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| 1 | Prophylactic lateral pelvic lymph node dissection in stage Ⅳ low rectal cancer显示文摘AIM To assess the clinical significance of prophylactic lateral pelvic lymph node dissection (LPLND) in stage Ⅳ low rectal cancer.METHODS We selected 71 consecutive stage Ⅳ low rectal cancer patients who underwent primary tumor resection,and enrolled 50 of these 71 patients without clinical LPLN metastasis.The patients had distant metastasis such as liver,lung,peritoneum,and paraaortic LN.Clinical LPLN metastasis was defined as LN with a maximum diameter of 10 mm or more on preoperative pelvic computed tomography scan.All patients underwent primary tumor resection,27 patients underwent total mesorectal excision(TME) with LPLND(LPLND group),and 23 patients underwent only TME(TME group).Bilateral LPLND was performed simultaneously with primary tumor resection in LPLND group.R0 resection of both primary and metastatic sites was achieved in 20 of 50 patients.We evaluated possible prognostic factors for 5-year overall survival (OS),and compared 5-year cumulative local recurrence between the LPLND and TME groups.RESULTS For OS,univariate analyses revealed no significant benefit in the LPLND compared with the TME group (28.7% vs 17.0%,P = 0.523); multivariate analysis revealed that R0 resection was an independent prognostic factor.Regarding cumulative local recurrence,the LPLND group showed no significant benefit compared with TME group (21.4% vs 14.8%,P = 0.833).CONCLUSION Prophylactic LPLND shows no oncological benefits in patients with Stage Ⅳ low rectal cancer without clinical LPLN metastasis. | Hiroshi Tamura Yoshifumi Shimada Hitoshi Kameyama Ryoma Yagi Yosuke Tajima Takuma Okamura Mae Nakano Masato Nakano Masayuki Nagahashi Jun Sakata Takashi Kobayashi Shin-ichi Kosugi Hitoshi Nogami Satoshi Maruyama Yasumasa Takii Toshifumi Wakai | 2017 | World Journal of Clinical Oncology2017，8，5： | 4 |
| 2 | Microscopic structure and thermoresponsiveness of a hydrogel nanoparticle by self-assembly of a hydrophobized polysaccharide 显示文摘 | Kazunari Akiyoshi Shigeru Deguchi Hitoshi Tajima | 1997 | Macromolecules1997，30，： | 1 |
| 3 | Coil embolization of arterioportal fistula that developed after partial gastrectomy显示文摘 | Kousei Ishigami Kengo Yoshimitsu Hiroshi Honda Toshiro Kuroiwa Hiroyuki Irie Hitoshi Aibe Tsuyoshi Tajima Makoto Hashizume Kouji Masuda | 1999 | CardioVascular and Interventional Radiology1999，，4： | 1 |
| 4 | Well-differentiated adenocarcinoma of the gallbladder with intratumoral cystic components due to abundant mucin production: a mimicker of adenomyomatosis显示文摘 | Kengo Yoshimitsu Hiroyuki Irie Hitoshi Aibe Tsuyoshi Tajima Akihiro Nishie Yoshiki Asayama Kunishige Matake Kouji Yamaguchi Shuji Matsuura Hiroshi Honda | 2005 | European Radiology2005，，2： | 1 |
| 5 | Study on onstruetion loads during shield ttmneling using a three- dimensional FEM model 显示文摘 | Hitoshi Tajima Masaito Kishida Naomitsu Fukai | 2006 | Tunnelling and Undergound Space Technology2006，21，： | 1 |
| 6 | Well-differentiated adenocarcinoma of the gallbladder with intratumoral cystic components due to abundant mucin production: a mimicker of adenomyomatosis显示文摘 | Kengo Yoshimitsu Hiroyuki Irie Hitoshi Aibe Tsuyoshi Tajima Akihiro Nishie Yoshiki Asayama Kunishige Matake Kouji Yamaguchi Shuji Matsuura Hiroshi Honda | 2005 | European Radiology2005，，： | 1 |
| 7 | Pulmonary Complications after Hepatic Artery Chemoembolization or Infusion via the Inferior Phrenic Artery for Primary Liver Cancer显示文摘 | Tsuyoshi Tajima Hiroshi Honda Toshirou Kuroiwa Hidetake Yabuuchi Takashi Okafuji Kengo Yosimitsu Hiroyuki Irie Hitoshi Aibe Kouji Masuda | 2002 | Journal of Vascular and Interventional Radiology2002，，9： | 1 |
| 8 | Study on construction loads during shield tunneling using a three dimensional FEM model显示文摘 | Masahiko Kishida Naomitsu Fukai Akihiro Dan Masayuki Saito | 2006 | Tunnelling and Underground Space Technology2006，250，： | 1 |
| 9 | Immunohistochemical studies on oncogene products (c-erbB-2, EGFR, c-myc) and estrogen receptor in benign and malignant breast lesions显示文摘 | Katsunori Tauchi Sadaaki Hori Hitoshi Itoh R. Yoshiyuki Osamura Yutaka Tokuda Tomoo Tajima | 1989 | Virchows Archiv A Pathological Anatomy and Histopathology1989，，1： | 1 |
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