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| 1 | Hypertonicity:Clinical entities,manifestations and treatment显示文摘Hypertonicity causes severe clinical manifestations and is associated with mortality and severe short-term and longterm neurological sequelae. The main clinical syndromes of hypertonicity are hypernatremia and hyperglycemia.Hypernatremia results from relative excess of body sodium over body water. Loss of water in excess of intake,gain of sodium salts in excess of losses or a combination of the two are the main mechanisms of hypernatremia.Hypernatremia can be hypervolemic,euvolemic or hypovolemic. The management of hypernatremia addresses both a quantitative replacement of water and,if present,sodium deficit,and correction of the underlying pathophysiologic process that led to hypernatremia.Hypertonicity in hyperglycemia has two components,solute gain secondary to glucose accumulation in the extracellular compartment and water loss through hyperglycemic osmotic diuresis in excess of the losses of sodium and potassium. Differentiating between these two components of hypertonicity has major therapeutic implications because the first component will be reversed simply by normalization of serum glucose concentration while the second component will require hypotonic fluid replacement. An estimate of the magnitude of the relative water deficit secondary to osmotic diuresis is obtained by the corrected sodium concentration,which represents a calculated value of the serum sodium concentration that would result from reduction of the serum glucose concentration to a normal level. | Helbert Rondon-Berrios Christos Argyropoulos Todd S Ing Dominic S Raj Deepak Malhotra Emmanuel I Agaba Mark Rohrscheib Zeid J Khitan Glen H Murata Joseph I Shapiro Antonios H Tzamaloukas | 2017 | World Journal of Nephrology2017，6，1： | 2 |
| 2 | Human Streptococcus suis outbreak, Sichuan, China显示文摘 | Yu H J ing H Chen Z | 2006 | Emerg Infect Dis2006，12，6： | 1 |
| 3 | Tumor classification and marker gene prediction by feature selection and fuzzy c-means clustering using microarray data显示文摘 | JUNBAI W TROND H B INGE J | 2003 | BMC Bioinfor- matics2003，4，： | 1 |
| 4 | Ten-year postoperative results of penetrating ikeratoplasty显示文摘 | Ing J J Ing H H Nelson L R | 1998 | Ophthalmology1998，105，10： | 1 |
| 5 | High rate count-ing electronics for a thermal neutron analysis landmine detector 显示文摘 | CliffordE Ing H McFee J | 1999 | Proc SPIE1999，3769，： | 1 |
| 6 | A weighted-fractional model to european option pricing显示文摘 | SUN X YAN L J ING H | 2012 | Theoretical Mathematics & Applications2012，2，3： | 1 |
| 7 | A militarily fielded thermal neutron activation sensor for landmine detection显示文摘 | Clifford E T H McFee J E Ing H | 2007 | Nuclear Instruments and Methods in Physics Research A2007，579，： | 1 |
| 8 | Inhibition of Prostaglandin Biosynthesis by Tolfenamie Acid in vitro 显示文摘 | Inge - Britt Linden J Parantainen and H Vapaatolo | 1976 | Scand J Rheumatology1976，5，： | 1 |
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| 10 | A major ge- netic component of BSE susceptibility显示文摘 | Ju Schwarzenbacher H Williams J L | 2006 | BMC Biology2006，4，： | 1 |
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| 12 | H y -pox ia- inducible factor r egulates osteoclast- mediated boner esor ption: r ole of angiopoietin- lik e 4 显示文摘 | Know les H J Cleton- Jansen AM Kor sch ing E | 2010 | FASEB J2010，24，12： | 1 |
| 13 | Pentacyanoiron(Ⅱ) as an electron donor group for nonlinear optics: medium-responsive properties and comparisons with related pentaammineruthenium(Ⅱ) complexes 显示文摘 | Benjamin J C James A H Inge A | 2006 | J Am Chem Soc2006，128，12： | 1 |
| 14 | Electrospun silk fibroin nanofibers in different diameters support neurite out- growth and promote astrocyte migration显示文摘 | Qu J ing Wang Dan Wang H uihui et a l | 2013 | Journal of Biomedical Materials Research: Part A2013，101，9： | 1 |
| 15 | Pulmonary alveolar proteinosis in China:a systematic review of 241 cases显示文摘 | Xu Z J ing J Wang H | 2009 | Respirology2009，14，5： | 1 |
| 16 | Involvement of microRNA in AU-rich element-mediated mRNA instability显示文摘 | J ing Q H uang S Guth S | 2005 | Cell2005，120，5： | 1 |
| 17 | Visualisation of cell death in vivo in patients with acute myocardial infarction显示文摘 | Leo Hofstra Ing Han Liem Ewald A Dumont Hendricus H Boersma Waander L van Heerde Pieter A Doevendans Ebo DeMuinck HJJ Wellens Gerrit J Kemerink Chris PM Reutelingsperger Guido A Heidendal | 2000 | The Lancet . 2000 (9225)2000，，： | 1 |
| 18 | Expression of Ep-CAM shifts the state of cadherin-mediated adhesions from strong to weak显示文摘 | Manon J Winter Bas Nagelkerken Alexander E.E Mertens Hellen A.M Rees-Bakker Inge H Briaire-de Bruijn Sergey V Litvinov | 2003 | Experimental Cell Research2003，，1： | 1 |
| 19 | Voluntary exercise increases the new cell formation in the hippocampus of ovariectomized mice 显示文摘 | J IN J J ING H CHOI G | 2008 | Neurosci Lett2008，439，3： | 1 |
| 20 | Endo sco pic transnasa ldacry ocy sto rh ino stom y显示文摘 | M cDo no gh M M eir ing J H | 1989 | Laryng o 1 0 to1989，103，5： | 1 |
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