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1Radiofrequency ablation for early oesophageal squamous neoplasia:Outcomes form United Kingdom registry显示文摘AIM:To report outcomes on patients undergoing radiofrequency ablation(RFA)for early oesophageal squamous neoplasia from a National Registry.METHODS:A Prospective cohort study from 8 tertiary referral centres in the United Kingdom.Patients with squamous high grade dysplasia(HGD)and early squamous cell carcinoma(ESCC)confined to the mucosa were treated.Visible lesions were removed by endoscopic mucosal resection(EMR)before RFA.Following initial RFA treatment,patients were followed up 3monthly.Residual flat dysplasia was treated with RFA until complete reversal dysplasia(CR-D)was achieved or progression to invasive Squamous cell cancer defined as infiltration into the submucosa layer or beyond.The main outcome measures were CR-D at 12 mo from start of treatment,long term durability,progression to cancer and adverse events.RESULTS:Twenty patients with squamous HGD/ESCC completed treatment protocol.Five patients(25%)had EMR before starting RFA treatment.CR-D was 50%at12 mo with a median of 1 RFA treatment,mean 1.5(range 1-3).Two further patients achieved CR-D with repeat RFA after this time.Eighty per cent with CR-D remain dysplasia free at latest biopsy,with median follow up 24 mo(IQR 17-54).Six of 20 patients(30%)progressed to invasive cancer at 1 year.Four patients(20%)required endoscopic dilatations for symptomatic structuring after treatment.Two of these patients have required serial dilatations thereafter for symptomatic dysphagia with a median of 4 dilatations per patient.The other 2 patients required only a single dilatation to achieve an adequate symptomatic response.One patient developed cancer during follow up after end of treatment protocol.CONCLUSION:The role of RFA in these patients re-mains unclear.In our series 50%patients responded at12 mo.These figures are lower than limited published data.Rehan J Haidry Mohammed A Butt Jason Dunn Matthew Banks Abhinav Gupta Howard Smart Pradeep Bhandari Lesley Ann Smith Robert Willert Grant Fullarton Morris John Massimo Di Pietro Ian Penman Marco Novelli Laurence B Lovat 2013World Journal of Gastroenterology2013,19,36:7
2The effects of ω3 fatty acids and coenzyme Q10 on blood pressure and heart rate in chronic kidney disease: a randomized controlled trial显示文摘Trevor A Mori Valerie Burke Ian B Puddey Ashley B Irish Christine A Cowpland Lawrence J Beilin Gursharan K Dogra Gerald F Watts 2009Journal of Hypertension2009,,9:1
3Diagnostic molecular biomarkers for malignant pleural effusions显示文摘Krishna B Sriram Vandana Relan Belinda E Clarke Edwina E Duhig Ian A Yang Rayleen V Bowman YC Gary Lee Kwun M Fong 2011Future Oncol2011,,6:1
4Modifiable Factors Associated With Improved Cardiac Arrest Survival in a Multicenter Basic Life Support/Defibrillation System: OPALS Study Phase I Results显示文摘Ian G Stiell George A Wells Valerie J DeMaio Daniel W Spaite Brian J Field Douglas P Munkley Marion B Lyver Lorraine G Luinstra Roxanne Ward 1999Annals of Emergency Medicine1999,,:1
5Electrolyte composition for Cu electrochemical mechanical planarization 显示文摘ABHINAV T CRAIG B IAN I S LI Y Z FRANCOIS D ALEX B JAMES M A 2008Journal of The Electrochemical Society2008,155,7:1
6Computer guided alignment II: optical system alignment using differential wavefront sampling 显示文摘Lee Hanshin Dalton Gavin B Tosh Ian A J 2007Optics Express2007,15,15:1
7Computational modeling of shock compression of power显示文摘David J B Ian D Meyers M A 2001Shock compression of condensed matter2001,23,:1
8Evaluating the vulnerability of surface waters to antibiotic contamination from varying wastewater treatment plant discharges显示文摘Angela L B Ian B B Diana S A 2006Environmental Pollution2006,142,:1
9流行病学和临床研究中数据缺失的多重填补:机会和陷阱显示文摘许多研究都存在缺失数据。JonathanJonathan A C Sterne Ian R White John B Carlin Michael Spratt Patrick Royston Michael G Kenward Angela M Wood James R Carpenter 张清(译) 张孔来(校) 2009英国医学杂志中文版2009,12,6:1
10Oligonueleotide primers for the detection of bioluminescent dinoflagellates reveal novel luciferase sequences and information on the molecular evolution of this gene显示文摘Andrea B Ian R Mark A M 2008J Phycol2008,,44:1
11Specific inhibition of PTEN expression reverses hyperglycemia in diabetic mice显示文摘Madeline B Robert A M Ian J Pf 2002Diabetes2002,51,4:1
12Cooperative spectrumsensing in cognitive radio networks 显示文摘IAN F A BRANDON F L RAVIKUMAR B 2011Physical Communication2011,4,1:1
13Vitamin C induced decomposition of lipid hydroperoxides to endogenous genotoxins显示文摘Seon H L Tomoyuki O E Ian A B 2001Science2001,292,15:1
14Service innovation in manufacturing firms:Evidence from Spain,显示文摘Llu??s Santamar??a a n Mar??a Jesu?s Nieto b Ian Miles c 2012Technovation2012,32,:1
15Clinical and financial bene-fits of utra-articular显示文摘Navendu Goyal Darren B Chen Ian A Harris 2016Journal of Ortho- paedic Surgery2016,24,1:1
16MLSR: a novel routing algorithmfor multilayered satellite IP networks显示文摘IAN F A EKICI E MICHAEL D B 2002IEEE/ ACM Transactions onNetworking2002,10,3:1
17Using Isochrone Surfaces in Travel Cost Models 显示文摘JULII S B ANDREW A L IAN J B 1997Journal of Transport Geography1997,5,2:1
18MLSR: a novel routing algorithm for multilayered satellite IP networks显示文摘Ian F A Eylem E Michael D B 2002IEEE/ACM Transactions on Networking2002,10,3:1
19The histori- cal fuel efficiency characteristics of regional aircraft from technological, operational, and cost perspectives显示文摘RAFFI B STEPHEN P LUKACHKO IAN A 2002Jour- nal of Air Transport Management2002,8,6:1
20Computational modeling of shock compression of power显示文摘David J B Ian D Meyers M A 2001Shock Compression of Condensed Matter2001,25,:1
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