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| 1 | Noninvasive assessment of portal hypertension in cirrhosis:Liver stiffness and beyond显示文摘Liver stiffness measurement(LSM)is a good,but still limited tool to noninvasively assess complications and prognosis in patients with advanced liver disease.This review aims to consider the role of LSM for the diagnosis of portal hypertension-related complications and for assessment of prognosis in cirrhotic patients,and to highlight the drawbacks as well as some alternatives for improving the performance.Hence,this field is far from being closed,and deserves more attention.There is still a place for more carefully designed studies to find new,innovative and reliable approaches. | Horia Stefanescu Bogdan Procopet | 2014 | World Journal of Gastroenterology2014，20，45： | 9 |
| 2 | 大气二氧化氮与每日总死亡率、心血管和呼吸系统疾病死亡率的短期关联:398个城市的多中心分析显示文摘目的:采用统一的分析方案,评估全球多个国家/地区的二氧化氮(NO_(2))与总死亡率、心血管和呼吸系统疾病死亡率之间的短期关联。研究设计:采用两阶段的时间序列分析方法、过度离散的广义线性模型和多水平meta分析。研究地点:22个低到高收入国家/地区的398个城市。主要结局指标:1973—2018年逐日总死亡人数(6280万人)、心血管疾病死亡人数(1970万人)和呼吸系统疾病死亡人数(550万人)。结果:平均而言,NO_(2)浓度在滞后1天(前1天)每增加10μg/m^(3),会导致总死亡率、心血管和呼吸系统疾病死亡率分别增加0.46%(95%可信区间0.36%~0.57%)、0.37%(0.22%~0.51%)、0.47%(0.21%~0.72%)。在对共污染物(PM_(10)、PM_(2.5)、臭氧、二氧化硫和一氧化碳)进行调整后,这些关联仍然很稳定。所有3种死因的暴露-反应曲线几乎是线性的,没有明显的阈值。在398个城市中,可归因于高过假定零水平的NO_(2)浓度造成的死亡比例为1.23%(95%可信区间0.96%~1.51%)。结论:这项多中心研究提供了关于NO_(2)短期暴露与总死亡率、心血管和呼吸系统死亡风险之间的独立和线性关联的关键证据,说明通过加强NO_(2)的控制和监管限制标准,可获得人群水平的健康收益。 | 孟夏 刘聪(校) 陈仁杰 郑湃(译) 阚海东(校) Francesco Sera Ana Vicedo-Cabrera Ai Milojevic Maria Guo Yuming Tong Shilu Micheline de Sousa Zanotti Stagliorio Coelh Paulo Hilario Nascimento Saldiva Eric Lavigne Patricia Matus Correa Nicolas Valdes Ortega Samuel Osorio Garcia Jan Kysely Ales Urban Hans Orru Marek Maasikmets Jouni J K Jaakkola Niilo Ryti Veronika Huber Alexandra Schneider Klea Katsouyanni Antonis Analitis Masahiro Hashizume Yasushi Honda Chris Fook Sheng Ng Baltazar Nunes João Paulo Teixeira Iulian Horia Holobaca Simona Fratianni Ho Kim Aurelio Tobias Carmeníniguez Bertil Forsberg ChristoferÅström Martina S Ragettli Yue-Liang Leon Guo Shih-Chun Pan Shanshan Li Michelle L Bell Antonella Zanobetti Joel Schwartz Tangchun Wu Antonio Gasparrini | 2021 | 英国医学杂志中文版2021，24，8： | 7 |
| 3 | 叶轮不同叶片对离心泵内流道流场的影响显示文摘对离心泵进行三维建模,并对内部流场进行数值模拟.采用'仿真-实验'法验证了六叶片离心泵流场仿真的合理性,研究了叶轮上不同叶片数对内流道流场的影响.数值模拟原理为大涡模拟,通过网格直接模拟大尺度的紊流运动,同时,利用次网格尺度模型来模拟小尺度紊流运动对大尺度紊流运动所造成的影响.大涡模拟可以获得雷诺时均模拟法无法获得的流场细微图像.模拟结果表明:离心泵叶片数量过多,会使叶片表面摩擦力做功加大,使得离心泵出口处的总功减少,从而降低离心泵的扬程和效率.经过模拟实验研究分析发现,当叶片数为5时,离心泵流场的综合性能最好,运行效率最高,湍流强度低,流场稳定性最好. | 齐凤莲 刘冠诚 Horia Abaitancei 王永章 | 2018 | 中国工程机械学报2018，16，5： | 6 |
| 4 | Diagnostic challenges in non-cirrhotic portal hypertension-porto sinusoidal vascular disease显示文摘Non-cirrhotic portal hypertension consists of a group of diseases characterized by signs and complications of portal hypertension,which differ from cirrhosis through histological alterations,hemodynamic characterization and,clinical outcome.Because of the similarities in clinical presentation and imaging signs,frequently these patients,and particularly those with porto-sinusoidal vascular disease(PSVD),are misdiagnosed as having liver cirrhosis and thus raising difficulties in their diagnosis.The most challenging differentiation to be considered is between PSVD and cirrhosis and,although not pathognomonic,liver biopsy is still the standard of diagnosis.Although they still require extended validation before being broadly used,new non-invasive methods for the diagnosis of porto-sinusoidal vascular disease,like transient elastography,contrast-enhanced ultrasound or metabolomic profiling,have shown promising results.Another issue is the differentiation between PSVD and chronic extrahepatic portal vein obstruction,especially now when it is known that 40%of patients suffering from PSVD develop portal vein thrombosis.In this particular case,once the portal vein thrombosis occurred,the diagnosis of PSVD is impossible according to the current guidelines.Moreover,so far,the differentiation between PSVD and sinusoidal obstruction syndrome has not been clear so far in particular circumstances.In this review we highlighted the diagnostic challenges regarding the PSVD,as well as the current techniques used in the evaluation of these patients. | Oana Nicoara-Farcau Ioana Rusu Horia Stefanescu Marcel Tanțau Radu Ion Badea Bogdan Procopet | 2020 | World Journal of Gastroenterology2020，26，22： | 4 |
| 5 | Endoscopic Optical Coherence Tomography (OCT): Advances in Gastrointestinal Imaging显示文摘 | Tejas S. Kirtane Mihir S. Wagh Horia Stef?nescu | 2014 | Gastroenterology Research and Practice2014，，： | 1 |
| 6 | Magnetic GMI sensor for detection of blomolecules显示文摘 | Chirlae Horia | 2005 | J of Magnetism and Magnetic Materials2005，293，： | 1 |
| 7 | Numerical Simulation of Impinging Jets with Application to Downbursts 显示文摘 | Jongdae K Horia H | 2007 | Journal of Wind Engineering and Industrial Aerodynamics2007，，95： | 1 |
| 8 | Comparison of stearidonic acid and α-linolenic acid on PGE2 production and COX-2 protein levels in MDA-MB-231 breast cancer cell cul- tures显示文摘 | Horia E Watkins B A | 2005 | Nutr Biochem2005，16，3： | 1 |
| 9 | 2013 Ambulatory Blood Pressure Monitoring Recommendations for the Diagnosis of Adult Hypertension, Assessment of Cardiovascular and other Hypertension-associated Risk, and Attainment of Therapeutic Goals显示文摘 | Ramón C. Hermida Michael H. Smolensky Diana E. Ayala Francesco Portaluppi Juan J. Crespo Fabio Fabbian Erhard Haus Roberto Manfredini Artemio Mojón Ana Moyá Luis Pi?eiro María T. Ríos Alfonso Otero Horia Balan José R. Fernández | 2013 | Chronobiology International2013，，3： | 1 |
| 10 | Geo - electrical investigations by means of resistivity methods in karst areas in Romania 显示文摘 | Mitrofan Horia Povara Ioan Mafteiu Mihai | 2008 | Environmental Geology2008，55，2： | 1 |
| 11 | Activation of thrombosis and fibrinolysis following brain infarction显示文摘 | Kataoka S Hirose G HoriA | 2000 | J Neurol Sci2000，181，： | 1 |
| 12 | First experiences invideo-assisted thoracic surgical pacemaker implantation显示文摘 | Oliver O Horia S Thomas B | 2004 | Z Herz-Thorax-Gefabchir2004，18，4： | 1 |
| 13 | Numerical simulations of impinging jet swith application to downdrafts显示文摘 | JONGDAE K1M HORIA HANGAN | 2007 | Journal of Wind Engineering and Industrial Aerodynamics2007，95，27： | 1 |
| 14 | Wind - induced forces on eaves of low buildings显示文摘 | Theodore S Horia L | 1994 | Journal of Wind Engineering and IndustrialAerodynamics1994，，52： | 1 |
| 15 | Complementary actions of docosahexaenoic acid and genistein on COX-2, PGE2 and invasiveness in MDA-MB-231 breast cancer cells显示文摘 | Horia E Watkins BA | 2007 | Carcinogenesis2007，28，4： | 1 |
| 16 | Numerical simulations of impinging jets with application to downdrafts显示文摘 | Jongdae Kim Horia Hangan | 2007 | Journal of Wind Engineering and Industrial Aerodynamics2007，95，4： | 1 |
| 17 | Electron beam synthesis and characterization of poly (vinyl alcohol)/montmorillonite nanocomposites显示文摘 | Safaa G Abd Alla Horia M Nizam El-Din Abdel Wahab M El-Naggar | 2006 | Journal of Applied Polymer Science2006，102，2： | 1 |
| 18 | Suppressionofsolidtumorgrowthbyimmunoneutralizingmonoclonalantibodyagainsthumanbasicfibroblastgrowthfator显示文摘 | HoriA SasadaR MatsutaniE etal | 1991 | CaacerRes1991，51，6： | 1 |
| 19 | Magnetic GMI sensor for detection of detection of biomolecules 显示文摘 | Horia Chiriac Mihai Tibu | 2005 | Journal of Magnetism and Magnetic Materials2005，293，： | 1 |
| 20 | 'Photovoltai applications'显示文摘 | Horia Andrei Valentin Dogaru Ulieru and Gianfranco Chicco | 2007 | Journal of Materials Processing Technology2007，，181： | 1 |
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