|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Fibrinogen and elastin bind to the same region within the A domain of fibronectin binding protein A, an MSCRAMM of Staphylococcus aureus显示文摘 | Fiona M.Keane AnthonyLoughman VivianaValtulina MarianBrennan PietroSpeziale Timothy J.Foster | 2006 | Molecular Microbiology2006，，3： | 1 |
| 2 | Fibrinogen and elastin bind to the same region within the A domain of fibronectin binding protein A, an MSCRAMM of Staphylococcus aureus显示文摘 | Fiona M.Keane AnthonyLoughman VivianaValtulina MarianBrennan PietroSpeziale Timothy J.Foster | 2006 | Molecular Microbiology2006，，3： | 1 |
| 3 | 黑胫病弱毒种和化学诱导剂诱导油菜对黑胫病抗性的比较研究显示文摘油菜黑胫病是由弱毒种Leptosphaeria bigloaosa和强毒种L.maculans混合感染引起的油菜严重病害.本文比较研究了弱毒种预接种、化学诱导剂水杨酸类似物(acibenzolar-S-methyl)和维他命K3类似物(menadione sodium bisulphite)处理所诱导的油菜对强毒种在抗性表型、组织细胞和RNA水平上的反应.诱导接种或化学处理后用强毒种接种.强毒种接种后8~21d,受诱导的植株其病斑扩展速度比水处理的对照显著降低,无论是受诱导的叶(局部效应)还是上部未诱导的叶(系统效应)均如此.强毒种接种后96h,观察到侵入叶组织的病原菌菌丝周围坏死的叶肉细胞,而在对照的植株上没有观测到.定量PCR分析表明,病害防御反应的标记基因PDF1.2,PR-1,NPR1,APX和CHB4在接种后0~96h的表达发生了变化.弱毒种预接种处理优先激活了茉莉酸,乙烯途径的基因表达,包括NPR1的诱导加强表达,这种效应不仅是局部的,而且是系统的. | 刘胜毅 刘仁虎 Akinwunmi O.Latunde-Dada Hans J.Cools Simon J.Foster 黄永菊 Bruce D.L.Fitt | 2007 | 科学通报2007，52，6： | 1 |
| 4 | A Class of Decomposable Poverty Measures显示文摘 | J.Foster J.Greer E.Thorbecke | | 0，，03： | 1 |
| 5 | Recent advances in targeting the“undruggable”proteins:from drugdiscover to clinical trials显示文摘Undruggable proteins are a class of proteins that are often characterized by large,complex structures or functions that are diffcult to interfere with using conventional drug design strategies.Targeting such undruggable targets has been considered also a great opportunity for treatment of human diseases and has attracted substantial efforts in the field of medicine.Therefore,in this review,we focus on the recent development of drug discovery targeting'undruggable'proteins and their application in clinic.To make this review well organized,we discuss the design strategies targeting the undruggable proteins,including covalent regulation,allosteric inhibition,protein-protein/DNA interaction inhibition,targeted proteins regulation,nucleic acid-based approach,immunotherapy and others. | Xin Xie Tingting Yu Xiang Li Nan Zhang Leonard J.Foster Cheng Peng Wei Huang Gu He | 2023 | Signal Transduction and Targeted Therapy2023，8，10： | 0 |
| 6 | 藏东昌都地区首次发现中侏罗世兽脚类恐龙行迹显示文摘藏东昌都地区阿涅塘化石点中侏罗世达布卡组滨湖相紫红色中-细砂岩中,发现以凸形迹完好地保存的4层恐龙足迹,包括Grallator类、大型兽脚类、小型兽脚类和小型蜥脚类等足迹类型,并构成两列完美的行迹.组成行迹T1的4个Grallator类足迹被命名为Grallator anietangensis isp.nov.,对其进行了详细的形态学分析,并讨论了造迹恐龙的大小和运动状态,这是Grallator类足迹在西藏地区的首次发现.组成行迹T2的9个大型兽脚类足迹被归为Theropoda igen.et isp.indet.,对该类足迹进行了形态描述和功能分析;这类足迹在中国是首次记录,其连续且清晰的尾迹表明造迹者并非处于正常运动状态,而是应对某种特殊境况的特别行为方式,即其正以昂起的前躯一边观察,一边以极低的速度前进,因前躯昂起,尾部相应下垂,从而留下尾迹.两列行迹均显示出造迹者正沿古昌都湖岸前进.中国迄今所发现的恐龙骨骼和Grallator类足迹化石主要表现为以西南地区为中心,再向四周不断发散的扩散模式,但Grallator类足迹化石综合提供的信息显示恐龙动物的扩散速度比骨骼化石反映的速度更快. | 李炎桂 姚华舟 William J.Foster 邢立达 王传尚 Asma Tahir Junaid Khan 安志辉 赵赫 王建雄 | 2022 | 地球科学2022，47，11： | 0 |
| 7 | Towards a unified nonlocal, peridynamics framework for the coarse-graining of molecular dynamics data with fractures显示文摘Molecular dynamics(MD)has served as a powerful tool for designing materials with reduced reliance on laboratory testing.However,the use of MD directly to treat the deformation and failure of materials at the mesoscale is still largely beyond reach.In this work,we propose a learning framework to extract a peridynamics model as a mesoscale continuum surrogate from MD simulated material fracture data sets.Firstly,we develop a novel coarse-graining method,to automatically handle the material fracture and its corresponding discontinuities in the MD displacement data sets.Inspired by the weighted essentially non-oscillatory(WENO)scheme,the key idea lies at an adaptive procedure to automatically choose the locally smoothest stencil,then reconstruct the coarse-grained material displacement field as the piecewise smooth solutions containing discontinuities.Then,based on the coarse-grained MD data,a two-phase optimizationbased learning approach is proposed to infer the optimal peridynamics model with damage criterion.In the first phase,we identify the optimal nonlocal kernel function from the data sets without material damage to capture the material stiffness properties.Then,in the second phase,the material damage criterion is learnt as a smoothed step function from the data with fractures.As a result,a peridynamics surrogate is obtained.As a continuum model,our peridynamics surrogate model can be employed in further prediction tasks with different grid resolutions from training,and hence allows for substantial reductions in computational cost compared with MD.We illustrate the efficacy of the proposed approach with several numerical tests for the dynamic crack propagation problem in a single-layer graphene.Our tests show that the proposed data-driven model is robust and generalizable,in the sense that it is capable of modeling the initialization and growth of fractures under discretization and loading settings that are different from the ones used during training. | H.Q.YOU X.XU Y.YU S.SILLING M.D'ELIA J.FOSTER | 2023 | Applied Mathematics and Mechanics(English Edition)2023，44，7： | 0 |
| 8 | 视频压缩技术:什么是MPEG?显示文摘数字音频性能优越,它以取样序列源的方式代替了模拟音频。目前人们普遍认为CD唱机(激光唱盘唱机)优于普通唱机、优于盒式磁带机和盘式磁带机。数字信号的记录和重放,从原理上讲没有信号的衰减和失真,其信噪比仅取决于数字处理本身,与记录和传输媒介无关。 视频数字化 将来,数字视频将象数字音频在音乐中取代模拟音频一样,取代模拟视频。当前高清晰度彩电(HDTV)引人注目(在美国它是采用数字技术的)。 | Edward J.Foster 赵卫滨 | 1995 | 今日电子1995，，6： | 0 |
| 9 | 视频压缩技术:什么是MPEG-2?显示文摘在早先的文章中(“音频视频”,1993年10月),我讨论了若干已经出台和即将出台的数字化视频系统:基于视频的电话会议;交互式多媒体;从中央数据库、5英寸音频光盘机(CD)上调用全动视频;从数字式盒式录相机(VCR)和摄像机调出话动电影等内容,但未涉及HDTV(高清晰度电视),并阐述过一个有效的数据压缩系统对于当前系统的运作和未来系统可能实现的必要性。 | Edward J.Foster 杨峨 | 1995 | 今日电子1995，，6： | 0 |
| 10 | 孩子的守护天使显示文摘从前,有个孩子准备要诞生了,他问上帝:“听说明天你就送我去人间了,但是,我这么弱小和无助,我在那儿怎么生活呢?” | Linda J.Foster | 2009 | 考试与评价(大学英语四级考试版)2009，，9： | 0 |
| 11 | 如何在多个市场经营报业集团——访美国甘乃特报业总裁Gary L.Watson显示文摘本文是一篇曾刊于《现代广告》1997年第6期的专题报道,当时就有业界人士称赞该杂志刊登此文是广开思路,能够较早地关注国外报团的业务管理,因为就在此文刊登的前一年,国内才有了首家报业集团。时隔六年,集团化已经成了中国报业发展的一大趋势,但是目前集团化运营的过程中仍有诸多缺失磕绊。他山之石,可以攻玉,本文中提到的多市场经营优势、如何收购新业务、以人力资源管理为核心的经营管理原则、报业结构调整,特别是'经营变革'的企业理念,现在看来仍是实用且富有新意的。特转载于此,希望能对报业同仁有所裨益。 | Michelle J.Foster 贾淑倩 | 2003 | 中国报业2003，0，3： | 0 |
| 12 | Tiny insects against the weather flight and foraging patterns of Frankliniella schultzei (Thripidae) not altered by onset of rainfall显示文摘To survive in nature,organisms may need to take direct action to mitigate specific dangers from their environmental surroundings.Tiny flying insects are thought to be at particular risk from rainfall that would be of negligible concern to larger animals.The study species Frankliniella schultzei is a thrips that inhabits flowers and feeds mostly on petal tissue and pollen.While found to respond in the laboratory to decreases in atmospheric pressure associated with cyclonic conditions (rather than merely heavy rainfall),their responses to conditions preceding rainfall have not been tested in the field.Initial field sampling investigated the relationship between floral development and sites at which male,female,and larval thrips were generally present on sunny days.We then designed a sampling strategy to test if these thrips can anticipate imminent rainfall or storms and so seek shelter deep within flowers,by sampling host flowers (in sections)on multiple days with different weather conditions.Sticky traps were used to intercept thrips in flight,thus providing a measure of flight behavior across different days.The initial sampling found adult thrips primarily at the petal apex of anthesis-stage flowers where pollen is distributed. We subsequently found that rainfall,atmospheric pressure change,temperature,humidity and wind had no effect on flight behavior of E schultzei,or on their positions within flowers.These findings suggest rainfall is not a serious hazard for them.Perhaps thrips can survive raindrop collisions during flight,as impacts with water droplets are not expected to break the surface tension. | Lachlan C.Jones Brodie J.Foster Michelle A.Rafter Gimme H.Walter | 2018 | Insect Science2018，25，6： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员