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| 1 | Hepatolithiasis and intrahepatic cholangiocarcinoma: A review显示文摘Although the incidence of hepatolithiasis is decreasing as the pattern of gallstone disease changes in Asia, the prevalence of hepatolithiasis is persistently high, especially in Far Eastern countries. Hepatolithiasis is an established risk factor for cholangiocarcinoma(CCA), and chronic proliferative inflammation may be involved in biliary carcinogenesis and in inducing the upregulation of cell-proliferating factors. With the use of advanced imaging modalities, there has been much improvement in the management of hepatolithiasis and the diagnosis of hepatolithiasis-associated CCA(HLCCA). However, there are many problems in managing the strictures in hepatolithiasis and differentiating them from infiltrating types of CCA. Surgical resection is recommended in cases of single lobe hepatolithiasis with atrophy, uncontrolled stricture, symptom duration of more than 10 years, and long history of biliaryenteric anastomosis. Even after resection, patients should be followed with caution for development of HL-CCA, because HL-CCA is an independent prognostic factor for survival. It is not yet clear whether hepatic resection can reduce the occurrence of subsequent HL-CCA. Furthermore, there are no consistent findings regarding prediction of subsequent HL-CCA in patients with hepatolithiasis. In the management of hepatolithiasis, important factors are the reduction of recurrence of cholangitis and suspicion of unrecognized HL-CCA. | Hyo Jung Kim Jae Seon Kim Moon Kyung Joo Beom Jae Lee Ji Hoon Kim Jong Eun Yeon Jong-Jae Park Kwan Soo Byun Young-Tae Bak | 2015 | World Journal of Gastroenterology2015，21，48： | 63 |
| 2 | Prevalence of clonorchiasis in patients with gastrointestinal disease: A Korean nationwide multicenter survey显示文摘AIM: To investigate prevalence of Clonorchis sinensis in patients with gastrointestinal symptoms, and the relation of the infection to hepatobiliary diseases in 26 hospitals in Korea.METHODS: Consecutive patients who had been admitted to the Division of Gastroenterology with gastrointestinal symptoms were enrolled from March to April 2005. Of those who had been diagnosed with clonorchiasis, epidemiology and correlation between infection and hepatobiliary diseases were surveyed by questionnaire.RESULTS: Of 3080 patients with gastrointestinal diseases, 396 (12.9%) had clonorchiasis and 1140 patients (37.2%) had a history of eating raw freshwater fish. Of those with a history of raw freshwater fish ingestion, 238 (20.9%) patients had clonorchiasis. Cholangiocarcinoma was more prevalent in C. sinensis-infected patients than non-infected patients [34/396 (8.6%) vs 145/2684 (5.4%), P = 0.015]. Cholangiocarcinoma and clonorchiasis showed statistically significant positive cross-relation (P = 0.008). Choledocholithiasis, cholecystolithiasis, cholangitis, hepatocellular carcinoma, and biliary pancreatitis did not correlate with clonorchiasis.CONCLUSION: Infection rate of clonorchiasis was still high in patients with gastrointestinal diseases in Korea, and has not decreased very much during the last two decades. Cholangiocarcinoma was related to clonorchiasis, which suggested an etiological role for the parasite. | Ho Gak Kim Jimin Han Myung-Hwan Kim Kyu Hyun Cho Im Hee Shin Gwang Ha Kim Jae Seon Kim Jin Bong Kim Tae Nyeun Kim Tae Hyeon Kim Tae Hyo Kim Jae Woo Kim Ji Kon Ryu Young-Soo Moon Jong Ho Moon Sung Jae Park Chan Guk Park Sung-Jo Bang Chang Heon Yang Kyo-Sang Yoo Byung Moo Yoo Kyu Taek Lee Dong Ki Lee Byung Seok Lee Sang Soo Lee Seung Ok Lee Woo Jin Lee Chang Min Cho Young-Eun Joo Gab Jin Cheon Young Woo Choi Jae Bok Chung Yong Bum Yoon | 2009 | World Journal of Gastroenterology2009，15，1： | 15 |
| 3 | Usefulness of CA 19–9 for pancreatic cancer screening in patients with new-onset diabetes显示文摘Background: Generally, carbohydrate antigen 19–9(CA 19–9) is not useful for screening pancreatic cancer in the asymptomatic general population. This study aimed to evaluate the utility of CA 19–9 level as a screening indicator of pancreatic cancer in asymptomatic patients with new-onset diabetes.Methods: We retrospectively reviewed the medical records of patients who visited our health promotion center for health check-ups without cancer related symptoms from January 2005 to January 2014, and were newly diagnosed with diabetes mellitus(DM) within 2 years before their visit.Results: Of the 5111 asymptomatic patients with new-onset DM(<2 years) selected for analyses, 87(1.7%) eventually developed pancreatic cancer after the health check-up. In the subgroup of 322 patients with high total bilirubin levels(>1.7 mg/d L) at the screening time, 42(73.7%) of 57 patients with high CA19–9 levels(>37 IU/m L) had been diagnosed as pancreatic cancer during follow-up period and 12(4.5%)of 265 patients with normal CA 19–9 levels had finally developed pancreatic cancer(OR = 16.3). In the subgroup of 4789 patients with normal bilirubin levels, pancreatic cancer had been detected in 20(3.8%)of 522 patients with high CA 19–9 level, while only 13(0.3%) in 4267 patients with normal CA 19–9 levels(OR = 12.6), respectively.Conclusion: CA 19–9 levels after a diagnosis of new-onset DM could be a useful biomarker of pancreatic cancer, especially in patients with high serum bilirubin. | Jung Wan Choe Hyo Jung Kim Jae Seon Kim Jaehyung Cha Moon Kyung Joo Beom Jae Lee Jong-Jae Park Young-Tae Bak | 2018 | Hepatobiliary & Pancreatic Diseases International2018，17，3： | 6 |
| 4 | Neural dynamics model for structural optimization theory 显示文摘 | Adeli Hyo Seon Park | 1995 | Computer and Structure1995，57，3： | 1 |
| 5 | Influence of anemia on tumor response to preoperative chemoradiotherapy for locally advanced rectal cancer显示文摘 | Seong Dae Lee Ji Won Park Kui Seon Park Seok-Byung Lim Hee Jin Chang Dae Yong Kim Seung-Yong Jeong Hyo Seong Choi Jae Hwan Oh | 2009 | International Journal of Colorectal Disease2009，，12： | 1 |
| 6 | Counterpropagation neural networks in structured engineering 显示文摘 | Hojja Adeli and Hyo Seon Park | 1995 | Journal of Structural Engineering1995，8，： | 1 |
| 7 | Optimization of space structures by neural dynamics 显示文摘 | Hojjat Adeli Hyo Seon Park | 1995 | Neural Networks1995，8，5： | 1 |
| 8 | Nonlinear system identification of smart structures under high impact loads显示文摘 | Kemal Sarp Arsava Yeesock Kim Tahar El-Korchi Hyo Seon Park | 2013 | Smart Materials and Structures2013，，5： | 1 |
| 9 | A unique feasible mode of prestress design for cable domes显示文摘 | Hoang Chi Tran Hyo Seon Park Jaehong Lee | 2012 | Finite Elements in Analysis & Design2012，，： | 1 |
| 10 | Comparison of clinical outcomes between culprit vessel only and multivessel percutaneous coronary intervention for ST-segment elevation myocardial infarction patients with multivessel coronary diseases显示文摘为圣片断举起的完全的 revascularization 的 BackgroundThe 临床的意义心肌的梗塞(STEMI )病人没有心脏性的吃惊,仍然在承认期间是从有 multivessel 疾病的朝鲜心肌的梗塞登记的 1406 个 STEMI 病人全部的 debatable.MethodsA 经历了主要经皮的冠的干预( PPCI )的人,被分析。我们使用了匹配的倾向分数(PSM ) 控制在犯人之间的基线特征的差别仅仅干预(CP ) 和 multivessel 经皮的冠的干预(MP ) ,并且在两倍容器疾病(DVD ) 和三倍的容器疾病(TVD ) 之间。在 discharge.ResultsTVD 病人显示出向的更高的发生以后,主要不利心脏的事件(向)被分析一年(14.2%对8.6%, P = 0.01 ), revascularization 的任何原因(10.6%对5.9%, P = 0.01 ),并且重复一种总线标准(9.5%对5.7%, P = 0.02 ),作为与 DVD 病人相比在一年在以后期间排出。 MP 有效地减少了向(7.3%对13.8%, P = 0.03 )与为死亡的一年,而是所有原因的 CP 相比(1.6%对3.2%, P = 0.38 ), MI (0.4%对0.8%, P = 1.00 ),并且 revascularization 的任何原因(5.3%对9.7%, P = 0.09 )在有 TVD 的病人更高显示出的二治疗 groups.ConclusionsSTEMI 是可比较的向的率,同样与 DVD 相比。MP 表现在 PPCI 期间或在为没有心脏性的吃惊的 STEMI 病人的承认期间特定在这个大放大数据库的向的显示出的更低的率。因此,没有心脏性的吃惊, MP 能为 STEMI 病人被看作一种有效治疗选择。 | Kwang Sun Ryu Hyun Woo Park Soo Ho Park Ho Sun Shon Keun Ho Ryu Dong Gyu Lee Mohamed EA Bashir Ju Hee Lee Sang Min Kim Sang Yeub Lee Jang Whan Bae Kyung Kuk Hwang Dong Woon Kim Myeong Chan Cho Young Keun Ahn Myung Ho Jeong Chong Jin Kim Jong Seon Park Young Jo Kim Yang Soo Jang Hyo Soo Kim Ki Bae Seung | 2015 | Journal of Geriatric Cardiology2015，12，3： | 1 |
| 11 | Optimal seismic retrofit model for steel moment resisting frames with brittle connections显示文摘Based on performance-based seismic engineering, this paper proposes an optimal seismic retrofit model for steel moment resisting frames(SMRFs) to generate a retrofit scheme at minimal cost. To satisfy the acceptance criteria for the Basic Safety Objective(BSO) specified in FEMA 356, the minimum number of upgraded connections and their locations in an SMRF with brittle connections are determined by evolutionary computation. The performance of the proposed optimal retrofitting model is evaluated on the basis of the energy dissipation capacities, peak roof drift ratios, and maximum interstory drift ratios of structures before and after retrofitting. In addition, a retrofit efficiency index, which is defined as the ratio of the increment in seismic performance to the required retrofitting cost, is proposed to examine the efficiencies of the retrofit schemes derived from the model. The optimal seismic retrofit model is applied to the SAC benchmark examples for threestory and nine-story SMRFs with brittle connections. Using the retrofit efficiency index proposed in this study, the optimal retrofit schemes obtained from the model are found to be efficient for both examples in terms of energy dissipation capacity, roof drift ratio, and maximum inter-story drift ratio. | Hyo Seon Park Se Woon Choi Byung Kwan Oh | 2018 | Earthquake Engineering and Engineering Vibration2018，17，4： | 0 |
| 12 | Optimal postoperative surveillance strategies for stage III colorectal cancer显示文摘BACKGROUND Optimal surveillance strategies for stage III colorectal cancer(CRC)are lacking,and intensive surveillance has not conferred a significant survival benefit.AIM To examine the association between surveillance intensity and recurrence and survival rates in patients with stage III CRC.METHODS Data from patients with pathologic stage III CRC who underwent radical surgery between January 2005 and December 2012 at Asan Medical Center,Seoul,Korea were retrospectively reviewed.Surveillance consisted of abdominopelvic computed tomography(CT)every 6 mo and chest CT annually during the 5 year follow-up period,resulting in an average of three imaging studies per year.Patients who underwent more than the average number of imaging studies annually were categorized as high intensity(HI),and those with less than the average were categorized as low intensity(LI).RESULTS Among 1888 patients,864(45.8%)were in HI group.Age,sex,and location were not different between groups.HI group had more advanced T and N stage(P=0.002,0.010,each).Perineural invasion(PNI)was more identified in the HI group(21.4%vs 30.3%,P<0.001).The mean overall survival(OS)and recurrence-free interval(RFI)was longer in the LI group(P<0.001,each).Multivariate analysis indicated that surveillance intensity[odds ratio(OR)=1.999;95%confidence interval(CI):1.680–2.377;P<0.001],pathologic T stage(OR=1.596;95%CI:1.197–2.127;P=0.001),PNI(OR=1.431;95%CI:1.192–1.719;P<0.001),and circumferential resection margin(OR=1.565;95%CI:1.083–2.262;P=0.017)in rectal cancer were significantly associated with RFI.The mean post-recurrence survival(PRS)was longer in patients who received curative resection(P<0.001).Curative resection rate of recurrence was not different between HI(29.3%)and LI(23.8%)groups(P=0.160).PRS did not differ according to surveillance intensity(P=0.802).CONCLUSION Frequent surveillance with CT scan do not improve OS in stage III CRC patients.We need to evaluate role of other surveillance method rather than frequent CT scans to detect recurrence for which curative treatment was possible because curative resection is the important to improve post-recurrence survival. | Min Young Park In Ja Park Hyo Seon Ryu Jay Jung Minsung Kim Seok-Byung Lim Chang Sik Yu Jin Cheon Kim | 2021 | World Journal of Gastrointestinal Surgery2021，13，9： | 0 |
| 13 | Cumulative incidence and risk factors for pouch adenomas associated with familial adenomatous polyposis following restorative proctocolectomy显示文摘BACKGROUND The emergence of restorative total proctocolectomy has significantly reduced the lifetime colorectal cancer risk associated with familial adenomatous polyposis(FAP).However,adenomas may develop in the ileal pouch over time and may even progress to carcinoma.We evaluated the cumulative incidence,time to development,and risk factors associated with ileal pouch adenoma.AIM To evaluate the cumulative incidence,time to development,and risk factors associated with pouch adenoma.METHODS In this retrospective,observational study conducted at a tertiary center,95 patients with FAP who underwent restorative proctocolectomy at our center between 1989 and 2018 were consecutively included.The mean follow-up period was 88 mo.RESULTS Pouch adenomas were found in 24(25.3%)patients,with a median time of 52 mo to their first formation.Tubular adenomas were detected in most patients(95.9%).There were no high-grade dysplasia or malignancies.Of the 24 patients with pouch adenomas,13 had all detected adenomas removed.Among the 13 patients who underwent complete adenoma removal,four(38.5%)developed recurrence.Among 11(45.8%)patients with numerous polyps within the pouch,seven(63.6%)exhibited progression of pouch adenoma.The cumulative risks of pouch adenoma development at 5,10,and 15 years after pouch surgery were 15.2%,29.6%,and 44.1%,respectively.Severe colorectal polyposis(with more than 1000 polyps)was a significant risk factor for pouch adenoma development(hazard ratio,2.49;95% confidence interval:1.04-5.96;P=0.041).CONCLUSION Pouch adenomas occur at a fairly high rate in association with FAP after restorative proctocolectomy,and a high colorectal polyp count is associated with pouch adenoma development. | Hyo Seon Ryu Chang Sik Yu Young Il Kim Jong Lyul Lee Chan Wook Kim Yong Sik Yoon In Ja Park Seok-Byung Lim Jin Cheon Kim | 2022 | World Journal of Gastroenterology2022，28，30： | 0 |
| 14 | Application of the Prague C and M criteria for endoscopic description of columnar-lined esophagus in South Korea显示文摘AIM:To ascertain whether the Prague circumferential(C) length and maximal(M) length criteria for grading the extent of Barrett's esophagus can be applied prior to its widespread application in South Korea.METHODS:Two hundred and thirteen consecutive cases with endoscopic columnar-lined esophagus(CLE) were included and classified according to the Prague C and M criteria.RESULTS:Of 213 cases with CLE, the distribution of maximum CLE lengths was: 0.5-0.9 cm in 99 cases(46.5%); 1.0-1.4 cm in 63 cases(29.6%); 1.5-1.9 cm in 15 cases(7.0%); 2.0-2.4 cm in 14 cases(6.6%); 2.5-2.9 cm in 1 case(0.5%); and 7.0 cm in 1 case(0.5%). Twenty cases(9.4%) had columnar islands alone. Two hundred and eight cases(97.7%) lacked the circumferential CLE component(C0Mx). Columnar islands were found in 70 cases(32.9%), of which 20 cases(9.4%) had columnar islands alone.CONCLUSION:In regions where most CLE patients display short or ultrashort tongue-like appearance, more detailed descriptions of CLE's in < 1.0 cm lengths and columnar islands, as well as avoidance of repeating the prefix 'C0' need to be considered in parallel with the widespread application of the Prague system in South Korea. | Jung Wan Choe Young Choon Kim Moon Kyung Joo Hyo Jung Kim Beom Jae Lee Ji Hoon Kim Jong Eun Yeon Jong-Jae Park Jae Seon Kim Kwan Soo Byun Young-Tae Bak | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，8： | 0 |
| 15 | Effects of corner modifications on wind loads and local pressures on walls of tall buildings显示文摘In this study, the aerodynamic characteristics of tall buildings with corner modifications (e.g., local wind force coefficients, mean pressure distributions, normalized power spectrum density, and extreme local pressure) were examined. Wind tunnel experiments were conducted to measure the wind pressures on building models with different heights and recessed corners of different ratios. At a wind direction of a = 0° (i.e., wind blowing on the front of a building), corner modifications effectively reduced wind forces in all cases. Specifically, small corner modification ratios reduced wind forces more effectively than their larger counterparts. However, corner modifications resulted in extreme local pressure on building surfaces. In addition, for small corner modification ratios, the probability of extreme local pressure occurring at a = 0° was high. This probability was also high for large corner modification ratios at a = 15° (i.e., wind blowing slightly obliquely on the front of a building) because wind blowing obliquely creates substantial vortex shedding on one side surface and extreme negative pressure over one building side surface. Results of computational fluid dynamic modeling were adopted to determine details of the aerodynamic characteristics of tall buildings with corner modifications. | K.T.Tse Gang Hu Jie Song Hyo Seon Park Bubryur Kim | 2021 | Building Simulation2021，14，4： | 0 |
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