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您的检索式：作者名="Hussein Daher"
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| 1 | Chemical composition and antioxidant activity of a Lebanese plant Euphorbia macroclada schyzoceras显示文摘Objective:To determine the chemical composition,total phenolic and total flavonoid contents ofthe crude extracts from leaves and stems of a Lebanese plantEuphorbia macroclada schyzoceras(E.macroclada),and to evaluate their antioxidant potential using DPPH,H2O2,and chelating offerrous ions tests.Methods:Quantification of the total phenolic and total flavonoid contents ofthe crude extracts from leaves and stems and the antioxidant activities were evaluated usingspectrophotometric analyses.The chemical composition has been estimated using differenttechniques such as IR,LC/MS and NMR.Results:Ethanolic extract from leaves ofE.macroclada was better than aqueous extract and showed higher content in total phenolic and total flavonoidthan found in the stems.On the other hand,using DPPH and H2O2tests,this extract from leavesshowed higher antioxidant capacity than aqueous extract.However,using the chelating of ferrousions test,the antioxidant activity of the aqueous extract of both stems and leaves was strongerthan that of ethanolic once.The chemical composition of the whole plant showed the presence ofsome aromatic compounds and fatty acids.Conclusions:Both ethanolic and water extracts fromboth parts of this plant are effective and have good antioxidant power.So,this plant can be usedin the prevention of a number of diseases related to oxidative stress. | Hussein Farhan Hassan Rammal Akram Hijazi Ahmad Daher Mohamad Reda Hussein Annan Ali Chokr Ali Bassal Bassam Badran | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，7： | 1 |
| 2 | The LEAFY floral regulator displays pioneer transcription factor properties显示文摘Pioneer transcription factors(TFs)are a special category of TFs with the capacity to bind to closed chromatin regions in which DNA is wrapped around histones and may be highly methylated.Subsequently,pioneer TFs are able to modify the chromatin state to initiate gene expression.In plants,LEAFY(LFY)is a master floral regulator and has been suggested to act as a pioneer TF in Arabidopsis.Here,we demonstrate that LFY is able to bind both methylated and non-methylated DNA using a combination of in vitro genomewide binding experiments and structural modeling.Comparisons between regions bound by LFY in vivo and chromatin accessibility data suggest that a subset of LFY bound regions is occupied by nucleosomes.We confirm that LFY is able to bind nucleosomal DNA in vitro using reconstituted nucleosomes.Finally,we show that constitutive LFY expression in seedling tissues is sufficient to induce chromatin accessibility in the LFY direct target genes APETALA1 and AGAMOUS.Taken together,our study suggests that LFY possesses key pioneer TF features that contribute to launching the floral gene expression program. | Xuelei Lai Romain Blanc-Mathieu Loïc GrandVuillemin Ying Huang Arnaud Stigliani Jeremy Lucas Emmanuel Thevenon Jeanne Loue-Manifel Laura Turchi Hussein Daher Eugenia Brun-Hernandez Gilles Vachon David Latrasse Moussa Benhamed Renaud Dumas Chloe Zubieta François Parcy | 2021 | Molecular Plant2021，14，5： | 0 |
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