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| 1 | Crystal structure of an integral membrane light-harvesting complex from photosynthtic bacteria显示文摘 | McDermott G Prince S M Freer A A Hawthorthwaite-Lawless A M Papiz M Z Cogdell R J Isaacs N W | 1995 | Nature1995，374，6： | 1 |
| 2 | Effect of pressure on processes modelling the Maillard reaction显示文摘 | Isaacs N S Coulson M | 1996 | Journal of Physical Organic Chemistry1996，，9： | 1 |
| 3 | Transcatheter aortic valve implantation in very elderly patients: immediate results and medium term follow-up显示文摘ObjectiveTo 评估立即的 transcatheter 在有严重、征兆的大动脉的狭窄的很老的病人的大动脉的阀门培植(TAVI ) 结果和中期的后续(作为).MethodsThis multicenter,观察、未来的学习在三所医院里被执行。我们包括了连续很老(>85 年) 病人与作为严重由 TAVI 对待。主要端点是在包括的二 years.ResultsThe 研究从任何原因评估死亡率有一个平均数的 160 个连续病人 87 ± 变老;2.1 年(从 85 ~ 94 年的范围) 和 18.8%± 的吝啬的逻辑 EuroSCORE;11.2% 与 57 (35.6%) 病人得分 ≥20% 。程序的成功率是 97.5% ,与 25 (15.6%) 与主要流血经历尖锐复杂并发症的病人(最经常) 。全球死亡率在住院期间是 8.8%(n = 14 ) 并且 30 天的死亡率是 10%(n = 16 ) 。中部在时期上面列在后面是 252.24 ±232.17 天。在后续时期期间, 28 (17.5%) 病人们死了(他们中的 17 个由于心脏的原因) 。估计的二年全面、心脏的幸存率使用 Kaplan-Meier 方法分别地是 71% 和 86.4% 。比例的危险回归给看了的考克斯可变 EuroSCORE ≥20 是与全面 mortality.ConclusionsTAVI 联系的唯一的变量在很老的病人的一张选择人口安全、有效。我们的调查结果支持在病人的这个复杂的组的这个新过程的采纳。 | Isaac Pascual Antonio J Mu oz-García Diego López-Otero Pablo Avanzas Manuel F Jimenez-Navarro Belén Cid-Alvarez Raquel del Valle Juan H Alonso-Briales Raimundo Ocaranza-Sanchez José M Hemández Ramiro Trillo-Nouche César Morís | 2015 | Journal of Geriatric Cardiology2015，12，4： | 1 |
| 4 | Phase Ⅲ,randomized,double-blind,placebo-controlled multicenter trial of daily everolimus plus weekly trastuzumab and vinorelbine in trastuzumab-resistant,advanced breast cancer (BOLERO-3)显示文摘 | O' Regan R Ozguroglu M Andre F Toi M Jerusalem G Wilks S Isaacs C Xu B Masuda N Arena FP Yardley D Yap YS Mukhopadhyay P Douma S El-Hashimy M Taran T Sahmoud T Lebwohl D Gianni L | | 0，，15： | 1 |
| 5 | Association of ambient air pollution with respiratory hospitalization in a government designated 'area of concern': the case of Windsor, Ontario 显示文摘 | Isaac N L Karen Y F Kevin M G | 2005 | Environ Health Perspeet2005，113，3： | 1 |
| 6 | The effect of high hydrostatic pressure on Salmonella thompson and Listeria monocytogenes examined by electron microscopy显示文摘 | Mackey B M Forestiere K Isaacs N S | 1994 | Letters in Applied Microbiology1994，19，： | 1 |
| 7 | Glycosylation restores survival of chilled blood platelets显示文摘 | HOFFMEISTER K M JOSEFSSON E C ISAAC N A | 2003 | Science2003，301，5639： | 1 |
| 8 | Endovenous la- ser treatment of the incompetent greater saphenous vein 显示文摘 | Min R J Zimmet S E Isaacs M N | 2001 | J Vase Interv Radio2001，12，10： | 1 |
| 9 | Does arthroplasty type influence knee jointproprloception A longitudinal prospeetlve study comparing total and unicompartmental arthroplasty 显示文摘 | ISAAC S M BARKER K L DANIAL I N | 2007 | Knee2007，14，3： | 1 |
| 10 | Effect of highhydrostatic pressure on the volatile components of a glucose-lysinemodel system显示文摘 | HILL V M ISAACS N S LEDWARD D A | 1999 | Agri Food Chem1999，47，9： | 1 |
| 11 | Reactions of phosphite esters and trisdialkylaminophosphines with 5-substituted 1,3,4-thiadiazol derivatives 显示文摘 | Arsanious M H N Isaac Y A Boulos L S | 2001 | Heteroatom Chemistry2001，12，7： | 1 |
| 12 | Effect of high hydrostatic pressure on the volatile components of a glucose-lysine model system 显示文摘 | Hill V M Isaac N S Ledward D A | 1999 | Journal of Agriculture and Food Chemistry1999，47，9： | 1 |
| 13 | Effect of pressure on processes modelling the Maillard reaction 显示文摘 | Isaacs N S Coulson M | 1996 | Journal of Physical Organic Chemistry1996，9，9： | 1 |
| 14 | Strong promotion by Na of Pt/',/-A12 03 catalysts opera- ted under simulated exhaust conditions 显示文摘 | KONSOLAKIS M MACLEOD N ISAAC J | 2000 | J Catal2000，193，2： | 1 |
| 15 | An evidence-based systematic review of saffron (Crocus sativus) by the Natural Standard Research Collaboration显示文摘 | Ulbricht C Conquer J Costa D Hollands W Iannuzzi C Isaac R Jordan JK Ledesma N Ostroff C Serrano JM Shaffer MD Varghese M | | 0，，01： | 1 |
| 16 | Association of ambient air pollution with respiratory hospitalization in a government-designated 'area of concern':the case of Windsor,Ontario显示文摘 | Isaac N L Karen Y F Kevin M G | 2005 | Environmental Health Perspectives2005，113，3： | 1 |
| 17 | Transgenic Anopheles stephensi coexpressing single-chain antibodies resist Plasmodiumfal- ciparum development显示文摘 | Isaacs AT Jasinskiene N Tretiakov M | 2012 | Proc Natl Acad Sci USA2012，109，28： | 1 |
| 18 | Association of ambient air pollution with respiratory hospitalization in a government-designated 'area of concern' : the case of Windsor, Ontario显示文摘 | ISAAC N L KAREN Y F KEVIN M G | 2005 | Environ Health Perspect2005，113，3： | 1 |
| 19 | P/M processing of gear component: Case studies of economic competitiveness 显示文摘 | Shah M N Isaacs J A | 2000 | Advances in Powder Metallurgy and Particulate Materials2000，，10： | 1 |
| 20 | Host plant evaluation behavior of Bemisia tabaci and its modification by external or internal uptake of imidacloprid显示文摘 | CAHILL M ISAACS R BYRNE D N | 1999 | Physiological Entomology1999，24，2： | 1 |
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