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| 1 | Effects of nitrogen ion implantation on Ca^(2+) concentration and membrane potential of pollen cell显示文摘The effects of low energy nitrogen ion implantation on Ca2+ concentration and membrane potential of illy (Mum davidii Duch) pollen cell have been studied. The results showed that the Ca2+ concentration was increased when pollen grain was implanted by nitrogen ion with energy 100 keV and dose 1013 ions/cm2. However, the increase of Ca2+ concentration was partly inhibited by the addition of Ca2+ channel inhibitor depending on dose. And nitrogen ion implantation caused depolarization of pollen cell membrane potential. In other words, membrane potential was increased, but the effect decreased by adding Ca2+ channel inhibitor. However, it was still significantly higher than the membrane potential of control cells. It was indicated that the depolarization of cell membrane potential opened the calcium channel on the membrane that caused the increasing of intracel-lular calcium concentration. This might be an earlier step of the effect of low energy nitrogen ion implantation on pollen germination. | HUANG Zhonglian, JING Yanping, ZHU Guoli, LU Ting, ZHOU Hongyu & REN Haiyun1. Key Laboratory of Cell Proliferation and Regulation Biology of the Ministry of Education, Beijing Normal University, Beijing 100875, China 2. Key Laboratory of Plant Physiology and Biochemistry of the Ministry of Agriculture, China Agriculture University, Beijing 100094, China 3. Institution of Low Energy Nuclear Physics, Beijing Normal University, Beijing 100875, China | 2001 | Chinese Science Bulletin2001，46，20： | 5 |
| 2 | A critical survey of technologies of large offshore wind farm integration: summary, advances, and perspectives显示文摘Offshore wind farms(OWFs)have received widespread attention for their abundant unexploited wind energy poten-tial and convenient locations conditions.They are rapidly developing towards having large capacity and being located further away from shore.It is thus necessary to explore effective power transmission technologies to connect large OWFs to onshore grids.At present,three types of power transmission technologies have been proposed for large OWF integration.They are:high voltage alternating current(HVAC)transmission,high voltage direct current(HVDC)transmission,and low-frequency alternating current(LFAC)or fractional frequency alternating current transmission.This work undertakes a comprehensive review of grid connection technologies for large OWF integration.Compared with previous reviews,a more exhaustive summary is provided to elaborate HVAC,LFAC,and five HVDC topologies,consisting of line-commutated converter HVDC,voltage source converter HVDC,hybrid-HVDC,diode rectifier-based HVDC,and all DC transmission systems.The fault ride-through technologies of the grid connection schemes are also presented in detail to provide research references and guidelines for researchers.In addition,a comprehensive evalu-ation of the seven grid connection technologies for large OWFs is proposed based on eight specific indicators.Finally,eight conclusions and six perspectives are outlined for future research in integrating large OWFs. | Bo Yang Bingqiang Liu Hongyu Zhou Jingbo Wang Wei Yao Shaocong Wu Hongchun Shu Yaxing Ren | 2022 | Protection and Control of Modern Power Systems2022，7，1： | 4 |
| 3 | Bacterial and cyanobacterial diversities determined by T-RFLP analyses in the Jiaozhou Bay显示文摘染色 epifluorescence 显微镜学和 T-RFLP 分析的 DAPI 的方法被用来在在 12 上在调查期间从 12stations 取样在内并且在 Jiaozhou 海湾外面的表面海水和 2004 年 9 月 13 日分析微生物引起的丰富和差异。全部的微生物的 Theabundance 在 10 ~ 的范围是 6 ~ 10 ~ 7 cells/cm~3,类似于那些在在世界上的适度的区域的围住 mostsemi 的海湾。最高微生物引起的密度发生在 Jiaozhou 海湾的东北部分,绕 Loushan 和 Licun 河的嘴,建议并且 theHongdao 水文化耕作区域污染的度和特征,与一起地理并且水文学效果,可以是在 Jiaozhou 海湾影响细菌的丰富和分发的重要决定因素。细菌的社区在内并且在 Jiaozhou 海湾外面能基于 T-RFLP 模式和簇分析被组织进三个班。在海湾嘴和外面的水隧道驻扎,例如 D1, D3, D5, D6 andD7,一起被组织代表在 Jiaozhou 海湾外面与环境交往的在外面细菌的社区。Jiaozhou 海湾,如此的 asA3, A5, B2 和 Y1 的最深处的方面的车站,一起被组织代表居住细菌社区。StationsC1, C3 和 C4 一起被组织并且可以代表在居住社区和外面的社区之间的过渡细菌的集合。然而,为 cyanobacterial 差异的盒子没有如此的一种定义关系,显示 cyanobacteria 对各种条件更灵活、能适应的事实。 | REN Jing DANG Hongyue SONG Linsheng SUN Song AN Liguo | 2006 | Acta Oceanologica Sinica2006，25，4： | 4 |
| 4 | CW interference mitigation in GNSS receiver based on frequency-locked loop显示文摘Global navigation satellite system(GNSS) receivers are highly susceptible to continuous wave(CW)interference because the received signals are extremely weak. Current interference mitigation techniques mainly use a notch filter or transform domain. This paper proposes a computationally effective algorithm based on a frequency-locked loop(FLL) to mitigate interference in GNSS receivers. The performance of the algorithm is validated through an analysis of the characteristics of the interference reduction filter and interference estimation precision. A Monte Carlo simulation is used to compare the proposed algorithm with various previous algorithms:the adaptive IIR notch filter, adaptive linear-phase FIR filter, and N-sigma DFT algorithm. The simulation results show that the proposed algorithm exhibits excellent interference estimation precision and superior antijamming performance compared with the conventional algorithms. | Hongyu REN Yongqing WANG Lei JIANG Siliang WU | 2016 | Science China(Information Sciences)2016，59，8： | 2 |
| 5 | Vertical Alignment of Anisotropic Fillers Assisted by Expansion Flow in Polymer Composites显示文摘Orientation control of anisotropic one-dimensional(1D)and two-dimensional(2D)materials in solutions is of great importance in many fields ranging from structural materials design,the thermal management,to energy storage.Achieving fine control of vertical alignment of anisotropic fillers(such as graphene,boron nitride(BN),and carbon fiber)remains challenging.This work presents a universal and scalable method for constructing vertically aligned structures of anisotropic fillers in composites assisted by the expansion flow(using2D BN platelets as a proof-of-concept).BN platelets in the silicone gel strip are oriented in a curved shape that includes vertical alignment in the central area and horizontal alignment close to strip surfaces.Due to the vertical orientation of BN in the central area of strips,a throughplane thermal conductivity as high as 5.65 W m^(-1) K^(-1) was obtained,which can be further improved to 6.54 W m^(-1) K^(-1) by combining BN and pitch-based carbon fibers.The expansion-flow-assisted alignment can be extended to the manufacture of a variety of polymer composites filled with 1D and 2D materials,which can find wide applications in batteries,electronics,and energy storage devices. | Hongyu Niu Haichang Guo Lei Kang Liucheng Ren Ruicong Lv Shulin Bai | 2022 | Nano-Micro Letters2022，14，9： | 2 |
| 6 | Optimization of pulsed-field gel electrophoresis for Legionella pneumophila subtyp- ing显示文摘 | Haijian Zhou Hongyu Ren Bingqing Zhu | 2010 | Applied and environmental microbilolgy2010，76，5： | 1 |
| 7 | GLUTAMINE REDUCES CYTOKINE RELEASE, ORGAN DAMAGE, AND MORTALITY IN A RAT MODEL OF ENDOTOXEMIA显示文摘 | Paul E. Wischmeyer Madelyn Kahana Rachel Wolfson Hongyu Ren Mark M. Musch Eugene B. Chang | 2001 | Shock2001，，5： | 1 |
| 8 | Polyaniline-based electrocatalysts through emulsion polymerization:Electrochemical and electrocatalytic performances显示文摘One of the major challenges associated with fuel cells is the design of highly efficient electrocatalysts to reduce the high overpotential of the oxygen reduction reaction(ORR). Here we report Polyaniline(PANI)based micro/nanomaterials with or without transition metals, prepared by the emulsion polymerization and subsequent heat treatment. PANI microspheres with the diameter of about 0.7 μm have been prepared in basic(NH3solution) condition, using two different types of surfactant(CTAB, SDS) as the stabilizer, ammonium persulphate(APS) as oxidant with aniline/surfactants molar ratio at 1/1 under the hydrothermal treatment. PANI nanorods, Fe–PANI, and Fe–Co–PANI have been synthesized in acidic(HCl)medium with aniline/surfactants molar ratio at 1/2 and polymerization carried out without stirring for24 h. Products mainly Fe–Co–PANI have shown high current density with increasing sweep rate and excellent specific capacitance 1753 F/g at the scan rate of 1 m V/s. Additionally, it has shown high thermal stability by thermogravimetric analysis(TGA). Fe–PANI has been investigated for excellent performance toward ORR with four electron selectivity in the basic electrolyte. The PANI-based catalysts from emulsion polymerization demonstrate that the method is valuable for making non-precious metal heterogeneous electrocatalysts for ORR or energy storage and conversion technology. | Shehnaz Xuedan Song Suzhen Ren Ying Yang Yanan Guo Hongyu Jing Qing Mao Ce Hao | 2017 | Journal of Energy Chemistry2017，26，1： | 1 |
| 9 | Design, synthesis, and biological evaluation of a series of simple and novel potential antimalarial compounds显示文摘 | Hongyu Ren Shannon Grady Daniela Gamenara Horacio Heinzen Patrick Moyna Simon L. Croft Howard Kendrick Vanessa Yardley Guillermo Moyna | 2001 | Bioorganic & Medicinal Chemistry Letters2001，，14： | 1 |
| 10 | Low Spurious Noise Frequency Synthesis Based On ADDS Driven Wideband PLL Architecture 显示文摘 | Wang Hongyu Wang Haofei Ren Lixiang | 2013 | Journal of Beijing Institute of Technology (English Edition)2013，22，4： | 1 |
| 11 | Effects of UV-B Radiation and Water Stress on Soybean Yield显示文摘Soybean Dongnong 47 was subjected to the experiments of increasing UV-B radiation and water stress on soybean yield components in different growth periods. The results showed that 100-seed weight greatly increased during the early stage of pod filling in the treatment of weak UV-B radiation,seed number per plant as well as seed weight per plant and Dongnong47 yield also increased,while the yield and yield components of Dongnong47 during the blossom to mature period were negatively affected in the treatment of intensive UV-B radiation. 100-seed weight of Dongnong47 all increased in the double factor treatments of UV-B radiation and water stress,with the drought intensified,seed number per plant,seed weight per plant and yield of Dongnong47 decreased,the change of 100-seed weight were various and the antagonistic action of UV-B radiation and water stress were related with their intensity. | REN Hongyu XU Haiming LI Dongming HUANG Rui WANG Licheng | 2009 | Journal of Northeast Agricultural University(English Edition)2009，16，3： | 1 |
| 12 | Light-triggered NO-releasing nanoparticles for treating mice with liver fibrosis显示文摘Liver fibrosis, resulting from chronic liver damage and characterized by the accumulation of extracellular matrix (ECM) proteins, is a characteristic of most types of chronic liver diseases. The activation of hepatic stellate cells (HSC) is considered an essential pathological hallmark in liver fibrosis. Although nitric oxide (NO) can effectively induce HSC apoptosis, the systemic administration of NO is ineffective and may cause severe complications such as hypotension. To overcome this limitation, nanoparticles were designed to target HSCs and release NO locally under the exposure of near infrared light (NIR). To achieve this, upconversion nanoparticle (UCNP) cores were enveloped in mesoporous silica shells (UCNP@mSiO2), which were modified with hyaluronic acid (HA-UCNP@mSiO2) and Roussin’s black salt (RBS). HA molecules recognize and bind to CD44 proteins, which are overexpressed on activated HSCs. Under exposure to a 980-nm NIR laser, the UCNP cores convert the 980-nm wavelength into ultraviolet (UV) light, which then energizes the RBS (NO donors), resulting in an efficient release of NO inside of the HSCs. Once released, NO triggers HSC apoptosis and reverses the liver fibrosis. This targeted and controlled release method provides the theoretical and experimental basis for novel therapeutic approaches to treat hepatic fibrosis. | Hongxia Liang Zhenhua Li Zhigang Ren Qiaodi Jia Linna Guo Shasha Li Hongyu Zhang Shiqi Hu Dashuai Zhu Deliang Shen Zujiang Yu Ke Cheng | 2020 | Nano Research2020，13，8： | 1 |
| 13 | Enhanced photo-hydrogen production of Rhodopseudomonas Faecalis RLD-53 by EDTA addition显示文摘 | REN Hongyu LIU Bingfeng DING Jie | 2012 | International Journal of Hydrogen Energy2012，37，： | 1 |
| 14 | Differential proteome and transcriptome analysis of porcine skeletal muscle during development显示文摘 | Yongjie Xu Hui Qian Xiaoting Feng Yuanzhu Xiong Minggang Lei Zhuqing Ren Bo Zuo Dequan Xu Yun Ma Hongyu Yuan | 2012 | Journal of Proteomics2012，，7： | 1 |
| 15 | Phthalimide and Naphthalimide end-Capped Diketopyrrolopyrrole for Organic Photovoltaic Applications显示文摘二个小分子作为终端作为中央强壮的领受人单位和 phthalimide/naphthalimide 与一个 DPP 核心说出 PI-DPP 和 NI-DPP 弱领受人被设计并且综合。热行为,光、电气化学的性质,以及这二材料的光电的表演上的终端 phthalimide/naphthalimide 单位的效果系统地被学习。周期的 voltammetry 表明两个分子的最低没有住的分子的 orbitals (LUMO )(^-3.6 eV ) 对普通电子施主(P3HT ) 和领受人(PCBM ) 中间。当与 PCBM 相配时,当与 P3HT 相配时,在在 DPP 和 PCBM 之间,以及在 P3HT 和 DPP 之间的足够的驱动力应该为激子分离被创造的地方,这显示 PI-DPP 和 NI-DPP 可以特别地用作电子施主,并且作为电子领受人。用作电子施主材料, PI-DPP 和 NI-DPP 设备由分别地与 PCBM 相配展出了 0.90% 和 0.76% 的低力量变换效率(PCE ) 。并且 NI-DPP 的潜力的初步的评估作为施主材料,和 P3HT 用 P3HT 作为电子领受人材料被执行: NI-DPP 设备显示出0.6%的 PCE ,与开的电路电压( V 0.7 V 的 OC ),短路电流密度( J 1.91 mAcm -2,和45%的一个fill 因素( FF )的 SC )。 | Ming Chen Chenchen Du Xiaolei Ren Maoheng Yi Jinduo Yi Chufeng Chen Feng Liu Minjie Li Changqi Ma Hongyu Wang | 2017 | Chinese Journal of Chemistry2017，35，9： | 1 |
| 16 | miR-338-5p inhibits cell growth and migration via inhibition of the METTL3/m6A/c-Myc pathway in lung cancer显示文摘Lung cancer is a common type of cancer that causes a very large public health burden worldwide.Achieving a better understanding of the molecular mechanism underlying the progression of lung cancer is of benefit for the diagnosis,prognosis,and treatment of lung cancer.Here,we first identified dramatically decreased expression of miR-338-5p in lung cancer tissues and cells using quantitative polymerase chain reaction(qPCR)analysis.We then revealed that miR-338-5p inhibited the cell growth and migration of lung cancer cells using cell counting kit 8(CCK8),EdU,and Transwell analysis.Furthermore,we demonstrated that miR-338-5p inhibited METTL3 expression by qPCR,western blot analysis,and luciferase reporter assay,while upregulation of METTL3 alleviated the role of miR-338-5p in lung cancer cells.We also showed that METTL3 promoted c-Myc expression by increasing the m6A modification of c-Myc,and overexpression of c-Myc restored the inhibition of cell growth and migration of lung cancer cells induced by METTL3 silencing.Ultimately,this research illustrated that modification of the miR-338-5p/METTL3/c-Myc pathway affected cellular progression in lung cancer cells.Collectively,our study revealed the underlying mechanism of miR-338-5p in lung cancer,providing a novel regulatory pathway in lung cancer.There is potential for this pathway to serve as a diagnostic,prognostic,and therapeutic biomarker for lung cancer. | Hongyu Wu Fangjuan Li Ren Zhu | 2021 | Acta Biochimica et Biophysica Sinica2021，53，3： | 1 |
| 17 | Developer recommendation on bug commenting:a ranking approach for the developer crowd显示文摘A bug tracking system provides a collaborative platform for the developer crowd. After a bug report is submitted, developers can make comments to supplement the details of the bug report. Due to the large number of developers and bug reports, it is hard to determine which developer(also called commenter) is able to comment on a particular bug report. We refer to the problem of recommending developers for commenting on bug reports as commenter recommendation. In this paper, we perform an empirical analysis on commenter recommendation based on five-year bug reports of four open source projects. First, we preliminarily analyze bug comments and commenters in three categories, the relationship between commenters and fixers, the data scale of comments, and the collaboration on bug commenting. Second, we design a recommendation approach via ranking developers in the crowd to reduce the manual effort of identifying commenters. In this approach,we formulize the commenter recommendation problem as a multi-label recommendation task and leverage both developer collaboration and bug content to find out appropriate commenters. Experimental results show that our approach can effectively recommend commenters; 41% to 75% of the recall value is achieved for top-10 recommendation. Our empirical analysis on bug commenting can help developers understand and improve the process of fixing bugs. | Jifeng XUAN He JIANG Hongyu ZHANG Zhilei REN | 2017 | Science China(Information Sciences)2017，60，7： | 1 |
| 18 | Liver cirrhosis as a predisposing condition for Legionnaires’ disease: a report of four laboratory-confirmed cases from China显示文摘 | Tian Qin Jie Xia Hongyu Ren Haijian Zhou Bo Tang Zhujun Shao | 2012 | Journal of Medical Microbiology (Pt )2012，，7： | 1 |
| 19 | Differential Expression Analysis of Proteins Regulated by Rare Earth Cerium in Soybean Leaves at Seedling Stage显示文摘This study was to explore the functional mechanism of rare earth regulating soybean leaves and the characteristics and functions of differentially expressed proteins under the regulation of rare earth. In this study, Dongnong 42 was used as material, and 30 mg·L^(-1) CeCl_(3) solution was sprayed on soybean leaves at the seedling stage. Tandem mass tag(TMT) quantitative proteomics technique and bioinformatics analysis were used to identify soybean leaf proteins. A total of 8 510 proteins were identified, and 127 differentially expressed proteins(DEPs) in response to rare earth cerium regulation were identified, among which 64 were upregulated and 63 were down-regulated. The gene ontology(GO) annotation indicated that DEPs were mainly involved in metabolic process, cellular process, response to stimulus, biological regulation, and response to a stimulus;DEPs in cell module categories were mainly involved in cells, cell part, organelle, membrane, membrane part, organelle par, and protein-containing complex;DEPs in molecular functional categories were mainly involved in catalytic activity, binding and antioxidant activity. Kyoto encyclopedia of genes and genomes(KEGG) pathway significantly enriched starch and sucrose metabolism, glycolysis/gluconeogenesis, galactose metabolism, pentose phosphate pathway, and MAPK signaling pathway-plant. These DEPs were mainly involved in photosynthesis, glucose metabolism and stress response. Forty-six differential protein interaction networks were identified by protein interaction network analysis. This experiment provided a reference for studies of the mechanism of rare earth cerium regulating soybean leaf function from the proteomic perspective. | Ren Hongyu Zhang Tianren Miao Yanli Li Haoyang Zhang Shuying Zhang Xingwen | 2024 | Journal of Northeast Agricultural University(English Edition)2024，31，1： | 0 |
| 20 | Current research status of tumor cell biomarker detection显示文摘With the annual increases in the morbidity and mortality rates of tumors,the use of biomarkers for early diagnosis and real-time monitoring of tumor cells is of great importance.Biomarkers used for tumor cell detection in body fluids include circulating tumor cells,nucleic acids,protein markers,and extracellular vesicles.Among them,circulating tumor cells,circulating tumor DNA,and exosomes have high potential for the prediction,diagnosis,and prognosis of tumor diseases due to the large amount of valuable information on tumor characteristics and evolution;in addition,in situ monitoring of telomerase and miRNA in living cells has been the topic of extensive research to understand tumor development in real time.Various techniques,such as enzyme-linked immunosorbent assays,immunoblotting,and mass spectrometry,have been widely used for the detection of these markers.Among them,the detection of tumor cell markers in body fluids based on electrochemical biosensors and fluorescence signal analysis is highly preferred because of its high sensitivity,rapid detection and portable operation.Herein,we summarize recent research progress in the detection of tumor cell biomarkers in body fluids using electrochemical and fluorescence biosensors,outline the current research status of in situ fluorescence monitoring and the analysis of tumor markers in living cells,and discuss the technical challenges for their practical clinical application to provide a reference for the development of new tumor marker detection methods. | Liying Jiang Xinyi Lin Fenghua Chen Xiaoyun Qin Yanxia Yan Linjiao Ren Hongyu Yu Lingqian Chang ang Wang | 2023 | Microsystems & Nanoengineering2023，9，5： | 0 |
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