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| 1 | Characteristics,clinical outcomes and factors influencing mortality of patients with melioidosis in southern Thailand:a 10-year retrospective study显示文摘Objective:To study characteristics,clinical outcomes and factors influencing mortality of patients afflicted with melioidosis.Methods:A total of 134 patients were retrospectively analyzed with a microbiologically-confirmed diagnosis of melioidosis,during the period from January 2002 to June 2011 at Songklanagarind Hospital,a tertiary care hospital in southern Thailand.Results:The prevalence of melioidosis among admitted patients was 36.8 per100000 in patients.The median age was 49 years and they were predominantly male.The most common underlying disease was diabetes mellitus(47.01%).The majority of cases(50%)had localized infection.The rates of multifocal,bacteremic,and disseminated infections were12.7%.23.1%.and 14.2%.respectively.The lungs were the most common organ afflicted,resulting in infection(24.63%).Splenic abscess as well as liver abscess accounted for 20.90%and 19.40%.respectively.A total of one eighth of the patients had septic shock at presentation.The overall mortality rate was 8.96%.The factors influencing mortality were pneumonia,septic shock,a positive blood culture for Burkholderia pseudomallei.superimposing with nosocomial infection and inappropriate antibiotic administration.Conclusions:Melioidosis is not uncommon in southern Thailand.The mortality of patients with pneumonia,bacteremia and septic shock is relatively high.Appropriate antibiotics,initially,will improve outcomes. | Chaitong Churuangsuk Sarunyou Chusri Thanaporn Hortiwakul Boonsri Charernmak Kachornsakdi Silpapojakul | 2016 | Asian Pacific Journal of Tropical Medicine2016，9，3： | 3 |
| 2 | Distribution of azithromycin into brain tissue, cerebrospinal fluid, and aqueous humor of the eye 显示文摘 | JARURATANASIRIKUL S HORTIWAKUL R TANTISARASART T | 1996 | Antimicrob Agents Chemother1996，40，： | 1 |
| 3 | Distribution of azithromycin into brain tissue,cerebrospinalfluid,and aqueous humor of the eye显示文摘 | Jaruratanasirikul S Hortiwakul R Tantisarasart T? | 1996 | Antimicrob AgentsChemother1996，40，： | 1 |
| 4 | Nosoeomial blood- stream infection in Songklanagarind Hospital: outcome and factors influencing prognosis显示文摘 | Hortiwakul T Nagij S Chusri S | 2012 | J Med Assoc Thai2012，95，2： | 1 |
| 5 | Nosocomial bloodstream infection in Songklanagarind Hospital:outcome and factors influencing prognosis显示文摘 | Hortiwakul T Nagij S Chusri S | 2012 | J Med Assoc Thai2012，95，2： | 1 |
| 6 | Nosocomial bloodstream infection in Songklanagarind Hospital:outcome and factors influencing prognosis显示文摘 | Hortiwakul T Nagij S Chusri S | 2012 | J Med Assoc Thai2012，95，2： | 1 |
| 7 | Nosoeomial bloodstream infection in Songklanagarind Hospital: outcome and factors influencing prognosis 显示文摘 | Hortiwakul T Nagij S Chusri S | 2012 | J Med Assoc Thai2012，95，2： | 1 |
| 8 | Nosocomial bloodstream infection in Songklanagarind Hospital:outcome and factors influencing prognosis显示文摘 | Hortiwakul T Nagij S Chusri S | | 0，，： | 1 |
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