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	题名	作者	年代	出处	被引量
1	Neutralizing antibodies in hepatitis C virus infection显示文摘Hepatitis C virus (HCV) is a major cause of hepatitis world-wide. The majority of infected individuals develop chronic hepatitis which can then progress to liver cirrhosis and hepatocellular carcinoma. Spontaneous viral clearance occurs in about 20%-30% of acutely infected individuals and results in resolution of infection without sequaelae. Both viral and host factors appear to play an important role for resolution of acute infection. A large body of evidence suggests that a strong, multispecific and long-lasting cellular immune response appears to be important for control of viral infection in acute hepatitis C. Due too the lack of convenient neutralization assays, the impact of neutralizing responses for control of viral infection had been less defined. In recent years, the development of robust tissue culture model systems for HCV entry and infection has finally allowed study of antibody-mediated neutralization and to gain further insights into viral targets of host neutralizing responses. In addition, detailed analysis of antibody-mediated neutralization in individual patients as well as cohorts with well defined viral isolates has enabled the study of neutralizing responses in the course of HCV infection and characterization of the impact of neutralizing antibodiesfor control of viral infection. This review will summarize recent progress in the understanding of the molecular mechanisms of antibody-mediated neutralization and its impact for HCV pathogenesis.	Mirjam B Zeisel Samira Fafi-Kremer Isabel Fofana Heidi Barth Franoise Stoll-Keller Michel Doffo■l Thomas F Baumert	2007	World Journal of Gastroenterology2007，13，36：	3
2	Mammography of ductal carcinoma in situ of the breast: Review of 909 cases with radiographic–pathologic correlations显示文摘	Béatrice Barreau Isabelle de Mascarel Caroline Feuga Gaétan MacGrogan Marie-Hélène Dilhuydy Véronique Picot Jean-Marie Dilhuydy Christine Tunon de Lara Emmanuel Bussières I. Schreer	2005	European Journal of Radiology2005，，1：	2
3	Molecular evlution of influenza A/ H3N2 viruses in the provinces of Quebec(Canada) during the 1997- 2000 period显示文摘	Isabelle H Yan L Michael B	2001	Virus Rese2001，77，：	1
4	Cloned plasmid DNA fragments as calibrators for controlling GMOs: Different real-time duplex quantitative PCR methods显示文摘	ISABEL T ERIK V B MARC D L	2004	Anal Bioanal Chem2004，378，5：	1
5	Molecular evlution of influenza AP H3N2 viruses in the provinces of Quebec(Canada)during the 1997-2000 period显示文摘	ISABELLE H YAN L MICHAEL B	2001	Virus Research2001，77，：	1
6	The neuropsychological phenotype of velocardiofacial syndrome(VCFS):Relationship to psychopathology显示文摘	Renee L O Neill Isabelle B	2006	Archives of Clinical Neuropsychology2006，21，2：	1
7	Molecular evolution of influenza A/H3N2 viruses in the provinces of Quebec(Canada)during the 1997-2000 period显示文摘	Yan L Michael B	2001	Virus Res2001，77，1：	1
8	Molecular evolution of influenza AH3N2 viruses in the provinces of Quebec (Canada) during the 1997 - 2000 period显示文摘	Isabelle H Yan L Michael B	2001	Virus Res2001，77，：	1
9	Impact of informal care giving on caregivers' health and quality of life: Analysis of gender inequali- ties显示文摘	Isabel L Unai M Amaia B	2008	Gac Sanit2008，22，5：	1
10	Molecular evolution of influ- enza A/H3N2 viruses in the province of Quebec(Canada) during the 1997-2000 peried显示文摘	ISABELLE H YAN L MICHAEL B	2001	Virus Res2001，77，1：	1
11	The effect of anchor voices and visible speech in training in the GRABS scale of perceptual evaluation of dysphonia显示文摘	FAUSTINO N B JUAN P D M ISABEL G L	2012	Acta Otorrinolaringológica Espa1ola2012，63，：	1
12	Synthesis and biological activities of high affinity taxane-based fluorescent probes 显示文摘	XUAN L ISABEL B RUTH M	2009	Bioorganic & Medicinal Chemistry Letters2009，197，：	1
13	Microstructural optimization of a zeolite membrane for organic vapor separation显示文摘	Zhiping L Griselda B Isabel D	2003	Science2003，300，：	1
14	Synthe- sis of phosphonodipeptidc conjugates of ursolic acid and their homologs显示文摘	Sheng L D Isabelle B Mohammed N	2008	Heteroat Chem2008，19，1：	1
15	Enriched environment delays theon set of hippocampal damage after global cerebral ischemia in rats 显示文摘	Andrey B Isabel S Yitao L	2003	Brain Res2003，964，1：	1
16	Micro structural optimization of a zeolite membrane for organic vapor aepaiation显示文摘	Zhiping L Gruelda B Isabel D	2003	Set2003，300，：	1
17	Molecular evolution of influenza AH3N2 viruses in the provinces of Quebec (Canada) during the 1997- 2000 period显示文摘	Isabelle H Yan L Michael B	2001	Virus Res2001，77，9：	1
18	Two new chlorinated naph- thalene glycosides from Rumex patientia 显示文摘	Ayse K Demirezer O L Isabelle B	2001	J Nat Prod2001，64，5：	1
19	Antioxidant activity and profiles of common fruits in Singapore显示文摘	ISABELLE M LEE B L MENG T L	2010	Food Chemistry2010，123，1：	1
20	维生素A限饲对伊比利亚猪肌内脂肪脂肪细胞的分化和脂肪酸组成的影响显示文摘研究的目的是探讨日粮维生素A水平是否与伊比利亚猪生长前期(活重35.8 kg)和育成期(活重158 kg)脂肪细胞分化或脂肪积累差异有关。选取活重16.3 kg的伊比利亚猪分配到两个日粮组,一组饲喂添加维生素A 10 000 U·kg-1的日粮(对照组);另一组不添加维生素A(VAR)。试验结果表明,维生素A的水平对猪生长性能和胴体品质没有影响。维生素A的早期限饲在生长早期极显著增加了背最长肌(LT)前脂肪细胞数量(P<0.001);并且增加育成期中性脂质含量,改善了其组成(较高的单不饱和脂肪酸和较低的饱和脂肪酸含量,P<0.05)。维生素A的限饲增加仔猪脂肪生成潜力,且不影响胴体性状。	Ayuso M óvilo C Rodríguez-Bertos A Rey A I Daza A Fenández A González-Bulnes A López-Bote C J Isabel B	2015	饲料博览2015，0，7：	1

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