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| 1 | Risk assessment of malaria transmission at the border area of China and Myanmar显示文摘Background:In order to achieve the goal of malaria elimination,the Chinese government launched the National Malaria Elimination Programme in 2010.However,as a result of increasing cross-border population movements,the risk of imported malaria cases still exists at the border areas of China,resulting in a potential threat of local transmission.The focus of this paper is to assess the Plasmodium vivax incidences in Tengchong,Yunnan Province,at the border areas of China and Myanmar.Methods:Time series of P.vivax incidences in Tengchong from 2006 to 2010 are collected from the web-based China Information System for Disease Control and Prevention,which are further separated into time series of imported and local cases.First,the seasonal and trend decomposition are performed on time series of imported cases using Loess method.Then,the impact of climatic factors on the local transmission of P.vivax is assessed using both linear regression models(LRM)and generalized additive models(GAM).Specifically,the notion of vectorial capacity(VCAP)is used to estimate the transmission potential of P.vivax at different locations,which is calculated based on temperature and rainfall collected from China Meteorological Administration.Results:Comparing with Ruili County,the seasonal pattern of imported cases in Tengchong is different:Tengchong has only one peak,while Ruili has two peaks during each year.This may be due to the different cross-border behaviors of peoples in two locations.The vectorial capacity together with the imported cases and the average humidity,can well explain the local incidences of P.vivax through both LRM and GAM methods.Moreover,the maximum daily temperature is verified to be more suitable to calculate VCAP than the minimal and average temperature in Tengchong County.Conclusion:To achieve malaria elimination in China,the assessment results in this paper will provide further guidance in active surveillance and control of malaria at the border areas of China and Myanmar. | Benyun Shi Jinxin Zheng Hongjun Qiu Guo-Jing Yang Shang Xia Xiao-Nong Zhou | 2017 | Infectious Diseases of Poverty2017，6，1： | 6 |
| 2 | Pathological features of COVID-19-associated lung injury:a preliminary proteomics report based on clinical samples显示文摘The COVID-19 pandemic has emerged as a global health emergency due to its association with severe pneumonia and relative high mortality.However,the molecular characteristics and pathological features underlying COVID-19 pneumonia remain largely unknown.To characterize molecular mechanisms underlying COVID-19 pathogenesis in the lung tissue using a proteomic approach,fresh lung tissues were obtained from newly deceased patients with COVID-19 pneumonia.After virus inactivation,a quantitative proteomic approach combined with bioinformatics analysis was used to detect proteomic changes in the SARS-CoV-2-infected lung tissues.We identified significant differentially expressed proteins involved in a variety of fundamental biological processes including cellular metabolism,blood coagulation,immune response,angiogenesis,and cell microenvironment regulation.Several inflammatory factors were upregulated,which was possibly caused by the activation of NF-κB signaling.Extensive dysregulation of the lung proteome in response to SARS-CoV-2 infection was discovered.Our results systematically outlined the molecular pathological features in terms of the lung response to SARS-CoV-2 infection,and provided the scientific basis for the therapeutic target that is urgently needed to control the COVID-19 pandemic. | Ling Leng Ruiyuan Cao Jie Ma Danlei Mou Yunping Zhu Wei Li Luye Lv Dunqin Gao Shikun Zhang Feng Gong Lei Zhao Bintao Qiu Haiping Xiang Zhongjie Hu Yingmei Feng Yan Dai Jiang Zhao Zhihong Wu Hongjun Li Wu Zhong | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 4 |
| 3 | Mapping of wheat stripe rust resistance gene Yr041133 by BSR-Seq analysis显示文摘Puccinia striiformis Westend. f. sp. tritici(Pst) pathotype CYR34 is widely virulent and prevalent in China.Here, we report identification of a strpie rust resistance(Yr) gene, designated Yr041133, in winter wheat line 041133. This line produced a hypersensitive reaction to CYR34 and conferred resistance to 13 other pathotypes. Resistance to CYR34 in line 041133 was controlled by a single dominant gene. Bulked segregant RNA sequencing(BSR-Seq) was performed on a pair of RNA bulks generated by pooling resistant and susceptible recombinant inbred lines. Yr041133 was mapped to a 1.7 c M genetic interval on the chromosome arm 7 BL that corresponded to a 0.8 Mb physical interval(608.9–609.7 Mb) in the Chinese Spring reference genome. Based on its unique physical location Yr041133 differred from the other Yr genes on this chromosome arm. | Yahui Li Ruiming Lin Jinghuang Hu Xiaohan Shi Dan Qiu Peipei Wu Gebremedhin Habteab Goitom Siqi Wang Hongjun Zhang Li Yang Hongwei Liu Qiuhong Wu Jingzhong Xie Yang Zhou Zhiyong Liu Hongjie Li | 2022 | The Crop Journal2022，10，2： | 1 |
| 4 | The Mycoplasma gallisepticum α-enolase is cell surface-exposed and mediates adherence by binding to chicken plasminogen显示文摘 | Hongjun Chen Shengqing Yu Xinyue Shen Danqing Chen Xvsheng Qiu Cuiping Song Chan Ding | 2011 | Microbial Pathogenesis2011，，： | 1 |
| 5 | Local existence of strong solution for a class of compressible non-Newtonian fluids with non-Newtonian potential显示文摘 | Yuan Hongjun Meng qiu | 2013 | Computers &Mathematics with Applications2013，65，4： | 1 |
| 6 | Whole genome sequencing and biological characterization of Duck/JS/10, a new lentogenic class I Newcastle disease virus显示文摘 | Chunchun Meng Xvsheng Qiu Shiqiang Jin Shengqing Yu Hongjun Chen Chan Ding | 2012 | Archives of Virology2012，，5： | 1 |
| 7 | Whole genome sequencing and biological characterization of Duck/JS/10, a new lentogenic class I Newcastle disease virus显示文摘 | Chunchun Meng Xvsheng Qiu Shiqiang Jin Shengqing Yu Hongjun Chen Chan Ding | 2012 | Archives of Virology2012，，5： | 1 |
| 8 | Identifying key bird species and geographical hotspots of avian influenza A(H7N9)virus in China显示文摘Background:In China since the first human infection of avian influenza A(H7N9)virus was identified in 2013,it has caused serious public health concerns due to its wide spread and high mortality rate.Evidence shows that bird migration plays an essential role in global spread of avian influenza viruses.Accordingly,in this paper,we aim to identify key bird species and geographical hotspots that are relevant to the transmission of avian influenza A(H7N9)virus in China.Methods:We first conducted phylogenetic analysis on 626 viral sequences of avian influenza A(H7N9)virus isolated in chicken,which were collected from the Global Initiative on Sharing All Influenza Data(GISAID),to reveal geographical spread and molecular evolution of the virus in China.Then,we adopted the cross correlation function(CCF)to explore the relationship between the identified influenza A(H7N9)cases and the spatiotemporal distribution of migratory birds.Here,the spatiotemporal distribution of bird species was generated based on bird observation data collected from China Bird Reports,which consists of 157272 observation records about 1145 bird species.Finally,we employed a kernel density estimator to identify geographical hotspots of bird habitat/stopover that are relevant to the influenza A(H7N9)infections.Results:Phylogenetic analysis reveals the evolutionary and geographical patterns of influenza A(H7N9)infections,where cases in the same or nearby municipality/provinces are clustered together with small evolutionary differences.Moreover,three epidemic waves in chicken along the East Asian-Australasian flyway in China are distinguished from the phylogenetic tree.The CCF analysis identifies possible migratory bird species that are relevant to the influenza A(H7N9)infections in Shanghai,Jiangsu,Zhejiang,Fujian,Jiangxi,and Guangdong in China,where the six municipality/provinces account for 91.2%of the total number of isolated H7N9 cases in chicken in GISAID.Based on the spatial distribution of identified bird species,geographical hotspots are further estimated and illustrated within these typical municipality/provinces.Conclusions:In this paper,we have identified key bird species and geographical hotspots that are relevant to the spread of influenza A(H7N9)virus.The results and findings could provide sentinel signal and evidence for active surveillance,as well as strategic control of influenza A(H7N9)transmission in China. | Benyun Shi Xiao-Ming Zhan Jin-Xin Zheng Hongjun Qiu Dan Liang Yan-Ming Ye Guo-Jing Yang Yang Liu Jiming Liu | 2018 | Infectious Diseases of Poverty2018，7，1： | 1 |
| 9 | On Bounded Positive(m,p)-Circle Domains显示文摘Let D be a bounded positive(m, p)-circle domain in C^2. The authors prove that if dim(Iso(D)~0) = 2, then D is holomorphically equivalent to a Reinhardt domain; if dim(Iso(D)~0) = 4, then D is holomorphically equivalent to the unit ball in C^2. Moreover,the authors prove the Thullen's classification on bounded Reinhardt domains in C^2 by the Lie group technique. | Hongjun LI Chunhui QIU Yichao XU | 2018 | Chinese Annals of Mathematics,Series B2018，39，4： | 0 |
| 10 | Strong Solutions for Nonhomogeneous Incompressible Viscous Heat-Conductive Fluids with Non-Newtonian Potential显示文摘 | MENG Qiu YUAN Hongjun | 2014 | Journal of Partial Differential Equations2014，27，3： | 0 |
| 11 | The Strong Solution for the Viscous Polytropic Fluids with Non-Newtonian Potential显示文摘The authors study an initial boundary value problem for the three-dimensional Navier-Stokes equations of viscous heat-conductive fluids with non-Newtonian potential in a bounded smooth domain. They prove the existence of unique local strong solutions for all initial data satisfying some compatibility conditions. The difficult of this type model is mainly that the equations are coupled with elliptic, parabolic and hyperbolic, and the vacuum of density causes also much trouble, that is, the initial density need not be positive and may vanish in an open set. | Qiu MENG Hongjun YUAN | 2019 | Chinese Annals of Mathematics,Series B2019，40，2： | 0 |
| 12 | On Regularity of Incompressible Fluid with Shear Dependent Viscosity显示文摘The authors consider a non-Newtonian fluid governed by equations with p-structure in a cubic domain.A fluid is said to be shear thinning(or pseudo-plastic) if 1 < p < 2,and shear thickening(or dilatant) if p > 2.The case p > 2 is considered in this paper.To improve the regularity results obtained by Crispo,it is shown that the secondorder derivatives of the velocity and the first-order derivative of the pressure belong to suitable spaces,by appealing to anisotropic Sobolev embeddings. | Hongjun YUAN Qiu MENG | 2012 | Chinese Annals of Mathematics,Series B2012，33，5： | 0 |
| 13 | Broadband 1T-polytype tantalum disulfide saturable absorber for solid-state bulk lasers显示文摘1T-polytype tantalum disulfide(1T-TaS_(2)),an emerging strongly correlated material,features a narrow bandgap of 0.2 e V,bridging the gap between zero-bandgap graphene and large-bandgap 2D nonlinear optical(NLO)materials.Combined with its intense light absorption,high carrier concentration,and high mobility,1T-TaS_(2) shows considerable potential for applications in broadband optoelectronic devices.However,its NLO characteristics and related applications have rarely been explored.Here,1T-TaS_(2) nanosheets are prepared by chemical vapor deposition.The ultrafast carrier dynamics in the 400–1100 nm range and broadband NLO performance in the 515–2500 nm range are systematically studied using femtosecond lasers.An obvious saturable absorption phenomenon is observed in the visible to IR range.The nonlinear absorption coefficient is measured to be-22.60±0.52 cm MW-1under 1030 nm,which is larger than that of other typical 2D saturable absorber(SA)materials(graphene,black phosphorus,and MoS_(2))under similar experimental conditions.Based on these findings,using 1T-TaS_(2) as a new SA,passively Q-switched laser operations are successfully performed at 1.06,1.34,and 1.94μm.The results highlight the promise of 1T-TaS_(2) for broadband optical modulators and provide a potential candidate material system for mid-IR nonlinear optical applications. | MENGXIA WANG HAILONG QIU TIANWEN YANG ZHENGPING WANG CHUANRUI ZHAO YUANAN ZHAO TING YU YUYAO JIANG MEILING CHEN YAFEI LIAN GE ZHANG HONGJUN LIU ZHANGGUI HU JIANDA SHAO | 2022 | Photonics Research2022，10，9： | 0 |
| 14 | On conformal complex Finsler metrics显示文摘In this paper,we study conformal transformations in complex Finsler geometry.We first prove that two weakly Kahler Finsler metrics cannot be conformal.Moreover,we give a necessary and sufficient condition for a strongly pseudoconvex complex Finsler metric to be locally conformal weakly Kahler Finsler.Finally,we discuss conformal transformations of a strongly pseudoconvex complex Finsler metric,which preserve the geodesics,holomorphic S-curvatures and mean Landsberg tensors. | Hongjun Li Chunhui Qiu Hongchuan Xia Guozhu Zhong | 2022 | Science China Mathematics2022，65，7： | 0 |
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