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| 1 | Safety and effectiveness of propofol sedation during and after outpatient colonoscopy显示文摘AIM:To study the safety and effectiveness of propofol sedation for outpatient colonoscopy.METHODS:Propofol was given by bolus injection with an age-adjusted standard protocol consisting of 60 mg for patients < 70 years old,40 mg for patients age 70-89 years,and 20 mg for those ≥ 90 years,and additional injections of 20 mg propofol were given up to a maximum of 200 mg.The principal parameters were the occurrence of adverse events within 24 h after colonoscopy and overall satisfaction for this procedure.Secondary parameters included successful procedure,respiratory depression,and other complications.RESULTS:Consecutive patients were entered prospectively and all 2101 entered successfully completed outpatient colonoscopy.The mean dose of propofol used was 96.4 mg(range 40-200 mg).Younger patients required higher doses of propofol than older patients(20-40 years vs ≥ 61 years:115.3 ± 32 mg vs 89.7 ± 21 mg,P < 0.001).Transient supplemental oxygen supply was needed by five patients(0.2%);no other complications occurred.The questionnaires were completed by 1820(87%) of 2101 patients and most rated their overall satisfaction as excellent(80%) or good(17%).The majority(65%) of patients drove home or to their office after their colonoscopy.Most(99%) were willing to repeat the same procedure.No incidents occurred within 24 h after colonoscopy.CONCLUSION:Propofol sedation using a dose < 200 mg proved both safe and practical for outpatient colonoscopy. | Akira Horiuchi Yoshiko Nakayama Masashi Kajiyama Naoyuki Kato Tetsuya Kamijima Yasuyuki Ichise Naoki Tanaka | 2012 | World Journal of Gastroenterology2012，18，26： | 15 |
| 2 | Non-alcoholic fatty liver disease later diagnosed as myotonic dystrophy显示文摘BACKGROUND Myotonic dystrophy(MD)is sometimes accompanied by metabolic/endocrine disorders,including dyslipidemia,central obesity,and hypogonadism.Due to considerable individual differences in the severity and progression of myopathy,MD patients with minimal-to-mild muscle symptoms might be followed as having other diseases,such as non-alcoholic fatty liver disease(NAFLD).CASE SUMMARY A 40-year-old non-obese man without a history of regular ethanol consumption was referred to our hospital due to persistent liver dysfunction and hyperlipidemia.His body mass index was 23.4 kg/m2.Liver histology demonstrated macrovesicular steatosis,ballooned hepatocytes with eosinophilic inclusion bodies,and perisinusoidal fibrosis,leading to the diagnosis of nonalcoholic steatohepatitis(NASH).Although he had no discernable muscle pain or weakness,persistently high serum creatine kinase(CK)and myoglobin levels as well as the presence of frontal baldness,a hatched face,history of cataract surgery,and grip myotonia indicated the possibility of MD.Southern blotting of the patient’s DNA revealed the presence of CTG repeats,confirming the diagnosis.CONCLUSION When gastroenterologists encounter NAFLD/NASH patients,serum CK should be verified.If hyperCKemia,frontal baldness,a hatched face,history of cataract surgery,and grip myotonia are noted,the possibility of MD may be considered. | Naoki Tanaka Takefumi Kimura Naoyuki Fujimori Yasuyuki Ichise Kenji Sano Akira Horiuchi | 2020 | World Journal of Hepatology2020，12，9： | 3 |
| 3 | Age-related changes in D2 receptor binding with iodine-123-iodobenzofuran SPECT显示文摘 | Ichise M Ballinger JR Tanaka F | 1998 | J Nucl Med1998，39，9： | 1 |
| 4 | Observation on charging effects of non-conductive and uncoated materials by ion beam pre-bombardment in SEM显示文摘 | KANAYA K ICHISE N ADACHI K | 1992 | Micron and Microscopia Acta1992，23，： | 1 |
| 5 | PET imaging of brain with the β -amyloid probe,6-OH-BTA-1,in a transgenic mouse model of Alzheimer's disease显示文摘 | Toyama H 1 Ye D Ichise M | 2005 | Eur J Nucl Med Mol Imaging2005，32，： | 1 |
| 6 | Evaluation of anesthesia effects on[18F]FDG uptake in mouse brain and heart using small animal PET显示文摘 | Toyama H Ichise M Liow JS | | 0，，： | 1 |
| 7 | 9mTc -HMPAO SPECT, CT and MRI in the evaluation of patients with chronic traumatic brain injury:a correlation with neuropsychological performance 显示文摘 | Ichise M chung DG Wang P el al | 1994 | J Nucl Med1994，35，2： | 1 |
| 8 | PET imaging of brain with the β-amyloid probe, 6-OH-BTA-1,in a transgenic mice model of Alzheimer's disease显示文摘 | Toyama H Ye D Ichise M | 2005 | Eur J Nucl Med Mol Imaging2005，32，5： | 1 |
| 9 | An analog simulation of non-integer order transfer functions for analysis of electrode processes显示文摘 | NAGAYANAGI Y KOJIMA T | 1971 | Journal of Electroanulytical Chemistry Interfacial Hectrochemisry1971，33，： | 1 |
| 10 | Finding experts by link predic- tion in co-authorship networks显示文摘 | Pavlov M Ichise R | 2007 | FEWS2007，，290： | 1 |
| 11 | Dietary supplementation with fermented soybeans suppresses intimal thickening显示文摘 | Suzuki Y Kondo K Ichise H | 2003 | Nutrition2003，19，3： | 1 |
| 12 | Widespread decrease of nicotinic acetylcholine receptors in Parkinson's disease显示文摘 | Fujita M Ichise M Zoghbi SS | 2006 | Ann Neurol2006，59，1： | 1 |
| 13 | Hood-Assisted Colonoscopy Is More Effective in Detection of Colorectal Adenomas Than Narrow-Band Imaging显示文摘 | Akira Horiuchi Yoshiko Nakayama Naoyuki Kato Yasuyuki Ichise Masashi Kajiyama Naoki Tanaka | 2010 | Clinical Gastroenterology and Hepatology2010，，4： | 1 |
| 14 | Measurements of the parame- ter,p0 ,for the determinations of mixed iornic and N-Type electronic conduction in commercial zircania electrolytes 显示文摘 | Iwase M Ichise E Takeuchi M | 1984 | Trans Japan Ins Meltal1984，25，1： | 1 |
| 15 | Assessment of regional cerebral perfusion by 99 Tcm-HMPAO SPECT in chronic fatigue syndrome显示文摘 | Ichise M Salit IE Abbey SE | 1992 | Nucl Med Commun1992，13，10： | 1 |
| 16 | H - , N - and Kras co- operatively regulate lymphatic vessel growth by modula- ting VEGFR3 expression in lymphatic endothelial ceils in mice显示文摘 | Ichise T Yoshida N Ichise H | 2010 | Development2010，137，6： | 1 |
| 17 | An analog simulation of non-integer order transfer functions for analysis of electrode pro- cess 显示文摘 | ICHISE M NAGAYANAGI Y KOJIMA T | 1971 | Journal of Electroanalytical Chemistry and lnterfacial Elec- trochemistry1971，33，2： | 1 |
| 18 | PET imaging of brain with the beta-amyloid probe,6-OH-BTA-1,in a transgenic mouse model of Alzheimer's disease显示文摘 | Toyama H Ye D Ichise M | 2005 | Eur J Nucl Med Mol Imaging2005，32，： | 1 |
| 19 | PET quantification of lSF- florbetaben binding to 13-amyloid deposits in human brains显示文摘 | Becker GA Ichise M Barthel H | 2013 | J Nucl Med2013，54，5： | 1 |
| 20 | Relationship between the size of the bottle neck from ironin the main channel and the reactivity of catalase corresponding to the molecular size of substrates 显示文摘 | Hara I Ichise N Kojima K | 2007 | Biochemistry2007，46，1： | 1 |
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