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| 1 | In vitro activity of moxifloxacin and piperacillin/sulbactam against pathogens of acute cholangitis显示文摘AIM: To analyze the in vitro activity of moxifloxacin and piperacillin/sulbactam against pathogens isolated from patients with acute cholangitis. METHODS: In this prospective study a total of 65 patients with acute cholangitis due to biliary stone obstruction (n = 7), benign biliary stricture (n = 16), and malignant biliary stricture (n = 42) were investigated with regard to spectrum of bacterial infection and antibiotic resistance. Pathogens were isolated from bile cultures in all study patients. In 22 febrile patients, blood cultures were also obtained. In vitro activity of moxifloxacin and piperacillin/ sulbactam was determined by agar diffusion. RESULTS: Thirty-one out of 65 patients had positive bile and/or blood cultures. In 31 patients, 63 isolates with 17 different species were identified. The predominant strains were Enterococcus species (26/63), E.coli (13/63) and Klebsiella species (8/63). A comparable in vitro activity of moxifloxacin and piperacillin/sulbactam was observed for E.coli and Klebsiella species. In contrast, Enterococcus species had higher resistances towards moxifloxacin. Overall bacteria showed antibiotic resistances in vitro of 34.9% for piperacillin/sulbactam and 36.5% for moxifloxacin.CONCLUSION: Enterococcus species , E.coli and Klebsiella species were the most common bacteria isolated from bile and/or blood from patients with acute cholangitis. Overall, a mixed infection with several species was observed, and bacteria showed a comparable in vitro activity for piperacillin/sulbactam and moxifloxacin. | Andreas Weber Wolfgang Huber Klaus Kamereck Philipp Winkle Petra Voland Hans Weidenbach Roland M Schmid Christian Prinz | 2008 | World Journal of Gastroenterology2008，14，20： | 18 |
| 2 | 应用无标定激光诱导击穿光谱法分析钢铁工业中氧化物材料显示文摘激光诱导击穿光谱技术是一种具有吸引力的快速定量表征材料的方法,可用于工业过程的在线监控。本文报告了该技术在多元氧化物材料分析上应用。采用激光诱导击穿光谱技术分析钢工业生产的炉渣和混合氧化物试料,然后以无标定法测定其中氧化物的浓度,结果发现,对于本研究所涉及的材料,无标定激光诱导击穿光谱方法的测定浓度值与参考值一致,大部分样品和氧化物组分的绝对误差小于2%(质量分数),大范围改变测定参数时浓度值保持稳定。研究结果表明激光诱导击穿光谱技术作为钢铁工业中新型的分析测试技术具有很大潜力。 | PEDARNIG Johannes D HEITZ Johannes PRAHER Bernhard KOLMHOFER Philipp HUBER Norbert RSSLER Roman WOLFMEIR Hermann ARENHOLZ Enno | 2012 | 冶金分析2012，32，8： | 2 |
| 3 | Radiotherapy-induced heart disease:a review of the literature显示文摘Radiotherapy as one of the four pillars of cancer therapy plays a critical role in the multimodal treatment of thoracic cancers.Due to significant improvements in overall cancer survival,radiotherapy-induced heart disease(RIHD)has become an increasingly recognized adverse reaction which contributes to major radiationassociated toxicities including non-malignant death.This is especially relevant for patients suffering from diseases with excellent prognosis such as breast cancer or Hodgkin’s lymphoma,since RIHD may occur decades after radiotherapy.Preclinical studies have enriched our knowledge of many potential mechanisms by which thoracic radiotherapy induces heart injury.Epidemiological findings in humans reveal that irradiation might increase the risk of cardiac disease at even lower doses than previously assumed.Recent preclinical studies have identified non-invasive methods for evaluation of RIHD.Furthermore,potential options preventing or at least attenuating RIHD have been developed.Ongoing research may enrich our limited knowledge about biological mechanisms of RIHD,identify non-invasive early detection biomarkers and investigate potential treatment options that might attenuate or prevent these unwanted side effects.Here,we present a comprehensive review about the published literature regarding clinical manifestation and pathological alterations in RIHD.Biological mechanisms and treatment options are outlined,and challenges in RIHD treatment are summarized. | Bingwen Zou Julius Philipp Schuster Kerun Niu Qianyi Huang Alexander Rühle Peter Ernst Huber | 2019 | Precision Clinical Medicine2019，2，4： | 2 |
| 4 | Biological treatment of ammonium-rich wastewater by partical nitritation and subsequent anaerobic ammonium oxidation (anammox) in a pilot plant 显示文摘 | Christian Fux Marc Boethler Philipp Huber | 2002 | Biotechnology2002，99，： | 1 |
| 5 | Biological treatment of ammonium-rich wastewater by partical nitritation and subsequent anaerobic ammonium oxidation (anammox) in a pilot plant显示文摘 | Christian Fux Marc Boethler Philipp Huber | 2002 | Biotechnology2002，99，： | 1 |
| 6 | Does the cement stiffness affect fatigue fracture strength of vertebrae after cement augmentation in osteoporotic patients?显示文摘 | Jan Philipp Kolb Rebecca A. Kueny Klaus Püschel Andreas Boger Johannes M. Rueger Michael M. Morlock Gerd Huber Wolfgang Lehmann | 2013 | European Spine Journal2013，，7： | 1 |
| 7 | Does the cement stiffness affect fatigue fracture strength of vertebrae after cement augmentation in osteoporotic patients?显示文摘 | Jan Philipp Kolb Rebecca A. Kueny Klaus Püschel Andreas Boger Johannes M. Rueger Michael M. Morlock Gerd Huber Wolfgang Lehmann | 2013 | European Spine Journal2013，，7： | 1 |
| 8 | Biologi- cal treatment of ammonium-rich wastewater by partial ni- tritation and subsequent anaerobic ammonium oxidation (anammox) in a pilot plant显示文摘 | Christian Fux Marc Boehler Philipp Huber | 2002 | Journal of Bioteehnology2002，99，3： | 1 |
| 9 | Neoadjuvant radiochemotherapy for locally advanced gastric cancer: Long-term results of a phase I trial显示文摘 | Abdelkarim S. Allal Daniel Zwahlen Marie-Anne Bründler Raymond de Peyer Philippe Morel Olivier Huber Arnaud D. Roth | 2005 | International Journal of Radiation Oncology, Biology, Physics2005，，5： | 1 |
| 10 | How to limit radial artery spasm during percutaneous coronary interventions: The spasmolytic agents to avoid spasm during transradial percutaneous coronary interventions (SPASM3) study显示文摘 | Julien Rosencher Aurès Cha?b Franck Barbou Marc‐Antoine Arnould Arthur Huber Emmanuel Salengro Arnaud Jégou Philippe Allouch Stéphane Zuily Fadila Mihoub Olivier Varenne | 2014 | Cathet. Cardiovasc. Intervent2014，，5： | 1 |
| 11 | Biological treatment of ammonium-rich wastewater by partial nitritation and subsequent anaerobic ammonium oxidation (anammox) in a pilot plant显示文摘 | Christian Fux Mare Boehler Philipp Huber | 2002 | Journal of Bioteehology2002，99，3： | 1 |
| 12 | TCT-412 Diltiazem, verapamil or dinitrate isosorbid for prevention of radial artery spasm in percutaneous coronary intervention显示文摘 | Julien Rosencher Arthur Huber Aures Chaib Jacques Monsegu Marc Antoine Arnould Philippe Allouch Arnaud Jegou Emmanuel Salengro Patrick Schiano Olivier Varenne | 2012 | Journal of the American College of Cardiology2012，，17： | 1 |
| 13 | 显示文摘 | Boehler Marc Huber Philipp | 2002 | Journal of Biotechnology2002，99，3： | 1 |
| 14 | Cell Volume Regulatory Ion Channels in Cell Proliferation and Cell Death显示文摘 | Florian Lang Michael F?ller Karl Lang Philipp Lang Markus Ritter Alexey Vereninov Ildiko Szabo Stephan M. Huber Erich Gulbins | 2007 | Methods in Enzymology2007，，： | 1 |
| 15 | Biological treatment of ammonium-rich wastewater by partial nitritation and subsequent anaerobic ammonium oxidation (anammox) in a pilot plant显示文摘 | Christian Fux Marc Boehler Philipp Huber Irene Brunner Hansruedi Siegrist | 2002 | Journal of Biotechnology2002，，3： | 1 |
| 16 | Bleeding in acute coronary syndromes and percutaneous coronary interventions:Position paper by the working group on Tthrombosis of the European society of cardiology显示文摘 | Steg Philippe Gabriel Huber Kurt Andreotti Felicita | 2011 | European Heart Journal2011，32，15： | 1 |
| 17 | Effects of newly devised plasma lice comb on human hair显示文摘A plasma device was developed showing high potential for a pesticide-free treatment of pediculosis. As a first safety assessment of the device was presented earlier, this present paper focuses on the damage introduced to human hair during a plasma treatment for pediculosis control. Therefore, human hairs were treated repeatedly to assess the possible occurring damage developing with increasing treatment durations. To analyse the inflicted changes on human hair examinations using x-ray photoelectron spectroscopy(XPS/ESCA), scanning nearfield optical microscopy(SNOM) and scanning electron microscopy were conducted, to compare the modifications of surface chemistry and mechanical alterations. The investigations revealed a mild impact on the surface chemistry(XPS/SNOM), while more distinct morphological changes on the hair surface could be observed. The authors conclude that an effect of the plasma comb device on the hair during a real-life treatment is negligible, due to the very short contact times during a standard combing procedure for pediculosis control. | Lars TEN BOSCH Andreas HUBER Philipp SAUERBIER Robert KOHLER Georg AVRAMIDIS Wolfgang VIOL | 2019 | Plasma Science and Technology2019，21，12： | 0 |
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