravenous fluid administration on intensive care unit(ICU), in this subgroup of patients. Methods: A single-center retrospective cohort of 241 HPB patients was assessed, focusing on intravenous fluid administration in ICU, during the first 24 h. Intravenous fluid variables were compared to hospital stay and postoperative complications. Data were assessed using Spearman's correlation test for bivariate correlations and logistic regression for multivariate analysis. Results: The median volume of intravenous fluid administered in the first 24 h postoperatively was 4380 mL, of which 2200 mL was crystalloid, 1500 mL colloid and 680 mL 'other' fluid. Patients with one or more complications had a higher median total intravenous fluid input(4790 vs. 4300 mL), higher colloid volume(20 0 0 vs. 150 0 mL), lower urine output(1595 vs. 1900 mL) and greater overall fluid balance( + 3040 vs. + 2553 mL) than those without complications. There were correlations between total intravenous fluid volume administered( r = 0.278, P < 0.001), intravenous colloid input( r = 0.278, P < 0.001), urine output( r =-0.295, P < 0.001), positive fluid balance( r = 0.344, P < 0.001) and length of hospital stay. Logistic regression model was constructed to predict the occurrence of one or more complications; total intravenous fluid volume and overall fluid balance were both independent significant predictors(OR = 2.463, P = 0.007; OR = 1.001, P = 0.011; respectively). Conclusions: Administration of high volumes of intravenous fluids in the first 24 hours post-HPB surgery, along with higher positive fluid balance is associated with a higher rate of complications and longer hospital stay. Moreover, lower urine output is associated with longer hospital stay. Whether these are the cause of complications or the result of them remains unclear. | Daniel Martin Panagis M.Lykoudis Gabriel Jones David Highton Alan Shaw Sarah James Qiang Wei Giuseppe Fusai | 2018 | Hepatobiliary & Pancreatic Diseases International2018，17，5： | 2 |
| 2 | Rapid detection and simultaneous subtype differentiation of influenza A viruses by real time PCR显示文摘 | Belinda Stone Julie Burrows Sonia Schepetiuk Geoff Higgins Alan Hampson Robert Shaw TuckWeng Kok | 2004 | Journal of Virological Methods2004，，2： | 1 |
| 3 | Acute Budd-Chiari syndrome during pregnancy: Surgical treatment and orthotopic liver transplantation with successful completion of the pregnancy显示文摘 | Wendy J. Grant Timothy McCashland Jean F. Botha Byers W. Shaw Debra L. Sudan Alejandro Mejia Kishore Iyer Alan N. Langnas | 2003 | Liver Transplantation2003，，9： | 1 |
| 4 | Weight change modulates epicardial fat burden: A 4-year serial study with non-contrast computed tomography显示文摘 | Ryo Nakazato Ronak Rajani Victor Y. Cheng Haim Shmilovich Rine Nakanishi Yuka Otaki Heidi Gransar Piotr J. Slomka Sean W. Hayes Louise E.J. Thomson John D. Friedman Nathan D. Wong Leslee J. Shaw Matthew Budoff Alan Rozanski Daniel S. Berman Damini Dey | 2011 | Atherosclerosis2011，，1： | 1 |
| 5 | Threshold for the Upper Normal Limit of Indexed Epicardial Fat Volume: Derivation in a Healthy Population and Validation in an Outcome-Based Study显示文摘 | Haim Shmilovich Damini Dey Victor Y. Cheng Ronak Rajani Ryo Nakazato Yuka Otaki Rine Nakanishi Piotr J. Slomka Louise E.J. Thomson Sean W. Hayes John D. Friedman Heidi Gransar Nathan D. Wong Leslee J. Shaw Matthew Budoff Alan Rozanski Daniel S. Berman | 2011 | The American Journal of Cardiology2011，，11： | 1 |
| 6 | Regulation of Phytochrome B Nuclear Localization through Light-Dependent Unmasking of Nuclear-Localization Signals显示文摘 | Meng Chen Yi Tao Jason Lim Alan Shaw Joanne Chory | 2005 | Current Biology2005，，7： | 1 |
| 7 | Mode of Death and Hospitalization from the Second Follow-Up Serial Infusions of Nesiritide (FUSION II) Trial and Comparison of Clinical Events Committee Adjudicated Versus Investigator Reported Outcomes显示文摘 | Christopher M. O’Connor Mona Fiuzat JoAnn Lindenfeld Alan Miller Carlo Lombardi Peter Carson Linda K. Shaw Li-Joy Wang Patricia Connolly Roger Mills Clyde Yancy Kenneth Mahaffey | 2011 | The American Journal of Cardiology2011，，10： | 1 |
| 8 | Extensive thoracic aortic calcification is an independent predictor of Development of coronary artery calcium among individuals with coronary artery calcium score of Zero显示文摘 | Yafim Brodov Heidi Gransar Alan Rozanski Sean W. Hayes John D. Friedman Louise E.J. Thomson Damini Dey James K. Min Leslee J. Shaw P.K. Shah Guido Germano Daniel S. Berman | 2014 | Atherosclerosis2014，，： | 1 |
| 9 | The toxicity of textile reactive azo dyes after hydrolysis and decoiourisation显示文摘 | Anna Gottlieb Chris Shaw Alan Smith | 2003 | Journal of Biotechnology2003，101，： | 1 |
| 10 | The comparative efficacy of imputation methods for missing data in structural equation modeling 显示文摘 | Alan Olinsky Shaw Chen Lisa Harlow | 2003 | European Journal of Operational Research2003，151，： | 1 |
| 11 | Shunt Surgery During the Era of Liver Transplantation显示文摘 | Layton F. Rikkers Gongliang Jin Alan N. Langnas Byers W. Shaw | 1997 | Annals of Surgery1997，，1： | 1 |
| 12 | Comparative Value of Coronary Artery Calcium and Multiple Blood Biomarkers for Prognostication of Cardiovascular Events显示文摘 | Jamal S. Rana Heidi Gransar Nathan D. Wong Leslee Shaw Michael Pencina Khurram Nasir Alan Rozanski Sean W. Hayes Louise E. Thomson John D. Friedman James K. Min Daniel S. Berman | 2012 | The American Journal of Cardiology2012，，10： | 1 |
| 13 | What factors influence patient experience in orthopedic oncology office visits?显示文摘BACKGROUND Patient satisfaction and reported outcomes are becoming increasingly important in determining the efficacy of clinical care.To date no study has evaluated the patient experience in the orthopedic oncology outpatient setting to determine which factors of the encounter are priorities to the patient.AIM To evaluate what factors impact patient experience and report satisfaction in an outpatient orthopedic oncology clinic.METHODS Press Ganey®patient surveys from a single outpatient orthopedic oncology clinic at a tertiary care setting were prospectively collected per routine medical care.All orthopedic oncology patients who were seen in clinic and received electronic survey were included.All survey responses were submitted within one month of clinic appointment.IRB approval was obtained to retrospectively collect survey responses from 2015 to 2016.Basic demographic data along with survey category responses were collected and statistically analyzed.RESULTS One hundred sixty-two patient surveys were collected.Average patient age was 54.4 years(SD=16.2 years)and were comprised of 51.2% female and 48.4%male.64.2%of patients were from in-state.Out of state residents were more likely to recommend both the practice and attending physician.The likelihood to recommend attending physician was positively associated with MD friendliness/courtesy(OR=14.4,95%CI:2.5-84.3),MD confidence(OR=48.2,95%CI:6.2-376.5),MD instructions follow-up care(OR=2.5,95%CI:0.4-17.4),and sensitivity to needs(OR=16.1,95%CI:1-262.5).Clinic operations performed well in the categories of courtesy of staff(76%)and cleanliness(75%)and less well in ease of getting on the phone(49%),information about delays(36%),and wait time(37%).CONCLUSION Orthopedic specialties can utilize information from this study to improve care from the patient perspective.Future studies may be directed at how to improve these areas of care which are most valued by the patient. | Alan T Blank Sara Shaw Connor J Wakefield Yue Zhang Wei J Liu Kevin B Jones R Lor Randall | 2020 | World Journal of Clinical Oncology2020，11，3： | 0 |
| 14 | National Comprehensive Cancer Network guidelines compliance of a sarcoma service:A retrospective review显示文摘BACKGROUND Clinical workup and treatment guidelines have been published by the National Comprehensive Cancer Network(NCCN)to ensure patients are treated uniformly and appropriately.This study sought to retrospectively review patients with a new diagnosis of sarcoma who were treated in a National Cancer Institute(NCI)designated center and determine compliance rates with guidelines for sarcoma.AIM To evaluate our compliance of NCCN sarcoma guidelines at a major NCI designated center and to report instances of deviation that could be used for future studies to improve patient care.METHODS Data was collected retrospectively as an internal review and quality assessment of 35 newly diagnosed and treated patients.Demographic data were recorded and information concerning whether patients had appropriate imaging,biopsy and management.Variables of interest were expressed as raw numbers and percentages.RESULTS Primary site imaging was obtained in 100%of cases.Chest and full-body imaging were obtained in 97%and 100%of indicated cases,respectively.Tissue was obtained preoperatively in 97%of cases.Imaging was reviewed at multidisciplinary Treatment Planning Conference(TPC)in 97%of cases.Pathology was reviewed in 94%of cases in TPC.Both tumor,node,metastasis staging and plan of care were reviewed in 100%of cases in TPC.Treatment guidelines were followed in 94%of cases reviewed.CONCLUSION This study evaluated the workup and treatment provided by a single NCI designated sarcoma service to a series of patients with pathologies defined with the NCCN sarcoma treatment guidelines.Although adherence to NCCN was reported to be very high future prospective studies are required to investigate whether NCCN guidelines impact patient outcomes. | Alan T Blank Brandon Michael Larson Sara Shaw Connor J Wakefield Tricia King Kevin B Jones R Lor Randall | 2020 | World Journal of Clinical Oncology2020，11，6： | 0 |
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